Association of Parkinson's disease with six single nucleotide polymorphisms located in four PARK genes in the northern Han Chinese population

Journal of Clinical Neuroscience

Volumn 19, Issue 7, 2012, Pages 1011-1015

  Zhou, Yishu ^a   Luo, Xiaoguang ^a   Li, Fengrui ^a,b   Tian, Xiaofei ^a   Zhu, Lanhui ^a   Yang, Yichun ^c   Ren, Yan ^a   Pang, Hao ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b BAOTOU MEDICAL COLLEGE   (China)

^c DALIAN UNIVERSITY   (China)

Author keywords

Mismatched multiplex amplification; PARK genes; Parkinson's disease; PCR RFLP; Polymorphism

Indexed keywords

ADULT; AGED; ARTICLE; CHINESE; CONTROLLED STUDY; DENATURATION; FEMALE; GENE; GENE AMPLIFICATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HIGH THROUGHPUT SEQUENCING; HUMAN; MAJOR CLINICAL STUDY; MALE; PARK GENE; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-SERINE-THREONINE KINASES; YOUNG ADULT;

EID: 84862198228     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2011.09.028     Document Type: Article

References (28)

1. H.R. Martinez, H. Gonzalez-Gonzalez, and L. Cantu-Martinez PARKIN-coding polymorphisms are not associated with Parkinson's disease in a population from northeastern Mexico Neurosci Lett 468 2010 264 266
2. E. Deas, H. Plun-Favreau, and N.W. Wood PINK1 function in health and disease EMBO Mol Med 1 2009 152 165
3. A. Di Fonzo, C.F. Rohe, and J. Ferreira A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease Lancet 365 2005 412 415 (Pubitemid 40179228)
4. E.K. Tan, P. Ho, and L. Tan PLA2G6 mutations and Parkinson's disease Ann Neurol 67 2010 148
5. S. Papapetropoulos, N. Adi, and L. Shehadeh Is the G2019S LRRK2 mutation common in all southern European populations? J Clin Neurosci 15 2008 1027 1030
6. V. Bonifati, C.F. Rohe, and G.J. Breedveld Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes Neurology 65 2005 87 95 (Pubitemid 40967781)
7. R. Kumazawa, H. Tomiyama, and Y. Li Mutation analysis of the PINK1 gene in 391 patients with Parkinson disease Arch Neurol 65 2008 802 808 (Pubitemid 351831459)
8. K. Nuytemans, J. Theuns, and M. Cruts Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update Hum Mutat 31 2010 763 780
9. H. Tomiyama, Y. Li, and M. Funayama Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries Mov Disord 21 2006 1102 1108 (Pubitemid 44336593)
10. H. Pang, Y. Ding, and Y. Li Mismatched multiplex PCR amplification and subsequent RFLP analysis to simultaneously identify polymorphisms of erythrocytic ESD, GLO1, and GPT genes J Forensic Sci 56 Suppl. 1 2011 S176 S178
11. S. Purcell, B. Neale, and K. Todd-Brown PLINK: a tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575 (Pubitemid 47330214)
12. J.M. Choi, M.S. Woo, and H.I. Ma Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease Neurogenetics 9 2008 263 269
13. W.C. Nichols, N. Pankratz, and D. Hernandez Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease Lancet 365 2005 410 412 (Pubitemid 40179227)
14. X.K. An, R. Peng, and T. Li LRRK2 Gly2385Arg variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China Eur J Neurol 15 2008 301 305 (Pubitemid 351257927)
15. A. Di Fonzo, Y.H. Wu-Chou, and C.S. Lu A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan Neurogenetics 7 2006 133 138 (Pubitemid 44078290)
16. M.J. Farrer, J.T. Stone, and C.H. Lin Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia Parkinsonism Relat Disord 13 2007 89 92 (Pubitemid 46329522)
17. M. Funayama, Y. Li, and H. Tomiyama Leucine-rich repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population Neuroreport 18 2007 273 275
18. O.A. Ross, Y.R. Wu, and M.C. Lee Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease Ann Neurol 64 2008 88 92
19. E.K. Tan, R. Peng, and Y.R. Wu LRRK2 G2385R modulates age at onset in Parkinson's disease: A multi-center pooled analysis Am J Med Genet B Neuropsychiatr Genet 150B 2009 1022 1023
20. E.K. Tan, and L.M. Skipper Pathogenic mutations in Parkinson disease Hum Mutat 28 2007 641 653 (Pubitemid 47047290)
21. E.K. Tan, L.C. Tan, and H.Q. Lim LRRK2 R1628P increases risk of Parkinson's disease: replication evidence Hum Genet 124 2008 287 288
22. E.K. Tan, M. Tang, and L.C. Tan Lrrk2 R1628P in non-Chinese Asian races Ann Neurol 64 2008 472 473
23. J.M. Kim, J.Y. Lee, and H.J. Kim The LRRK2 G2385R variant is a risk factor for sporadic Parkinson's disease in the Korean population Parkinsonism Relat Disord 16 2010 85 88
24. C.P. Zabetian, M. Yamamoto, and A.N. Lopez LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease Mov Disord 24 2009 1034 1041
25. C.S. Lu, Y.H. Wu-Chou, and M. van Doeselaar The LRRK2 Arg1628Pro variant is a risk factor for Parkinson's disease in the Chinese population Neurogenetics 9 2008 271 276
26. L. Yu, F. Hu, and X. Zou LRRK2 R1628P contributes to Parkinson's disease susceptibility in Chinese Han populations from mainland China Brain Res 1296 2009 113 116
27. Z. Zhang, J.M. Burgunder, and X. An LRRK2 R1628P variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China Mov Disord 24 2009 1902 1905
28. G.T. Sutherland, G.M. Halliday, and P.A. Silburn Do polymorphisms in the familial Parkinsonism genes contribute to risk for sporadic Parkinson's disease? Mov Disord 24 2009 833 838