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Volumn 33, Issue 6, 2012, Pages 2079-2082

One-pot synthesis of 5-hydroxypyrrolin-2-one derivatives from modified morita-baylis-hillman adducts via a consecutive cui-mediated aerobic oxidation, allylic iodination, hydration of nitrile, and lactamization

Author keywords

5 hydroxypyrrolin 2 ones; Aerobic oxidation; Cui; Morita baylis hillman adducts

Indexed keywords


EID: 84862530759     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2012.33.6.2079     Document Type: Article
Times cited : (8)

References (55)
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  • 18
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    • a
    • For the selected synthesis and biological activity of 5-hydroxypyrrolin-2-one moiety-containing substances, see: (a) Ma, S.; Xie, H. Org. Lett. 2000, 2, 3801-3803.
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    • Ma, S.1    Xie, H.2
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    • a
    • For the introduction of a nucleophile at the secondary position of MBH adducts via a DABCO salt, see: (a) Chung, Y. M.; Gong, J. H.; Kim, T. H.; Kim, J. N. Tetrahedron Lett. 2001, 42, 9023-9026.
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    • Chung, Y.M.1    Gong, J.H.2    Kim, T.H.3    Kim, J.N.4
  • 39
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    • a
    • For the related copper-mediated cyclization-halogenation reactions, see: (a) Yazici, A.; Pyne, S. G. Tetrahedron Lett. 2011, 52, 1398-1400.
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    • a
    • For our recent reports on the hydration of nitriles to amides, see: (a) Kim, E. S.; Lee, H. S.; Kim, J. N. Tetrahedron Lett. 2009, 50, 6286-6289.
    • (2009) Tetrahedron Lett. , vol.50 , pp. 6286-6289
    • Kim, E.S.1    Lee, H.S.2    Kim, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.