Hypofractionated image-guided breath-hold SABR (Stereotactic Ablative Body Radiotherapy) of liver metastases - clinical results

Radiation Oncology

Volumn 7, Issue 1, 2012, Pages

  Boda Heggemann, Judit ^a   Dinter, Dietmar ^a   Weiss, Christel ^a   Frauenfeld, Anian ^a   Siebenlist, Kerstin ^a   Attenberger, Ulrike ^a   Ottstadt, Martine ^a   Schneider, Frank ^a   Hofheinz, Ralf Dieter ^a   Wenz, Frederik ^a   Lohr, Frank ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Hypofractionated image guided breath hold SABR; Liver metastases; Local control; Survival; Toxicity

Indexed keywords

ALKALINE PHOSPHATASE; BILIRUBIN; C REACTIVE PROTEIN; CHOLINESTERASE;

ABDOMINAL PAIN; ABLATION THERAPY; ADULT; AGED; ANOREXIA; ARTICLE; CANCER SURVIVAL; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FATIGUE; FEMALE; FEVER; FOLLOW UP; GASTROINTESTINAL HEMORRHAGE; HUMAN; HUMAN TISSUE; IMAGE GUIDED RADIOTHERAPY; LIVER METASTASIS; MALE; NAUSEA; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION INJURY; RETROSPECTIVE STUDY; STEREOTACTIC BODY RADIATION THERAPY; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; BREATH HOLDING; CARCINOMA; COHORT STUDIES; DOSE FRACTIONATION; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RADIOSURGERY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, IMAGE-GUIDED; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84862266725     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-7-92     Document Type: Article

References (33)

1. Timmerman RD, Bizekis CS, Pass HI, et al. Local surgical, ablative, and radiation treatment of metastases. CA Cancer J Clin 2009, 59:145-170. 10.3322/caac.20013, 19364702.
2. Blomgren H, Lax I, Naslund I, Svanstrom R. Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator. Clinical experience of the first thirty-one patients. Acta Oncol 1995, 34:861-870. 10.3109/02841869509127197, 7576756.
3. Herfarth KK, Debus J, Lohr F, et al. Stereotactic single-dose radiation therapy of liver tumors: results of a phase I/II trial. J Clin Oncol 2001, 19:164-170.
4. Kavanagh BD, Schefter TE, Cardenes HR, et al. Interim analysis of a prospective phase I/II trial of SBRT for liver metastases. Acta Oncol 2006, 45:848-855. 10.1080/02841860600904870, 16982549.
5. McCammon R, Schefter TE, Gaspar LE, Zaemisch R, Gravdahl D, Kavanagh B. Observation of a dose-control relationship for lung and liver tumors after stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 2009, 73:112-118. 10.1016/j.ijrobp.2008.03.062, 18786780.
6. Milano MT, Constine LS, Okunieff P. Normal tissue toxicity after small field hypofractionated stereotactic body radiation. Radiat Oncol 2008, 3:36. 10.1186/1748-717X-3-36, 2596155, 18976463.
7. Guckenberger M, Sweeney RA, Wilbert J, et al. Image-guided radiotherapy for liver cancer using respiratory-correlated computed tomography and cone-beam computed tomography. Int J Radiat Oncol Biol Phys 2008, 71:297-304. 10.1016/j.ijrobp.2008.01.005, 18406894.
8. Wong JW, Sharpe MB, Jaffray DA, et al. The use of active breathing control (ABC) to reduce margin for breathing motion. Int J Radiat Oncol Biol Phys 1999, 44:911-919. 10.1016/S0360-3016(99)00056-5, 10386650.
9. Dawson LA, Eccles C, Bissonnette JP, Brock KK. Accuracy of daily image guidance for hypofractionated liver radiotherapy with active breathing control. Int J Radiat Oncol Biol Phys 2005, 62:1247-1252. 10.1016/j.ijrobp.2005.03.072, 15990028.
10. Fuss M, Salter BJ, Cavanaugh SX, et al. Daily ultrasound-based image-guided targeting for radiotherapy of upper abdominal malignancies. Int J Radiat Oncol Biol Phys 2004, 59:1245-1256. 10.1016/j.ijrobp.2003.12.030, 15234062.
11. Boda-Heggemann J, Mennemeyer P, Wertz H, et al. Accuracy of ultrasound-based image guidance for daily positioning of the upper abdomen: an online comparison with cone beam CT. Int J Radiat Oncol Biol Phys 2009, 74:892-897. 10.1016/j.ijrobp.2009.01.061, 19394160.
12. Boda-Heggemann J, Walter C, Mai S, et al. Frameless stereotactic radiosurgery of a solitary liver metastasis using active breathing control and stereotactic ultrasound. Strahlenther Onkol 2006, 182:216-221. 10.1007/s00066-006-1453-8, 16622623.
13. Boda-Heggemann J, Lohr F, Wenz F, Flentje M, Guckenberger M. kV cone-beam CT-based IGRT: a clinical review. Strahlenther Onkol 2011, 187:284-291. 10.1007/s00066-011-2236-4, 21533757.
14. Boda-Heggemann J, Fleckenstein J, Lohr F, et al. Multiple breath-hold CBCT for online image guided radiotherapy of lung tumors: simulation with a dynamic phantom and first patient data. Radiother Oncol 2011, 98:309-316. 10.1016/j.radonc.2011.01.019, 21345509.
15. Koshani R, Balter JM, Hayman JA, Henning GT, van Herk M. Short-term and long-term reproducibility of lung tumor position using active breathing control (ABC). Int J Radiat Oncol Biol Phys 2006, 65:1553-1559. 10.1016/j.ijrobp.2006.04.027, 16863932.
16. Eccles CL, Bissonnette JP, Craig T, Taremi M, Wu X, Dawson LA. Treatment planning study to determine potential benefit of intensity-modulated radiotherapy versus conformal radiotherapy for unresectable hepatic malignancies. Int J Radiat Oncol Biol Phys 2008, 72:582-588. 10.1016/j.ijrobp.2008.06.1496, 18793961.
17. Boda-Heggemann J, Kohler FM, Kupper B, et al. Accuracy of ultrasound-based (BAT) prostate-repositioning: a three-dimensional on-line fiducial-based assessment with cone-beam computed tomography. Int J Radiat Oncol Biol Phys 2008, 70:1247-1255. 10.1016/j.ijrobp.2007.12.003, 18313531.
18. Molinelli S, de Pooter J, Mendez Romero A, et al. Simultaneous tumour dose escalation and liver sparing in Stereotactic Body Radiation Therapy (SBRT) for liver tumours due to CTV-to-PTV margin reduction. Radiother Oncol 2008, 87:432-438. 10.1016/j.radonc.2007.11.015, 18077033.
19. Case RB, Sonke JJ, Moseley DJ, Kim J, Brock KK, Dawson LA. Inter- and intrafraction variability in liver position in non-breath-hold stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2009, 75:302-308. 10.1016/j.ijrobp.2009.03.058, 19628342.
20. Dawson LA, Ten Haken RK. Partial volume tolerance of the liver to radiation. Semin Radiat Oncol 2005, 15:279-283. 10.1016/j.semradonc.2005.04.005, 16183482.
21. Katz AW, Carey-Sampson M, Muhs AG, Milano MT, Schell MC, Okunieff P. Hypofractionated stereotactic body radiation therapy (SBRT) for limited hepatic metastases. Int J Radiat Oncol Biol Phys 2007, 67:793-798. 10.1016/j.ijrobp.2006.10.025, 17197128.
22. Milano MT, Katz AW, Schell MC, Philip A, Okunieff P. Descriptive analysis of oligometastatic lesions treated with curative-intent stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2008, 72:1516-1522. 10.1016/j.ijrobp.2008.03.044, 18495378.
23. Goodman KA, Wiegner EA, Maturen KE, et al. Dose-escalation study of single-fraction stereotactic body radiotherapy for liver malignancies. Int J Radiat Oncol Biol Phys 2010, 78:486-493. 10.1016/j.ijrobp.2009.08.020, 20350791.
24. Iwata H, Shibamoto Y, Hashizume C, et al. Hypofractionated stereotactic body radiotherapy for primary and metastatic liver tumors using the novalis image-guided system: preliminary results regarding efficacy and toxicity. Technol Cancer Res Treat 2010, 9:619-627.
25. Rusthoven KE, Kavanagh BD, Cardenes H, et al. Multi-institutional phase I/II trial of stereotactic body radiation therapy for liver metastases. J Clin Oncol 2009, 27:1572-1578. 10.1200/JCO.2008.19.6329, 19255321.
26. Lee MT, Kim JJ, Dinniwell R, et al. Phase I study of individualized stereotactic body radiotherapy of liver metastases. J Clin Oncol 2009, 27:1585-1591. 10.1200/JCO.2008.20.0600, 19255313.
27. Hsu A, Miller NR, Evans PM, Bamber JC, Webb S. Feasibility of using ultrasound for real-time tracking during radiotherapy. Med Phys 2005, 32:1500-1512. 10.1118/1.1915934, 16013706.
28. Fowler JF, Tome WA, Fenwick JD, Mehta MP. A challenge to traditional radiation oncology. Int J Radiat Oncol Biol Phys 2004, 60:1241-1256. 10.1016/j.ijrobp.2004.07.691, 15519797.
29. Scorsetti M, Mancosu P, Navarria P, et al. Stereotactic body radiation therapy (SBRT) for adrenal metastases : a feasibility study of advanced techniques with modulated photons and protons. Strahlenther Onkol 2011, 187:238-244. 10.1007/s00066-011-2207-9, 21437767.
30. Timmerman RD, Paulus R, Galvin J, Michalski J, Straube W, Bradley J, Fakiris A, Bezjak A, Videtic G, Choy H. Stereotactic Body Radiation Therapy for Medically Inoperable Early-stage Lung Cancer Patients: Analysis of RTOG 0236. IJROBP 2009, 75:S3.
31. Eppinga W, Lagerwaard F, Verbakel W, Slotman B, Senan S. Volumetric modulated arc therapy for advanced pancreatic cancer. Strahlenther Onkol 2010, 186:382-387. 10.1007/s00066-010-2094-5, 20582394.
32. Stieler F, Wolff D, Bauer L, Wertz HJ, Wenz F, Lohr F. Reirradiation of spinal column metastases: comparison of several treatment techniques and dosimetric validation for the use of VMAT. Strahlenther Onkol 2011, 187:406-415. 10.1007/s00066-011-2198-6, 21713397.
33. Wang X, Krishnan S, Zhang X, et al. Proton radiotherapy for liver tumors: dosimetric advantages over photon plans. Med Dosim 2008, 33:259-267. 10.1016/j.meddos.2007.04.008, 18973852.