Circadian rhythm disruption in severe sepsis: The effect of ambient light on urinary 6-sulfatoxymelatonin secretion

Intensive Care Medicine

Volumn 38, Issue 5, 2012, Pages 804-810

  Verceles, Avelino C ^a   Silhan, Leann ^a   Terrin, Michael ^a   Netzer, Giora ^a   Shanholtz, Carl ^a   Scharf, Steven M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Critical illness; Keywords Sepsis Circadian rhythm; Melatonin Light

Indexed keywords

6 HYDROXYMELATONIN O SULFATE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; DEXMEDETOMIDINE; MELATONIN; NORADRENALIN; PHENYLEPHRINE; PROPOFOL; VASOPRESSIN;

ADULT; AMBIENT LIGHT; APACHE; ARTICLE; ARTIFICIAL VENTILATION; BACTEREMIA; BODY MASS; CELLULITIS; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM DISRUPTION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONCENTRATION (PARAMETERS); DRUG EFFECT; FEMALE; HORMONE RELEASE; HORMONE URINE LEVEL; HUMAN; INTENSIVE CARE UNIT; LIGHT; MALE; PNEUMONIA; SEPSIS; SEVERE SEPSIS; TUBE FEEDING; URINALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHRONOBIOLOGY DISORDERS; CIRCADIAN RHYTHM; CRITICAL ILLNESS; FEMALE; HUMANS; INTENSIVE CARE UNITS; LIGHT; MALE; MELATONIN; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; SEPSIS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84862518671     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2494-3     Document Type: Article

References (41)

1. Hilton BA (1976) Quantity and quality of patients' sleep and sleep-disturbing factors in a respiratory intensive care unit. J Adv Nurs 1:453-468
2. Freedman NS, Gazendam J, Levan L, Pack AI, Schwab RJ (2001) Abnormal sleep/wake cycles and the effect of environmental noise on sleep disruption in the intensive care unit. Am J Respir Crit Care Med 163:451-457
3. Gabor JY, Cooper AB, Crombach SA, Lee B, Kadikar N, Bettger HE, Hanly PJ (2003) Contribution of the intensive care unit environment to sleep disruption in mechanically ventilated patients and healthy subjects. Am J Respir Crit Care Med 167:708-715
4. Tamburri LM, DiBrienza R, Zozula R, Redeker NS (2004) Nocturnal care interactions with patients in critical care units. Am J Crit Care 13:102-112
5. Haimovich B, Calvano J, Haimovich AD, Calvano SE, Coyle SM, Lowry SF (2010) In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes. Crit Care Med 38:751-758
6. Irwin M, McClintick J, Costlow C, Fortner M, White J, Gillin JC (1996) Partial night sleep deprivation reduces natural killer and cellular immune responses in humans. FASEB J 10:643-653
7. Spiegel K, Sheridan JF, Van Cauter E (2002) Effect of sleep deprivation on response to immunization. JAMA 288:1471-1472
8. Everson CA, Toth LA (2000) Systemic bacterial invasion induced by sleep deprivation. Am J Physiol Regul Integr Comp Physiol 278:R905-R916
9. Valente M, Placidi F, Oliveira AJ, Bigagli A, Morghen I, Proietti R, Gigli GL (2002) Sleep organization pattern as a prognostic marker at the subacute stage of post-traumatic coma. Clin Neurophysiol 113:1798-1805
10. Mundigler G, Delle-Karth G, Koreny M, Zehetgruber M, Steindl-Munda P, Marktl W, Ferti L, Siostrzonek P (2002) Impaired circadian rhythm of melatonin secretion in sedated critically ill patients with severe sepsis. Crit Care Med 30:536-540
11. Czeisler CA, Allan JS, Strogatz SH, Ronda JM, Sánchez R, R?́os CD, Freitag WO, Richardson GS, Kronauer RE (1986) Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle. Science 233:667-671
12. Lewy AJ, Sack RL, Miller LS, Hoban TM, Singer CM, Samples JR, Krauss GL (1986) The use of plasma melatonin levels and light in the assessment and treatment of chronobiologic sleep and mood disorders. J Neural Transm SUPPL. 21:311-322
13. Bourne RS, Mills GH (2006) Melatonin: possible implications for the postoperative and critically ill patient. Intensive Care Med 32:371-379. doi: 10.1007/s00134-005-0061
14. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G (2003) 2001 SCCM/ESICM/ACCP/ ATS/SIS International Sepsis Definitions Conference. Intensive Care Med 29:530-538. doi: 10.1007/s00134-003-1662
15. Dellinger RP, Levy MM, Carlet JM et al (2008) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 36:296-327
16. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829
17. Bojkowski CJ, Arendt J (1990) Factors influencing urinary 6-sulphatoxymelatonin, a major melatonin metabolite, in normal human subjects. Clin Endocrinol 33:435-444
18. Utiger RD (1992) Melatonin-the hormone of darkness. N Engl J Med 327:1377-1379
19. Barassin S, Kalsbeek A, Saboureau M, Bothorel B, Vivien-Roels B, Malan A, Buijs RM, Pevet P (2000) Potentiation effect of vasopressin on melatonin secretion as determined by trans-pineal microdialysis in the rat. J Neuroendocrinol 12:61-68
20. Dispersyn G, Pain L, Touitou Y (2010) Propofol anesthesia significantly alters plasma blood levels of melatonin in rats. Anesthesiology 112:333-337
21. Sessler CN, Gosnell M, Grap MJ, Brophy GT, O'Neal PV, Keane KA, Tesoro EP, Elswick RK (2002) The Richmond agitation-sedation scale: validity and reliability in adult intensive care patients. Am J Respir Crit Care Med 166:1338-1344
22. Perras B, Meier M, Dodt C (2007) Light and darkness fail to regulate melatonin release in critically ill humans. Intensive Care Med 33:1954-1958. doi: 10.1007/s00134-007-0769
23. Perras B, Kurowski V, Dodt C (2006) Nocturnal melatonin concentration is correlated with illness severity in patients with septic disease. Intensive Care Med 32:624-625. doi: 10.1007/s00134-006-0069
24. Shilo L, Dagan Y, Smorjik Y, Weinberg U, Dolev S, Komptel B, Balaum H, Shenkman L (1999) Patients in the intensive care unit suffer from severe lack of sleep associated with loss of normal melatonin secretion pattern. Am J Med Sci 317:278-281
25. Olofsson K, Alling C, Lundberg D, Malmros C (2004) Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients. Acta Anaesthesiol Scand 48:679-684
26. Bojkowski CJ, Arendt J, Shih MC, Markey SP (1987) Melatonin secretion in humans assessed by measuring its metabolite, 6-sulfatoxymelatonin. Clin Chem 33:1343-1348
27. Maestronin GJ, Conti A, Pierpaoli W (1989) Melatonin, stress, and the immune system. Pineal Res Rev 7:203-226
28. Tan DX, Chen L-D, Poeggeler B, Manchester LC, Reiter RJ (1993) Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1:57-60
29. Kato K, Asai S, Murai I, Nagata T, Takahashi Y, Komuro S, Iwasaki A, Ishikawa K, Arakawa Y (2001) Melatonin's gastroprotective and antistress roles involve both central and peripheral effects. J Gastroenterol 36:91-95
30. Lewy AJ, Wehr TA, Goodwin FK, Newsome DA, Markey SP (1980) Light suppresses melatonin secretion in humans. Science 210:1267-1269
31. Zeitzer JM, Dijk DJ, Kronauer R, Brown E, Czeisler C (2000) Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J Physiol 526(Pt 3):695-702
32. Crasson M, Kjiri S, Colin A, Kjiri K, L'Hermite-Baleriaux M, Ansseau M, Legros JJ (2004) Serum melatonin and urinary 6-sulfatoxymelatonin in major depression. Psychoneuroendocrinology 29:1-12. doi: 10.1016/S0306-4530(02)00123-3
33. Reiter RJ (1995) The pineal gland and melatonin in relation to aging: a summary of the theories and of the data. Exp Gerontol 30:192-212
34. Frisk U, Olsson J, Nylen P, Hahn RG (2004) Low melatonin excretion during mechanical ventilation in the intensive care unit. Clin Sci (Lond) 107:47-53
35. Broughton R, Baron R (1978) Sleep patterns in the intensive care unit and on the ward after acute myocardial infarction. Electroencephalogr Clin Neurophysiol 45:348-360
36. Yildizeli B, Ozyurtkan MO, Batirel HF, Kuşcu K, Bekirog?lu N, Yüksel M (2005) Factors associated with postoperative delirium after thoracic surgery. Ann Thorac Surg 79:1004-1009
37. Weinhouse GL, Schwab RJ, Watson PL, Patil N, Vaccaro B, Pandharipande P, Ely EW (2009) Bench-to-bedside review: Delirium in ICU patients-importance of sleep deprivation. Crit Care 13:234. doi:10.1186/cc8131
38. Shirani A, St Louis EK (2009) Illuminating rationale and uses for light therapy. J Clin Sleep Med 5:155-163
39. Boivin DB, Czeisler CA (1998) Resetting of circadian melatonin and cortisol rhythms in humans by ordinary room light. Neuroreport 9:779-782
40. Okada K, Yano M, Doki Y, Azama T, Iwanaga H, Miki H, Nakayama M, Miyata H, Takiguchi S, Fujiwara Y, Yasuda T, Ishida N, Monden M (2008) Injection of LPS causes transient suppression of biological clock genes in rats. J Surg Res 145:5-12
41. Hebert M, Dumont M, Paquet J (1998) Seasonal and diurnal patterns of human illumination under natural conditions. Chronobiol Int 15:59-70