LRRK2 G2385R modulates age at onset in Parkinson's disease: A multi-center pooled analysis

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 150, Issue 7, 2009, Pages 1022-1023

  Tan, E K ^a,b   Peng, R ^c   Wu, Y R ^d   Wu, R M ^e   Wu Chou, Y H ^d   Tan, L C ^a   An, X K ^c   Chen, C M ^d   Fook Chong, S ^a   Lu, C S ^d,f  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c SICHUAN UNIVERSITY   (China)

^d CHANG GUNG UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f NONE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; LEUCINE RICH REPEAT KINASE 2;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; EPIGENETICS; FEMALE; GENDER; GENE MUTATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HETEROZYGOSITY; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; RISK;

EID: 70349329841     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30923     Document Type: Letter

References (8)

1. An XK, Peng R, Li T, et al. 2008. LRRK2 Gly2385 Arg variant is a risk factor of Parkinson's disease among Han Chinese from mainland China. Eur J Neurol 15(3):301-305.
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3. Farrer MJ, Stone JT, Lin CH, et al. 2007. Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia. Parkinsonism Relat Disord 13(2):89-92.
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7. Tan EK, Skipper LM. 2007. Pathogenic mutations in Parkinson disease. Hum Mutat 28(7):641-653.
8. Tan EK, Zhao Y, Skipper L, et al. 2007. The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: Genetic and functional evidence. Hum Genet 120(6):857-863. (Pubitemid 46128841)