A water extract of Pueraria lobata inhibited cytotoxicity of enterovirus 71 in a human foreskin fibroblast cell line

Kaohsiung Journal of Medical Sciences

Volumn 24, Issue 10, 2008, Pages 523-530

  Su, Fu Min ^a,b   Chang, Jung San ^a,c   Wang, Kuo Chih ^b   Tsai, Jih Jin ^a,c   Chiang, Lien Chai ^c  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Chemoprevention; Enterovirus; EV71; Pueraria lobata; Therapy

Indexed keywords

PUERARIA EXTRACT; PUERARIA LOBATA EXTRACT; UNCLASSIFIED DRUG; WATER;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; CYTOTOXICITY TEST; DRUG SELECTIVITY; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; PLANT; PREPUCE; PUERARIA LOBATA; VIRUS ATTACHMENT; VIRUS ENTRY;

EID: 60149092764     PISSN: 1607551X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1607-551X(09)70011-7     Document Type: Article

References (20)

1. Witso E, Palacios G, Cinek O, et al. High prevalence of human enterovirus infections in natural circulation of human enteroviruses. J Clin Microbiol 2006;44: 4095-100.
2. Pallansch MA, Roos RP. Enteroviruses: polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses. In: Knipe DM, Howley PM, Griffin DE, et al., eds. Fields Virology. Philadelphia: Lippincott Williams & Wilkins, 2001:723-75.
3. Wang SM, Liu CC, Tseng HW, et al. Clinical spectrum of enterovirus 71 infection in children in southern Taiwan, with an emphasis on neurological complications. Clin Infect Dis 1999;29:184-90.
4. Ho M, Chen ER, Hsu KH, et al. An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group. N Engl J Med 1999;341: 929-35.
5. Chang LY, Huang LM, Gau SS, et al. Neurodevelopment and cognition in children after enterovirus 71 infection. N Engl J Med 2007;356:1226-34.
6. McMinn PC. An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiol Rev 2002;26:91-107.
7. Li CC, Yang MY, Chen RF, et al. Clinical manifestations and laboratory assessment in an enterovirus 71 outbreak in southern Taiwan. Scand J Infect Dis 2002;34:104-9.
8. Lin CC. Pueraria lobata. In: The Clinical and Application of Crude Drug. Kaohsiung: Fuji Press, 1987:237-9.
9. McGregor NR. Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk. Alcohol 2007;41:469-78.
10. Xu BJ, Zheng YN, Sung CK. Natural medicines for alcoholism treatment: a review. Drug Alcohol Rev 2005; 24:525-36.
11. Lin RC, Li TK. Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats. Am J Clin Nutr 1998; 68:1512S-5S.
12. Yen MH, Lin CC, Chuang CH, et al. Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species. J Ethnopharmacol 1991;34:155-65.
13. Sidwell RW, Huffman JH, Khare GP, et al. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide. Science 1972; 177:705-6.
14. Chiang LC, Chiang W, Chang SF, et al. Characterization of an immortalized human cell line derived from neonatal foreskin diploid fibroblasts. J Dermatol 1992;19:1-11.
15. Chiang LC, Chiang W, Chang MY, et al. Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Res 2002;55:53-62.
16. Chang JS, Wang KC, Chiang LC. Sheng-Ma-Ge-Gen-Tang inhibited enterovirus 71 infection in human foreskin fibroblast cell line. J Ethnopharmacol 2008;119: 104-8.
17. Brown BA, Oberste MS, Alexander JP Jr, et al. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998. J Virol 1999;73: 9969-75.
18. Wang SM, Lei HY, Huang KJ, et al. Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis 2003; 188:564-70.
19. Lin TY, Hsia SH, Huang YC, et al. Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous system. Clin Infect Dis 2003;36:269-74.
20. Wang SM, Lei HY, Huang MC, et al. Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis. J Clin Virol 2006;37:47-52.