메뉴 건너뛰기




Volumn 422, Issue 4, 2012, Pages 573-577

Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice

Author keywords

Connectivity mapping; Gaucher disease; GBA1; GD1; Microarray profiling; Pathway analysis

Indexed keywords

ALBENDAZOLE; CHITINASE; GLUCOSYLCERAMIDASE; OXAMNIQUINE;

EID: 84862301385     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.027     Document Type: Article
Times cited : (10)

References (20)
  • 1
    • 84862288061 scopus 로고    scopus 로고
    • Gaucher Disease, in: D. Valle (Ed.), The Online Metabolic and Molecular Bases of Inherited Disease, McGraw-Hill, (Chapter 146).
    • G.A. Grabowski, G.A. Petsko, E.H. Kolodny, Gaucher Disease, in: D. Valle (Ed.), The Online Metabolic and Molecular Bases of Inherited Disease, McGraw-Hill, 2010 (Chapter 146).
    • (2010)
    • Grabowski, G.A.1    Petsko, G.A.2    Kolodny, E.H.3
  • 3
    • 84862776523 scopus 로고    scopus 로고
    • Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation
    • Zhang C.K., Stein P.B., Liu J., Wang Z., Yang R., Cho J.H., Gregersen P.K., Aerts J.M., Zhao H., Pastores G.M., Mistry P.K. Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation. Am. J. Hematol. 2012, 87:377-383.
    • (2012) Am. J. Hematol. , vol.87 , pp. 377-383
    • Zhang, C.K.1    Stein, P.B.2    Liu, J.3    Wang, Z.4    Yang, R.5    Cho, J.H.6    Gregersen, P.K.7    Aerts, J.M.8    Zhao, H.9    Pastores, G.M.10    Mistry, P.K.11
  • 5
    • 80052672242 scopus 로고    scopus 로고
    • Gaucher disease and cancer: concept and controversy
    • F.Y. Choy, T.N. Campbell, Gaucher disease and cancer: concept and controversy, Int. J. Cell. Biol. 2011 (2011) 150450.
    • (2011) Int. J. Cell. Biol. , Issue.2011 , pp. 150450
    • Choy, F.Y.1    Campbell, T.N.2
  • 8
    • 15244348524 scopus 로고    scopus 로고
    • Gaucher disease and parkinsonism
    • Sidransky E. Gaucher disease and parkinsonism. Mol. Genet. Metab. 2005, 84:302-304.
    • (2005) Mol. Genet. Metab. , vol.84 , pp. 302-304
    • Sidransky, E.1
  • 9
    • 78650827299 scopus 로고    scopus 로고
    • Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults
    • Mistry P.K., Weinreb N.J., Kaplan P., Cole J.A., Gwosdow A.R., Hangartner T. Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults. Blood Cells Mol. Dis. 2011, 46:66-72.
    • (2011) Blood Cells Mol. Dis. , vol.46 , pp. 66-72
    • Mistry, P.K.1    Weinreb, N.J.2    Kaplan, P.3    Cole, J.A.4    Gwosdow, A.R.5    Hangartner, T.6
  • 14
    • 41049113128 scopus 로고    scopus 로고
    • Gaucher disease: unmet treatment needs
    • Mehta A. Gaucher disease: unmet treatment needs. Acta Paediatr. Suppl. 2008, 97:83-87.
    • (2008) Acta Paediatr. Suppl. , vol.97 , pp. 83-87
    • Mehta, A.1
  • 15
    • 0029135190 scopus 로고
    • Pathological findings in Gaucher disease type 2 patients following enzyme therapy
    • Bove K.E., Daugherty C., Grabowski G.A. Pathological findings in Gaucher disease type 2 patients following enzyme therapy. Hum. Pathol. 1995, 26:1040-1045.
    • (1995) Hum. Pathol. , vol.26 , pp. 1040-1045
    • Bove, K.E.1    Daugherty, C.2    Grabowski, G.A.3
  • 19
    • 84859633464 scopus 로고    scopus 로고
    • Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia
    • Stumpel D.J., Schneider P., Seslija L., Osaki H., Williams O., Pieters R., Stam R.W. Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia. Leukemia 2012, 26:682-692.
    • (2012) Leukemia , vol.26 , pp. 682-692
    • Stumpel, D.J.1    Schneider, P.2    Seslija, L.3    Osaki, H.4    Williams, O.5    Pieters, R.6    Stam, R.W.7
  • 20
    • 61849179838 scopus 로고    scopus 로고
    • Diltiazem, a L-type Ca(2+) channel blocker, also acts as a pharmacological chaperone in Gaucher patient cells
    • Rigat B., Mahuran D. Diltiazem, a L-type Ca(2+) channel blocker, also acts as a pharmacological chaperone in Gaucher patient cells. Mol. Genet. Metab. 2009, 96:225-232.
    • (2009) Mol. Genet. Metab. , vol.96 , pp. 225-232
    • Rigat, B.1    Mahuran, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.