Peak and time-integrated shear rates independently predict flow-mediated dilation

Journal of Clinical Ultrasound

Volumn 40, Issue 6, 2012, Pages 341-351

  Stoner, Lee ^a,b   Mccully, Kevin K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

Blood flow; Endothelial function; FMD; Hierarchical linear modeling; Shear stress

Indexed keywords

ADULT; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRACHIAL ARTERY; ECHOGRAPHY; HAND STRENGTH; HUMAN; HYPEREMIA; ISCHEMIA; MALE; MECHANICAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCIBILITY; STATISTICAL MODEL; VASODILATATION;

ADULT; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRACHIAL ARTERY; HAND STRENGTH; HUMANS; HYPEREMIA; ISCHEMIA; LINEAR MODELS; MALE; REPRODUCIBILITY OF RESULTS; STRESS, MECHANICAL; VASODILATION;

EID: 84862180894     PISSN: 00912751     EISSN: 10970096     Source Type: Journal    
DOI: 10.1002/jcu.21900     Document Type: Article

References (54)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801.
2. Celermajer DS, Sorensen KE, Gooch VM, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111.
3. Corretti MC, Anderson TJ, Benjamin EJ, et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. J Am Coll Cardiol 2002; 39: 257.
4. Yoshida T, Kawano H, Miyamoto S, et al. Prognostic value of flow-mediated dilation of the brachial artery in patients with cardiovascular disease. Intern Med 2006; 45: 575.
5. Grewal J, Chan S, Frohlich J, et al. Assessment of novel risk factors in patients at low risk for cardiovascular events based on Framingham risk stratification. Clin Invest Med 2003; 26: 158.
6. Schroeder S, Enderle MD, Ossen R, et al. Noninvasive determination of endothelium-mediated vasodilation as a screening test for coronary artery disease: pilot study to assess the predictive value in comparison with angina pectoris, exercise electrocardiography, and myocardial perfusion imaging. Am Heart J 1999; 138: 731.
7. Green DJ, Jones H, Thijssen D, et al. Flow-mediated dilation and cardiovascular event prediction: Does nitric oxide matter? Hypertension 2011; 57: 363.
8. Joannides R, el Bakkali H, Richard V, et al. Evaluation of the determinants of flow-mediated radial artery vasodilatation in humans. Clin Exp Hypertens 1997; 19: 813.
9. Leeson P, Thorne S, Donald A, et al. Non-invasive measurement of endothelial function: effect on brachial artery dilatation of graded endothelial dependent and independent stimuli. Heart 1997; 78: 22.
10. Stoner L, Sabatier M, Edge K, et al. The relationship between blood velocity and conduit artery diameter, and the effects of smoking on vascular responsiveness. J Appl Physiol 2004; 96: 2139.
11. Stoner L, Sabatier MJ, Black CD, et al. Occasional cigarette smoking chronically affects arterial function. Ultrasound Med Biol 2008; 34: 1885.
12. Pyke KE, Jazuli F. Impact of repeated increases in shear stress via reactive hyperemia and handgrip exercise: no evidence of systematic changes in brachial artery FMD. Am J Physiol Heart Circ Physiol 2011; 300: H1078.
13. Pyke KE, Dwyer EM, Tschakovsky ME. Impact of controlling shear rate on flow-mediated dilation responses in the brachial artery of humans. J Appl Physiol 2004; 97: 499.
14. Harris RA, Padilla J, Rink LD, et al. Variability of flow-mediated dilation measurements with repetitive reactive hyperemia. Vasc Med 2006; 11: 1.
15. Kellogg DLJr, Liu Y, Kosiba IF, et al. Role of nitric oxide in the vascular effects of local warming of the skin in humans. J Appl Physiol 1999; 86: 1185.
16. Taylor WF, Johnson JM, O'Leary D, et al. Effect of high local temperature on reflex cutaneous vasodilation. J Appl Physiol 1984; 57: 191.
17. Hangiandreou NJ, James EM, McBane RD, et al. The effects of irreversible JPEG compression on an automated algorithm for measuring carotid artery intima-media thickness from ultrasound images. J Digit Imaging 2002; 15: 258.
18. Sabatier MJ, Stoner L, Reifenberger M, et al. Doppler ultrasound assessment of posterior tibial artery size in humans. J Clin Ultrasound 2006; 34: 223.
19. Stoner L, Sabatier M, VanHiel L, et al. Upper versus lower extremity arterial function after spinal cord injury. J Spinal Cord Med 2006; 29: 138.
20. Kizhakekuttu TJ, Gutterman DD, Phillips SA, et al. Measuring FMD in the brachial artery: How important is QRS gating? J Appl Physiol 2010; 109: 959.
21. Olive JL, Slade JM, Dudley GA, et al. Blood flow and muscle fatigue in SCI individuals during electrical stimulation. J Appl Physiol 2003; 94: 701.
22. Silke B, McAuley D. Accuracy and precision of blood pressure determination with the Finapres: an overview using re-sampling statistics. J Hum Hypertens 1998; 12: 403.
23. Raudenbush SW, Bryk AS. Hierarchical linear models: applications and data analysis methods (advanced quantitative techniques in the social sciences). Thousand Oaks, CA: SAGE Publications; 2001.
24. Pyke KE, Tschakovsky ME. Peak vs. total reactive hypereamia: Which determines the magnitude of flow-mediated dilation? J Appl Physiol 2007; 102: 1510.
25. Mullen MJ, Kharbanda RK, Cross J, et al. Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res 2001; 88: 145.
26. Lie M, Sejersted OM, Kiil F. Local regulation of vascular cross section during changes in femoral arterial blood flow in dogs. Circ Res 1970; 27: 727.
27. Hilton SM. A peripheral arterial conducting mechanism underlying dilatation of the femoral artery and concerned in functional vasodilatation in skeletal muscle. J Physiol 1959; 149: 93.
28. Koller A, Sun D, Huang A, et al. Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles. Am J Physiol 1994; 267: H326.
29. Koller A, Sun D, Kaley G. Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro. Circ Res 1993; 72: 1276.
30. Busse R, Edwards G, Feletou M, et al. EDHF: Bringing the concepts together. Trends Pharmacol Sci 2002; 23: 374.
31. Martin CM, Beltran-Del-Rio A, Albrecht A, et al. Local cholinergic mechanisms mediate nitric oxide-dependent flow-induced vasorelaxation in vitro. Am J Physiol 1996; 270: H442.
32. Frangos JA, Eskin SG, McIntire LV, et al. Flow effects on prostacyclin production by cultured human endothelial cells. Science 1985; 227: 1477.
33. Kuchan MJ, Jo H, Frangos JA. Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells. Am J Physiol 1994; 267: C753.
34. Frangos JA, Huang TY, Clark CB. Steady shear and step changes in shear stimulate endothelium via independent mechanisms-superposition of transient and sustained nitric oxide production. Biochem Biophys Res Commun 1996; 224: 660.
35. Macarthur H, Hecker M, Busse R, et al. Selective inhibition of agonist-induced but not shear stress-dependent release of endothelial autacoids by thapsigargin. Br J Pharmacol 1993; 108: 100.
36. Padilla J, Johnson BD, Newcomer SC, et al. Normalization of flow-mediated dilation to shear stress area under the curve eliminates the impact of variable hyperemic stimulus. Cardiovasc Ultrasound 2008; 6: 44.
37. Parker BA, Ridout SJ, Proctor DN. Age and flow-mediated dilation: a comparison of dilatory responsiveness in the brachial and popliteal arteries. Am J Physiol Heart Circ Physiol 2006; 291: H3043.
38. Atkinson G, Batterham AM, Black MA, et al. Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function? J Appl Physiol 2009; 107: 1893.
39. Thijssen DH, Bullens LM, van Bemmel MM, et al. Does arterial shear explain the magnitude of flow-mediated dilation?: A comparison between young and older humans. Am J Physiol Heart Circ Physiol 2009; 296: H57.
40. De Groot PC, Poelkens F, Kooijman M, et al. Preserved flow mediated dilation in the inactive legs of spinal cord-injured individuals. Am J Physiol Heart Circ Physiol 2004; 287: H374.
41. Allison DB, Paultre F, Goran MI, et al. Statistical considerations regarding the use of ratios to adjust data. Int J Obes Relat Metab Disord 1995; 19: 644.
42. Stoner L, Sabatier MJ, Mahoney ET, et al. Electrical stimulation-evoked resistance exercise therapy improves arterial health after chronic spinal cord injury. Spinal Cord 2007; 45: 49.
43. Gnasso A, Carallo C, Irace C, et al. Association between intima-media thickness and wall shear stress in common carotid arteries in healthy male subjects. Circulation 1996; 94: 3257.
44. Betik AC, Luckham VB, Hughson RL. Flow-mediated dilation in human brachial artery after different circulatory occlusion conditions. Am J Physiol Heart Circ Physiol 2004; 286: H442.
45. Salazar Vazquez BY, Martini J, Chavez Negrete A, et al. Cardiovascular benefits in moderate increases of blood and plasma viscosity surpass those associated with lowering viscosity: Experimental and clinical evidence. Clin Hemorheol Microcirc 2010; 44: 75.
46. Black CD, Vickerson B, McCully KK. Noninvasive assessment of vascular function in the posterior tibial artery of healthy humans. Dyn Med 2003; 2: 1.
47. Naylor LH, Weisbrod CJ, O'Driscoll G, et al. Measuring peripheral resistance and conduit arterial structure in humans using Doppler ultrasound. J Appl Physiol 2005; 98: 2311.
48. Olive JL, McCully KK, Dudley GA. Blood flow response in individuals with incomplete spinal cord injuries. Spinal Cord 2002; 40: 640.
49. Napoli C, de Nigris F, Williams-Ignarro S, et al. Nitric oxide and atherosclerosis: an update. Nitric Oxide 2006; 15: 265.
50. Fetalvero KM, Martin KA, Hwa J. Cardioprotective prostacyclin signaling in vascular smooth muscle. Prostaglandins Other Lipid Mediat 2007; 82: 109.
51. Flavahan NA. Balancing prostanoid activity in the human vascular system. Trends Pharmacol Sci 2007; 28: 106.
52. Inaba Y, Chen JA, Bergmann SR. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging 2010; 26: 631.
53. Doshi SN, Naka KK, Payne N, et al. Flow-mediated dilatation following wrist and upper arm occlusion in humans: the contribution of nitric oxide. Clin Sci (Lond) 2001; 101: 629.
54. Stoner L, McCully KK. Velocity acceleration as a determinant of flow-mediated dilation. Ultrasound Med Biol; in press.