Generation of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5

Biochemical Journal

Volumn 444, Issue 3, 2012, Pages 611-617

  Braten, Ori ^a   Shabek, Nitzan ^a   Kravtsova Ivantsiv, Yelena ^a   Ciechanover, Aaron ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

26S proteasome; Degradation; Free ubiquitin chains; Homologous to E6 AP carboxy terminus ubiquitin ligase 5 (HUL5); Methyl methanesulfonate (MMS); Ubiquitin fusion degradation 4 (UFD4)

Indexed keywords

DNA; HECT UBIQUITIN LIGASE 5; UBIQUITIN; UBIQUITIN FUSION DEGRADATION 4; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN STABILITY; SACCHAROMYCES CEREVISIAE; STRESS; UPREGULATION; YEAST CELL;

CATALYSIS; HEK293 CELLS; HUMANS; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION;

EID: 84862217564     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111840     Document Type: Article

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