메뉴 건너뛰기




Volumn 28, Issue 3, 2012, Pages 399-411

Etiology and Significance of Thrombocytopenia in Critically Ill Patients

Author keywords

Critically ill; Heparin induced thrombocytopenia; Intensive care unit; Platelets; Thrombocytopenia

Indexed keywords

ABCIXIMAB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; FC RECEPTOR; FRESH FROZEN PLASMA; HEPARIN; IMMUNOGLOBULIN G; RHESUS D ANTIBODY; TICLOPIDINE; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 84862516883     PISSN: 07490704     EISSN: 15578232     Source Type: Journal    
DOI: 10.1016/j.ccc.2012.04.007     Document Type: Review
Times cited : (31)

References (72)
  • 1
    • 77953037881 scopus 로고    scopus 로고
    • Drug-induced thrombocytopenia in critically ill patients
    • Priziola J.L., Smythe M.A., Dager W.E. Drug-induced thrombocytopenia in critically ill patients. Crit Care Med 2010, 38(6 Suppl):S145-S154.
    • (2010) Crit Care Med , vol.38 , Issue.6 SUPPL.
    • Priziola, J.L.1    Smythe, M.A.2    Dager, W.E.3
  • 2
    • 1842335099 scopus 로고    scopus 로고
    • Incidence and risk factors of thrombocytopenia in critically ill trauma patients
    • Hanes S.D., Quarled D.A., Boucher B.A. Incidence and risk factors of thrombocytopenia in critically ill trauma patients. Ann Pharmacother 1997, 31:285-289.
    • (1997) Ann Pharmacother , vol.31 , pp. 285-289
    • Hanes, S.D.1    Quarled, D.A.2    Boucher, B.A.3
  • 3
    • 0032917539 scopus 로고    scopus 로고
    • Potential risk factors associated with thrombocytopenia in a surgical intensive care unit
    • Cawley M.J., Wittbrodt E.T., Boyce E.G., et al. Potential risk factors associated with thrombocytopenia in a surgical intensive care unit. Pharmacotherapy 1999, 19:108-113.
    • (1999) Pharmacotherapy , vol.19 , pp. 108-113
    • Cawley, M.J.1    Wittbrodt, E.T.2    Boyce, E.G.3
  • 4
    • 0036348390 scopus 로고    scopus 로고
    • Thrombocytopenia in patients in the medical intensive care unit: bleeding prevalence, transfusion requirements and outcome
    • Strauss R., Wehler M., Mehler K., et al. Thrombocytopenia in patients in the medical intensive care unit: bleeding prevalence, transfusion requirements and outcome. Crit Care Med 2002, 30:1765-1771.
    • (2002) Crit Care Med , vol.30 , pp. 1765-1771
    • Strauss, R.1    Wehler, M.2    Mehler, K.3
  • 5
    • 79551583832 scopus 로고    scopus 로고
    • The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review
    • Hui P., Cook D.J., Lim W., et al. The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review. Chest 2011, 139:271-278.
    • (2011) Chest , vol.139 , pp. 271-278
    • Hui, P.1    Cook, D.J.2    Lim, W.3
  • 6
    • 0034007257 scopus 로고    scopus 로고
    • Evaluation and management of drug-induced thrombocytopenia in the acutely ill patient
    • Wazny L.D., Ariano R.E. Evaluation and management of drug-induced thrombocytopenia in the acutely ill patient. Pharmacotherapy 2000, 20:292-307.
    • (2000) Pharmacotherapy , vol.20 , pp. 292-307
    • Wazny, L.D.1    Ariano, R.E.2
  • 8
    • 0029122616 scopus 로고
    • Thrombocytopenia in intensive care patients: a comprehensive analysis of risk factors in 314 patients
    • Bonfiglio M.F., Traeger S.M., Kier K.L., et al. Thrombocytopenia in intensive care patients: a comprehensive analysis of risk factors in 314 patients. Ann Pharmacother 1995, 29:835-842.
    • (1995) Ann Pharmacother , vol.29 , pp. 835-842
    • Bonfiglio, M.F.1    Traeger, S.M.2    Kier, K.L.3
  • 9
    • 0035990358 scopus 로고    scopus 로고
    • Risk markers for thrombocytopenia in critically ill patients: a prospective analysis
    • Shalansky S.J., Verma A.K., Levine M., et al. Risk markers for thrombocytopenia in critically ill patients: a prospective analysis. Pharmacotherapy 2002, 22:803-813.
    • (2002) Pharmacotherapy , vol.22 , pp. 803-813
    • Shalansky, S.J.1    Verma, A.K.2    Levine, M.3
  • 10
    • 37049009297 scopus 로고    scopus 로고
    • Thrombocytopenia in septic shock patients-a prospective observational study of incidence, risk factors and correlation with clinical outcome
    • Sharma B., Sharma M., Majumder M., et al. Thrombocytopenia in septic shock patients-a prospective observational study of incidence, risk factors and correlation with clinical outcome. Anaesth Intensive Care 2007, 35:874-880.
    • (2007) Anaesth Intensive Care , vol.35 , pp. 874-880
    • Sharma, B.1    Sharma, M.2    Majumder, M.3
  • 11
    • 0021368862 scopus 로고
    • Thrombocytopenia induced by pulmonary artery flotation catheters: a prospective study
    • Vicente Rull J.R., Loza Aguirre J., de la Puerta E., et al. Thrombocytopenia induced by pulmonary artery flotation catheters: a prospective study. Intensive Care Med 1984, 10:29-31.
    • (1984) Intensive Care Med , vol.10 , pp. 29-31
    • Vicente Rull, J.R.1    Loza Aguirre, J.2    de la Puerta, E.3
  • 12
    • 0032126712 scopus 로고    scopus 로고
    • Association of thrombocytopenia with the use of intra-aortic balloon pumps
    • Vonderheide R.H., Thadhani R., Kuter D.J. Association of thrombocytopenia with the use of intra-aortic balloon pumps. Am J Med 1998, 105:27-32.
    • (1998) Am J Med , vol.105 , pp. 27-32
    • Vonderheide, R.H.1    Thadhani, R.2    Kuter, D.J.3
  • 13
    • 0033916887 scopus 로고    scopus 로고
    • Thrombocytopenia and prognosis in intensive care
    • Vanderschueren S., De Weerdt A., Malbrain M., et al. Thrombocytopenia and prognosis in intensive care. Crit Care Med 2000, 28:1871-1876.
    • (2000) Crit Care Med , vol.28 , pp. 1871-1876
    • Vanderschueren, S.1    De Weerdt, A.2    Malbrain, M.3
  • 14
    • 0036218976 scopus 로고    scopus 로고
    • Time course of platelet counts in critically ill patients
    • Akca S., Haji-Michael P., de Mendonca A., et al. Time course of platelet counts in critically ill patients. Crit Care Med 2002, 30:753-756.
    • (2002) Crit Care Med , vol.30 , pp. 753-756
    • Akca, S.1    Haji-Michael, P.2    de Mendonca, A.3
  • 15
    • 34250834405 scopus 로고    scopus 로고
    • Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays
    • Morerau D., Timsit J.F., Vesin A., et al. Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays. Chest 2007, 131:1735-1741.
    • (2007) Chest , vol.131 , pp. 1735-1741
    • Morerau, D.1    Timsit, J.F.2    Vesin, A.3
  • 16
    • 60849112614 scopus 로고    scopus 로고
    • Implications of thrombocytopenia and platelet course on pediatric intensive care unit outcomes
    • Krishnan J., Morrison W., Simone S., et al. Implications of thrombocytopenia and platelet course on pediatric intensive care unit outcomes. Pediatr Crit Care Med 2008, 9:502-505.
    • (2008) Pediatr Crit Care Med , vol.9 , pp. 502-505
    • Krishnan, J.1    Morrison, W.2    Simone, S.3
  • 17
    • 79951589486 scopus 로고    scopus 로고
    • Refractory postinjury thrombocytopenia is associated with multiple organ failure and adverse outcomes
    • Nydam T.L., Kashuk J.L., Moore E.E., et al. Refractory postinjury thrombocytopenia is associated with multiple organ failure and adverse outcomes. J Trauma 2011, 70:401-406.
    • (2011) J Trauma , vol.70 , pp. 401-406
    • Nydam, T.L.1    Kashuk, J.L.2    Moore, E.E.3
  • 18
    • 4444286321 scopus 로고    scopus 로고
    • Risk factors of mortality in critically ill patients with thrombocytopenia
    • Masrouki S., Mebazaa M.S., Mestiri T., et al. Risk factors of mortality in critically ill patients with thrombocytopenia. Ann Fr Anesth Reanim 2004, 23:783-787.
    • (2004) Ann Fr Anesth Reanim , vol.23 , pp. 783-787
    • Masrouki, S.1    Mebazaa, M.S.2    Mestiri, T.3
  • 19
    • 77950021807 scopus 로고    scopus 로고
    • Thrombocytopenia and outcome in critically ill patients with bloodstream infection
    • Vandijck D.M., Blot S.I., De Waele J.J., et al. Thrombocytopenia and outcome in critically ill patients with bloodstream infection. Heart Lung 2010, 39:21-26.
    • (2010) Heart Lung , vol.39 , pp. 21-26
    • Vandijck, D.M.1    Blot, S.I.2    De Waele, J.J.3
  • 20
    • 80455125842 scopus 로고    scopus 로고
    • Analysis of significant decrease in platelet count and thrombocytopenia, graded according to NCI-CTC, as prognostic risk markers for mortality and morbidity
    • Olmez I., Zafar M., Shahid M., et al. Analysis of significant decrease in platelet count and thrombocytopenia, graded according to NCI-CTC, as prognostic risk markers for mortality and morbidity. J Pediatr Hematol Oncol 2011, 33:585-588.
    • (2011) J Pediatr Hematol Oncol , vol.33 , pp. 585-588
    • Olmez, I.1    Zafar, M.2    Shahid, M.3
  • 21
    • 79751534629 scopus 로고    scopus 로고
    • Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study
    • Von Lindern J.S., van den Bruele T., Lopriore E., et al. Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study. BMC Pediatr 2011, 11:16.
    • (2011) BMC Pediatr , vol.11 , pp. 16
    • Von Lindern, J.S.1    van den Bruele, T.2    Lopriore, E.3
  • 22
    • 2942726675 scopus 로고    scopus 로고
    • Platelet-endothelial interactions: sepsis, HIT, and antiphospholipid syndrome
    • Warkentin T.E., Aird W.C., Rand J.H. Platelet-endothelial interactions: sepsis, HIT, and antiphospholipid syndrome. Hematology Am Soc Hematol Educ Program 2003, 2003:497-519.
    • (2003) Hematology Am Soc Hematol Educ Program , vol.2003 , pp. 497-519
    • Warkentin, T.E.1    Aird, W.C.2    Rand, J.H.3
  • 23
    • 79952219926 scopus 로고    scopus 로고
    • Beyond thrombosis: the versatile platelet in critical illness
    • Katz J.N., Kolappa K.P., Becker R.C. Beyond thrombosis: the versatile platelet in critical illness. Chest 2011, 139:658-668.
    • (2011) Chest , vol.139 , pp. 658-668
    • Katz, J.N.1    Kolappa, K.P.2    Becker, R.C.3
  • 24
    • 17144369137 scopus 로고    scopus 로고
    • Mechanistic basis of heparin-induced thrombocytopenia
    • Poncz M. Mechanistic basis of heparin-induced thrombocytopenia. Semin Thorac Cardiovasc Surg 2005, 17:73-79.
    • (2005) Semin Thorac Cardiovasc Surg , vol.17 , pp. 73-79
    • Poncz, M.1
  • 25
    • 82755187620 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in critically ill patients
    • Warkentin T.E. Heparin-induced thrombocytopenia in critically ill patients. Crit Care Clin 2011, 27:805-823.
    • (2011) Crit Care Clin , vol.27 , pp. 805-823
    • Warkentin, T.E.1
  • 26
    • 34247891643 scopus 로고    scopus 로고
    • Endothelial cell damage in heparin-induced thrombocytopenia
    • Davidson S.J., Wadham P., Rogers L., et al. Endothelial cell damage in heparin-induced thrombocytopenia. Blood Coagul Fibrinolysis 2007, 18:317-320.
    • (2007) Blood Coagul Fibrinolysis , vol.18 , pp. 317-320
    • Davidson, S.J.1    Wadham, P.2    Rogers, L.3
  • 27
    • 22144446420 scopus 로고    scopus 로고
    • Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis: a retrospective analysis of 408 patients
    • Greinacher A., Farner B., Kroll H., et al. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis: a retrospective analysis of 408 patients. Throb Haemost 2005, 94:132-135.
    • (2005) Throb Haemost , vol.94 , pp. 132-135
    • Greinacher, A.1    Farner, B.2    Kroll, H.3
  • 28
    • 34247127070 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in intensive care patients
    • Selleng K., Warkentin T.E., Greinacher A. Heparin-induced thrombocytopenia in intensive care patients. Crit Care Med 2007, 35:1165-1176.
    • (2007) Crit Care Med , vol.35 , pp. 1165-1176
    • Selleng, K.1    Warkentin, T.E.2    Greinacher, A.3
  • 29
    • 45949103154 scopus 로고    scopus 로고
    • Treatment and prevention of heparin-induced thrombocytopenia; 8th ed: American College of Chest Physicians evidence-based clinical practice guidelines
    • American College of Chest Physicians
    • Warkentin T.E., Greinacher A., Koster A., et al. Treatment and prevention of heparin-induced thrombocytopenia; 8th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2008, 133(6 Suppl):340S-380S. American College of Chest Physicians.
    • (2008) Chest , vol.133 , Issue.6 SUPPL.
    • Warkentin, T.E.1    Greinacher, A.2    Koster, A.3
  • 30
    • 79960260452 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: analysis of risk factors in medical inpatients
    • Kato S., Takahashi K., Ayabe K., et al. Heparin-induced thrombocytopenia: analysis of risk factors in medical inpatients. Br J Haematol 2011, 154:373-377.
    • (2011) Br J Haematol , vol.154 , pp. 373-377
    • Kato, S.1    Takahashi, K.2    Ayabe, K.3
  • 31
    • 33644971524 scopus 로고    scopus 로고
    • Evaluation of pretest score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings
    • Lo G.K., Juhl D., Warkentin T.E., et al. Evaluation of pretest score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb haemost 2006, 4:759-765.
    • (2006) J Thromb haemost , vol.4 , pp. 759-765
    • Lo, G.K.1    Juhl, D.2    Warkentin, T.E.3
  • 32
    • 77953286757 scopus 로고    scopus 로고
    • The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients
    • The Canadian Critical Care Trials Group
    • Crowther M.A., Cook D.J., Albert M., et al. The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients. J Crit Care 2010, 25:287-293. The Canadian Critical Care Trials Group.
    • (2010) J Crit Care , vol.25 , pp. 287-293
    • Crowther, M.A.1    Cook, D.J.2    Albert, M.3
  • 33
    • 78650000811 scopus 로고    scopus 로고
    • The HIT Expert Probability (HEP) Score: a novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion
    • Cuker A., Arepally G., Crowther M.A., et al. The HIT Expert Probability (HEP) Score: a novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion. J Thromb Haemost 2010, 8:2642-2650.
    • (2010) J Thromb Haemost , vol.8 , pp. 2642-2650
    • Cuker, A.1    Arepally, G.2    Crowther, M.A.3
  • 34
    • 0038689143 scopus 로고    scopus 로고
    • Frequency of heparin-induced thrombocytopenia in critical care patients
    • Verma A.K., Levine M., Shalansky S.J., et al. Frequency of heparin-induced thrombocytopenia in critical care patients. Pharmacotherapy 2003, 23:745-753.
    • (2003) Pharmacotherapy , vol.23 , pp. 745-753
    • Verma, A.K.1    Levine, M.2    Shalansky, S.J.3
  • 35
    • 33645723747 scopus 로고    scopus 로고
    • Incidence and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA class in 755 consecutive patient samples referred for diagnostic testing for heparin-induced thrombocytopenia
    • Juhl D., Eichler P., Lubenow N., et al. Incidence and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA class in 755 consecutive patient samples referred for diagnostic testing for heparin-induced thrombocytopenia. Eur J Haematol 2006, 76:420-426.
    • (2006) Eur J Haematol , vol.76 , pp. 420-426
    • Juhl, D.1    Eichler, P.2    Lubenow, N.3
  • 36
    • 34447617364 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes
    • Greinacher A., Juhl D., Strobel U., et al. Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes. J Thromb Haemost 2007, 5:1666-1673.
    • (2007) J Thromb Haemost , vol.5 , pp. 1666-1673
    • Greinacher, A.1    Juhl, D.2    Strobel, U.3
  • 37
    • 45949112509 scopus 로고    scopus 로고
    • Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays
    • Warkentin T.E., Sheppard J.L., Moore J.C., et al. Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays. J Thormb Haemost 2008, 6:1304-1312.
    • (2008) J Thormb Haemost , vol.6 , pp. 1304-1312
    • Warkentin, T.E.1    Sheppard, J.L.2    Moore, J.C.3
  • 38
    • 79952502409 scopus 로고    scopus 로고
    • A clinical-laboratory algorithm incorporating optical density value to predict heparin-induced thrombocytopenia
    • Ruf K.M., Bensadoun E.S., Davis G.A., et al. A clinical-laboratory algorithm incorporating optical density value to predict heparin-induced thrombocytopenia. Thromb Haemost 2011, 105:553-559.
    • (2011) Thromb Haemost , vol.105 , pp. 553-559
    • Ruf, K.M.1    Bensadoun, E.S.2    Davis, G.A.3
  • 39
    • 84455208206 scopus 로고    scopus 로고
    • Thrombosis in suspected heparin-induced thrombocytopenia occurs more often with high antibody levels
    • Baroletti S., Hurwitz S., Conti N.A., et al. Thrombosis in suspected heparin-induced thrombocytopenia occurs more often with high antibody levels. Am J Med 2012, 125:44-49.
    • (2012) Am J Med , vol.125 , pp. 44-49
    • Baroletti, S.1    Hurwitz, S.2    Conti, N.A.3
  • 40
    • 74249094682 scopus 로고    scopus 로고
    • Effectiveness of a new immunoassay for the diagnosis of heparin-induced thrombocytopenia and improved specificity when detecting IgG antibodies
    • Pouplard C., Leroux D., Regina S., et al. Effectiveness of a new immunoassay for the diagnosis of heparin-induced thrombocytopenia and improved specificity when detecting IgG antibodies. Thromb Haemost 2010, 103:145-150.
    • (2010) Thromb Haemost , vol.103 , pp. 145-150
    • Pouplard, C.1    Leroux, D.2    Regina, S.3
  • 41
    • 79952993615 scopus 로고    scopus 로고
    • Performance characteristics of two commercially available IgG-specific immunoassays in the assessment of heparin-induced thrombocytopenia (HIT)
    • Bakchoul T., Giptner A., Bein G., et al. Performance characteristics of two commercially available IgG-specific immunoassays in the assessment of heparin-induced thrombocytopenia (HIT). Thromb Res 2011, 127:345-348.
    • (2011) Thromb Res , vol.127 , pp. 345-348
    • Bakchoul, T.1    Giptner, A.2    Bein, G.3
  • 42
    • 84857746149 scopus 로고    scopus 로고
    • Validation of whole blood impedance aggregometry as a new diagnostic tool for HIT. Results of a large Australian study
    • ASTH Clinical Trials Group
    • Morel-Kopp M.C., Tan C.W., Brighton T.A., et al. Validation of whole blood impedance aggregometry as a new diagnostic tool for HIT. Results of a large Australian study. Thromb Haemost 2012, 107(3):575-583. ASTH Clinical Trials Group.
    • (2012) Thromb Haemost , vol.107 , Issue.3 , pp. 575-583
    • Morel-Kopp, M.C.1    Tan, C.W.2    Brighton, T.A.3
  • 43
    • 83155167576 scopus 로고    scopus 로고
    • A colorimetric, metabolic dye reduction assay detects highly activated platelets: application in the diagnosis of heparin-induced thrombocytopenia
    • Prechel M.M., Escalante V., Drenth A.F., et al. A colorimetric, metabolic dye reduction assay detects highly activated platelets: application in the diagnosis of heparin-induced thrombocytopenia. Platelets 2012, 23:69-80.
    • (2012) Platelets , vol.23 , pp. 69-80
    • Prechel, M.M.1    Escalante, V.2    Drenth, A.F.3
  • 44
    • 77955119891 scopus 로고    scopus 로고
    • Agents for the treatment of heparin-induced thrombocytopenia
    • Warkentin T.E. Agents for the treatment of heparin-induced thrombocytopenia. Hematol Oncol Clin North Am 2010, 24:755-775.
    • (2010) Hematol Oncol Clin North Am , vol.24 , pp. 755-775
    • Warkentin, T.E.1
  • 45
    • 55249103594 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: diagnosis and management
    • Hassell K. Heparin-induced thrombocytopenia: diagnosis and management. Thromb Res 2008, 123(Suppl 1):S16-S21.
    • (2008) Thromb Res , vol.123 , Issue.SUPPL. 1
    • Hassell, K.1
  • 46
    • 82755189078 scopus 로고    scopus 로고
    • Fondaparinux treatment of acute heparin-induced thrombocytopenia confirmed by the serotonin-release assay; a 30-month, 16-patient case series
    • Warkentin T.E., Pai M., Sheppard J.L., et al. Fondaparinux treatment of acute heparin-induced thrombocytopenia confirmed by the serotonin-release assay; a 30-month, 16-patient case series. J Thromb Haemost 2011, 9:2389-2396.
    • (2011) J Thromb Haemost , vol.9 , pp. 2389-2396
    • Warkentin, T.E.1    Pai, M.2    Sheppard, J.L.3
  • 47
    • 35548974427 scopus 로고    scopus 로고
    • Strategies for the management of suspected heparin-induced thrombocytopenia: a cost-effectiveness analysis
    • Patrick A.R., Winkelmayer W.C., Avorn J., et al. Strategies for the management of suspected heparin-induced thrombocytopenia: a cost-effectiveness analysis. Pharmacoeconomics 2007, 25:949-961.
    • (2007) Pharmacoeconomics , vol.25 , pp. 949-961
    • Patrick, A.R.1    Winkelmayer, W.C.2    Avorn, J.3
  • 48
    • 51649129542 scopus 로고    scopus 로고
    • The financial impact of heparin-induced thrombocytopenia
    • Smythe M.A., Koerber J.M., Fitzgerald M., et al. The financial impact of heparin-induced thrombocytopenia. Chest 2008, 134:568-573.
    • (2008) Chest , vol.134 , pp. 568-573
    • Smythe, M.A.1    Koerber, J.M.2    Fitzgerald, M.3
  • 49
    • 69749095678 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: an estimate of the average cost in the hospital setting in France
    • Elalamy I., Le Gal G., Nachit-Ouinekh F., et al. Heparin-induced thrombocytopenia: an estimate of the average cost in the hospital setting in France. Clin Appl Thromb Hemost 2009, 15:428-434.
    • (2009) Clin Appl Thromb Hemost , vol.15 , pp. 428-434
    • Elalamy, I.1    Le Gal, G.2    Nachit-Ouinekh, F.3
  • 50
    • 79956123193 scopus 로고    scopus 로고
    • The direct medical costs associated with suspected heparin-induced thrombocytopenia
    • Nanwa N., Mittmann N., Knowles S., et al. The direct medical costs associated with suspected heparin-induced thrombocytopenia. Pharmacoeconomics 2011, 29:511-520.
    • (2011) Pharmacoeconomics , vol.29 , pp. 511-520
    • Nanwa, N.1    Mittmann, N.2    Knowles, S.3
  • 51
    • 37149017816 scopus 로고    scopus 로고
    • Other immune thrombocytopenias
    • Liebman H. Other immune thrombocytopenias. Semin Hematol 2007, 44(4 Suppl 5):S24-S34.
    • (2007) Semin Hematol , vol.44 , Issue.4 SUPPL. 5
    • Liebman, H.1
  • 52
    • 60549085053 scopus 로고    scopus 로고
    • Pathobiology of secondary immune thrombocytopenia
    • Cines D.B., Liebman H., Stasi R. Pathobiology of secondary immune thrombocytopenia. Semin Hematol 2009, 46(1 Suppl 2):S2-S14.
    • (2009) Semin Hematol , vol.46 , Issue.1 SUPPL. 2
    • Cines, D.B.1    Liebman, H.2    Stasi, R.3
  • 53
    • 77749273827 scopus 로고    scopus 로고
    • Thrombocytopenia after abciximab use results from different mechanisms
    • Lajus S., Clofent-Sanchez G., Jais C., et al. Thrombocytopenia after abciximab use results from different mechanisms. Thromb Haemost 2010, 103:651-661.
    • (2010) Thromb Haemost , vol.103 , pp. 651-661
    • Lajus, S.1    Clofent-Sanchez, G.2    Jais, C.3
  • 54
    • 6344286003 scopus 로고    scopus 로고
    • Delayed immunologic thrombocytopenia induced by abciximab
    • Nurden P., Clofent-Sanchez G., Jais C., et al. Delayed immunologic thrombocytopenia induced by abciximab. Thromb Haemost 2004, 92:820-828.
    • (2004) Thromb Haemost , vol.92 , pp. 820-828
    • Nurden, P.1    Clofent-Sanchez, G.2    Jais, C.3
  • 56
    • 33750738083 scopus 로고    scopus 로고
    • Post-transfusion purpura: a challenging diagnosis
    • Shtalrid M., Shvidel L., Vorst E., et al. Post-transfusion purpura: a challenging diagnosis. Isr Med Assoc J 2006, 8:672-674.
    • (2006) Isr Med Assoc J , vol.8 , pp. 672-674
    • Shtalrid, M.1    Shvidel, L.2    Vorst, E.3
  • 57
    • 3042595830 scopus 로고    scopus 로고
    • Efficacy of HPA-1a (PLA1)-negative platelets in a patient with post-transfusion purpura
    • Loren A.W., Abrams C.S. Efficacy of HPA-1a (PLA1)-negative platelets in a patient with post-transfusion purpura. Am J Hematol 2004, 76:2258-2262.
    • (2004) Am J Hematol , vol.76 , pp. 2258-2262
    • Loren, A.W.1    Abrams, C.S.2
  • 58
    • 0034324768 scopus 로고    scopus 로고
    • Very low platelet counts in post-transfusion purpura falsely diagnosed as heparin-induced thrombocytopenia: report of four cases and review of literature
    • Lubenow N., Eichler P., Albrecht D., et al. Very low platelet counts in post-transfusion purpura falsely diagnosed as heparin-induced thrombocytopenia: report of four cases and review of literature. Thromb Res 2000, 100:115-125.
    • (2000) Thromb Res , vol.100 , pp. 115-125
    • Lubenow, N.1    Eichler, P.2    Albrecht, D.3
  • 59
    • 77949480545 scopus 로고    scopus 로고
    • Thrombocytopenia and thrombosis in disseminated intravascular coagulation (DIC)
    • Kitchens C.S. Thrombocytopenia and thrombosis in disseminated intravascular coagulation (DIC). Hematology Am Soc Hematol Educ Program 2009, 240-246.
    • (2009) Hematology Am Soc Hematol Educ Program , pp. 240-246
    • Kitchens, C.S.1
  • 60
    • 14044270036 scopus 로고    scopus 로고
    • Thrombocytopenia: one of the markers of disseminated intravascular coagulation
    • Ten Cate H. Thrombocytopenia: one of the markers of disseminated intravascular coagulation. Pathophysiol Haemost Thromb 2003, 33:413-416.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , pp. 413-416
    • Ten Cate, H.1
  • 61
    • 84856998772 scopus 로고    scopus 로고
    • Thrombotic microangiopathies, thrombotic thrombocytopenic purpura, and ADAMTS-13
    • Chapman K., Seldon M., Richards R. Thrombotic microangiopathies, thrombotic thrombocytopenic purpura, and ADAMTS-13. Semin Thromb Hemost 2012, 38:47-54.
    • (2012) Semin Thromb Hemost , vol.38 , pp. 47-54
    • Chapman, K.1    Seldon, M.2    Richards, R.3
  • 62
    • 0034824687 scopus 로고    scopus 로고
    • Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome
    • Medina P.J., Sipols, George J.N. Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Curr Opin Hematol 2001, 8:286-293.
    • (2001) Curr Opin Hematol , vol.8 , pp. 286-293
    • Medina, P.J.1    Sipols2    George, J.N.3
  • 63
    • 63049106291 scopus 로고    scopus 로고
    • Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008)
    • Zakarija A., Kwaan H.C., Moake J.L., et al. Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008). Kidney Int Suppl 2009, 112:S20-S24.
    • (2009) Kidney Int Suppl , vol.112
    • Zakarija, A.1    Kwaan, H.C.2    Moake, J.L.3
  • 64
    • 84857440257 scopus 로고    scopus 로고
    • Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura
    • [Epub ahead of print]
    • Coppo P., Veyradier A. Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura. Presse Med 2012, [Epub ahead of print].
    • (2012) Presse Med
    • Coppo, P.1    Veyradier, A.2
  • 65
    • 84858705735 scopus 로고    scopus 로고
    • Thrombotic microangiopathy: Current knowledge and outcomes with plasma exchange
    • [Epub ahead of print]
    • Clark W.F. Thrombotic microangiopathy: Current knowledge and outcomes with plasma exchange. Semin Dial 2012, [Epub ahead of print].
    • (2012) Semin Dial
    • Clark, W.F.1
  • 66
    • 84856505271 scopus 로고    scopus 로고
    • Treatment of enterohemorrhagic E. coli (EHEC) infection and hemolytic uremic syndrome (HUS)
    • Goldwater P.N., Bettelheim K.A. Treatment of enterohemorrhagic E. coli (EHEC) infection and hemolytic uremic syndrome (HUS). BMC Med 2012, 10:12.
    • (2012) BMC Med , vol.10 , pp. 12
    • Goldwater, P.N.1    Bettelheim, K.A.2
  • 67
    • 81255130615 scopus 로고    scopus 로고
    • Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome
    • Ohanian M., Cable C., Halka K. Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome. Clin Pharmacol 2011, 3:5-12.
    • (2011) Clin Pharmacol , vol.3 , pp. 5-12
    • Ohanian, M.1    Cable, C.2    Halka, K.3
  • 68
    • 34247102267 scopus 로고    scopus 로고
    • Current diagnosis of inherited bone marrow failure syndromes
    • Tamary H., Alter B.P. Current diagnosis of inherited bone marrow failure syndromes. Pediatr Hematol Oncol 2007, 24:87-99.
    • (2007) Pediatr Hematol Oncol , vol.24 , pp. 87-99
    • Tamary, H.1    Alter, B.P.2
  • 69
    • 41149087836 scopus 로고    scopus 로고
    • Inherited aplastic anaemias/bone marrow failure syndromes
    • Dokal I., Vulliamy T. Inherited aplastic anaemias/bone marrow failure syndromes. Blood Rev 2008, 22:141-153.
    • (2008) Blood Rev , vol.22 , pp. 141-153
    • Dokal, I.1    Vulliamy, T.2
  • 70
    • 77954348335 scopus 로고    scopus 로고
    • Frequency and natural history of inherited bone marrow failure syndromes: the Israeli Inherited Bone Marrow Failure registry
    • Tamary H., Nishri D., Yacobovich J., et al. Frequency and natural history of inherited bone marrow failure syndromes: the Israeli Inherited Bone Marrow Failure registry. Haematologica 2010, 95:1300-1307.
    • (2010) Haematologica , vol.95 , pp. 1300-1307
    • Tamary, H.1    Nishri, D.2    Yacobovich, J.3
  • 71
    • 4344700331 scopus 로고    scopus 로고
    • Acquired aplastic anemia
    • Keohane E.M. Acquired aplastic anemia. Clin Lab Sci 2004, 17:165-171.
    • (2004) Clin Lab Sci , vol.17 , pp. 165-171
    • Keohane, E.M.1
  • 72
    • 33846413513 scopus 로고    scopus 로고
    • An update on the management of severe idiopathic aplastic anaemia in children
    • Davies J.K., Guinan E.C. An update on the management of severe idiopathic aplastic anaemia in children. Br J Haematol 2007, 136:549-564.
    • (2007) Br J Haematol , vol.136 , pp. 549-564
    • Davies, J.K.1    Guinan, E.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.