Hemostatic resuscitation with plasma and platelets in trauma

Journal of Emergencies, Trauma and Shock

Volumn 5, Issue 2, 2012, Pages 120-125

  Johansson, Pär I ^a   Oliveri, Roberto S ^a   Ostrowski, Sisse R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Coagulopathy; damage control resuscitation; FFP; meta analysis; platelet concentrate; RBC; transfusion ratios; trauma

Indexed keywords

EID: 84862517014     PISSN: 09742700     EISSN: 0974519X     Source Type: Journal    
DOI: 10.4103/0974-2700.96479     Document Type: Article

References (41)

1. Hardy JF, de Moerloose P, Samama M. Massive transfusion and coagulopathy: Pathophysiology and implications for clinical management. Can J Anaesth 2004;51:293-310. (Pubitemid 38701939)
2. Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, et al. Acute coagulopathy of trauma: Hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma 2008;64:1211-7. (Pubitemid 351671214)
3. Johansson PI, Hansen MB, Sorensen H. Transfusion practice in massively bleeding patients: Time for a change? Vox Sang 2005;89:92-6. (Pubitemid 41153025)
4. Hess JR, Holcomb JB, Hoyt DB. Damage control resuscitation: The need for specific blood products to treat the coagulopathy of trauma. Transfusion 2006;46:685-6.
5. Deeks JJ, Higgins JP, Altman DG. Analysing data and undertaking meta-analyses. In: Higgins JP, Green S, editors. Cochrane handbook for systematic reviews of interventions. Chichester: John Wiley & Sons; 2008. pp. 243-96
6. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88. (Pubitemid 17189972)
7. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539-58. (Pubitemid 34746062)
8. Borgman MA, Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007;63:805-13. (Pubitemid 350287298)
9. Duchesne JC, Hunt JP, Wahl G, Marr AB, Wang YZ, Weintraub SE, et al. Review of current blood transfusions strategies in a mature level I trauma center: Were we wrong for the last 60 Years? J Trauma 2008;65:272-8.
10. Maegele M, Lefering R, Paffrath T, Tjardes T, Simanski C, Bouillon B, et al. Red blood cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiply injury: A retrospective analysis from the trauma registry of the deuthche gesellschaft für unfallschirurie. Vox Sang 2008;95:112-9. (Pubitemid 351951900)
11. Snyder CW, Weinberg JA, McGwin G Jr, Melton SM, George RL, Reiff DA, et al. The relationship of blood product ratio to mortality: Survival benefit or survival bias? J Trauma 2009;66:358-64.
12. Teixeira GR, Inaba K, Shulman I, Salim A, Demetriades D, Brown C, et al. Impact of plasma transfusion in massively transfused trauma patients. J Trauma 2009;66:693-7.
13. Duchesne JC, Islam TM, Stuke L, Timmer JR, Barbeau JM, Marr AB, et al. Hemostatic resuscitation during surgery improves survival in patients with traumatic-induced coagulopathy. J Trauma 2009;67:33-9.
14. Holcomb JB, Wade CE, Michalek J, Chisholm GB, Zarzabal LA, Schreiber MA, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg 2008;248:447-58.
15. Stinger HK, Spinella PC, Perkins JG, Grathwohl KW, Salinas J, Martini WZ, et al. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital. J Trauma 2008;64(2 Suppl):S79-85.
16. Shaz BH, Dente CJ, Nicholas J, MacLeod JB, Young AN, Easley K, et al. Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. Transfusion 2010;50:493-500.
17. Schnüriger B, Inaba K, Abdelsayed GA, Lustenberger T, Eberle BM, Barmparas G, et al. The impact of platelets on the progression of traumatic intracranial hemorrhage. J Trauma 2010;68:881-5.
18. Cotton BA, Au BK, Nunez TC, Gunter OL, Robertson AM, Young PP. Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications. J Trauma 2009;66:41-9.
19. Perkins JG, Cap AP, Spinella PC, Blackbourne LH, Grathwohl KW, Repine TB, et al. An evaluation of the impact of apheresis platelets used in the setting of massively transfused trauma patients. J Trauma 2009;66 (4 Suppl):S77-85.
20. Dente CJ, Shaz BH, Nicholas JM, Harris RS, Wyrzykowski AD, Patel S, et al. Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center. J Trauma 2009;66:1616-24.
21. Riskin DJ, Tsai TC, Riskin L, Hernandez-Boussard T, Purtill M, Maggio PM, et al. Massive transfusion protocols: The role of aggressive resuscitation versus product ratio in mortality reduction. J Am Coll Surg 2009;209:198-205.
22. Duchesne JC, Kimonis K, Marr AB, Rennie KV, Wahl G, Wells JE, et al. Damage control resuscitation in combination with damage control laparotomy: A survival advantage. J Trauma 2010;69:46-52.
23. van PY, Sambasivan CN, Wade CE, Jones JA, Holcomb JB, Schreiber MA, et al. High transfusion ratios are not associated with increased complication rates in patients with severe extremity injuries. J Trauma 2010;69 Suppl 1:S64-8.
24. Scalea TM, Bochicchio KM, Lumpkins K, Hess JR, Dutton R, Pyle A, et al. Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients. Ann Surg 2008;248:578-84.
25. Magnotti LJ, Zarzaur BL, Fischer PE, Williams RF, Myers AL, Bradburn EH, et al. Improved survival after hemostatic resuscitation: Does the emperor have no clothes? J Trauma 2011;70:97-102.
26. Perkins JG, Cap AP, Weiss BM, Reid TJ, Bolan CD. Massive transfusion and nonsurgical hemostatic agents. Crit Care Med 2008;36 (7 Suppl):S325-39.
27. Dutton RP, Stansbury LG, Leone S, Kramer E, Hess JR, Scalea TM. Trauma mortality in mature trauma systems: Are we doing better? An analysis of trauma mortality patterns, 1997-2008. J Trauma 2010;69:620-6.
28. Kashuk JL, Moore EE, Johnson JL, Haenel J, Wilson M, Moore JB, et al. postinjury life threatening coagulopathy: Is 1:1 fresh frozen plasma: Packed red blood cells the answer? J Trauma 2008;65:261-71.
29. Davenport R, Curry N, Manson J, De'Ath H, Coates A, Rourke C, et al. Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2. J Trauma 2011;70:90-6.
30. Frith D, Goslings JC, Gaarder C, Maegele M, Cohen MJ, Allard S, et al. Definition and drivers of acute traumatic coagulopathy: Clinical and experimental investigations. J Thromb Haemost 2010;8:1919-25.
31. Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, et al. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma? Ann Surg 2008;247:320-6. (Pubitemid 351156777)
32. Johansson PI, Stensballe J, Rasmussen LS, Ostrowski SR. A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis and increased mortality in trauma patients. Ann Surg 2011;254(2):194-200.
33. Pati S, Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, et al. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. J Trauma 2010;65:55-3.
34. Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, et al. Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock. Anesth Analg 2011;112(6):1289-95.
35. Johansson PI, Stensballe J, Rosenberg I, Hilsøv T, Jørgensen L, Secher NH. Proactive administration of platelets and plasma for patients with a ruptured abdominal aortic aneurysm: Evaluating a change in transfusion practice. Transfusion 2007;47:593-8. (Pubitemid 46449619)
36. Salooja N, Perry DJ. Thrombelastography. Blood Coagul Fibrinolysis 2001;12:327-37. (Pubitemid 32730491)
37. Di Benedetto P, Baciarello M, Cabetti L, Martucci M, Chiaschi A, Bertini L. Thrombelastography. Present and future perspectives in clinical practice. Minerva Anestesiol 2003;69:501-15.
38. Plotkin AJ, Wade CE, Jenkins DH, Smith KA, Noe JC, Park MS, et al. A reduction in clot formation rate and strength assessed by thrombelastography is indicative of transfusion requirements in patients with penetrating injuries. J Trauma 2008;64(2 Suppl):S64-8.
39. Carroll RC, Craft RM, Langdon RJ, Clanton CR, Snider CC, Wellons DD, et al. Early evaluation of acute traumatic coagulopathy by thrombelastography. Transl Res 2009;154:34-9.
40. Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al. Management of bleeding following major trauma: An updated European guideline. Crit Care 2010;14:R52.
41. Hess JR, Johansson PI, Holcomb JB. Trauma and massive transfusion. Transfusion Therapy: Clinical principles and practice. In: Mintz PD, editor. 3rd ed. Bethesda: AABB Press; 2010.