Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus

Pharmacological Reports

Volumn 64, Issue 2, 2012, Pages 256-265

  Tokarski, Krzysztof ^a   Zelek Molik, Agnieszka ^a   Duszyńska, Beata ^a   Satała, Grzegorz ^a   Bobula, Bartosz ^a   Kusek, Magdalena ^a   Chmielarz, Piotr ^a   Nalepa, Irena ^a   Hess, Grzegorz ^a,b  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

5 Carboxamidotryptamine; Adaptive changes; Epileptiform activity; Hippocampal slice; Imipramine; SB 269970

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; 5 CARBAMOYLTRYPTAMINE; IMIPRAMINE; MESSENGER RNA; SEROTONIN 7 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MALE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RECEPTOR AFFINITY; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 84862182754     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(12)70763-6     Document Type: Article

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