Integrated strategies needed to prevent iron deficiency and to promote early child development

Journal of Trace Elements in Medicine and Biology

Volumn 26, Issue 2-3, 2012, Pages 120-123

  Black, Maureen M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Caregiving; Infant iron deficiency; Maternal depression; Maternal iron deficiency; Mother child interaction

Indexed keywords

DOPAMINE; FOLIC ACID; IRON; ZINC;

ARTICLE; BRAIN FUNCTION; CHILD CARE; CHILD DEVELOPMENT; CHILD HEALTH CARE; COGNITION; DISEASE ASSOCIATION; DOPAMINE METABOLISM; DRUG EFFICACY; EMOTIONALITY; HIPPOCAMPUS; HOME CARE; HUMAN; INFANT NUTRITION; IRON DEFICIENCY; IRON DEFICIENCY ANEMIA; IRON THERAPY; LOWEST INCOME COUNTRY; MIDDLE INCOME COUNTRY; MOTHER CHILD RELATION; MYELINATION; NEUROANATOMY; NUTRITIONAL DISORDER; NUTRITIONAL REQUIREMENT; NUTRITIONAL STATUS; PATIENT CARE PLANNING; PHYSIOLOGY; PREGNANT WOMAN; PREMATURITY; PRENATAL PERIOD; PRIORITY JOURNAL; PUERPERAL DEPRESSION; SOCIAL ASPECT; SOCIOECONOMICS;

ANEMIA, IRON-DEFICIENCY; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; DEPRESSIVE DISORDER; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; IRON; MALE; MOTHER-CHILD RELATIONS; PREGNANCY;

EID: 84862514387     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2012.04.020     Document Type: Article

References (44)

1. McLean E., Cogswell M., Egli I., Wojdyla D., de Benoist B. Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005. Public Health Nutr 2009, 12(4):444-454.
2. Stoltzfus R.J. Iron interventions for women and children in low-income countries. J Nutr 2011, 141(4):756S-762S.
3. Mei Z., Cogswell M., Looker A., Pfeiffer C., Cusick S., Lacher D., et al. Assessment of iron status in US pregnant women from the National Health and Nutrition Examination Survey (NHANES), 1999-2006. Am J Clin Nutr 2011, 93(6):1312-1320.
4. Brotanek J.M., Gosz J., Weitzman M., Flores G. Secular trends in the prevalence of iron deficiency among US toddlers, 1976-2002. Arch Pediatr Adolesc Med 2008, 162(4):374-381.
5. Kalaivani K. Prevalence & consequences of anaemia in pregnancy. Indian J Med Res 2009, 130(5):627-633.
6. International Institute for Population Sciences and Macro International National family health survey, 2005-2006 2007, International Institute for Population Sciences, Mumbai, India.
7. Baker R.D., Greer F.R. Clinical report - diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics 2010, 126:1040-1050.
8. Amin S.B., Orlando M., Eddins A., MacDonald M., Monczynski C., Wang H. In utero iron status and auditory neural maturation in premature infants as evaluated by auditory brainstem response. J Pediatr 2010, 156:377-381.
9. Tamura T., Goldenberg R.L., Hou J., Johnson K.E., Cliver S.P., Ramey S.L., et al. Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age. J Pediatr 2002, 140:165-170.
10. Thompson R.A., Nelson C.A. Developmental science and the media: early brain development. Am Psychol 2001, 56(1):5-15.
11. Iannotti L.L., Tielsch J.M., Black M.M., Black R.E. Iron supplementation in early childhood: health benefits and risks. Am J Clin Nutr 2006, 84:1261-1276.
12. McCann J.C., Ames B.N. An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral functioning. Am J Clin Nutr 2007, 85:931-945.
13. Georgieff M.K. Long-term brain and behavioral consequences of early iron deficiency. Nutr Rev 2011, 69:S43-S48.
14. Peirano P.D., Algarin C.R., Chamorro R., Reyes S., Garrido M.I., Duran S., et al. Sleep and neurofunctions throughout child development: lasting effects of early iron deficiency. Pediatr Gastroenterol Nutr 2009, 48(Suppl. 1):S8-S15.
15. Beard J.L. Why iron deficiency is important in infant development. J Nutr 2008, 138:2534-2536.
16. Perez E.M., Hendricks M.K., Beard J.L. Mother-infant interactions and infant development are altered by maternal iron deficiency anemia. J Nutr 2005, 135:850-855.
17. Papas M.A., Hurley K.M., Quigg A.M., Oberlander S.E., Black M.M. Low-income, African American adolescent mothers and their toddlers exhibit similar dietary variety patterns. J Nutr Educ Behav 2009, 41:87-94.
18. Murray-Kolb L.E. Iron status and neuropsychological consequences in women of reproductive age: what do we know and where are we headed?. J Nutr 2011, 141(4):747S-755S.
19. Corwin E.J., Murray-Kolb L.E., Beard J.L. Low hemoglobin level is a risk factor for postpartum depression. J Nutr 2003, 133(12):4139-4142.
20. Beard J.L., Hendricks M.K., Perez E.M., Murray-Kolb L.E., Berg A., Vernon-Feagans L., et al. Maternal iron deficiency anemia affects postpartum emotions and cognition. J Nutr 2005, 135(2):267-272.
21. Murray-Kolb L.E., Beard J.L. Iron deficiency and child and maternal health. Am J Clin Nutr 2009, 89(3):946S-950S.
22. Perez E.M., Hendricks M.K., Beard J.L., Murray-Kolb L.E., Berg A., Tomlinson M., et al. Mother-infant interactions and infant development are altered by maternal iron deficiency anemia. J Nutr 2005, 135(4):850-855.
23. DeMayer E., Tegman A. Prevalence of anaemia in the world. World Health Organ Q 1998, 38:302-316.
24. Beard J.L., Connor J.R. Iron status and neural functioning. Annu Rev Nutr 2003, 23:41-58.
25. Van Ijzendoorn M., Bakermans-Kranenburg M., Mesman J. Dopamine system genes associated with parenting in the context of daily hassles. Genes Brain Behav 2008, 7(June (4)):403-410.
26. Prince M., Patel V., Saxena S., Maj M., Maselko J., Phillips M.R., et al. No health without mental health. Lancet 2007, 370(9590):859-877.
27. World Health Organization. World report on disabilities. WHO library cataloguing-in-publication data. Available at <>; 2011 [assessed 13.10.11]. http://www.who.int/disabilities/world_report/2011/report.pdf.
28. Wachs T., Black M., Engle P. Maternal depression: a global threat to children's health, development, and behavior and to human rights. Child Dev Perspect 2009, 3:51-59.
29. Lovejoy M.C., Graczyk P.A., O'Hare E., Neuman G. Maternal depression and parenting behavior: a meta-analytic review. Clin Psychol Rev 2000, 20(5):561-592.
30. World Health Organization Mental health atlas 2005, Department of Mental Health and Substance Abuse, Geneva, Switzerland.
31. Moussavi S., Chatterji S., Verdes E., Tandon A., Patel V., Ustun B. Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet 2007, 370(9590):851-858.
32. Pincus H.A., Pettit A.R. The societal costs of chronic major depression. J Clin Psychiatry 2001, 62(Suppl. 6):5-9.
33. Surkan P.J., Kennedy C.E., Hurley K.M., Black M.M. Maternal depression and early childhood growth in developing countries: systematic review and meta-analysis. Bull World Health Organ 2011, 89(8):608-615.
34. Black M.M., Baqui A.H., Zaman K., McNary S.W., Le K., Arifeen S.E., et al. Depressive symptoms among rural Bangladeshi mothers: implications for infant development. J Child Psychol Psychiatry 2007, 48(8):764-772.
35. Stoltzfus R.J., Dreyfuss M.L. Guidelines for the use of iron supplements to prevent and treat iron deficiency anemia 1998, ILSI Press, Washington, DC.
36. Black M.M., Quigg A.M., Hurley K.M., Pepper M.R. Iron deficiency and iron-deficiency anemia in the first two years of life: strategies to prevent loss of developmental potential. Nutr Rev 2011, 69:S64-S70.
37. Szajewska H., Ruszczynski M., Chmielewska A. Effects of iron supplementation in nonanemic pregnant women, infants, and young children on the mental performance and psychomotor development of children: a systematic review of randomized controlled trials. Am J Clin Nutr 2010, 91(6):1684-1690.
38. Logan S., Martins S., Gilbert R. Iron therapy for improving psychomotor development and cognitive function in children under the age of three with iron deficiency anaemia. Cochrane Database Syst Rev 2001, (2):CD001444.
39. Pongcharoen T., DiGirolamo A.M., Ramakrishnan U., Winichagoon P., Flores R., Martorell R. Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study. Am J Clin Nutr 2011, 93(3):636-643.
40. Christian P., Morgan M.E., Murray-Kolb L., LeClerq S.C., Khatry S.K., Schaefer B., et al. Preschool iron-folic acid and zinc supplementation in children exposed to iron-folic acid in utero confers no added cognitive benefit in early school-age. J Nutr 2011, 141(11):2042-2048.
41. Christian P., Murray-Kolb L.E., Khatry S.K., Katz J., Schaefer B.A., Cole P.M., et al. Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal. JAMA 2010, 304(24):2716-2723.
42. Chang S., Wang L., Wang Y., Brouwer I.D., Kok F.J., Lozoff B., et al. Iron-deficiency anemia in infancy and social emotional development in preschool-aged Chinese children. Pediatrics 2011, 127(4):e927-e933.
43. Lozoff B., Smith J.B., Clark K.M., Perales C.G., Rivera F., Castillo M. Home intervention improves cognitive and social-emotional scores in iron-deficient anemic infants. Pediatrics 2010, 126(4):e884-e894.
44. Gardner J.M., Powell C.A., Baker-Henningham H., Walker S.P., Cole T.J., Grantham-McGregor S.M. Zinc supplementation and psychosocial stimulation: effects on the development of undernourished Jamaican children. Am J Clin Nutr 2005, 82(2):399-405.