The emerging role of PEDF in stem cell biology

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Elahy, Mina ^a   Baindur Hudson, Swati ^a   Dass, Crispin R ^a  

^a VICTORIA UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR; EYE PROTEIN; NERVE GROWTH FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR;

CELL SURVIVAL; CYTOLOGY; EMBRYONIC STEM CELL; GENE OVEREXPRESSION; HUMAN; MESENCHYMAL STEM CELL; NEURAL STEM CELL; NONHUMAN; RETINA STEM CELL; REVIEW; STEM CELL; ANIMAL; PHYSIOLOGY; STEM CELL RESEARCH;

ANIMALS; CELL BIOLOGY; EYE PROTEINS; HUMANS; NERVE GROWTH FACTORS; SERPINS; STEM CELL RESEARCH; STEM CELLS;

EID: 84862275898     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/239091     Document Type: Review

References (42)

1. Xu Z., Fang S., Zuo Y., Zhang Y., Cheng R., Wang Q., Yang Z., Cai W., Ma J., Yang X., Gao G., Combination of pigment epithelium-derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis Cancer Science 2011 102 10 1789 1798
2. Gong Q., Yang X., Cai W., Gao G., Yang Z., Expression and purification of functional epitope of pigment epithelium-derived factor in E. coli with inhibiting effect on endothelial cells Protein Journal 2010 29 3 167 173
3. Olson S. T., Gettins P. G., Regulation of proteases by protein inhibitors of the serpin superfamily Progress in Molecular Biology and Translational Science C 2011 99 185 240
4. Tombran-Tink J., Aparicio S., Xu X., Tink A. R., Lara N., Sawant S., Barnstable C. J., Zhang S. S. M., PEDF and the serpins: phylogeny, sequence conservation, and functional domains Journal of Structural Biology 2005 151 2 130 150 (Pubitemid 41074822)
5. Samkharadze T., Erkan M., Reiser-Erkan C., Demir I. E., Kong B., Ceyhan G. O., Michalski C. W., Esposito I., Friess H., Kleeff J., Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer American Journal of Gastroenterology 2011 106 5 968 980
6. Akiyama T., Dass C. R., Shinoda Y., Kawano H., Tanaka S., Choong P. F. M., PEDF regulates osteoclasts via osteoprotegerin and RANKL Biochemical and Biophysical Research Communications 2010 391 1 789 794
7. Snchez-Snchez F., Aroca-Aguilar J. D., Segura I., Ramrez-Castillejo C., Riese H. H., Coca-Prados M., Escribano J., Expression and purification of functional recombinant human pigment epithelium-derived factor (PEDF) secreted by the yeast Pichia pastoris Journal of Biotechnology 2008 134 1-2 193 201
8. Broadhead M. L., Dass C. R., Choong P. F., In vitro and in vivo biological activity of PEDF against a range of tumors Expert Opinion on Therapeutic Targets 2009 13 12 1429 1438
9. Orgaz J. L., Ladhani O., Hoek K. S., Fernndez-Barral A., Mihic D., Aguilera O., Seftor E. A., Bernad A., Rodrguez-Peralto J. L., Hendrix M. J. C., Volpert O. V., Jiménez B., Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma Oncogene 2009 28 47 4147 4161
10. Yabe T., Wilson D., Schwartz J. P., NF B activation is required for the neuroprotective effects of pigment epithelium-derived Factor (PEDF) on cerebellar granule neurons The Journal of Biological Chemistry 2001 276 46 43313 43319
11. Zaichuk T. A., Shroff E. H., Emmanuel R., Filleur S., Nelius T., Volpert O. V., Nuclear factor of activated T cells balances angiogenesis activation and inhibition Journal of Experimental Medicine 2004 199 11 1513 1522 (Pubitemid 38780406)
12. Ho T. C., Chen S. L., Yang Y. C., Liao C. L., Cheng H. C., Tsao Y. P., PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells Cardiovascular Research 2007 76 2 213 223
13. Dass C. R., Choong P. F. M., uPAR mediates anticancer activity of PEDF Cancer Biology and Therapy 2008 7 8 1262 1270
14. Si Y. L., Zhao Y. L., Hao H. J., Fu X. B., Han W. D., MSCs: biological characteristics, clinical applications and their outstanding concerns Ageing Research Reviews 2011 10 1 93 103
15. Trento C., Dazzi F., Mesenchymal stem cells and innate tolerance: biology and clinical applications. Swiss Medical Weekly 2010 140, article w13121
16. Smith A. G., Embryo-derived stem cells: of mice and men Annual Review of Cell and Developmental Biology 2001 17 435 462 (Pubitemid 33096183)
17. Li L., Xie T., Stem cell niche: structure and function Annual Review of Cell and Developmental Biology 2005 21 605 631 (Pubitemid 41740648)
18. Backly R. M., Cancedda R., Bone marrow stem cells in clinical application: harnessing paracrine roles and niche mechanisms Advances in Biochemical Engineering/Biotechnology 2010 123 265 292
19. Wilson A., Laurenti E., Oser G., van der Wath R. C., Blanco-Bose W., Jaworski M., Offner S., Dunant C. F., Eshkind L., Bockamp E., Li P., MacDonald H. R., Trumpp A., Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair Cell 2008 135 6 1118 1129
20. Yin T., Li L., The stem cell niches in bone The Journal of Clinical Investigation 2006 116 5 1195 1201
21. Reya T., Morrison S. J., Clarke M. F., Weissman I. L., Stem cells, cancer, and cancer stem cells Nature 2001 414 6859 105 111 (Pubitemid 33041634)
22. Anisimov S. V., Christophersen N. S., Correia A. S., Hall V. J., Sandelin I., Li J. Y., Brundin P., Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells Cellular and Molecular Biology Letters 2011 16 1 79 88
23. Zhu D., Deng X., Spee C., Sonoda S., Hsieh C. L., Barron E., Pera M., Hinton D. R., Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival Investigative Ophthalmology and Visual Science 2011 52 3 1573 1585
24. Weiland J. D., Cho A. K., Humayun M. S., Retinal prostheses: current clinical results and future needs Ophthalmology 2010 118 11 2227 2237
25. van Wijngaarden P., Qureshi S. H., Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice Clinical Experimental Optometry 2008 91 5 427 437
26. Pang I. H., Zeng H., Fleenor D. L., Clark A. F., Pigment epithelium-derived factor protects retinal ganglion cells BMC Neuroscience 2007 8, article 11
27. Sarojini H., Estrada R., Lu H., Dekova S., Lee M. J., Gray R. D., Wang E., PEDF from mouse mesenchymal stem cell secretome attracts fibroblasts Journal of Cellular Biochemistry 2008 104 5 1793 1802
28. Fan W., Crawford R., Xiao Y., The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization Differentiation 2011 81 3 181 191
29. Otsu K., Das S., Houser S. D., Quadri S. K., Bhattacharya S., Bhattacharya J., Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells Blood 2009 113 18 4197 4205
30. Tombran-Tink J., Barnstable C. J., Osteoblasts and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: Possible mediators of angiogenesis and matrix remodeling in the bone Biochemical and Biophysical Research Communications 2004 316 2 573 579 (Pubitemid 38338629)
31. Chiellini C., Cochet O., Negroni L., Samson M., Poggi M., Ailhaud G., Alessi M. C., Dani C., Amri E. Z., Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation BMC Molecular Biology 2008 9 26
32. Quan G. M. Y., Ojaimi J., Li Y., Kartsogiannis V., Zhou H., Choong P. F. M., Localization of pigment epithelium-derived factor in growing mouse bone Calcified Tissue International 2005 76 2 146 153 (Pubitemid 40684962)
33. Ramrez-Castillejo C., Snchez-Snchez F., Andreu-Agull C., Ferrn S. R., Aroca-Aguilar J. D., Snchez P., Mira H., Escribano J., Farias I., Pigment epithelium-derived factor is a niche signal for neural stem cell renewal Nature Neuroscience 2006 9 3 331 339 (Pubitemid 43290962)
34. Mirochnik Y., Aurora A., Schulze-Hoepfner F. T., Deabes A., Shifrin V., Beckmann R., Polsky C., Volpert O. V., Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth Clinical Cancer Research 2009 15 5 1655 1663
35. Andreu-Agull C., Morante-Redolat J. M., Delgado A. C., Farias I., Vascular niche factor PEDF modulates notch-dependent stemness in the adult subependymal zone Nature Neuroscience 2009 12 12 1514 1523
36. Joo Y. O., Mee K. K., Mi S. S., Hyun J. L., Jung H. K., Won R. W., Jin H. L., The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury Stem Cells 2008 26 4 1047 1055
37. Hou H. Y., Liang H. L., Wang Y. S., Zhang Z. X., Wang B. R., Shi Y. Y., Dong X., Cai Y., A therapeutic strategy for choroidal neovascularization based on recruitment of mesenchymal stem cells to the sites of lesions Molecular Therapy 2010 18 10 1837 1845
38. Tong J. P., Yao Y. F., Contribution of VEGF and PEDF to choroidal angiogenesis: a need for balanced expressions Clinical Biochemistry 2006 39 3 267 276
39. Apte R. S., Barreiro R. A., Duh E., Volpert O., Ferguson T. A., Stimulation of neovascularization by the anti-angiogenic factor PEDF Investigative Ophthalmology and Visual Science 2004 45 12 4491 4497 (Pubitemid 39564676)
40. Arnhold S., Heiduschka P., Klein H., Absenger Y., Basnaoglu S., Kreppel F., Renke-Fahle S., Kochanek S., Bartz-Schmidt K. U., Addicks K., Schraermeyer U., Adenovirally transduced bone marrow stromal cells differentiate into pigment epithelial cells and induce rescue effects in RCS rats Investigative Ophthalmology and Visual Science 2006 47 9 4121 4129 (Pubitemid 46044331)
41. Passier R., van Laake L. W., Mummery C. L., Stem-cell-based therapy and lessons from the heart Nature 2008 453 7193 322 329 (Pubitemid 351693138)
42. Liang H., Hou H., Yi W., Increased expression of pigment epithelium-derivedfactor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury. European Heart Journal. In press