The impact of Caesarean delivery on paracetamol and ketorolac pharmacokinetics: A paired analysis

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Kulo, Aida ^a   Van Calsteren, Kristel ^a   Verbesselt, Rene ^a   Smits, Anne ^a   Devlieger, Roland ^a   De Hoon, Jan ^a   Allegaert, Karel ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

KETOROLAC TROMETAMOL; PARACETAMOL; PERFUSALGAN; UNCLASSIFIED DRUG; ANALGESIC AGENT; KETOROLAC; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; CESAREAN SECTION; DRUG CLEARANCE; DRUG DISPOSITION; FEMALE; HUMAN; LOADING DRUG DOSE; PUERPERIUM; SINGLE DRUG DOSE; AREA UNDER THE CURVE; COHORT ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; OBSTETRIC ANALGESIA; OBSTETRIC ANESTHESIA; PREGNANCY;

ACETAMINOPHEN; ANALGESIA, OBSTETRICAL; ANALGESICS, NON-NARCOTIC; ANESTHESIA, OBSTETRICAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; CESAREAN SECTION; COHORT STUDIES; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; KETOROLAC; PREGNANCY;

EID: 84862292667     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/437639     Document Type: Article

References (17)

1. Feghali M. N., Mattison D. R., Clinical therapeutics during pregnancy Journal of Biomedicine and Biotechnology 2011 2011 13
2. Anderson G. D., Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach Clinical Pharmacokinetics 2005 44 10 989 1008 (Pubitemid 41356388)
3. Pilari S., Preue C., Huisinga W., Gestational influences on the pharmacokinetics of gestagenic drugs: a combined in silico, in vitro and in vivo analysis European Journal of Pharmaceutical Sciences 2011 42 4 318 331
4. Zajicek A., Giacoia G. P., Obstetric clinical pharmacology: coming of age Clinical Pharmacology and Therapeutics 2007 81 4 481 482 (Pubitemid 46452317)
5. McDonnell N. J., Keating M. L., Muchatuta N. A., Pavy T. J. G., Paech M. J., Analgesia after caesarean delivery Anaesthesia and Intensive Care 2009 37 4 539 551
6. Kulo A., van de Velde M., de Hoon J., Pharmacokinetics of a loading dose of intravenous paracetamol post caesarean delivery International Journal of Obstetric Anaesthesia 2012 21 2 125 128
7. Allegaert K., Anderson B. J., Naulaers G., De Hoon J., Verbesselt R., Debeer A., Devlieger H., Tibboel D., Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates European Journal of Clinical Pharmacology 2004 60 3 191 197 (Pubitemid 38757130)
8. Wang Z., Dsida R. M., Avram M. J., Determination of ketorolac in human plasma by reversed-phase high-performance liquid chromatography using solid-phase extraction and ultraviolet detection Journal of Chromatography B 2001 755 1-2 383 386 (Pubitemid 32324109)
9. Gregoire N., Hovsepian L., Gualano V., Evene E., Dufour G., Gendron A., Safety and pharmacokinetics of paracetamol following intravenous administration of 5 g during the first 24 h with a 2-g starting dose Clinical Pharmacology and Therapeutics 2007 81 3 401 405 (Pubitemid 46371218)
10. Lucker P., Bullingham R., Hooftman L., Lloyd J., Mroszczak E., Tolerability, central effects and pharmacokinetics of intravenous ketorolac tromethamine in volunteers International Journal of Clinical Pharmacology and Therapeutics 1994 32 8 409 414 (Pubitemid 24241641)
11. Jahr J. S., Lee V. K., Intravenous acetaminophen Anesthesiology Clinics 2010 28 4 619 645
12. Miners J. O., Robson R. A., Birkett D. J., Paracetamol metabolism in pregnancy British Journal of Clinical Pharmacology 1986 22 3 359 362 (Pubitemid 17170729)
13. Brocks D. R., Jamali F., Clinical pharmacokinetics of ketorolac tromethamine Clinical Pharmacokinetics 1992 23 6 415 427
14. Knights K. M., Winner L. K., Elliot D. J., Bowalgaha K., Miners J. O., Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs British Journal of Clinical Pharmacology 2009 68 3 402 412
15. Jamali F., Kunz-Dober C. M., Pain-mediated altered absorption and metabolism of ibuprofen: an explanation for decreased serum enantiomer concentration after dental surgery British Journal of Clinical Pharmacology 1999 47 4 391 396 (Pubitemid 29161271)
16. Khalil F., S. Ler S., Physiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development Journal of Biomedicine and Biotechnology 2011 2011 13
17. Allegaert K., Smits A., van den Anker J., Physiologically-based pharmacokinetic modeling in pediatric drug development: a clinicians request for a more integrated approach Journal of Biomedicine and Biotechnology 2012 2012 3