Brain volume findings in 6-month-old infants at high familial risk for autism

American Journal of Psychiatry

Volumn 169, Issue 6, 2012, Pages 601-608

  Hazlett, Heather Cody ^a,b,c,d,e,f   Gu, Hongbin ^a,b,c,d,e,f   McKinstry, Robert C ^a,b,c,d,e,f   Shaw, Dennis W W ^a,b,c,d,e,f   Botteron, Kelly N ^a,b,c,d,e,f   Dager, Stephen R ^a,b,c,d,e,f   Styner, Martin ^a,b,c,d,e,f   Vachet, Clement ^a,b,c,d,e,f   Gerig, Guido ^a,b,c,d,e,f   Paterson, Sarah J ^a,b,c,d,e,f   Schultz, Robert T ^a,b,c,d,e,f   Estes, Annette M ^a,b,c,d,e,f   Evans, Alan C ^a,b,c,d,e,f   Piven, Joseph ^a,b,c,d,e,f  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTISM; BRAIN CORTEX; BRAIN SIZE; CEREBELLUM; CEREBROSPINAL FLUID; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; GENETIC RISK; HEAD CIRCUMFERENCE; HIGH RISK INFANT; HUMAN; HUMAN TISSUE; INFANT; LATERAL BRAIN VENTRICLE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 84862232508     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2012.11091425     Document Type: Article

References (36)

1. Piven J, Nehme E, Simon J, Barta P, Pearlson G, Folstein SE: Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle. Biol Psychiatry 1992; 31:491-504
2. Piven J, Arndt S, Bailey J, Andreasen N: Regional brain enlargement in autism: a magnetic resonance imaging study. J Am Acad Child Adolesc Psychiatry 1996; 35:530-536 (Pubitemid 126418617)
3. Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, Chisum HJ, Moses P, Pierce K, Lord C, Lincoln AJ, Pizzo S, Schreibman L, Haas RH, Akshoomoff NA, Courchesne RY: Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology 2001; 57:245-254 (Pubitemid 32667357)
4. Sparks BF, Friedman SD, Shaw DW, Aylward EH, Echelard D, Artru AA, Maravilla KR, Giedd JN, Munson J, Dawson G, Dager SR: Brain structural abnormalities in young children with autism spectrum disorder. Neurology 2002; 59:184-192 (Pubitemid 34779175)
5. Bailey A, Le Couteur A, Gottesman I, Bolton P, Simonoff E, Yuzda E, Rutter M: Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med 1995; 25:63-77
6. Lainhart JE, Piven J, Wzorek M, Landa R, Santegelo SL, Coon H, Folstein SE: Macrocephaly in children and adults with autism. J Am Acad Child Adolesc Psychiatry 1997; 36:282-289
7. Lainhart JE, Bigler ED, Bocian M, Coon H, Dinh E, Dawson G, Deutsch CK, Dunn M, Estes A, Tager-Flusberg H, Folstein S, Hepburn S, Hyman S, McMahon W, Minshew N, Munson J, Osann K, Ozonoff S, Rodier P, Rogers S, Sigman M, Spence MA, Stodgell CJ, Volkmar F: Head circumference and height in autism: a study by the Collaborative Program of Excellence in Autism. Am J Med Genet A 2006; 140:2257-2274 (Pubitemid 44684952)
8. Bailey A, Luthert P, Bolton P, LeCouteur A, Rutter M: Autism and megalencephaly. Lancet 1993; 34:1225-1226
9. Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, Piven J: Magnetic resonance imaging and head circumference study of brain size in autism. Arch Gen Psychiatry 2005; 62:1366-1376 (Pubitemid 41746614)
10. Hazlett HC, Poe MD, Gerig G, Styner M, Chappell C, Smith RG, Vachet C, Piven J: Early brain overgrowth in autism associated with an increase in cortical surface area before age 2 years. Arch Gen Psychiatry 2011; 68:467-476
11. Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akschoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E: Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci 2010; 30:4419-4427
12. Mosconi MW, Hazlett HC, Poe MD, Gerig G, Smith RG, Piven J: Longitudinal study of amygdala volume and joint attention in 2- to 4- year old children with autism. Arch Gen Psychiatry 2009; 66:509-516
13. Courchesne E, Campbell K, Solso S: Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Res 2011; 22:138-145
14. Constantino JN, Majmudar P, Bottini A, Arvin M, Virkud Y, Simons P, Spitznagel E: Infant head growth in male siblings of children with and without autism spectrum disorders. J Neurodev Disord 2010; 2:39-46
15. Zwaigenbaum L, Bryson S, Rogers T, Roberts W, Brain J, Szatmari P: Behavioral manifestations of autism in the first year of life. Int J Dev Neurosci 2005; 23:143-152 (Pubitemid 40313548)
16. Knickmeyer RC, Gouttard S, Kang C, Evans D, Wilber K, Smith JK, Hamer RM, Lin W, Gerig G, Gilmore JH: A structural MRI study of human brain development from birth to 2 years. J Neurosci 2008; 28:12176-12182
17. Ozonoff S, Young GS, Carter A, Messinger D, Yirmiya N, Zwaigenbaum L, Bryson S, Carver LJ, Constantino J, Dobkins K, Hutman T, Iverson JM, Landa R, Rogers SJ, Sigman M, Stone WL: Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics 2011; 128:e488-e495
18. Lord C, Rutter M, Le Couteur A: Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994; 24:659-685 (Pubitemid 24309810)
19. Mullen EM: Mullen Scales of Early Learning: AGS Edition. Circle Pines, Minn, AGS Publishing, 1995
20. Sparrow SS, Balla D, Cicchetti DV: Vineland Adaptive Behavior Scales, 2nd ed. Shoreview, Minn, American Guidance Service, 2005
21. Bryson SE, Zwaigenbaum L, McDermott C, Rombough V, Brian J: The Autism Observation Scale for Infants: scale development and reliability data. J Autism Dev Disord 2008; 38:731-738 (Pubitemid 351421887)
22. Fonov V, Janke A, Caramanos Z, Arnold D, Narayanan S, Pike GB, Collins DL: Improved precision in the measurement of longitudinal global and regional volumetric changes via a novel MRIgradient distortion characterization and correction technique, in Medical Imaging and Augmented Reality: Lecture Notes in Computer Science, vol 6326. Edited by Liao H, Edwards PJ, Pan X, Fan Y, Yang G-Z. New York, Springer, 2010, pp 324-333
23. Gouttard S, Styner M, Prastawa M, Gerig G: Assessment of reliability of multi-site neuroimaging via traveling phantom study. Med Image Comput Assist Interv 2008; 11(pt 2):263-270
24. Van Leemput K, Maes F, Vandermeulen D, Suetens P: Automated model-based tissue classification of MR images of the brain. IEEE Trans Med Imaging 1999; 18:897-908 (Pubitemid 32211105)
25. Gouttard S, Styner M, Joshi S, Smith RG, Hazlett HC, Gerig G: Subcortical structure segmentation using probabilistic atlas priors, in SPIE Medical Imaging 2007: Image Processing: Proceedings, vol 6512. Edited by Pluim JPW, Reinhardt JM. Bellingham, Wash, SPIE, 2007, p 88
26. Yushkevich PA, Piven J, Hazlett HC, Smith RG, Ho S, Gee JC, Gerig G: User-guided 3D active contour segmentation of anatomical structures: significantly improved efficacy and reliability. Neuroimage 2006; 31:1116-1128 (Pubitemid 43851334)
27. Yashiro K, Riday TT, Condon KH, Roberts AC, Bernardo DR, Prakash R, Weinberg RJ, Ehlers MD, Philpot BD: Ube3a is required for experience-dependent maturation of the neocortex. Nat Neurosci 2009; 12:777-783
28. Dolen G, Osterweil E, Rao BS, Smith GB, Auerbach BD, Chattarji S, Bear MF: Correction of fragile X syndrome in mice. Neuron 2007; 56:955-962 (Pubitemid 350251119)
29. Morrow EM, Yoo SY, Flavell SW, Kim TK, Lin Y, Hill RD, Mukaddes NM, Balkhy S, Glascon G, Hashmi A, Al-Saad S, Ware J, Joseph RM, Greenblatt R, Gleason D, Ertelt JA, Apse KA, Bodell A, Partlow JN, Barry B, Yao H, Markianos K, Ferland RJ, Greenberg ME, Walsh CA: Identifying autism loci and genes by tracing recent shared ancestry. Science 2008; 321:218-223 (Pubitemid 351989087)
30. Chenn A, Walsh CA: Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 2002; 297:365-369 (Pubitemid 34790759)
31. Wetherby AM, Brosnan-Maddox S, Peace V, Newton L: Validation of the Infant-Toddler Checklist as a broadband screener for autism spectrum disorders from 9 to 24 months of age. Autism 2008; 12:487-511
32. Zeegers M, Van Der Grond J, Durston S, Nievelstein RJ, Witkamp T, Van Daalen E, Buitelaar J, Engeland HV: Radiological findings in autistic and developmentally delayed children. Brain Dev 2006; 28:495-499 (Pubitemid 44051818)
33. Steiner CE, Guerreiro MM, Marques-de-Faria AP: Acrocallosal syndrome and autism. J Autism Dev Disord 2004; 34:723-726
34. Taber KH, Shaw JB, Loveland KA, Pearson DA, Lane DM, Hayman LA: Accentuated Virchow-Robin spaces in the centrum semiovale in children with autistic disorder. J Comput Assist Tomogr 2004; 28:263-268 (Pubitemid 38364993)
35. Boddaert N, Zilbovicius M, Philipe A, Robel L, Bourgeois M, Barthelemy C, Seidenwurm D, Meresse I, Laurieer L, Desguerre I, Bahi-Buisson N, Brunelle F, Munnich A, Samson Y, Mouren M-C, Chabane N: MRI findings in 77 children with non-syndromic autistic disorder. PLoS One 2009; 4(2):e4415
36. Wolff JJ, Gu H, Gerig G, Elison JT, Styner M, Gouttard S, Botteron KN, Dager SR, Dawson G, Estes AM, Evans A, Hazlett HC, Kostopoulos P, McKinstry RC, Paterson SJ, Schultz RT, Zwaigenbaum L, Piven J: Differences in white matter fiber tract development present from 6 to 24 months in infants with autism. Am J Psychiatry 2012; 169:589-600