Selective water-soluble gelatinase inhibitor prodrugs

Journal of Medicinal Chemistry

Volumn 54, Issue 19, 2011, Pages 6676-6690

  Gooyit, Major ^a   Lee, Mijoon ^a   Schroeder, Valerie A ^a   Ikejiri, Masahiro ^a   Suckow, Mark A ^a   Mobashery, Shahriar ^a   Chang, Mayland ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; GELATINASE INHIBITOR; ND 322; ND 478; PRODRUG; SB 3CT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; DRUG SOLUBILITY; HUMAN; LIVER MICROSOME; MALE; MOUSE; MUTAGEN TESTING; NONHUMAN; RAT;

AMIDES; ANIMALS; ARGININE; GELATINASES; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; HYDROLYSIS; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; MUTAGENICITY TESTS; PRODRUGS; RATS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; WATER;

EID: 80053920386     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200566e     Document Type: Article

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