Genomic analysis of between-cow variation in dermal fibroblast response to lipopolysaccharide

Journal of Dairy Science

Volumn 95, Issue 7, 2012, Pages 3852-3864

  Kandasamy, S ^a   Kerr, D E ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Dairy cow; Interleukin 8; Toll like receptor pathway

Indexed keywords

ACTIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; CATTLE; CELL CULTURE; DNA MICROARRAY; DRUG EFFECT; FEMALE; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; GENETICS; IMMUNOLOGY; METABOLISM; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACTINS; ANIMALS; CATTLE; CELLS, CULTURED; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENETIC VARIATION; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 4;

EID: 84862509088     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2011-5251     Document Type: Article

References (44)

1. Arend W.P., Palmer G., Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol. Rev. 2008, 223:20-38.
2. Avniel S., Arik Z., Maly A., Sagie A., Basst H.B., Yahana M.D., Weiss I.D., Pal B., Wald O., Ad-El D., Fujii N., Arenzana-Seisdedos F., Jung S., Galun E., Gur E., Peled A. Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns. J. Invest. Dermatol. 2006, 126:468-476.
3. Bannerman D.D. Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows. J. Anim. Sci. 2009, 87:10-25.
4. Bengtsson H., Simpson K., Bullard J., Hansen K. Aroma.affymetrix: A generic framework in R for analyzing small to very large Affymetrix data sets in bounded memory. Tech Report #745 2008, Department of Statistics, University of California, Berkeley.
5. Berry D.P., Bermingham M.L., Good M., More S.J. Genetics of animal health and disease in cattle. Ir. Vet. J. 2011, 64:5.
6. Bleul C.C., Fuhlbrigge R.C., Casasnovas J.M., Aiuti A., Springer T.A. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J. Exp. Med. 1996, 184:1101-1109.
7. Bolstad B.M., Irizarry R.A., Astrand M., Speed T.P. A comparison of normalization methods for high-density oligonucleotide array data based on variance and bias. Bioinformatics 2003, 19:185.
8. Boulanger D., Bureau F., Melotte D., Mainil J., Lekeux P. Increased nuclear factor κ-B activity in milk cells of mastitis-affected cows. J. Dairy Sci. 2003, 86:1259-1267.
9. Burvenich C., Bannerman D.D., Lippolis J.D., Peelman L., Nonnecke B.J., Kehrli M.E., Paape M.J. Cumulative physiological events influence the inflammatory response of the bovine udder to Escherichia coli infections during the transition period. J. Dairy Sci. 2007, 90(E. Suppl.):E39-E54.
10. Burvenich C., Merris V.V., Mehrzad J., Diez-Fraile A., Duchateau L. Severity of E. coli mastitis is mainly determined by cow factors. Vet. Res. 2003, 34:521-564.
11. Buwitt-Beckmann U., Heine H., Wiesmuller K.H., Jung G., Brock R., Akira S., Ulmer A.J. Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur. J. Immunol. 2005, 35:282-289.
12. Davidson D.J., Currie A.J., Bowdish D.M., Brown K.L., Rosenberger C.M., Ma R.C., Bylund J., Campsall P.A., Puel A., Picard C., Casanova J.L., Turvey S.E., Hancock R.E., Devon R.S., Speert D.P. IRAK-4 mutation (Q293X): Rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells. J. Immunol. 2006, 177:8202-8211.
13. Detilleux J.C. Genetic factors affecting susceptibility to udder pathogens. Vet. Microbiol. 2009, 134:157-164.
14. Farhat K., Riekenberg S., Jung G., Wiesmüller K.-H., Jungi T.W., Ulmer A.J. Identification of full length bovine TLR1 and functional characterization of lipopeptide recognition by bovine TLR2/1 heterodimer. Vet. Res. 2010, 41:34.
15. Galvão K.N., Pighetti G.M., Cheong S.H., Nydam D.V., Gilbert R.O. Association between interleukin-8 receptor-α (CXCR1) polymorphism and disease incidence, production, reproduction, and survival in Holstein cows. J. Dairy Sci. 2011, 94:2083-2091.
16. Gentleman R. Bioinformatics and Computational Biology Solutions using R and Bioconductor 2005, Springer Verlag, Berlin, Germany.
17. Gentleman R.C., Carey V., Bates D., Bolstad B., Dettling M., Dudoit S., Ellis B., Gautier L., Ge Y., Gentry J. Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol. 2004, 5:R80.
18. Green B.B., Kandasamy S., Elsasser T.H., Kerr D.E. The use of dermal fibroblasts as a predictive tool of the toll-like receptor 4 response pathway and its development in Holstein heifers. J. Dairy Sci. 2011, 94:5502-5514.
19. Griesbeck-Zilch B., Osman M., Kuhn C., Schwerin M., Bruckmaier R.H., Pfaffl M.W., Hammerle-Fickinger A., Meyer H.H.D., Wellnitz O. Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle. J. Dairy Sci. 2009, 92:4621-4633.
20. Günther J., Esch K., Poschadel N., Petzl W., Zerbe H., Mitterhuemer S., Blum H., Seyfert H.M. Comparative kinetics of Escherichia coli- and Staphylococcus aureus-specific activation of key immune pathways in mammary epithelial cells demonstrates that S. aureus elicits a delayed response dominated by interleukin-6 (IL-6) but not by IL-1A or tumor necrosis factor alpha. Infect. Immun. 2011, 79:695-707.
21. Heringstad B., Klemetsdal G., Steine T. Selection responses for disease resistance in two selection experiments with Norwegian Red cows. J. Dairy Sci. 2007, 90:2419-2426.
22. Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Murakami K., Miyake Y., Matsuo T. CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease. Clin. Exp. Immunol. 2005, 141:467-474.
23. Ibeagha-Awemu E.M., Lee J.W., Ibeagha A.E., Bannerman D.D., Paape M.J., Zhao X. Bacterial lipopolysaccharide induces increased expression of toll-like receptor (TLR) 4 and downstream TLR signaling molecules in bovine mammary epithelial cells. Vet. Res. 2007, 39:11.
24. Kandasamy S., Green B.B., Benjamin A.L., Kerr D.E. Between-cow variation in dermal fibroblast response to lipopolysaccharide reflected in resolution of inflammation during Escherichia coli mastitis. J. Dairy Sci. 2011, 94:5963-5975.
25. Kawai T., Akira S. The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors. Nat. Immunol. 2010, 11:373-384.
26. Kornalijnslijper J.E., Daemen A.J., van Werven T., Niewold T.A., Rutten V.P., Noordhuizen-Stassen E.N. Bacterial growth during the early phase of infection determines the severity of experimental Escherichia coli mastitis in dairy cows. Vet. Microbiol. 2004, 101:177-186.
27. Kuhn C., Reinhardt F., Schwerin M. Marker assisted selection of heifers improved milk somatic cell count compared to selection on conventional pedigree breeding values. Arch Tierzucht. 2008, 51:23-32.
28. Lichtenauer-Kaligis E.G., Dalm V.A., Oomen S.P., Mooij D.M., van Hagen P.M., Lamberts S.W., Hofland L.J. Differential expression of somatostatin receptor subtypes in human peripheral blood mononuclear cell subsets. Eur. J. Endocrinol. 2004, 150:565-577.
29. Medzhitov R. Recognition of microorganisms and activation of the immune response. Nature 2007, 449:819-826.
30. Nagasawa T., Hirota S., Tachibana K., Takakura N., Nishikawa S., Kitamura Y., Yoshida N., Kikutani H., Kishimoto T. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996, 382:635-638.
31. Pareek R., Wellnitz O., Van Dorp R., Burton J., Kerr D.E. Immunorelevant gene expression in LPS-challenged bovine mammary epithelial cells. J. Appl. Genet. 2005, 46:171-177.
32. Picard C., Puel A., Bonnet M., Ku C.L., Bustamante J., Yang K., Soudais C., Dupuis S., Feinberg J., Fieschi C., Elbim C., Hitchcock R., Lammas D., Davies G., Al-Ghonaium A., Al-Rayes H., Al-Jumaah S., Al-Hajjar S., Al-Mohsen I.Z., Frayha H.H., Rucker R., Hawn T.R., Aderem A., Tufenkeji H., Haraguchi S., Day N.K., Good R.A., Gougerot-Pocidalo M.A., Ozinsky A., Casanova J.L. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003, 299:2076-2079.
33. Ragnarsdóttir B., Jönsson K., Urbano A., Grönberg-Hernandez J., Lutay N., Tammi M., Gustafsson M., Lundstedt A.-C., Leijonhufvud I., Karpman D., Wullt B., Truedsson L., Jodal U., Andersson B., Svanborg C. Toll-like receptor 4 promoter polymorphisms: Common TLR4 variants may protect against severe urinary tract infection. PLoS One 2010, 5:e10734.
34. Rupp R., Boichard D. Genetics of resistance to mastitis in dairy cattle. Vet. Res. 2003, 34:671-688.
35. Sharma B.S., Leyva I., Schenkel F., Karrow N.A. Association of toll-like receptor 4 polymorphisms with somatic cell score and lactation persistency in Holstein bulls. J. Dairy Sci. 2006, 89:3626-3635.
36. Smyth G. Limma: Linear models for microarray data. Bioinformatics and Computational Biology Solutions using R and Bioconductor 2005, Springer Verlag, Berlin, Germany, Pages 397-420.
37. Sugimoto M., Fujikawa A., Womack J.E., Sugimoto Y. Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance. Proc. Natl. Acad. Sci. USA 2006, 103:6454-6459.
38. R Development Core Team. 2009. R: A Language and Environment for Statistical Computing. http://www.r-project.org/.
39. Van Werven T., Noordhuizen-Stassen E.N., Daemen A.J., Schukken Y.H., Brand A., Burvenich C. Preinfection in vitro chemotaxis, phagocytosis, oxidative burst, and expression of CD11/CD18 receptors and their predictive capacity on the outcome of mastitis induced in dairy cows with Escherichia coli. J. Dairy Sci. 1997, 80:67-74.
40. von Bernuth H., Picard C., Jin Z., Pankla R., Xiao H., Ku C.L., Chrabieh M., Mustapha I.B., Ghandil P., Camcioglu Y., Vasconcelos J., Sirvent N., Guedes M., Vitor A.B., Herrero-Mata M.J., Arostegui J.I., Rodrigo C., Alsina L., Ruiz-Ortiz E., Juan M., Fortuny C., Yague J., Anton J., Pascal M., Chang H.H., Janniere L., Rose Y., Garty B.Z., Chapel H., Issekutz A., Marodi L., Rodriguez-Gallego C., Banchereau J., Abel L., Li X., Chaussabel D., Puel A., Casanova J.L. Pyogenic bacterial infections in humans with MyD88 deficiency. Science 2008, 321:691-696.
41. Wenz J.R., Barrington G.M., Garry F.B., Ellis R.P., Magnuson R.J. Escherichia coli isolates' serotypes, genotypes, and virulence genes and clinical coliform mastitis severity. J. Dairy Sci. 2006, 89:3408-3412.
42. Wilson C.L., Miller C.J. Simpleaffy: A BioConductor package for Affymetrix quality control and data analysis. Bioinformatics 2005, 21:3683.
43. Yang W., Zerbe H., Petzl W., Brunner R.M., Gunther J., Draing C., von Aulock S., Schuberth H.J., Seyfert H.M. Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. Mol. Immunol. 2008, 45:1385-1397.
44. Zhang G., Ghosh S. Toll-like receptor-mediated NF- B activation: A phylogenetically conserved paradigm in innate immunity. J. Clin. Invest. 2001, 107:13-19.