Cigarette smoking, coffee drinking, and ingestion of charcoal-broiled beef as potential modifiers of drug therapy and confounders of clinical trials

Journal of Pharmacology and Experimental Therapeutics

Volumn 342, Issue 1, 2012, Pages 9-14

  Conney, Allan H ^a,b   Reidenberg, M M ^c  

^a RUTGERS UNIVERSITY   (United States)

^b GUANGDONG UNIVERSITY OF TECHNOLOGY   (China)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CAFFEINE; CHARCOAL; CLOZAPINE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; DESIPRAMINE; FLUOROURACIL; FLUVOXAMINE; HALOPERIDOL; NARCOTIC ANALGESIC AGENT; NORTRIPTYLINE; PHENACETIN; POLYCYCLIC AROMATIC HYDROCARBON; TACRINE; TOBACCO SMOKE; ZOXAZOLAMINE;

BEEF; CHRONIC PAIN; CIGARETTE SMOKING; CLINICAL TRIAL (TOPIC); COFFEE; COLORECTAL CANCER; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG MONITORING; DRUG SALIVA LEVEL; ENVIRONMENTAL FACTOR; FOOD PROCESSING; GENETIC POLYMORPHISM; HUMAN; LIVER METABOLISM; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; REVIEW; UNSPECIFIED SIDE EFFECT; XENOBIOTIC METABOLISM;

ANIMALS; BENZO(A)PYRENE; CHARCOAL; CLINICAL TRIALS AS TOPIC; COFFEE; FOOD-DRUG INTERACTIONS; HUMANS; MALE; MEAT; METABOLIC DETOXICATION, DRUG; METHYLCHOLANTHRENE; MICE; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; SMOKING;

EID: 84862499677     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.193193     Document Type: Review

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