Insulin-like growth factor 1 and a cytosolic tyrosine kinase activate chloride outward transport during maturation of hippocampal neurons

Journal of Neuroscience

Volumn 21, Issue 21, 2001, Pages 8339-8347

  Kelsch, Wolfgang ^a   Hormuzdi, Sheriar ^a   Straube, Emine ^a   Lewen, Andrea ^a   Monyer, Hannah ^a   Misgeld, Ulrich ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Development; Furosemide; GABAA; Genistein; Hippocampus; IGF 1; KCC2; Tyrosine kinase

Indexed keywords

4 AMINOBUTYRIC ACID; CARRIER PROTEIN; CHLORIDE ION; FUROSEMIDE; GENISTEIN; KCC2 PROTEIN; POTASSIUM ION; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYTOSOL; EMBRYO; FEMALE; GABAERGIC TRANSMISSION; HIPPOCAMPUS; HYPERPOLARIZATION; METABOLIC INHIBITION; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035503062     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-21-08339.2001     Document Type: Article

References (43)

1. Genistein, a specific inhibitor of tyrosine-specific protein kinase
2. Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development
3. Giant synaptic potentials in immature rat CA3 hippocampal neurones
4. Potentiation of neuronal L calcium channels by IGF-1 requires phosphorylation of the α1 subunit on a specific tyrosine residue
5. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro
6. Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro
7. Tyrosine kinase-dependent selection of transmitter responses induced by neuronal contact
8. GABA: An excitatory transmitter in early postnatal life
9. Insulin is released from rat brain neuronal cells in culture
10. - cotransporter in rat neocortex
11. Deficiency of Src family kinases Fgr and Hck results in activation of erythrocyte K-Cl-cotransport
12. Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons
13. - regulation
14. GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
15. Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early postsynaptic inhibition
16. On the inhibitory actions of baclofen and γ-aminobutyric acid in rat ventral midbrain culture
17. B receptor-mediated inhibition of tetrodotoxin-resistant GABA release in rodent hippocampal CA1 pyramidal cells
18. Role of chloride-homeostasis in the inhibitory control of neuronal network oscillators
19. - accumulation and depletion in cultured rat midbrain neurons
20. A receptor-mediated IPSPs in rat neocortical neurons
21. Regulation of intracellular chloride by cotransporters in lateral superior olive neurons
22. 125I}insulin receptor binding sites in developing and adult rat brain
23. Developmental regulation of the neuronal-specific isoform of K-Cl cotransporter KCC2 in postnatal rat brain
24. The role of chloride transport in postsynaptic inhibition of hippocampal neurons
25. mRNAS for one, two or three members of trk receptor family are expressed in single rat trigeminal ganglion neurons
26. A receptors by tyrosine phosphorylation
27. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
28. o regulation
29. Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform
30. Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by Src
31. Different localizations and functions of L-type and N-type calcium channels during development of hippocampal neurons
32. - cotransporter KCC2 renders GABA hyperpolarizing during neuronal maturation
33. Sodium-potassium-chloride cotransport
34. A role for Src kinase in spontaneous epileptic activity in the CA3 region of the hippocampus
35. Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis
36. Differential expression of an inwardly rectifying chloride conductance in rat brain neurons: A potential mechanism for cell-specific modulation of postsynaptic inhibition
37. Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue
38. Outward chloride/cation cotransport in mammalian cortical neurons
39. A receptor function by tyrosine phosphorylation of β subunits
40. A receptors to postsynaptic domains by insulin
41. Release of immunoreactive insulin from rat brain synaptosomes under depolarizing conditions
42. The neuron-specific K-Cl cotransporter, KCC2. Antibody development and initial characterization of the protein
43. Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate reeptors