Structure-activity relationship for thiirane-based gelatinase inhibitors

ACS Medicinal Chemistry Letters

Volumn 3, Issue 6, 2012, Pages 490-495

  Lee, Mijoon ^a   Ikejiri, Masahiro ^a   Klimpel, Dennis ^a   Toth, Marta ^a   Espahbodi, Mana ^a   Hesek, Dusan ^a   Forbes, Christopher ^a   Kumarasiri, Malika ^a   Noll, Bruce C ^a   Chang, Mayland ^a   Mobashery, Shahriar ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Gelatinase; matrix metalloproteinases; SAR

Indexed keywords

2 (4 PHENOXYPHENYLSULFONYLMETHYL)THIIRANE; GELATINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; HALF LIFE TIME; HIGH THROUGHPUT SCREENING; KINETICS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

EID: 84862287031     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300050b     Document Type: Article

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