-
1
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
R.S. Hotchkiss, and I.E. Karl The pathophysiology and treatment of sepsis N Engl J Med 348 2003 138 150
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
2
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
D.C. Angus, W.T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M.R. Pinsky Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care Crit Care Med 29 2001 1303 1310
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
3
-
-
79960227027
-
Hydroxyethyl starch (130 kD) inhibits toll-like receptor 4 signaling pathways in rat lungs challenged with lipopolysaccharide
-
J. Tian, Y. Wang, Z. He, Y. Gao, J.E. Rundhaug, and X. Wang Hydroxyethyl starch (130 kD) inhibits toll-like receptor 4 signaling pathways in rat lungs challenged with lipopolysaccharide Anesth Analg 113 2011 112 119
-
(2011)
Anesth Analg
, vol.113
, pp. 112-119
-
-
Tian, J.1
Wang, Y.2
He, Z.3
Gao, Y.4
Rundhaug, J.E.5
Wang, X.6
-
4
-
-
77957752777
-
The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila
-
M.S. Frutuoso, J.I. Hori, M.S. Pereira, D.S. Junior, F. Sonego, and K.S. Kobayashi The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila Microbes Infect 12 2010 819 827
-
(2010)
Microbes Infect
, vol.12
, pp. 819-827
-
-
Frutuoso, M.S.1
Hori, J.I.2
Pereira, M.S.3
Junior, D.S.4
Sonego, F.5
Kobayashi, K.S.6
-
5
-
-
38549084725
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
-
M. Hasegawa, Y. Fujimoto, P.C. Lucas, H. Nakano, K. Fukase, and G. Nunez A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation EMBO J 27 2008 373 383
-
(2008)
EMBO J
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
Fujimoto, Y.2
Lucas, P.C.3
Nakano, H.4
Fukase, K.5
Nunez, G.6
-
6
-
-
79955129532
-
Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
-
J.G. Magalhaes, J. Lee, K. Geddes, S. Rubino, D.J. Philpott, and S.E. Girardin Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands Eur J Immunol 41 2011 1445 1455
-
(2011)
Eur J Immunol
, vol.41
, pp. 1445-1455
-
-
Magalhaes, J.G.1
Lee, J.2
Geddes, K.3
Rubino, S.4
Philpott, D.J.5
Girardin, S.E.6
-
7
-
-
0036781052
-
NF-kappaB regulation in the immune system
-
Q. Li, and I.M. Verma NF-kappaB regulation in the immune system Nat Rev Immunol 2 2002 725 734
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
8
-
-
0034021896
-
Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis
-
F. Arnalich, E. Garcia-Palomero, J. Lopez, M. Jimenez, R. Madero, and J. Renart Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis Infect Immun 68 2000 1942 1945
-
(2000)
Infect Immun
, vol.68
, pp. 1942-1945
-
-
Arnalich, F.1
Garcia-Palomero, E.2
Lopez, J.3
Jimenez, M.4
Madero, R.5
Renart, J.6
-
9
-
-
34548175739
-
Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients
-
J. Brenmoehl, H. Herfarth, T. Gluck, F. Audebert, S. Barlage, and G. Schmitz Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients Intensive Care Med 33 2007 1541 1548
-
(2007)
Intensive Care Med
, vol.33
, pp. 1541-1548
-
-
Brenmoehl, J.1
Herfarth, H.2
Gluck, T.3
Audebert, F.4
Barlage, S.5
Schmitz, G.6
-
10
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo, and K. Kangawa Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 1999 656 660
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
11
-
-
1642354552
-
Ghrelin: Integrative neuroendocrine peptide in health and disease
-
J.T. Wu, and J.G. Kral Ghrelin: integrative neuroendocrine peptide in health and disease Ann Surg 239 2004 464 474
-
(2004)
Ann Surg
, vol.239
, pp. 464-474
-
-
Wu, J.T.1
Kral, J.G.2
-
12
-
-
4143111272
-
Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis
-
R. Wu, M. Zhou, X. Cui, H.H. Simms, and P. Wang Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis Am J Physiol Heart Circ Physiol 287 2004 H1296 H1302
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Wu, R.1
Zhou, M.2
Cui, X.3
Simms, H.H.4
Wang, P.5
-
13
-
-
37149045076
-
Ghrelin inhibits sympathetic nervous activity in sepsis
-
R. Wu, M. Zhou, P. Das, W. Dong, Y. Ji, and D. Yang Ghrelin inhibits sympathetic nervous activity in sepsis Am J Physiol Endocrinol Metab 293 2007 E1697 E1702
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Wu, R.1
Zhou, M.2
Das, P.3
Dong, W.4
Ji, Y.5
Yang, D.6
-
14
-
-
3242749843
-
Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells
-
V.D. Dixit, E.M. Schaffer, R.S. Pyle, G.D. Collins, S.K. Sakthivel, and R. Palaniappan Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells J Clin Invest 114 2004 57 66
-
(2004)
J Clin Invest
, vol.114
, pp. 57-66
-
-
Dixit, V.D.1
Schaffer, E.M.2
Pyle, R.S.3
Collins, G.D.4
Sakthivel, S.K.5
Palaniappan, R.6
-
15
-
-
34247640178
-
Ghrelin down-regulates proinflammatory cytokines in sepsis through activation of the vagus nerve
-
R. Wu, W. Dong, X. Cui, M. Zhou, H.H. Simms, and T.S. Ravikumar Ghrelin down-regulates proinflammatory cytokines in sepsis through activation of the vagus nerve Ann Surg 245 2007 480 486
-
(2007)
Ann Surg
, vol.245
, pp. 480-486
-
-
Wu, R.1
Dong, W.2
Cui, X.3
Zhou, M.4
Simms, H.H.5
Ravikumar, T.S.6
-
16
-
-
26444572289
-
Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1
-
R. Wu, W. Dong, M. Zhou, X. Cui, H. Hank Simms, and P. Wang Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1 Cardiovasc Res 68 2005 318 326
-
(2005)
Cardiovasc Res
, vol.68
, pp. 318-326
-
-
Wu, R.1
Dong, W.2
Zhou, M.3
Cui, X.4
Hank Simms, H.5
Wang, P.6
-
17
-
-
35348960888
-
Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats
-
R. Wu, W. Dong, M. Zhou, F. Zhang, C.P. Marini, and T.S. Ravikumar Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats Am J Respir Crit Care Med 176 2007 805 813
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 805-813
-
-
Wu, R.1
Dong, W.2
Zhou, M.3
Zhang, F.4
Marini, C.P.5
Ravikumar, T.S.6
-
19
-
-
0021742157
-
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models
-
J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models Gastroenterology 87 1984 1344 1350
-
(1984)
Gastroenterology
, vol.87
, pp. 1344-1350
-
-
Krawisz, J.E.1
Sharon, P.2
Stenson, W.F.3
-
20
-
-
34548022149
-
Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study
-
J.A. Kellum, L. Kong, M.P. Fink, L.A. Weissfeld, D.M. Yealy, and M.R. Pinsky Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study Arch Intern Med 167 2007 1655 1663
-
(2007)
Arch Intern Med
, vol.167
, pp. 1655-1663
-
-
Kellum, J.A.1
Kong, L.2
Fink, M.P.3
Weissfeld, L.A.4
Yealy, D.M.5
Pinsky, M.R.6
-
21
-
-
0033969341
-
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
-
C.A. Gogos, E. Drosou, H.P. Bassaris, and A. Skoutelis Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options J Infect Dis 181 2000 176 180
-
(2000)
J Infect Dis
, vol.181
, pp. 176-180
-
-
Gogos, C.A.1
Drosou, E.2
Bassaris, H.P.3
Skoutelis, A.4
-
23
-
-
33747649790
-
Pathophysiology of acute lung injury and the acute respiratory distress syndrome
-
L.B. Ware Pathophysiology of acute lung injury and the acute respiratory distress syndrome Semin Respir Crit Care Med 27 2006 337 349
-
(2006)
Semin Respir Crit Care Med
, vol.27
, pp. 337-349
-
-
Ware, L.B.1
-
24
-
-
0035891593
-
Cytokine balance in the lungs of patients with acute respiratory distress syndrome
-
W.Y. Park, R.B. Goodman, K.P. Steinberg, J.T. Ruzinski, F. Radella II, and D.R. Park Cytokine balance in the lungs of patients with acute respiratory distress syndrome Am J Respir Crit Care Med 164 2001 1896 1903
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1896-1903
-
-
Park, W.Y.1
Goodman, R.B.2
Steinberg, K.P.3
Ruzinski, J.T.4
Radella, I.I.F.5
Park, D.R.6
-
26
-
-
0038132126
-
Early alterations in neutrophil activation are associated with outcome in acute lung injury
-
K.Y. Yang, J.J. Arcaroli, and E. Abraham Early alterations in neutrophil activation are associated with outcome in acute lung injury Am J Respir Crit Care Med 167 2003 1567 1574
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1567-1574
-
-
Yang, K.Y.1
Arcaroli, J.J.2
Abraham, E.3
-
27
-
-
0036684681
-
Rip2: A novel therapeutic target for bacteria-induced inflammation?
-
S. Jeyaseelan Rip2: a novel therapeutic target for bacteria-induced inflammation? Trends Microbiol 10 2002 356
-
(2002)
Trends Microbiol
, vol.10
, pp. 356
-
-
Jeyaseelan, S.1
-
28
-
-
63649108380
-
The roles of TLRs, RLRs and NLRs in pathogen recognition
-
T. Kawai, and S. Akira The roles of TLRs, RLRs and NLRs in pathogen recognition Int Immunol 21 2009 317 337
-
(2009)
Int Immunol
, vol.21
, pp. 317-337
-
-
Kawai, T.1
Akira, S.2
-
29
-
-
34247177912
-
Role of Nods in bacterial infection
-
L.L. Bourhis, and C. Werts Role of Nods in bacterial infection Microbes Infect 9 2007 629 636
-
(2007)
Microbes Infect
, vol.9
, pp. 629-636
-
-
Bourhis, L.L.1
Werts, C.2
-
32
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
M.S. Hayden, and S. Ghosh Shared principles in NF-kappaB signaling Cell 132 2008 344 362
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
33
-
-
77957255771
-
Functional characterization of the NF-kappaB binding site in the human NOD2 promoter
-
C. Hu, L. Sun, Y. Hu, D. Lu, H. Wang, and S. Tang Functional characterization of the NF-kappaB binding site in the human NOD2 promoter Cell Mol Immunol 7 2010 288 295
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 288-295
-
-
Hu, C.1
Sun, L.2
Hu, Y.3
Lu, D.4
Wang, H.5
Tang, S.6
-
34
-
-
77954956543
-
Effects of hydroxyethyl starch (130 kD) on brain inflammatory response and outcome during normotensive sepsis
-
X. Feng, F. Zhang, R. Dong, H. Wang, J. Liu, and X. Liu Effects of hydroxyethyl starch (130 kD) on brain inflammatory response and outcome during normotensive sepsis Int Immunopharmacol 10 2010 859 864
-
(2010)
Int Immunopharmacol
, vol.10
, pp. 859-864
-
-
Feng, X.1
Zhang, F.2
Dong, R.3
Wang, H.4
Liu, J.5
Liu, X.6
-
35
-
-
33748919647
-
Influence of hydroxyethyl starch 130/0.4 in pulmonary neutrophil recruitment and acute lung injury during polymicrobial sepsis in rats
-
X. Feng, B. Ren, W. Xie, Z. Huang, J. Liu, and R. Guan Influence of hydroxyethyl starch 130/0.4 in pulmonary neutrophil recruitment and acute lung injury during polymicrobial sepsis in rats Acta Anaesthesiol Scand 50 2006 1081 1088
-
(2006)
Acta Anaesthesiol Scand
, vol.50
, pp. 1081-1088
-
-
Feng, X.1
Ren, B.2
Xie, W.3
Huang, Z.4
Liu, J.5
Guan, R.6
-
36
-
-
33747039219
-
Effects of hydroxyethyl starch 130/0.4 on pulmonary capillary leakage and cytokines production and NF-kappaB activation in CLP-induced sepsis in rats
-
X. Feng, W. Yan, X. Liu, M. Duan, X. Zhang, and J. Xu Effects of hydroxyethyl starch 130/0.4 on pulmonary capillary leakage and cytokines production and NF-kappaB activation in CLP-induced sepsis in rats J Surg Res 135 2006 129 136
-
(2006)
J Surg Res
, vol.135
, pp. 129-136
-
-
Feng, X.1
Yan, W.2
Liu, X.3
Duan, M.4
Zhang, X.5
Xu, J.6
-
37
-
-
33845344015
-
Protective roles of hydroxyethyl starch 130/0.4 in intestinal inflammatory response and survival in rats challenged with polymicrobial sepsis
-
X. Feng, J. Liu, M. Yu, S. Zhu, and J. Xu Protective roles of hydroxyethyl starch 130/0.4 in intestinal inflammatory response and survival in rats challenged with polymicrobial sepsis Clin Chim Acta 376 2007 60 67
-
(2007)
Clin Chim Acta
, vol.376
, pp. 60-67
-
-
Feng, X.1
Liu, J.2
Yu, M.3
Zhu, S.4
Xu, J.5
-
38
-
-
2442419837
-
Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells
-
W.G. Li, D. Gavrila, X. Liu, L. Wang, S. Gunnlaugsson, and L.L. Stoll Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells Circulation 109 2004 2221 2226
-
(2004)
Circulation
, vol.109
, pp. 2221-2226
-
-
Li, W.G.1
Gavrila, D.2
Liu, X.3
Wang, L.4
Gunnlaugsson, S.5
Stoll, L.L.6
-
39
-
-
50949098239
-
Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria
-
A. Chorny, P. Anderson, E. Gonzalez-Rey, and M. Delgado Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria J Immunol 180 2008 8369 8377
-
(2008)
J Immunol
, vol.180
, pp. 8369-8377
-
-
Chorny, A.1
Anderson, P.2
Gonzalez-Rey, E.3
Delgado, M.4
-
40
-
-
50849133889
-
Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection
-
T. Kodama, J. Ashitani, N. Matsumoto, K. Kangawa, and M. Nakazato Ghrelin treatment suppresses neutrophil-dominant inflammation in airways of patients with chronic respiratory infection Pulm Pharmacol Ther 21 2008 774 779
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 774-779
-
-
Kodama, T.1
Ashitani, J.2
Matsumoto, N.3
Kangawa, K.4
Nakazato, M.5
-
41
-
-
68249119722
-
Sepsis, ghrelin, the cholinergic anti-inflammatory pathway, gut mucosal hyperpermeability, and high-mobility group box 1
-
M.P. Fink Sepsis, ghrelin, the cholinergic anti-inflammatory pathway, gut mucosal hyperpermeability, and high-mobility group box 1 Crit Care Med 37 2009 2483 2485
-
(2009)
Crit Care Med
, vol.37
, pp. 2483-2485
-
-
Fink, M.P.1
-
42
-
-
84855216250
-
Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line
-
E.Z. Sung, N.F. Da Silva, S.J. Goodyear, P.G. McTernan, R.P. Arasaradnam, and C.U. Nwokolo Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line Mol Biol Rep 38 2011 4833 4838
-
(2011)
Mol Biol Rep
, vol.38
, pp. 4833-4838
-
-
Sung, E.Z.1
Da Silva, N.F.2
Goodyear, S.J.3
McTernan, P.G.4
Arasaradnam, R.P.5
Nwokolo, C.U.6
|