Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence

JACC: Cardiovascular Imaging

Volumn 5, Issue 6, 2012, Pages 607-615

  Hara, Tetsuya ^a   Bhayana, Brijesh ^a   Thompson, Brian ^a   Kessinger, Chase W ^a   Khatri, Ashok ^a   McCarthy, Jason R ^a   Weissleder, Ralph ^a   Lin, Charles P ^a   Tearney, Guillermo J ^a   Jaffer, Farouc A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

DVT; fibrin; fluorescence; molecular imaging; optical imaging

Indexed keywords

FIBRIN; FLUORESCENT DYE; FRESH FROZEN PLASMA; FTP11 CY7; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOFLUORESCENCE IMAGING; BINDING KINETICS; COMPUTER ASSISTED TOMOGRAPHY; CONJUGATION; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DRUG HALF LIFE; DRUG STRUCTURE; FEMORAL VEIN; FIBRIN DEPOSITION; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; HISTOPATHOLOGY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; JUGULAR VEIN; MOLECULAR IMAGING; MOUSE; NEAR INFRARED FLUORESCENCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN TARGETING; SENSITIVITY AND SPECIFICITY; SHAM PROCEDURE; SOLID PHASE SYNTHESIS;

ANIMALS; CHLORIDES; DISEASE MODELS, ANIMAL; FEMORAL VEIN; FERRIC COMPOUNDS; FIBRIN; FLUORESCENT DYES; HALF-LIFE; HUMANS; INDOLES; INJECTIONS, INTRAVENOUS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR IMAGING; OLIGOPEPTIDES; PHLEBOGRAPHY; SPECTROSCOPY, NEAR-INFRARED; TISSUE DISTRIBUTION; TOMOGRAPHY, X-RAY COMPUTED; VENOUS THROMBOSIS;

EID: 84862198341     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2012.01.017     Document Type: Article

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