메뉴 건너뛰기




Volumn 59, Issue 2, 2012, Pages 403-409

21 Days head-down bed rest induces weakening of cell-mediated immunity - Some spaceflight findings confirmed in a ground-based analog

Author keywords

Bed rest; CMV QuantiFERON; Microgravity; T cells

Indexed keywords

ANTIBIOTIC AGENT; CANDIDA ANTIGEN; CD4 ANTIGEN; CLINDAMYCIN; FUNGICIDE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; PHYTOHEMAGGLUTININ; POTASSIUM BICARBONATE; T LYMPHOCYTE ANTIGEN; TETANUS TOXOID; TRANSCRIPTION FACTOR FOXP3; TUBERCULIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84862322182     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.04.032     Document Type: Article
Times cited : (27)

References (29)
  • 1
    • 0028330129 scopus 로고
    • Cellular immunity in cosmonauts during long duration spaceflight on board the orbital MIR station
    • Gmunder F.K., Konstantinova I., Cogoli A., Lesnyak A., Bogomolov W., et al. Cellular immunity in cosmonauts during long duration spaceflight on board the orbital MIR station. Aviat Space Environ Med 1994, 65:419-423.
    • (1994) Aviat Space Environ Med , vol.65 , pp. 419-423
    • Gmunder, F.K.1    Konstantinova, I.2    Cogoli, A.3    Lesnyak, A.4    Bogomolov, W.5
  • 2
    • 0026696043 scopus 로고
    • In vivo testing confirms a blunting of the human cell-mediated immune mechanism during space flight
    • Taylor G.R., Janney R.P. In vivo testing confirms a blunting of the human cell-mediated immune mechanism during space flight. J Leukoc Biol 1992, 51:129-132.
    • (1992) J Leukoc Biol , vol.51 , pp. 129-132
    • Taylor, G.R.1    Janney, R.P.2
  • 3
    • 0027897818 scopus 로고
    • The effect of space flight on human cellular immunity
    • Cogoli A. The effect of space flight on human cellular immunity. Environ Med 1993, 37:107-116.
    • (1993) Environ Med , vol.37 , pp. 107-116
    • Cogoli, A.1
  • 4
    • 66749185337 scopus 로고    scopus 로고
    • Effects of spaceflight on innate immune function and antioxidant gene expression
    • Baqai F.P., Gridley D.S., Slater J.M., Luo-Owen X., Stodieck L.S., et al. Effects of spaceflight on innate immune function and antioxidant gene expression. J Appl Physiol 2009, 106:1935-1942.
    • (2009) J Appl Physiol , vol.106 , pp. 1935-1942
    • Baqai, F.P.1    Gridley, D.S.2    Slater, J.M.3    Luo-Owen, X.4    Stodieck, L.S.5
  • 5
    • 58649114518 scopus 로고    scopus 로고
    • Spaceflight effects on T lymphocyte distribution, function and gene expression
    • Gridley D.S., Slater J.M., Luo-Owen X., Rizvi A., Chapes S.K., et al. Spaceflight effects on T lymphocyte distribution, function and gene expression. J Appl Physiol 2009, 106:194-202.
    • (2009) J Appl Physiol , vol.106 , pp. 194-202
    • Gridley, D.S.1    Slater, J.M.2    Luo-Owen, X.3    Rizvi, A.4    Chapes, S.K.5
  • 6
    • 0035432020 scopus 로고    scopus 로고
    • CDNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat)
    • Lewis M.L., Cubano L.A., Zhao B., Dinh H.K., Pabalan J.G., et al. cDNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat). FASEB J 2001, 15:1783-1785.
    • (2001) FASEB J , vol.15 , pp. 1783-1785
    • Lewis, M.L.1    Cubano, L.A.2    Zhao, B.3    Dinh, H.K.4    Pabalan, J.G.5
  • 7
    • 36049010104 scopus 로고    scopus 로고
    • Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq
    • Wilson J.W., Ott C.M., Honer zu B.K., Ramamurthy R., Quick L., et al. Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. Proc Natl Acad Sci USA 2007, 104:16299-16304.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16299-16304
    • Wilson, J.W.1    Ott, C.M.2    Honer zu, B.K.3    Ramamurthy, R.4    Quick, L.5
  • 8
    • 70350741504 scopus 로고    scopus 로고
    • Could spaceflight-associated immune system weakening preclude the expansion of human presence beyond Earth's orbit?
    • Gueguinou N., Huin-Schohn C., Bascove M., Bueb J.L., Tschirhart E., et al. Could spaceflight-associated immune system weakening preclude the expansion of human presence beyond Earth's orbit?. J Leukoc Biol 2009, 86:1027-1038.
    • (2009) J Leukoc Biol , vol.86 , pp. 1027-1038
    • Gueguinou, N.1    Huin-Schohn, C.2    Bascove, M.3    Bueb, J.L.4    Tschirhart, E.5
  • 9
    • 51149084801 scopus 로고    scopus 로고
    • Immune system dysregulation following short- vs long-duration spaceflight
    • Crucian B.E., Stowe R.P., Pierson D.L., Sams C.F. Immune system dysregulation following short- vs long-duration spaceflight. Aviat Space Environ Med 2008, 79:835-843.
    • (2008) Aviat Space Environ Med , vol.79 , pp. 835-843
    • Crucian, B.E.1    Stowe, R.P.2    Pierson, D.L.3    Sams, C.F.4
  • 10
    • 0033937197 scopus 로고    scopus 로고
    • Altered cytokine production by specific human peripheral blood cell subsets immediately following space flight
    • Crucian B.E., Cubbage M.L., Sams C.F. Altered cytokine production by specific human peripheral blood cell subsets immediately following space flight. J Interferon Cytokine Res 2000, 20:547-556.
    • (2000) J Interferon Cytokine Res , vol.20 , pp. 547-556
    • Crucian, B.E.1    Cubbage, M.L.2    Sams, C.F.3
  • 12
    • 0033710839 scopus 로고    scopus 로고
    • Reactivation and shedding of cytomegalovirus in astronauts during spaceflight
    • Mehta S.K., Stowe R.P., Feiveson A.H., Tyring S.K., Pierson D.L. Reactivation and shedding of cytomegalovirus in astronauts during spaceflight. J Infect Dis 2000, 182:1761-1764.
    • (2000) J Infect Dis , vol.182 , pp. 1761-1764
    • Mehta, S.K.1    Stowe, R.P.2    Feiveson, A.H.3    Tyring, S.K.4    Pierson, D.L.5
  • 15
    • 81455158795 scopus 로고    scopus 로고
    • Artificial gravity with ergometric exercise preserves the cardiac but not cerebrovascular functions during 4days of head-down bed rest
    • Yang C.B., Wang Y.C., Gao Y., Geng J., Wu Y.H., et al. Artificial gravity with ergometric exercise preserves the cardiac but not cerebrovascular functions during 4days of head-down bed rest. Cytokine 2011, 56:648-655.
    • (2011) Cytokine , vol.56 , pp. 648-655
    • Yang, C.B.1    Wang, Y.C.2    Gao, Y.3    Geng, J.4    Wu, Y.H.5
  • 16
    • 66949144096 scopus 로고    scopus 로고
    • Immune status, latent, viral reactivation, and stress during long-duration head-down bed rest
    • Crucian B.E., Stowe R.P., Mehta S.K., Yetman D.L., Leal M.J., et al. Immune status, latent, viral reactivation, and stress during long-duration head-down bed rest. Aviat Space Environ Med 2009, 80:A37-A44.
    • (2009) Aviat Space Environ Med , vol.80
    • Crucian, B.E.1    Stowe, R.P.2    Mehta, S.K.3    Yetman, D.L.4    Leal, M.J.5
  • 17
    • 63449109853 scopus 로고    scopus 로고
    • Immune responses in adult female volunteers during the bed-rest model of spaceflight: antibodies and cytokines
    • Shearer W.T., Ochs H.D., Lee B.N., Cohen E.N., Reuben J.M., et al. Immune responses in adult female volunteers during the bed-rest model of spaceflight: antibodies and cytokines. J Allergy Clin Immunol 2009, 123:900-905.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 900-905
    • Shearer, W.T.1    Ochs, H.D.2    Lee, B.N.3    Cohen, E.N.4    Reuben, J.M.5
  • 19
    • 65249148542 scopus 로고    scopus 로고
    • Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients
    • Kumar D., Chernenko S., Moussa G., Cobos I., Manuel O., et al. Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients. Am J Transplant 2009, 9:1214-1222.
    • (2009) Am J Transplant , vol.9 , pp. 1214-1222
    • Kumar, D.1    Chernenko, S.2    Moussa, G.3    Cobos, I.4    Manuel, O.5
  • 21
    • 77952500102 scopus 로고    scopus 로고
    • Discrete changes in circulating regulatory T cells during infliximab treatment of Crohn's disease
    • Hvas C.L., Kelsen J., Agnholt J., Dige A., Christensen L.A., et al. Discrete changes in circulating regulatory T cells during infliximab treatment of Crohn's disease. Autoimmunity 2010, 43:325-333.
    • (2010) Autoimmunity , vol.43 , pp. 325-333
    • Hvas, C.L.1    Kelsen, J.2    Agnholt, J.3    Dige, A.4    Christensen, L.A.5
  • 23
    • 79953329803 scopus 로고    scopus 로고
    • Infliximab induces clonal expansion of gammadelta-T cells in Crohn's disease: a predictor of lymphoma risk?
    • Kelsen J., Dige A., Schwindt H., D'Amore F., Pedersen F.S., et al. Infliximab induces clonal expansion of gammadelta-T cells in Crohn's disease: a predictor of lymphoma risk?. PLoS One 2011, 6:e17890.
    • (2011) PLoS One , vol.6
    • Kelsen, J.1    Dige, A.2    Schwindt, H.3    D'Amore, F.4    Pedersen, F.S.5
  • 25
    • 0026858708 scopus 로고
    • Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I Comparison with isolated PBMC stimulation
    • De G.D., Zangerle P.F., Gevaert Y., Fassotte M.F., Beguin Y., et al. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I Comparison with isolated PBMC stimulation. Cytokine 1992, 4:239-248.
    • (1992) Cytokine , vol.4 , pp. 239-248
    • De, G.D.1    Zangerle, P.F.2    Gevaert, Y.3    Fassotte, M.F.4    Beguin, Y.5
  • 26
    • 0028799209 scopus 로고
    • Cytokine-based human whole blood assay for the detection of antigen-reactive T cells
    • Petrovsky N., Harrison L.C. Cytokine-based human whole blood assay for the detection of antigen-reactive T cells. J Immunol Methods 1995, 186:37-46.
    • (1995) J Immunol Methods , vol.186 , pp. 37-46
    • Petrovsky, N.1    Harrison, L.C.2
  • 28
    • 67650500734 scopus 로고    scopus 로고
    • Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation
    • Elkord E. Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation. J Immunol Methods 2009, 347:87-90.
    • (2009) J Immunol Methods , vol.347 , pp. 87-90
    • Elkord, E.1
  • 29
    • 68149137514 scopus 로고    scopus 로고
    • Optimization and limitations of use of cryopreserved peripheral blood mononuclear cells for functional and phenotypic T-cell characterization
    • Weinberg A., Song L.Y., Wilkening C., Sevin A., Blais B., et al. Optimization and limitations of use of cryopreserved peripheral blood mononuclear cells for functional and phenotypic T-cell characterization. Clin Vaccine Immunol 2009, 16:1176-1186.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 1176-1186
    • Weinberg, A.1    Song, L.Y.2    Wilkening, C.3    Sevin, A.4    Blais, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.