Serum microRNA signatures identified by Solexa sequencing predict sepsis patients' mortality: A prospective observational study

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Wang, Huijuan ^a,b,c   Zhang, Pengjun ^b,c   Chen, Weijun ^d   Feng, Dan ^c   Jia, Yanhong ^c   Xie, Lixin ^a,c  

^a Hainan Branch of Chinese PLA General Hospital   (China)

^b NANKAI UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d Chinese Academy of Sciences and China National Center for Bioinformation   (China)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; MICRORNA; MICRORNA 122; MICRORNA 15A; MICRORNA 15B; MICRORNA 16; MICRORNA 193B; MICRORNA 206; MICRORNA 223; MICRORNA 378; MICRORNA 451; MICRORNA 483 5P; MICRORNA 486 5P; MICRORNA 499 5P; PROCALCITONIN; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG;

ADULT; APACHE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; PREDICTIVE VALUE; PROGNOSIS; PROLACTIN BLOOD LEVEL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA SEQUENCE; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SEPSIS; SEPTIC SHOCK; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SURVIVOR;

ADULT; AGED; AREA UNDER CURVE; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; ROC CURVE; SEPSIS;

EID: 84862491062     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038885     Document Type: Article

References (37)

1. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, et al. (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368-1377.
2. Kampmeier TG, Rehberg S, Westphal M, Lange M, (2010) Vasopressin in sepsis and septic shock. Minerva Anestesiol 76: 844-850.
3. Hillas G, Vassilakopoulos T, Plantza P, Rasidakis A, Bakakos P, (2010) C-reactive protein and procalcitonin as predictors of survival and septic shock in ventilator-associated pneumonia. Eur Respir J 35: 805-811.
4. Chen SJ, Chao TF, Chiang MC, Kuo SC, Chen LY, et al. (2011) Prediction of patient outcome from Acinetobacter baumannii bacteremia with Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) II scores. Intern Med 50: 871-877.
5. Silvestre J, Povoa P, Coelho L, Almeida E, Moreira P, et al. (2009) Is C-reactive protein a good prognostic marker in septic patients? Intensive Care Med 35: 909-913.
6. Fritz HG, Brandes H, Bredle DL, Bitterlich A, Vollandt R, et al. (2003) Post-operative hypoalbuminaemia and procalcitonin elevation for prediction of outcome in cardiopulmonary bypass surgery. Acta Anaesthesiol Scand 47: 1276-1283.
7. Bellon M, Lepelletier Y, Hermine O, Nicot C, (2009) Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia. Blood 113: 4914-4917.
8. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
9. Chen X, Ba Y, Ma L, Cai X, Yin Y, et al. (2008) Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18: 997-1006.
10. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105: 10513-10518.
11. Hu Z, Chen X, Zhao Y, Tian T, Jin G, et al. (2010) Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol 28: 1721-1726.
12. Vasilescu C, Rossi S, Shimizu M, Tudor S, Veronese A, et al. (2009) MicroRNA fingerprints identify miR-150 as a plasma prognostic marker in patients with sepsis. PLoS One 4: e7405.
13. Li J, Wan Y, Guo Q, Zou L, Zhang J, et al. (2010) Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis. Arthritis Res Ther 12: R81.
14. Schmid R, Baum P, Ittrich C, Fundel-Clemens K, Huber W, et al. (2010) Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3. BMC Genomics 11: 349.
15. Keller A, Leidinger P, Borries A, Wendschlag A, Wucherpfennig F, et al. (2009) miRNAs in lung cancer- studying complex fingerprints in patient's blood cells by microarray experiments. BMC Cancer 9: 353.
16. Liu R, Zhang C, Hu Z, Li G, Wang C, et al. (2011) A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur J Cancer 47: 784-791.
17. Wu Q, Lu Z, Li H, Lu J, Guo L, et al. (2011) Next-Generation Sequencing of MicroRNAs for Breast Cancer Detection. J Biomed Biotechnol 2011: 597145.
18. Git A, Dvinge H, Salmon-Divon M, Osborne M, Kutter C, et al. (2010) Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression. RNA 16: 991-1006.
19. Zhu E, Zhao F, Xu G, Hou H, Zhou L, et al. (2010) mirTools: microRNA profiling and discovery based on high-throughput sequencing. Nucleic Acids Res 38: W392-397.
20. Wang F, Wang J, Liu D, Su Y, (2010) Normalizing genes for real-time polymerase chain reaction in epithelial and nonepithelial cells of mouse small intestine. Anal Biochem 399: 211-217.
21. Gui J, Tian Y, Wen X, Zhang W, Zhang P, et al. (2011) Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies. Clin Sci (Lond) 120: 183-193.
22. Wang ZX, Bian HB, Wang JR, Cheng ZX, Wang KM, et al. (2011) Prognostic significance of serum miRNA-21 expression in human non-small cell lung cancer. J Surg Oncol.
23. Wu H, Neilson JR, Kumar P, Manocha M, Shankar P, et al. (2007) miRNA profiling of naive, effector and memory CD8 T cells. PLoS One 2: e1020.
24. Schmidt WM, Spiel AO, Jilma B, Wolzt M, Muller M, (2009) In vivo profile of the human leukocyte microRNA response to endotoxemia. Biochem Biophys Res Commun 380: 437-441.
25. Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, et al. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9: 654-659.
26. Janowska-Wieczorek A, Wysoczynski M, Kijowski J, Marquez-Curtis L, Machalinski B, et al. (2005) Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer. Int J Cancer 113: 752-760.
27. Hunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, et al. (2008) Detection of microRNA expression in human peripheral blood microvesicles. PLoS One 3: e3694.
28. Li T, Morgan MJ, Choksi S, Zhang Y, Kim YS, et al. (2010) MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. Nat Immunol 11: 799-805.
29. Chen J, Zhang X, Lentz C, Abi-Daoud M, Pare GC, et al. (2011) miR-193b Regulates Mcl-1 in Melanoma. Am J Pathol.
30. Chen J, Feilotter HE, Pare GC, Zhang X, Pemberton JG, et al. (2010) MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma. Am J Pathol 176: 2520-2529.
31. Mizuguchi Y, Mishima T, Yokomuro S, Arima Y, Kawahigashi Y, et al. (2011) Sequencing and bioinformatics-based analyses of the microRNA transcriptome in hepatitis B-related hepatocellular carcinoma. PLoS One 6: e15304.
32. Bihrer V, Friedrich-Rust M, Kronenberger B, Forestier N, Haupenthal J, et al. (2011) Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection. Am J Gastroenterol 106: 1663-1669.
33. Soon PS, Tacon LJ, Gill AJ, Bambach CP, Sywak MS, et al. (2009) miR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical Cancer. Clin Cancer Res 15: 7684-7692.
34. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, et al. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101: 1644-1655.
35. Hafner M, Landgraf P, Ludwig J, Rice A, Ojo T, et al. (2008) Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods 44: 3-12.
36. Calabrese JM, Seila AC, Yeo GW, Sharp PA, (2007) RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc Natl Acad Sci U S A 104: 18097-18102.
37. Ruby JG, Jan C, Player C, Axtell MJ, Lee W, et al. (2006) Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 127: 1193-1207.