Esophageal motor disorders: How to bridge the gap between advanced diagnostic tools and paucity of therapeutic modalities?

Journal of Clinical Gastroenterology

Volumn 46, Issue 6, 2012, Pages 442-448

  Clarke, John O ^a   Pandolfino, John E ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

achalasia; esophageal pressure topography; high resolution manometry; impedance planimetry

Indexed keywords

CHEMOSENSITIVITY; CLINICAL PRACTICE; ESOPHAGEAL PRESSURE TOPOGRAPHY; ESOPHAGUS ACHALASIA; ESOPHAGUS FUNCTION; ESOPHAGUS FUNCTION DISORDER; ESOPHAGUS MANOMETRY; ESOPHAGUS MOTILITY; ESOPHAGUS PRESSURE; ESOPHAGUS SPASM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; LATENT PERIOD; LOWER ESOPHAGUS SPHINCTER; MEASUREMENT; NOCICEPTION; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW;

ESOPHAGEAL ACHALASIA; ESOPHAGEAL MOTILITY DISORDERS; ESOPHAGEAL SPASM, DIFFUSE; ESOPHAGOGASTRIC JUNCTION; HUMANS; MANOMETRY; MUSCLE CONTRACTION; PRESSURE;

EID: 84862299017     PISSN: 01920790     EISSN: 15392031     Source Type: Journal    
DOI: 10.1097/MCG.0b013e31823d30c1     Document Type: Review

References (44)

1. Nayar DS, Khandwala F, Achkar E, et al. Esophageal manometry: Assessment of interpreter consistency. Clin Gastroenterol Hepatol. 2005;3:218-224.
2. Clouse RE, Staiano A. Topography of the esophageal peristaltic pressure wave. Am J Physiol. 1991;261:G677-G684.
3. Pandolfino JE, Ghosh SK, Zhang Q, et al. Quantifying EGJ morphology and relaxation with high-resolution manometry: A study of 75 asymptomatic volunteers. Am J Physiol Gastrointest Liver Physiol. 2006;290:G1033-G1040.
4. Ghosh SK, Pandolfino JE, Zhang Q, et al. Quantifying esophageal peristalsis with high-resolution manometry: A study of 75 asymptomatic volunteers. Am J Physiol Gastrointest Liver Physiol. 2006;290:G988-G997.
5. Ghosh SK, Pandolfino JE, Zhang Q, et al. Deglutitive upper esophageal sphincter relaxation: A study of 75 volunteer subjects using solid-state high-resolution manometry. Am J Physiol Gastrointest Liver Physiol. 2006;291:G525-G531.
6. Pohl D, Ribolsi M, Savarino E, et al. Characteristics of the esophageal low-pressure zone in healthy volunteers and patients with esophageal symptoms: Assessment by high-resolution manometry. Am J Gastroenterol. 2008;103:2544-2549.
7. Sweis R, Anggiansah A, Wong T, et al. Normative values and inter-observer agreement for liquid and solid bolus swallows in upright and supine positions as assessed by esophageal high-resolution manometry. Neurogastroenterol Motil. 2011; 23:509-e198.
8. Pandolfino JE, Ghosh SK, Rice J, et al. Classifying esophageal motility by pressure topography characteristics: A study of 400 patients and 75 controls. Am J Gastroenterol. 2008;103: 27-37.
9. Kahrilas PJ, Ghosh SK, Pandolfino JE. Esophageal motility disorders in terms of pressure topography: The Chicago Classification. J Clin Gastroenterol. 2008;42:627-635.
10. Pandolfino JE, Fox MR, Bredenoord AJ, et al. Highresolution manometry in clinical practice: Utilizing pressure topography to classify oesophageal motility abnormalities. Neurogastroenterol Motil. 2009;21:796-806.
11. Bansal A, Kahrilas PJ. Has high-resolution manometry changed the approach to esophageal motility disorders? Curr Opin Gastroenterol. 2010;26:344-351.
12. Pandolfino JE, Kwiatek MA, Nealis T, et al. Achalasia: A new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008;135:1526-1533.
13. Salvador R, Costantini M, Zaninotto G, et al. The preoperative manometric pattern predicts the outcome of surgical treatment for esophageal achalasia. J Gastrointest Surg. 2010; 14:1635-1645.
14. Pratap N, Kalapala R, Darisetty S, et al. Achalasia cardia subtyping by high-resolution manometry predicts the therapeutic outcome of pneumatic balloon dilatation. J Neurogastroenterol Motil. 2011;17:48-53.
15. Scherer JR, Kwiatek MA, Soper NJ, et al. Functional esophagogastric junction obstruction with intact peristalsis: A heterogeneous syndrome sometimes akin to achalasia. J Gastrointest Surg. 2009;13:2219-2225.
16. Gyawali CP, Kushnir VM. High-resolution manometric characteristics help differentiate types of distal esophageal obstruction in patients with peristalsis. Neurogastroenterol Motil. 2011;23:502-e197.
17. Porter RF, Gyawali CP. Botulinum toxin injection in dysphagia syndromes with preserved esophageal peristalsis and incomplete lower esophageal sphincter relaxation. Neurogastroenterol Motil. 2011;23:139-144. e27-8.
18. Kwiatek MA, Pandolfino JE, Hirano I, et al. Esophagogastric junction distensibility assessed with an endoscopic functional luminal imaging probe (EndoFLIP). Gastrointest Endosc. 2010;72:272-278.
19. Kwiatek MA, Hirano I, Kahrilas PJ, et al. Mechanical properties of the esophagus in eosinophilic esophagitis. Gastroenterology. 2011;140:82-90.
20. Tutuian R, Mainie I, Agrawal A, et al. Symptom and function heterogenicity among patients with distal esophageal spasm: Studies using combined impedance-manometry. Am J Gastroenterol. 2006;101:464-469.
21. Pandolfino JE, Roman S, Carlson D, et al. Distal esophageal spasm in high-resolution esophageal pressure topography: Defining clinical phenotypes. Gastroenterology. 2011;141:469-475.
22. Behar J, Biancani P. Pathogenesis of simultaneous esophageal contractions in patients with motility disorders. Gastroenterology. 1993;105:111-118.
23. Roman S, Lin Z, Pandolfino JE, et al. Distal contraction latency: A measure of propagation velocity optimized for esophageal pressure topography studies. Am J Gastroenterol. 2011;106:443-451.
24. Tutuian R, Castell DO. Review article: Oesophageal spasm -diagnosis and management. Aliment Pharmacol Ther. 2006;23: 1393-1402.
25. Katz PO, Dalton CB, Richter JE, et al. Esophageal testing of patients with noncardiac chest pain or dysphagia. Results of three years' experience with 1161 patients. Ann Intern Med. 1987;106:593-597.
26. Spechler SJ, Castell DO. Classification of oesophageal motility abnormalities. Gut. 2001;49:145-151.
27. Agrawal A, Hila A, Tutuian R, et al. Clinical relevance of the nutcracker esophagus: Suggested revision of criteria for diagnosis. J Clin Gastroenterol. 2006;40:504-509.
28. Roman S, Pandolfino JE, Chen J, et al. Phenotypes and clinical context of hypercontractility in high-resolution esophageal pressure topography (EPT). Am J Gastroenterol. 2011. [Epub ahead of print].
29. Lacy BE, Weiser K. Esophageal motility disorders: Medical therapy. J Clin Gastroenterol. 2008;42:652-658.
30. Roman S, Lin Z, Kwiatek MA, et al. Weak peristalsis in esophageal pressure topography: Classification and association with Dysphagia. Am J Gastroenterol. 2011;106:349-356.
31. Lazarescu A, Karamanolis G, Aprile L, et al. Perception of dysphagia: Lack of correlation with objective measurements of esophageal function. Neurogastroenterol Motil. 2010;22:1292-1297, e336-e337.
32. Chen CL, Yi CH. Clinical correlates of dysphagia to oesophageal dysmotility: Studies using combined manometry and impedance. Neurogastroenterol Motil. 2008;20:611-617.
33. Richter JE, Barish CF, Castell DO. Abnormal sensory perception in patients with esophageal chest pain. Gastroenterology. 1986;91:845-852.
34. Rao SS, Gregersen H, Hayek B, et al. Unexplained chest pain: The hypersensitive, hyperreactive, and poorly compliant esophagus. Ann Intern Med. 1996;124:950-958.
35. Mujica VR, Mudipalli RS, Rao SS. Pathophysiology of chest pain in patients with nutcracker esophagus. Am J Gastroenterol. 2001;96:1371-1377.
36. Rao SS, Hayek B, Summers RW. Functional chest pain of esophageal origin: Hyperalgesia or motor dysfunction. Am J Gastroenterol. 2001;96:2584-2589.
37. Rao SS, Mudipalli RS, Mujica V, et al. An open-label trial of theophylline for functional chest pain. Dig Dis Sci. 2002;47: 2763-2768.
38. Fass R, Naliboff B, Higa L, et al. Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology. 1998;115:1363-1373.
39. Trimble KC, Pryde A, Heading RC. Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: Avidence for a spectrum of visceral sensitivity in GORD. Gut. 1995;37:7-12.
40. Fass R. Sensory testing of the esophagus. J Clin Gastroenterol. 2004;38:628-641.
41. Mayer EA, Aziz Q, Coen S, et al. Brain imaging approaches to the study of functional GI disorders: A Rome working team report. Neurogastroenterol Motil. 2009;21:579-596.
42. Aziz Q, Andersson JL, Valind S, et al. Identification of human brain loci processing esophageal sensation using positron emission tomography. Gastroenterology. 1997;113:50-59.
43. Aziz Q, Thompson DG. Brain-gut axis in health and disease. Gastroenterology. 1998;114:559-578.
44. Shaker R. Gastroesophageal reflux disease: Beyond mucosal injury. J Clin Gastroenterol. 2007;41(suppl 2):S160-S162.