-
1
-
-
0014767029
-
Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radiographic, and cytogenetic studies
-
Biedler JL, Riehm H. Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radiographic, and cytogenetic studies. Cancer Res 1970; 30: 1174-1184.
-
(1970)
Cancer Res
, vol.30
, pp. 1174-1184
-
-
Biedler, J.L.1
Riehm, H.2
-
2
-
-
39749084704
-
Development of inhibitors of ATP-binding cassette drug transporters: Present status and challenges
-
Shukla S, Wu CP, Ambudkar SV. Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges. Expert Opin Drug Metab Toxicol 2008; 4: 205-223.
-
(2008)
Expert Opin Drug Metab Toxicol
, vol.4
, pp. 205-223
-
-
Shukla, S.1
Wu, C.P.2
Ambudkar, S.V.3
-
3
-
-
28944436711
-
Microtubule targeting agents: Basic mechanisms of multidrug resistance (MDR)
-
Fojo AT, Menefee M. Microtubule targeting agents: basic mechanisms of multidrug resistance (MDR). Semin Oncol 2005; 32: S3-S8.
-
(2005)
Semin Oncol
, vol.32
-
-
Fojo, A.T.1
Menefee, M.2
-
4
-
-
41549119415
-
Strategies to overcome or circumvent P-glycoprotein mediated multidrug resistance
-
Yuan H, Li X, Wu J, Li J, Qu X, Xu W, et al. Strategies to overcome or circumvent P-glycoprotein mediated multidrug resistance. Curr Med Chem 2008; 15: 470-476.
-
(2008)
Curr Med Chem
, vol.15
, pp. 470-476
-
-
Yuan, H.1
Li, X.2
Wu, J.3
Li, J.4
Qu, X.5
Xu, W.6
-
6
-
-
34247854842
-
Efficacy of chemotherapeutic agents under hypoxic conditions in pulmonary adenocarcinoma multidrug resistant cell line
-
Shicang Y, Guijun H, Guisheng Q, Yuying L, Guoming W, Ruiling G Efficacy of chemotherapeutic agents under hypoxic conditions in pulmonary adenocarcinoma multidrug resistant cell line. J Chemother 2007; 19: 203-211.
-
(2007)
J Chemother
, vol.19
, pp. 203-211
-
-
Shicang, Y.1
Guijun, H.2
Guisheng, Q.3
Yuying, L.4
Guoming, W.5
Ruiling, G.6
-
7
-
-
0036685248
-
Integrins and extracellular matrix: A novel mechanism of multidrug resistance
-
Elliott T, Sethi T. Integrins and extracellular matrix: a novel mechanism of multidrug resistance. Expert Rev Anticancer Ther 2002; 2: 449-459.
-
(2002)
Expert Rev Anticancer Ther
, vol.2
, pp. 449-459
-
-
Elliott, T.1
Sethi, T.2
-
8
-
-
0036432994
-
Hypoxia-induced angiogenesis in human hepatocellular carcinoma
-
Kim KR, Moon HE, Kim KW. Hypoxia-induced angiogenesis in human hepatocellular carcinoma. J Mol Med 2002; 80: 703-714.
-
(2002)
J Mol Med
, vol.80
, pp. 703-714
-
-
Kim, K.R.1
Moon, H.E.2
Kim, K.W.3
-
9
-
-
84862252568
-
Multidrug resistance induced by hypoxia in hepatocellular carcinoma
-
Zhu H, Luo SF, Guan J, Zhang WG, Zhang BX, Chen XP Multidrug resistance induced by hypoxia in hepatocellular carcinoma. J Hepatol 2004; 40 Suppl 1: 105-106.
-
(2004)
J Hepatol
, vol.40
, Issue.SUPPL. 1
, pp. 105-106
-
-
Zhu, H.1
Luo, S.F.2
Guan, J.3
Zhang, W.G.4
Zhang, B.X.5
Chen, X.P.6
-
10
-
-
84862262052
-
Formation of multidrug resistance of hepatocellular carcinoma induced by microenvironment and its mechanism
-
Zhu H, Chen XP, Luo SF, Guan J, Zhang WG, Zhang BX. Formation of multidrug resistance of hepatocellular carcinoma induced by microenvironment and its mechanism. China J Exp Surg (Chin) 2005; 22: 1315-1318.
-
(2005)
China J Exp Surg (Chin)
, vol.22
, pp. 1315-1318
-
-
Zhu, H.1
Chen, X.P.2
Luo, S.F.3
Guan, J.4
Zhang, W.G.5
Zhang, B.X.6
-
11
-
-
9244242522
-
Involvement of extracellular signal-regulated kinase/ mitogen-activated protein kinase pathway in multidrug resistance induced by HBx in hepatoma cell line
-
Guan J, Chen XP, Zhu H, Luo SF, Cao B, Ding L. Involvement of extracellular signal-regulated kinase/ mitogen-activated protein kinase pathway in multidrug resistance induced by HBx in hepatoma cell line. World J Gastroenterol 2004; 10: 3522-3527.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3522-3527
-
-
Guan, J.1
Chen, X.P.2
Zhu, H.3
Luo, S.F.4
Cao, B.5
Ding, L.6
-
12
-
-
33745953930
-
Role of hypoxia-inducible factor-1-a in formation of multidrug resistance induced by microenvironment in hepatocellular carcinoma
-
Luo SF, Chen XP, Zhu H, Zhang BX, Guan J. Role of hypoxia-inducible factor-1-a in formation of multidrug resistance induced by microenvironment in hepatocellular carcinoma. Chin-Ge J Clin Oncol 2006; 5: 178-183.
-
(2006)
Chin-Ge J Clin Oncol
, vol.5
, pp. 178-183
-
-
Luo, S.F.1
Chen, X.P.2
Zhu, H.3
Zhang, B.X.4
Guan, J.5
-
13
-
-
31344462626
-
Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells
-
Zhu H, Chen XP, Luo SF, Guan J, Zhang WG, Zhang BX. Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells. J Exp Clin Cancer Res 2005; 24: 565-574.
-
(2005)
J Exp Clin Cancer Res
, vol.24
, pp. 565-574
-
-
Zhu, H.1
Chen, X.P.2
Luo, S.F.3
Guan, J.4
Zhang, W.G.5
Zhang, B.X.6
-
14
-
-
33846441666
-
Hypoxia-inducible factor-1a-dependent expression and significance of the related multidrug resistance genes induced by hypoxia in human hepatocarcinoma cell
-
Chin
-
Zhu H, Chen XP, Luo SF, Guan J, Zhang WG, Zhang BX, et al. Hypoxia-inducible factor-1a-dependent expression and significance of the related multidrug resistance genes induced by hypoxia in human hepatocarcinoma cell. Chin J Surg (Chin) 2005; 43: 277-281.
-
(2005)
Chin J Surg
, vol.43
, pp. 277-281
-
-
Zhu, H.1
Chen, X.P.2
Luo, S.F.3
Guan, J.4
Zhang, W.G.5
Zhang, B.X.6
-
15
-
-
54049145982
-
The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma
-
Chin
-
Zhu H, Chen XP, Luo SF, Guan J, Zhang WG, Zhang BX, et al. The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma. Chin J Surg (Chin) 2007; 45: 917-920.
-
(2007)
Chin J Surg
, vol.45
, pp. 917-920
-
-
Zhu, H.1
Chen, X.P.2
Luo, S.F.3
Guan, J.4
Zhang, W.G.5
Zhang, B.X.6
-
17
-
-
79954531754
-
Effects of aging on time course of neovascularization-related gene expression following acute hindlimb ischemia in mice
-
Wang JS, Liu X, Xue ZY, Alderman L, Tilan JU, Adenika R, et al. Effects of aging on time course of neovascularization-related gene expression following acute hindlimb ischemia in mice. Chin Med J 2011; 124: 1075-1081.
-
(2011)
Chin Med J
, vol.124
, pp. 1075-1081
-
-
Wang, J.S.1
Liu, X.2
Xue, Z.Y.3
Alderman, L.4
Tilan, J.U.5
Adenika, R.6
-
19
-
-
34248179635
-
Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1alpha
-
Kim HJ, Chung H, Yoo YG, Kim H, Lee JY, Lee MO, et al. Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1alpha. Mol Cancer Res 2007; 5: 321-329.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 321-329
-
-
Kim, H.J.1
Chung, H.2
Yoo, Y.G.3
Kim, H.4
Lee, J.Y.5
Lee, M.O.6
-
20
-
-
62749102772
-
Effect of endothelial PAS domain protein 1 and hypoxia inducible factor 1alpha on vascular endothelial growth factor expression in human pancreatic carcinoma
-
Zhu DM, Li DC, Zhang ZX, Zhang XY Effect of endothelial PAS domain protein 1 and hypoxia inducible factor 1alpha on vascular endothelial growth factor expression in human pancreatic carcinoma. Chin Med J 2008; 121: 2258-2264.
-
(2008)
Chin Med J
, vol.121
, pp. 2258-2264
-
-
Zhu, D.M.1
Li, D.C.2
Zhang, Z.X.3
Zhang, X.Y.4
-
21
-
-
0037096732
-
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
-
Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res 2002; 62: 3387-3394.
-
(2002)
Cancer Res
, vol.62
, pp. 3387-3394
-
-
Comerford, K.M.1
Wallace, T.J.2
Karhausen, J.3
Louis, N.A.4
Montalto, M.C.5
Colgan, S.P.6
-
22
-
-
0037365537
-
Regulation of the multidrug resistance transporter p-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species
-
Wartenberg M, Ling FC, Muschen M, Klein F, Acker H, Gassmann M, et al. Regulation of the multidrug resistance transporter p-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB J 2003; 17: 503-505.
-
(2003)
FASEB J
, vol.17
, pp. 503-505
-
-
Wartenberg, M.1
Ling, F.C.2
Muschen, M.3
Klein, F.4
Acker, H.5
Gassmann, M.6
-
23
-
-
0033981845
-
Erk activation upon hypoxia: Involvement in HIF-1 activation
-
Minet E, Arnould T, Michel G, Roland I, Mottet D, Raes M, et al. Erk activation upon hypoxia: involvement in HIF-1 activation. FEBS Lett 2000; 468: 53-58.
-
(2000)
FEBS Lett
, vol.468
, pp. 53-58
-
-
Minet, E.1
Arnould, T.2
Michel, G.3
Roland, I.4
Mottet, D.5
Raes, M.6
-
24
-
-
0035478294
-
Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation
-
Minet E, Mchel G, Mottet D, Raes M, Mchiels C. Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation. Free Radic Biol Med 2001; 31: 847-855.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 847-855
-
-
Minet, E.1
McHel, G.2
Mottet, D.3
Raes, M.4
McHiels, C.5
-
25
-
-
7544220200
-
The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha
-
Yoo YG, Cho S, Park S, Lee MO. The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha. FEBS Lett 2004; 577: 121-126.
-
(2004)
FEBS Lett
, vol.577
, pp. 121-126
-
-
Yoo, Y.G.1
Cho, S.2
Park, S.3
Lee, M.O.4
-
26
-
-
35248814408
-
The role of hypoxia-inducible factors in cancer
-
Maynard MA, Ohh M. The role of hypoxia-inducible factors in cancer. Cell Mol Life Sci 2007; 64: 2170-2180.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2170-2180
-
-
Maynard, M.A.1
Ohh, M.2
-
27
-
-
0037337061
-
The subtle side to hypoxia inducible factor (hifalpha) regulation
-
Bilton RL, Booker GW The subtle side to hypoxia inducible factor (hifalpha) regulation. Eur J Biochem 2003; 270: 791-798.
-
(2003)
Eur J Biochem
, vol.270
, pp. 791-798
-
-
Bilton, R.L.1
Booker, G.W.2
-
28
-
-
36949007159
-
Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha
-
Lu Y, Liang K, Li X, Fan Z. Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha. Mol Cancer 2007; 6: 63.
-
(2007)
Mol Cancer
, vol.6
, pp. 63
-
-
Lu, Y.1
Liang, K.2
Li, X.3
Fan, Z.4
-
29
-
-
34547662090
-
Basic FGF augments hypoxia induced HIF-1-alpha expression and VEGF release in t47d breast cancer cells
-
Shi YH, Bingle L, Gong LH, Wang YX, Corke KP, Fang WG. Basic FGF augments hypoxia induced HIF-1-alpha expression and VEGF release in t47d breast cancer cells. Pathology 2007; 39: 396-400.
-
(2007)
Pathology
, vol.39
, pp. 396-400
-
-
Shi, Y.H.1
Bingle, L.2
Gong, L.H.3
Wang, Y.X.4
Corke, K.P.5
Fang, W.G.6
-
30
-
-
0036139795
-
HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: Role of map kinases
-
Mchiels C, Minet E, Michel G, Mottet D, Piret JP, Raes M. HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of map kinases. IUBMB Life 2001; 52: 49-53.
-
(2001)
IUBMB Life
, vol.52
, pp. 49-53
-
-
McHiels, C.1
Minet, E.2
Michel, G.3
Mottet, D.4
Piret, J.P.5
Raes, M.6
-
31
-
-
0037211301
-
Role of erk and calcium in the hypoxia-induced activation of HIF-1
-
Mottet D, Mchel G, Renard P, Ninane N, Raes M, Mchiels C. Role of erk and calcium in the hypoxia-induced activation of HIF-1. J Cell Physiol 2003; 194: 30-44.
-
(2003)
J Cell Physiol
, vol.194
, pp. 30-44
-
-
Mottet, D.1
McHel, G.2
Renard, P.3
Ninane, N.4
Raes, M.5
McHiels, C.6
-
32
-
-
0031038419
-
Complex role of protein phosphorylation in gene activation by hypoxia
-
Salceda S, Beck I, Srinivas V, Caro J. Complex role of protein phosphorylation in gene activation by hypoxia. Kidney Int 1997; 51: 556-559.
-
(1997)
Kidney Int
, vol.51
, pp. 556-559
-
-
Salceda, S.1
Beck, I.2
Srinivas, V.3
Caro, J.4
-
33
-
-
0037201947
-
The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade
-
Andresen BT, Rizzo MA, Shome K, Romero G The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade. FEBS Lett 2002; 531: 65-68.
-
(2002)
FEBS Lett
, vol.531
, pp. 65-68
-
-
Andresen, B.T.1
Rizzo, M.A.2
Shome, K.3
Romero, G.4
-
34
-
-
0025290163
-
An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control
-
Boulton TG, Yancopoulos GD, Gregory JS, Slauqhter C, Moomaw C, Hsu J, et al. An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. Science 1990; 249: 64-67.
-
(1990)
Science
, vol.249
, pp. 64-67
-
-
Boulton, T.G.1
Yancopoulos, G.D.2
Gregory, J.S.3
Slauqhter, C.4
Moomaw, C.5
Hsu, J.6
-
35
-
-
34447321311
-
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of p-glycoprotein
-
Katayama K, Yoshioka S, Tsukahara S, Mtsuhashi J, Sugimoto Y Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of p-glycoprotein. Mol Cancer Ther 2007; 6: 2092-2102.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2092-2102
-
-
Katayama, K.1
Yoshioka, S.2
Tsukahara, S.3
Mtsuhashi, J.4
Sugimoto, Y.5
-
36
-
-
40649085141
-
The multidrug transporter p-glycoprotein: A mediator of melanoma invasion?
-
Colone M, Calcabrini A, Toccacieli L, Bozzuto G, Strinqaro A, Gentile M, et al. The multidrug transporter p-glycoprotein: a mediator of melanoma invasion? J Invest Dermatol 2008; 128: 957-971.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 957-971
-
-
Colone, M.1
Calcabrini, A.2
Toccacieli, L.3
Bozzuto, G.4
Strinqaro, A.5
Gentile, M.6
-
37
-
-
0032538797
-
Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha
-
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, et al. Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha. EMBO J 1998; 17: 6573-6586.
-
(1998)
EMBO J
, vol.17
, pp. 6573-6586
-
-
Kallio, P.J.1
Okamoto, K.2
O'Brien, S.3
Carrero, P.4
Makino, Y.5
Tanaka, H.6
-
38
-
-
33845403070
-
Identification of mapk phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha
-
Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, et al. Identification of mapk phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J Biol Chem 2006; 281: 33095-33106.
-
(2006)
J Biol Chem
, vol.281
, pp. 33095-33106
-
-
Mylonis, I.1
Chachami, G.2
Samiotaki, M.3
Panayotou, G.4
Paraskeva, E.5
Kalousi, A.6
-
39
-
-
38649134482
-
Flavonoids induce HIF-1alpha but impair its nuclear accumulation and activity
-
Triantafyllou A, Mylonis I, Simos G, Bonanou S, Tsakalof A. Flavonoids induce HIF-1alpha but impair its nuclear accumulation and activity. Free Radic Biol Med 2008; 44: 657-670.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 657-670
-
-
Triantafyllou, A.1
Mylonis, I.2
Simos, G.3
Bonanou, S.4
Tsakalof, A.5
-
40
-
-
39149098464
-
Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin alpha/beta pathway
-
Depping R, Steinhoff A, Schindler SG, Friedrich B, Faqerlund R Metzen E, et al. Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway. Biochim Biophys Acta 2008; 1783: 394-404.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 394-404
-
-
Depping, R.1
Steinhoff, A.2
Schindler, S.G.3
Friedrich, B.4
Faqerlund, R.5
Metzen, E.6
-
41
-
-
0032725554
-
P42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
-
Richard DE, Berra E, Gothie E, Roux D, Pouyssegur J. P42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J Biol Chem 1999; 274: 32631-32637.
-
(1999)
J Biol Chem
, vol.274
, pp. 32631-32637
-
-
Richard, D.E.1
Berra, E.2
Gothie, E.3
Roux, D.4
Pouyssegur, J.5
|