Antiviral ability of Kalanchoe gracilis leaf extract against Enterovirus 71 and coxsackievirus A16

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Wang, Ching Ying ^a   Huang, Shun Chueh ^a   Zhang, Yongjun ^b   Lai, Zhen Rung ^a,c   Kung, Szu Hao ^d   Chang, Yuan Shiun ^a   Lin, Cheng Wen ^a,e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b Fujian Center for Disease Control and Prevention   (China)

^c HUNGKUANG UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; FERULIC ACID; KAEMPFEROL; KALANCHOE GRACILIS EXTRACT; PLANT EXTRACT; PROTEINASE; QUERCETIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS A; CYTOTOXICITY; DRUG MECHANISM; ENTEROVIRUS 71; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; KALANCHOE; KALANCHOE GRACILIS; PLANT LEAF; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY; VIRUS REPLICATION;

EID: 84862285713     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/503165     Document Type: Article

References (47)

1. Kao M. C., Handbook of Taiwan Medicinal Plants 1981 Taipei, Taiwan Southern Materials Center
2. Lai Z. R., Peng W. H., Ho Y. L., Huang S. C., Huang T. H., Lai S. C., Ku Y. R., Tsai J. C., Wang C. Y., Chang Y. S., Analgesic and anti-inflammatory activities of the methanol extract of Kalanchoe gracilis (L.) DC stem in mice The American Journal of Chinese Medicine 2010 38 3 529 546
3. Lai Z. R., Ho Y. L., Hung S. C., Antioxidant, anti-inflammatory and antiproliferative activities of Kalanchoe gracilis (L.) DC stem The American Journal of Chinese Medicine 2011 39 6 1275 1290
4. Karin C. S. L., Yang S. L., Roberts M. F., Phillipson J. D., Eupafolin rhamnosides from Kalanchoe gracilis Journal of Natural Products 1989 52 5 970 974
5. Wu P. L., Hsu Y. L., Wu T. S., Bastow K. F., Lee K. H., Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis Organic Letters 2006 8 23 5207 5210 (Pubitemid 44861529)
6. Hwu J. R., Singha R., Hong S. C., Chang Y. H., Das A. R., Vliegen I., De Clercq E., Neyts J., Synthesis of new benzimidazole-coumarin conjugates as anti-hepatitis C virus agents Antiviral Research 2008 77 2 157 162
7. Chiang C. C., Mouscadet J. F., Tsai H. J., Liu C. T., Hsu L. Y., Synthesis and HIV-1 integrase inhibition of novel bis- or tetra-coumarin analogues Chemical and Pharmaceutical Bulletin 2007 55 12 1740 1743
8. Liu M., Cong X. J., Li P., Tan J. J., Chen W. Z., Wang C. X., Study on the inhibitory mechanism and binding mode of the hydroxycoumarin compound NSC158393 to HIV-1 integraseby molecular modeling Biopolymers 2009 91 9 700 709
9. Hwu J. R., Lin S. Y., Tsay S. C., De Clercq E., Leyssen P., Neyts J., Coumarin-purine ribofuranoside conjugates as new agents against hepatitis c virus Journal of Medicinal Chemistry 2011 54 7 2114 2126
10. Ong E. B. B., Watanabe N., Saito A., Futamura Y., Abd El Galil K. H., Koito A., Najimudin N., Osada H., Vipirinin, a coumarin-based HIV-1 Vpr inhibitor, interacts with a hydrophobic region of Vpr Journal of Biological Chemistry 2011 286 16 14049 14056
11. Conti C., Tomao P., Genovese D., Desideri N., Stein M. L., Orsi N., Mechanism of action of the antirhinovirus flavanoid 4′,6-dicyanoflavan Antimicrobial Agents and Chemotherapy 1992 36 1 95 99
12. Conti C., Genovese D., Santoro R., Stein M. L., Orsi N., Fiore L., Activities and mechanisms of action of halogen-substituted flavanoids against poliovirus type 2 infection in vitro Antimicrobial Agents and Chemotherapy 1990 34 3 460 466 (Pubitemid 20068671)
13. Genovese D., Conti C., Tomao P., Desideri N., Stein M. L., Catone S., Fiore L., Effect of chloro-, cyano-, and amidino-substituted flavanoids on enterovirus infection in vitro Antiviral Research 1995 27 1-2 123 136
14. Salvati A. L., De Dominicis A., Tait S., Canitano A., Lahm A., Fiore L., Mechanism of action at the molecular level of the antiviral drug 3(2H)-isoflavene against type 2 poliovirus Antimicrobial Agents and Chemotherapy 2004 48 6 2233 2243 (Pubitemid 38691624)
15. Mothana R. A., Mentel R., Reiss C., Lindequist U., Phytochemical screening and antiviral activity of some medicinal plants from the island Soqotra Phytotherapy Research 2006 20 4 298 302
16. Supratman U., Fujita T., Akiyama K., Hayashi H., Murakami A., Sakai H., Koshimizu K., Ohigashi H., Anti-tumor promoting activity of bufadienolides from Kalanchoe pinnata and K. Daigremontiana tubiflora Bioscience, Biotechnology and Biochemistry 2001 65 4 947 949 (Pubitemid 33614186)
17. Knipe D. N., Howley P. M., Griffin D. E., Enteroviruses: Polioviruses, Coxsackieviruses, Echoviruses, and Newer Enteroviruses. Fields Virology 2007 1 5th. Edited by Pallansch M. A. and Roos R. P
18. Singh S., Chow V. T., Phoon M. C., Chan K. P., Poh C. L., Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers Journal of Clinical Microbiology 2002 40 8 2823 2827 (Pubitemid 35284947)
19. Zeng H., Wen F., Gan Y., Huang W., MRI and associated clinical characteristics of EV71-induced brainstem encephalitis in children with hand-foot-mouth disease. Neuroradiology. In press
20. Sanders S. A., Herrero L. J., McPhie K., Chow S. S. W., Craig M. E., Dwyer D. E., Rawlinson W., McMinn P. C., Molecular epidemiology of enterovirus 71 over two decades in an Australian urban community Archives of Virology 2006 151 5 1003 1013
21. Lin K. H., Hwang K. P., Ke G. M., Wang C. F., Ke L. Y., Hsu Y. T., Tung Y. C., Chu P. Y., Chen B. H., Chen H. L., Kao C. L., Wang J. R., Eng H. L., Wang S. Y., Hsu L. C., Chen H. Y., Evolution of EV71 genogroup in Taiwan from 1998 to 2005: an emerging of subgenogroup C4 of EV71 Journal of Medical Virology 2006 78 2 254 262
22. Yang B., Chuang H., Yang K. D., Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD-1 intestinal cells Virology Journal 2009 6 141 146
23. Chang L. Y., Lin T. Y., Hsu K. H., Huang Y. C., Lin K. L., Hsueh C., Shih S. R., Ning H. C., Hwang M. S., Wang H. S., Lee C. Y., Clinical features and risk factors of pulmonary oedema after enterovirus-71-related hand, foot, and mouth disease The Lancet 1999 354 9191 1682 1686 (Pubitemid 29533058)
24. Ho M., Chen E. R., Hsu K. H., Twu S. J., Chen K. T., Tsai S. F., Wang J. R., Shih S. R., An epidemic of enterovirus 71 infection in Taiwan The New England Journal of Medicine 1999 341 13 929 935 (Pubitemid 29441546)
25. Huang C. C., Liu C. C., Chang Y. C., Chen C. Y., Wang S. T., Yeh T. F., Neurologic complications in children with enterovirus 71 infection The New England Journal of Medicine 1999 341 13 936 942
26. Lin T. Y., Hsia S. H., Huang Y. C., Wu C. T., Chang L. Y., Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous system Clinical Infectious Diseases 2003 36 3 269 274
27. Podin Y., Gias E. L., Ong F., Leong Y. W., Yee S. F., Yusof M. A., Perera D., Teo B., Wee T. Y., Yao S. C., Yao S. K., Kiyu A., Arif M. T., Cardosa M. J., Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years BMC Public Health 2006 6 180 189
28. Yen F. B., Chang L. Y., Kao C. L., Lee P. I., Chen C. M., Lee C. Y., Shao P. L., Wang S. C., Lu C. Y., Huang L. M., Coxsackieviruses infection in northern Taiwanepidemiology and clinical characteristics Journal of Microbiology, Immunology and Infection 2009 42 1 38 46
29. Tsai M. T., Cheng Y. H., Liu Y. N., Liao N. C., Lu W. W., Kung S. H., Real-time monitoring of human enterovirus (HEV)-infected cells and anti-HEV 3C protease potency by fluorescence resonance energy transfer Antimicrobial Agents and Chemotherapy 2009 53 2 748 755
30. Oberste M. S., Pearanda S., Rogers S. L., Henderson E., Nix W. A., Comparative evaluation of Taqman real-time PCR and semi-nested VP1 PCR for detection of enteroviruses in clinical specimens Journal of Clinical Virology 2010 49 1 73 74
31. Castell A., Alvarez E., Carrasco L., The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases Journal of Biomedicine and Biotechnology 2011 2011 23
32. Kuo R. L., Kung S. H., Hsu Y. Y., Liu W. T., Infection with enterovirus 71 or expression of its 24 protease induces apoptotic cell death Journal of General Virology 2002 83 6 1367 1376
33. Ibrahim T., Cunha J. M., Madi K., da Fonseca L. M., Costa S. S., Gonalves Koatz K. V. L., Immunomodulatory and anti-inflammatory effects of Kalanchoe brasiliensis International Immunopharmacology 2002 2 7 875 883 (Pubitemid 34756379)
34. Choi H. J., Song J. H., Park K. S., Baek S. H., In vitro anti-enterovirus 71 activity of gallic acid from Woodfordia fruticosa flowers Letters in Applied Microbiology 2010 50 4 438 440
35. Shih S. R., Tsai K. N., Li Y. S., Chueh C. C., Chan E. C., Inhibition of enterovirus 71-induced apoptosis by allophycocyanin isolated from a blue-green alga Spirulina platensis Journal of Medical Virology 2003 70 1 119 125
36. Zhu Q. C., Wang Y., Liu Y. P., Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin European Journal of Pharmaceutical Sciences 2011 44 3 392 398
37. Lin C. W., Wu C. F., Hsiao N. W., Chang C. Y., Li S. W., Wan L., Lin Y. J., Lin W. Y., Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71 International Journal of Antimicrobial Agents 2008 32 4 355 359
38. Lin T. Y., Liu Y. C., Jheng J. R., Tsai H. P., Jan J. T., Wong W. R., Horng J. T., Anti-enterovirus 71 activity screening of Chinese herbs with anti-infection and inflammation activities American Journal of Chinese Medicine 2009 37 1 143 158
39. Wu B. W., Pan T. L., Leu Y. L., Chang Y. K., Tai P. J., Lin K. H., Horng J. T., Antiviral effects of Salvia miltiorrhiza (Danshen) against enterovirus 71 The American Journal of Chinese Medicine 2007 35 1 153 168
40. Su F. M., Chang J. S., Wang K. C., Tsai J. J., Chiang L. C., A water extract of Pueraria lobata inhibited cytotoxicity of enterovirus 71 in a human foreskin fibroblast cell line Kaohsiung Journal of Medical Sciences 2008 24 10 523 530
41. Kuo K. K., Chang J. S., Wang K. C., Chiang L. C., Water extract of Glycyrrhiza uralensis inhibited enterovirus 71 in a human foreskin fibroblast cell line The American Journal of Chinese Medicine 2009 37 2 383 394
42. Chang L. Y., Huang Y. C., Lin T. Y., Fulminant neurogenic pulmonary oedema with hand, foot, and mouth disease The Lancet 1998 352 9125 367 368
43. Wang S. M., Lei H. Y., Huang K. J., Wu J. M., Wang J. R., Yu C. K., Su I. J., Liu C. C., Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema The Journal of Infectious Diseases 2003 188 4 564 570
44. Wang S. M., Lei H. Y., Su L. Y., Wu J. M., Yu C. K., Wang J. R., Liu C. C., Cerebrospinal fluid cytokines in enterovirus 71 brain stem encephalitis and echovirus meningitis infections of varying severity Clinical Microbiology and Infection 2007 13 7 677 682
45. Lin T. Y., Chang L. Y., Huang Y. C., Hsu K. H., Chiu C. H., Yang K. D., Different proinflammatory reactions in fatal and non-fatal enterovirus 71 infections: implications for early recognition and therapy Acta Paediatrica 2002 91 6 632 635
46. Weng K. F., Chen L. L., Huang P. N., Shih S. R., Neural pathogenesis of enterovirus 71 infection Microbes and Infection 2010 12 7 505 510
47. Khong W. X., Foo D. G., Trasti S. L., Tan E. L., Alonso S., Sustained high levels of interleukin-6 contribute to the pathogenesis of enterovirus 71 in a neonate mouse model Journal of Virology 2011 85 7 3067 3076