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Volumn 37, Issue 7, 2012, Pages 567-574

In vivo, in vitro toxicity and in vitro angiogenic inhibition of sunitinib malate

Author keywords

Angiogenesis; Choroidal neovascularization; Drug toxicity; Intravitreal injection; Tyrosine kinase inhibitor

Indexed keywords

PROTEIN TYROSINE KINASE INHIBITOR; SUNITINIB;

EID: 84862170803     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2011.635916     Document Type: Article
Times cited : (19)

References (33)
  • 2
    • 0342632445 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials - TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials - TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol. 1999;117:1329-1345.
    • (1999) Arch Ophthalmol. , vol.117 , pp. 1329-1345
  • 3
    • 39049179584 scopus 로고    scopus 로고
    • Age related macular degeneration
    • Arnold J. Age related macular degeneration. Clin Evid. 2006;15:877-888.
    • (2006) Clin Evid , vol.15 , pp. 877-888
    • Arnold, J.1
  • 4
    • 30944437438 scopus 로고    scopus 로고
    • Smoking and age-related macular degeneration: A review of association
    • DOI 10.1038/sj.eye.6701978, PII 6701978
    • Thornton J, Edwards R, Mitchell P, Harrison RA, Buchan I, Kelly SP. Smoking and age-related macular degeneration: A review of association. Eye (Lond). 2005;19:935-944. (Pubitemid 43114972)
    • (2005) Eye , vol.19 , Issue.9 , pp. 935-944
    • Thornton, J.1    Edwards, R.2    Mitchell, P.3    Harrison, R.A.4    Buchan, I.5    Kelly, S.P.6
  • 5
    • 33750305221 scopus 로고    scopus 로고
    • Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twenty-four-week results of an uncontrolled open-label clinical study
    • Moshfeghi AA, Rosenfeld PJ, Puliafito CA et al. Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twenty-four-week results of an uncontrolled open-label clinical study. Ophthalmology. 2006;113:2002.e1-2002.12.
    • (2006) Ophthalmology , vol.113
    • Moshfeghi, A.A.1    Rosenfeld, P.J.2    Puliafito, C.A.3
  • 6
    • 33846586501 scopus 로고    scopus 로고
    • Subgroup Analysis of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration
    • DOI 10.1016/j.ophtha.2006.10.045, PII S0161642006014849
    • Boyer DS, Antoszyk AN, Awh CC, Bhisitkul RB, Shapiro H, Acharya NR; MARINA Study Group. Subgroup analysis of the MARINA study of ranibizumab in neovascular age-related macular degeneration. Ophthalmology. 2007;114: 246-252. (Pubitemid 46172497)
    • (2007) Ophthalmology , vol.114 , Issue.2 , pp. 246-252
    • Boyer, D.S.1    Antoszyk, A.N.2    Awh, C.C.3    Bhisitkul, R.B.4    Shapiro, H.5    Acharya, N.R.6
  • 7
    • 58949093226 scopus 로고    scopus 로고
    • Primary intravitreal bevacizumab for subfoveal choroidal neovascularization in agerelated macular degeneration: Results of the Pan-American Collaborative Retina Study Group at 12 months follow-up
    • Pan-American Collaborative Retina Study Group
    • Arevalo JF, Fromow-Guerra J, Sanchez JG et al.; Pan-American Collaborative Retina Study Group. Primary intravitreal bevacizumab for subfoveal choroidal neovascularization in agerelated macular degeneration: Results of the Pan-American Collaborative Retina Study Group at 12 months follow-up. Retina (Philadelphia, Pa). 2008;28:1387-1394.
    • (2008) Retina (Philadelphia, Pa) , vol.28 , pp. 1387-1394
    • Arevalo, J.F.1    Fromow-Guerra, J.2    Sanchez, J.G.3
  • 8
    • 33748982649 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy
    • Avery RL, Pearlman J, Pieramici DJ et al. Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology. 2006;113:1695.e1-1695.15.
    • (2006) Ophthalmology , vol.113
    • Avery, R.L.1    Pearlman, J.2    Pieramici, D.J.3
  • 9
    • 57949094834 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study
    • ANCHOR Study Group
    • Brown DM, Michels M, Kaiser PK, Heier JS, Sy JP, Ianchulev T; ANCHOR Study Group. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology. 2009;116:57-65.e5.
    • (2009) Ophthalmology , vol.116
    • Brown, D.M.1    Michels, M.2    Kaiser, P.K.3    Heier, J.S.4    Sy, J.P.5    Ianchulev, T.6
  • 10
    • 46949111802 scopus 로고    scopus 로고
    • Ranibizumab and pegaptanib for the treatment of age-related macular degeneration: A systematic review and economic evaluation
    • Colquitt JL, Jones J, Tan SC, Takeda A, Clegg AJ, Price A. Ranibizumab and pegaptanib for the treatment of age-related macular degeneration: A systematic review and economic evaluation. Health Technol Assess. 2008;12:iii-iv, ix.
    • (2008) Health Technol Assess , vol.12
    • Colquitt, J.L.1    Jones, J.2    Tan, S.C.3    Takeda, A.4    Clegg, A.J.5    Price, A.6
  • 11
    • 67149101784 scopus 로고    scopus 로고
    • A variable-dosing regimen with intravitreal ranibizumab for neovascular agerelated macular degeneration: Year 2 of the PrONTO Study
    • Lalwani GA, Rosenfeld PJ, Fung AE et al. A variable-dosing regimen with intravitreal ranibizumab for neovascular agerelated macular degeneration: Year 2 of the PrONTO Study. Am J Ophthalmol. 2009;148:43-58.e1.
    • (2009) Am J Ophthalmol , vol.148
    • Lalwani, G.A.1    Rosenfeld, P.J.2    Fung, A.E.3
  • 12
    • 20144372969 scopus 로고    scopus 로고
    • Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twelve-week results of an uncontrolled open-label clinical study
    • DOI 10.1016/j.ophtha.2005.02.007, PII S0161642005002976
    • Michels S, Rosenfeld PJ, Puliafito CA, Marcus EN, Venkatraman AS. Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelveweek results of an uncontrolled open-label clinical study. Ophthalmology. 2005;112:1035-1047. (Pubitemid 40797459)
    • (2005) Ophthalmology , vol.112 , Issue.6 , pp. 1035-1047
    • Michels, S.1    Rosenfeld, P.J.2    Puliafito, C.A.3    Marcus, E.N.4    Venkatraman, A.S.5
  • 13
    • 42449094689 scopus 로고    scopus 로고
    • Comparison of two doses of intravitreal bevacizumab (avastin) for treatment of macular edema secondary to branch retinal vein occlusion: Results from the Pan-American collaborative retina study group at 6 months of follow-up
    • DOI 10.1097/IAE.0b013e3181619bee, PII 0000698220080200000003
    • Wu L, Arevalo JF, Roca JA et al.; Pan-American Collaborative Retina Study Group (PACORES). Comparison of two doses of intravitreal bevacizumab (Avastin) for treatment of macular edema secondary to branch retinal vein occlusion: Results from the Pan-American Collaborative Retina Study Group at 6 months of follow-up. Retina (Philadelphia, Pa). 2008;28:212-219. (Pubitemid 351643150)
    • (2008) Retina , vol.28 , Issue.2 , pp. 212-219
    • Wu, L.1    Arevalo, J.F.2    Roca, J.A.3    Maia, M.4    Berrocal, M.H.5    Rodriguez, F.J.6    Evans, T.7    Costa, R.A.8    Cardillo, J.9
  • 15
    • 34548527086 scopus 로고    scopus 로고
    • Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth
    • Paschoalin T, Carmona AK, Rodrigues EG et al. Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth. Mol Cancer. 2007;6:44.
    • (2007) Mol Cancer , vol.6 , pp. 44
    • Paschoalin, T.1    Carmona, A.K.2    Rodrigues, E.G.3
  • 16
    • 84862218731 scopus 로고    scopus 로고
    • ARVO Animals in Research Committee
    • ARVO. ARVO (ed.). USA: ARVO
    • ARVO. ARVO Animals in Research Committee. In: ARVO (ed.). ARVO Animals in Research Committee. USA: ARVO; 1996: pp. 1, 20.
    • (1996) ARVO Animals in Research Committee
  • 18
    • 59049100882 scopus 로고    scopus 로고
    • ISCEV Standard for full-field clinical electroretinography (2008 update)
    • International Society for Clinical Electrophysiology of Vision
    • Marmor MF, Fulton AB, Holder GE, Miyake Y, Brigell M, Bach M; International Society for Clinical Electrophysiology of Vision. ISCEV Standard for full-field clinical electroretinography (2008 update). Doc Ophthalmol. 2009;118:69-77.
    • (2009) Doc Ophthalmol , vol.118 , pp. 69-77
    • Marmor, M.F.1    Fulton, A.B.2    Holder, G.E.3    Miyake, Y.4    Brigell, M.5    Bach, M.6
  • 19
  • 20
    • 21344444322 scopus 로고    scopus 로고
    • The effects of indocyanine green and endoillumination on rabbit retina: An electroretinographic and histological study
    • DOI 10.1136/bjo.2004.061093
    • Kwok AK, Lai TY, Yeung CK, Yeung YS, Li WW, Chiang SW. The effects of indocyanine green and endoillumination on rabbit retina: An electroretinographic and histological study. Br J Ophthalmol. 2005;89:897-900. (Pubitemid 40904817)
    • (2005) British Journal of Ophthalmology , vol.89 , Issue.7 , pp. 897-900
    • Kwok, A.K.H.1    Lai, T.Y.Y.2    Yeung, C.-K.3    Yeung, Y.-S.4    Li, W.W.Y.5    Chiang, S.W.6
  • 21
    • 34248335859 scopus 로고    scopus 로고
    • Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes
    • DOI 10.1167/iovs.06-0828
    • Inan UU, Avci B, Kusbeci T, Kaderli B, Avci R, Temel SG. Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes. Invest Ophthalmol Vis Sci. 2007;48:1773-1781. (Pubitemid 351261365)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.4 , pp. 1773-1781
    • Inan, U.U.1    Avci, B.2    Kusbeci, T.3    Kaderli, B.4    Avci, R.5    Temel, S.G.6
  • 22
    • 66149105565 scopus 로고    scopus 로고
    • Preclinical investigation of the retinal biocompatibility of six novel vital dyes for chromovitrectomy
    • Rodrigues EB, Penha FM, Farah ME et al. Preclinical investigation of the retinal biocompatibility of six novel vital dyes for chromovitrectomy. Retina (Philadelphia, Pa). 2009;29:497-510.
    • (2009) Retina (Philadelphia, Pa) , vol.29 , pp. 497-510
    • Rodrigues, E.B.1    Penha, F.M.2    Farah, M.E.3
  • 24
    • 34247359005 scopus 로고    scopus 로고
    • Effects of subretinal injections of indocyanine green, trypan blue, and glucose in rabbit eyes
    • Penha FM, Maia M, Eid Farah M et al. Effects of subretinal injections of indocyanine green, trypan blue, and glucose in rabbit eyes. Ophthalmology. 2007;114:899-908.
    • (2007) Ophthalmology , vol.114 , pp. 899-908
    • Penha, F.M.1    Maia, M.2    Eid Farah, M.3
  • 26
    • 73549107407 scopus 로고    scopus 로고
    • Ability of new vital dyes to stain intraocular membranes and tissues in ocular surgery
    • Rodrigues EB, Penha FM, de Paula Fiod Costa E et al. Ability of new vital dyes to stain intraocular membranes and tissues in ocular surgery. Am J Ophthalmol. 2010;149:265-277.
    • (2010) Am J Ophthalmol , vol.149 , pp. 265-277
    • Rodrigues, E.B.1    Penha, F.M.2    De Paula Fiod Costa, E.3
  • 27
    • 77954619947 scopus 로고    scopus 로고
    • Molecular and clinical aspects of targeting the VEGF pathway in tumors
    • Korpanty G, Sullivan LA, Smyth E, Carney DN, Brekken RA. Molecular and clinical aspects of targeting the VEGF pathway in tumors. J Oncol. 2010;2010:652320.
    • (2010) J Oncol , vol.2010 , pp. 652320
    • Korpanty, G.1    Sullivan, L.A.2    Smyth, E.3    Carney, D.N.4    Brekken, R.A.5
  • 28
    • 84855515664 scopus 로고    scopus 로고
    • VEGF pathway inhibition by anticancer agent sunitinib and susceptibility to atherosclerosis plaque disruption
    • Ropert S, Vignaux O, Mir O, Goldwasser F. VEGF pathway inhibition by anticancer agent sunitinib and susceptibility to atherosclerosis plaque disruption. Invest New Drugs. 2011;29:1497-1499.
    • (2011) Invest New Drugs , vol.29 , pp. 1497-1499
    • Ropert, S.1    Vignaux, O.2    Mir, O.3    Goldwasser, F.4
  • 29
    • 77954856835 scopus 로고    scopus 로고
    • Benefits from pharmacological and pharmacokinetic properties of sunitinib for clinical development
    • Sablin MP, Dreyer C, Colichi C et al. Benefits from pharmacological and pharmacokinetic properties of sunitinib for clinical development. Expert Opin Drug Metab Toxicol. 2010;6:1005-1015.
    • (2010) Expert Opin Drug Metab Toxicol , vol.6 , pp. 1005-1015
    • Sablin, M.P.1    Dreyer, C.2    Colichi, C.3
  • 33
    • 0033847831 scopus 로고    scopus 로고
    • Quantitative relationship of the scotopic and photopic ERG to photoreceptor cell loss in light damaged rats
    • Sugawara T, Sieving PA, Bush RA. Quantitative relationship of the scotopic and photopic ERG to photoreceptor cell loss in light damaged rats. Exp Eye Res. 2000;70:693-705.
    • (2000) Exp Eye Res , vol.70 , pp. 693-705
    • Sugawara, T.1    Sieving, P.A.2    Bush, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.