-
1
-
-
0030480250
-
Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism
-
Hakomori, S. (1996) Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res. 56, 5309-5318.
-
(1996)
Cancer Res.
, vol.56
, pp. 5309-5318
-
-
Hakomori, S.1
-
2
-
-
78049507803
-
Gangliosides as regulators of cell membrane organization and functions
-
Sonnino, S. and Prinetti, A. (2010) Gangliosides as regulators of cell membrane organization and functions. Adv. Exp. Med. Biol. 688, 165-184.
-
(2010)
Adv. Exp. Med. Biol.
, vol.688
, pp. 165-184
-
-
Sonnino, S.1
Prinetti, A.2
-
3
-
-
9244234958
-
Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside)
-
DOI 10.1073/pnas.0407297101
-
Miura, Y., Kainuma, M., Jiang, H., Velasco, H., Vogt, P.K. and Hakomori, S. (2004) Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside). Proc. Natl. Acad. Sci. U. S. A. 101, 16204-16209. (Pubitemid 39552823)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.46
, pp. 16204-16209
-
-
Miura, Y.1
Kainuma, M.2
Jiang, H.3
Velasco, H.4
Vogt, P.K.5
Hakomori, S.6
-
4
-
-
0036677372
-
Glycosylation defining cancer malignancy: New wine in an old bottle
-
Hakomori, S. (2002) Glycosylation defining cancer malignancy: new wine in an old bottle. Proc. Natl. Acad. Sci. U. S. A. 99, 10231-10233.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10231-10233
-
-
Hakomori, S.1
-
5
-
-
80054024963
-
Role of gangliosides and plasma membrane-associated sialidase in the process of cell membrane organization
-
Sonnino, S., Chigorno, V., Aureli, M., Masilamani, A.P., Valsecchi, M., Loberto, N., Prioni, S., Mauri, L. and Prinetti, A. (2011) Role of gangliosides and plasma membrane-associated sialidase in the process of cell membrane organization. Adv. Exp. Med. Biol. 705, 297-316.
-
(2011)
Adv. Exp. Med. Biol.
, vol.705
, pp. 297-316
-
-
Sonnino, S.1
Chigorno, V.2
Aureli, M.3
Masilamani, A.P.4
Valsecchi, M.5
Loberto, N.6
Prioni, S.7
Mauri, L.8
Prinetti, A.9
-
6
-
-
80055097459
-
Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process
-
Freire-de-Lima, L., Gelfenbeyn, K., Ding, Y., Mandel, U., Clausen, H., Handa, K. and Hakomori, S. (2011) Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process. Proc. Natl. Acad. Sci. U. S. A. 108, 17690-17695.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 17690-17695
-
-
Freire-de-Lima, L.1
Gelfenbeyn, K.2
Ding, Y.3
Mandel, U.4
Clausen, H.5
Handa, K.6
Hakomori, S.7
-
7
-
-
78649725167
-
Functional role of gangliotetraosylceramide in epithelial-to-mesenchymal transition process induced by hypoxia and by TGF-b
-
Guan, F., Schaffer, L., Handa, K. and Hakomori, S. (2010) Functional role of gangliotetraosylceramide in epithelial-to-mesenchymal transition process induced by hypoxia and by TGF-b. FASEB J. 24, 4889-4903.
-
(2010)
FASEB J.
, vol.24
, pp. 4889-4903
-
-
Guan, F.1
Schaffer, L.2
Handa, K.3
Hakomori, S.4
-
8
-
-
66149101390
-
Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines
-
Guan, F., Handa, K. and Hakomori, S. (2009) Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines. Proc. Natl. Acad. Sci. U. S. A. 106, 7461-7466.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 7461-7466
-
-
Guan, F.1
Handa, K.2
Hakomori, S.3
-
9
-
-
0020358296
-
Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells
-
DOI 10.1083/jcb.95.1.333
-
Greenburg, G. and Hay, E.D. (1982) Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells. J. Cell Biol. 95, 333-339. (Pubitemid 13197104)
-
(1982)
Journal of Cell Biology
, vol.95
, Issue.1
, pp. 333-339
-
-
Greenburg, G.1
Hay, E.D.2
-
10
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
Basel
-
Hay, E.D. (1995) An overview of epithelio-mesenchymal transformation. Acta Anat. (Basel) 154, 8-20.
-
(1995)
Acta Anat.
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
11
-
-
80052712201
-
The ins and outs of the epithelial to mesenchymal transition in health and disease
-
Nieto, M.A. (2011) The ins and outs of the epithelial to mesenchymal transition in health and disease. Annu. Rev. Cell Dev. Biol. 27, 347-376.
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 347-376
-
-
Nieto, M.A.1
-
12
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. and Weinberg, R.A. (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
70450198396
-
Epithelialmesenchymal transitions in development and disease
-
Thiery, J.P., Acloque, H., Huang, R.Y. and Nieto, M.A. (2009) Epithelialmesenchymal transitions in development and disease. Cell 139, 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
14
-
-
33645302628
-
The epithelialmesenchymal transition: New insights in signaling, development, and disease
-
Lee, J.M., Dedhar, S., Kalluri, R. and Thompson, E.W. (2006) The epithelialmesenchymal transition: new insights in signaling, development, and disease. J. Cell Biol. 172, 973-981.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
15
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
DOI 10.1172/JCI200320530
-
Kalluri, R. and Neilson, E.G. (2003) Epithelial-mesenchymal transition and its implications for fibrosis. J. Clin. Invest. 112, 1776-1784. (Pubitemid 38063698)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
16
-
-
0342371891
-
The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: Its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma
-
DOI 10.1073/pnas.82.19.6517
-
Matsuura, H. and Hakomori, S. (1985) The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma. Proc. Natl. Acad. Sci. U. S. A. 82, 6517-6521. (Pubitemid 16230545)
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, Issue.19
, pp. 6517-6521
-
-
Matsuura, H.1
Hakomori, S.I.2
-
17
-
-
0023831538
-
The oncofetal structure of human fibronectin defined by monoclonal antibody FDC-6. Unique structural requirement for the antigenic specificity provided by a glycosylhexapeptide
-
Matsuura, H., Takio, K., Titani, K., Greene, T., Levery, S.B., Salyan, M.E.K. and Hakomori, S. (1988) The oncofetal structure of human fibronectin defined by monoclonal antibody FDC-6: Unique structural requirement for the antigenic specificity provided by a glycosylhexapeptide. J. Biol. Chem. 263, 3314-3322. (Pubitemid 18072789)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.7
, pp. 3314-3322
-
-
Matsuura, H.1
Takio, K.2
Titani, K.3
Greene, T.4
Levery, S.B.5
Salyan, M.E.K.6
Hakomori, S.7
-
18
-
-
0024316015
-
An a-N-acetylgalactosaminylation at the threonine residue of a defined peptide sequence creates the oncofetal peptide epitope in human fibronectin
-
Matsuura, H., Greene, T. and Hakomori, S. (1989) An a- Nacetylgalactosaminylation at the threonine residue of a defined peptide sequence creates the oncofetal peptide epitope in human fibronectin. J. Biol. Chem. 264, 10472-10476. (Pubitemid 19161611)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.18
, pp. 10472-10476
-
-
Matsuura, H.1
Greene, T.2
Hakomori, S.3
-
19
-
-
0033520457
-
Cloning and characterization of a close homologue of human UDP-Nacetyl-alpha-D-galactosamine:Polypeptide Nacetylgalactosaminyltransferase- T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy
-
Bennett, E.P., Hassan, H., Mandel, U., Hollingsworth, M.A., Akisawa, N., Ikematsu, Y., Merkx, G., Geurts van Kessel, A., Olofsson, S. and Clausen, H. (1999) Cloning and characterization of a close homologue of human UDP-Nacetyl-alpha-D-galactosamine:Polypeptide Nacetylgalactosaminyltransferase- T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy. J. Biol. Chem. 274, 25362-25370.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25362-25370
-
-
Bennett, E.P.1
Hassan, H.2
Mandel, U.3
Hollingsworth, M.A.4
Akisawa, N.5
Ikematsu, Y.6
Merkx, G.7
Geurts Van Kessel, A.8
Olofsson, S.9
Clausen, H.10
-
20
-
-
41149147556
-
Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway
-
DOI 10.1073/pnas.0709619104
-
Todeschini, A.R., Dos Santos, J.N., Handa, K. and Hakomori, S. (2008) Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway. Proc. Natl. Acad. Sci. U. S. A. 105, 1925-1930. (Pubitemid 351439441)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 1925-1930
-
-
Todeschini, A.R.1
Dos, S.J.N.2
Handa, K.3
Hakomori, S.-I.4
-
21
-
-
0017375736
-
Binding of soluble form of fibroblast surface protein, fibronectin, to collagen
-
Engvall, E. and Ruoslahti, E. (1977) Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. Int. J. Cancer 20, 1-5. (Pubitemid 8139735)
-
(1977)
International Journal of Cancer
, vol.20
, Issue.1
, pp. 1-5
-
-
Engvall, E.1
Ruoslahti, E.2
-
22
-
-
34247184670
-
Ganglioside GM2-tetraspanin CD82 complex inhibits Met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse
-
DOI 10.1074/jbc.M611407200
-
Todeschini, A.R., Dos Santos, J.N., Handa, K. and Hakomori, S. (2007) Ganglioside GM2-tetraspanin CD82 complex inhibits Met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse. J. Biol. Chem. 282, 8123-8133. (Pubitemid 47093583)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.11
, pp. 8123-8133
-
-
Todeschini, A.R.1
Dos, S.J.N.2
Handa, K.3
Hakomori, S.-I.4
-
23
-
-
27444438906
-
A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of alpha3beta1 integrin with CD9
-
DOI 10.1074/jbc.M505630200
-
Mitsuzuka, K., Handa, K., Satoh, M., Arai, Y. and Hakomori, S. (2005) A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of alpha3beta1 integrin with CD9. J. Biol. Chem. 280, 35545-35553. (Pubitemid 41532746)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35545-35553
-
-
Mitsuzuka, K.1
Handa, K.2
Satoh, M.3
Arai, Y.4
Hakomori, S.5
-
24
-
-
4544250815
-
Cell growth regulation through GM3-enriched microdomain (glycosynapse) in human lung embryonal fibroblast WI38 and its oncogenic transformant VA13
-
DOI 10.1074/jbc.M403857200
-
Toledo, M.S., Suzuki, E., Handa, K. and Hakomori, S. (2004) Cell growth regulation through GM3-enriched microdomain (glycosynapse) in human lung embryonal fibroblast WI38 and its oncogenic transformant VA13. J. Biol. Chem. 279, 34655-34664. (Pubitemid 39318095)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34655-34664
-
-
Toledo, M.S.1
Suzuki, E.2
Handa, K.3
Hakomori, S.4
-
25
-
-
79952106660
-
Location, location, location: New insights into O-GalNAc protein glycosylation
-
Gill, D.J., Clausen, H. and Bard, F. (2011) Location, location, location: new insights into O-GalNAc protein glycosylation. Trends Cell Biol. 21, 149-158.
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 149-158
-
-
Gill, D.J.1
Clausen, H.2
Bard, F.3
-
26
-
-
84857445346
-
Control of Mucin-Type O-Glycosylation - A Classification of the Polypeptide GalNAc-transferase Gene Family
-
Epub ahead of print
-
Bennett, E.P., Mandel, U., Clausen, H., Gerken, T.A., Fritz, T.A. and Tabak, L.A. (2011) Control of Mucin-Type O-Glycosylation - A Classification of the Polypeptide GalNAc-transferase Gene Family. Glycobiology [Epub ahead of print].
-
(2011)
Glycobiology
-
-
Bennett, E.P.1
Mandel, U.2
Clausen, H.3
Gerken, T.A.4
Fritz, T.A.5
Tabak, L.A.6
-
27
-
-
0004106191
-
-
2nd edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY)
-
Varki, A., Etzler, M.E., Cummings, R.D. and Esko, J.D. (2008) Essentials of Glycobiology, 2nd edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY). 115-127.
-
(2008)
Essentials of Glycobiology
, pp. 115-127
-
-
Varki, A.1
Etzler, M.E.2
Cummings, R.D.3
Esko, J.D.4
-
28
-
-
80255141853
-
Mining the O-glycoproteome using zinc-finger nucleaseglycoengineered SimpleCell lines
-
Steentoft, C., Vakhrushev, S.Y., Vester-Christensen, M.B., Schjoldager, K.T., Kong, Y., Bennett, E.P., Mandel, U., Wandall, H., Levery, S.B. and Clausen, H. (2011) Mining the O-glycoproteome using zinc-finger nucleaseglycoengineered SimpleCell lines. Nat. Methods 8, 977-982.
-
(2011)
Nat. Methods
, vol.8
, pp. 977-982
-
-
Steentoft, C.1
Vakhrushev, S.Y.2
Vester-Christensen, M.B.3
Schjoldager, K.T.4
Kong, Y.5
Bennett, E.P.6
Mandel, U.7
Wandall, H.8
Levery, S.B.9
Clausen, H.10
-
29
-
-
79959596406
-
Fibronectin splice variants: Understanding their multiple roles in health and disease using engineered mouse models
-
White, E.S. and Muro, A.F. (2011) Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models. IUBMB. Life 63, 538-546.
-
(2011)
IUBMB. Life
, vol.63
, pp. 538-546
-
-
White, E.S.1
Muro, A.F.2
-
30
-
-
50249176028
-
New insights into form and function of fibronectin splice variants
-
White, E.S., Baralle, F.E. and Muro, A.F. (2008) New insights into form and function of fibronectin splice variants. J. Pathol. 216, 1-14.
-
(2008)
J. Pathol.
, vol.216
, pp. 1-14
-
-
White, E.S.1
Baralle, F.E.2
Muro, A.F.3
-
31
-
-
0037107551
-
Fibronectin at a glance
-
DOI 10.1242/jcs.00059
-
Pankov, R. and Yamada, K.M. (2002) Fibronectin at a glance. J. Cell Sci. 115, 3861-3863. (Pubitemid 35256486)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.20
, pp. 3861-3863
-
-
Pankov, R.1
Yamada, K.M.2
-
32
-
-
0023392493
-
Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon
-
Zardi, L., Carnemolla, B., Siri, A., Petersen, T.E., Paolella, G., Sebastio, G. and Baralle, F.E. (1987) Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO J. 6, 2337-2342.
-
(1987)
EMBO J.
, vol.6
, pp. 2337-2342
-
-
Zardi, L.1
Carnemolla, B.2
Siri, A.3
Petersen, T.E.4
Paolella, G.5
Sebastio, G.6
Baralle, F.E.7
-
33
-
-
79953708277
-
Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin
-
Park, J.H., Katagiri, T., Chung, S., Kijima, K. and Nakamura, Y. (2011) Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin. Neoplasia 13, 320-326.
-
(2011)
Neoplasia
, vol.13
, pp. 320-326
-
-
Park, J.H.1
Katagiri, T.2
Chung, S.3
Kijima, K.4
Nakamura, Y.5
-
34
-
-
79954570719
-
Myofibroblast differentiation during fibrosis: Role of NAD(P)H oxidases
-
Barnes, J.L. and Gorin, Y. (2011) Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int. 79, 944-956.
-
(2011)
Kidney Int.
, vol.79
, pp. 944-956
-
-
Barnes, J.L.1
Gorin, Y.2
|