Quantification of islet size and architecture

Islets

Volumn 4, Issue 2, 2012, Pages 167-172

  Kilimnik, German ^a   Jo, Junghyo ^b   Periwal, Vipul ^b   Zielinski, Mark C ^a   Hara, Manami ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Diabetes; Islet; Islet architecture; Islet size; Pancreas

Indexed keywords

ARTICLE; CELL NUCLEUS; ENDOCRINE CELL; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET DELTA CELL;

ANIMALS; FEMALE; GLUCAGON-SECRETING CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INSULIN-SECRETING CELLS; MICE; MICROSCOPY, FLUORESCENCE; PANCREAS; VIDEO RECORDING;

EID: 84862171415     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.19256     Document Type: Article

References (10)

1. Kilimnik G, Zhao B, Jo J, Periwal V, Witkowski P, Misawa R, et al. Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes. PLoS One 2011; 6:27445; PMID:22102895; http://dx.doi.org/10.1371/journal.pone.0027445.
2. Kilimnik G, Kim A, Jo J, Miller K, Hara M. Quantification of pancreatic islet distribution in situ in mice. Am J Physiol Endocrinol Metab 2009; 297:1331-8; PMID:19808908; http://dx.doi.org/10.1152/ajpendo.00479.2009.
3. Miller K, Kim A, Kilimnik G, Jo J, Moka U, Periwal V, et al. Islet formation during the neonatal development in mice. PLoS One 2009; 4:7739; PMID:19893748; http://dx.doi.org/10.1371/journal.pone.0007739.
4. Kim A, Kilimnik G, Hara M. In situ quantification of pancreatic beta-cell mass in mice. J Vis Exp 2010; 40:1970; http://dx.doi.org/10.3791/1970.
5. Kim A, Kilimnik G, Guo C, Sung J, Jo J, et al. Computer-assisted large-scale visualization and quantification of pancreatic islet mass, size distribution and architecture. J Vis Exp 2011; 49:2471; http://dx.doi.org/10. 3791/2471.
6. Jo J, Kilimnik G, Kim A, Guo C, Periwal V, Hara M. Formation of pancreatic islets involves coordinated expansion of small islets and fission of large interconnected islet-like structures. Biophys J 2011; 101:565-74; PMID:21806924; http://dx.doi.org/10.1016/j.bpj.2011.06.042.
7. Hara M, Wang X, Kawamura T, Bindokas VP, Dizon RF, Alcoser SY, et al. Transgenic mice with green fluorescent protein-labeled pancreatic β-cells. Am J Physiol Endocrinol Metab 2003; 284:177-83; PMID:12388130.
8. Kharouta M, Miller K, Kim A, Wojcik P, Kilimnik G, Dey A, et al. No mantle formation in rodent islets - the prototype of islet revisited. Diabetes Res Clin Pract 2009; 85:252-7; PMID:19595468; http://dx.doi.org/10.1016/j. diabres.2009.06.021.
9. Kim A, Miller K, Jo J, Kilimnik G, Wojcik P, Hara M. Islet architecture: A comparative study. Islets 2009; 1:129-36; PMID:20606719; http://dx.doi.org/10. 4161/isl.1.2.9480.
10. Steiner DJ, Kim A, Miller K, Hara M. Pancreatic islet plasticity: interspecies comparison of islet architecture and composition. Islets 2010; 2:135-45; PMID:20657742; http://dx.doi.org/10.4161/isl.2.3.11815.