메뉴 건너뛰기




Volumn 129, Issue SUPPL. 1, 2012, Pages

PL-09 side effects of anti-angiogenic drugs

Author keywords

Anti angiogenic drugs; Cancer; Cancer treatment; Hemostasis; Thrombosis

Indexed keywords

ANGIOGENESIS INHIBITOR; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; PACLITAXEL; PLACEBO; SORAFENIB; SUNITINIB; WARFARIN; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

EID: 84862154963     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/S0049-3848(12)70016-6     Document Type: Conference Paper
Times cited : (111)

References (37)
  • 1
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • HP Gerber, N Ferrara Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies Cancer Res 165 3 2005 671 680 (Pubitemid 40216420)
    • (2005) Cancer Research , vol.65 , Issue.3 , pp. 671-680
    • Gerber, H.-P.1    Ferrara, N.2
  • 2
    • 79955567607 scopus 로고    scopus 로고
    • Noncardiac vascular toxicities of vascular endothelial growth factor inhibitors in advanced cancer: A review
    • D Keefe, J Bowen, R Gibson, T Tan, M Okera, A Stringer Noncardiac vascular toxicities of vascular endothelial growth factor inhibitors in advanced cancer: a review Oncologist 16 4 2011 432 444
    • (2011) Oncologist , vol.16 , Issue.4 , pp. 432-444
    • Keefe, D.1    Bowen, J.2    Gibson, R.3    Tan, T.4    Okera, M.5    Stringer, A.6
  • 3
    • 24944453855 scopus 로고    scopus 로고
    • Phase i trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: Pharmacokinetic and clinical results
    • HS Rugo, RS Herbst, G Liu, JW Park, MS Kies, HM Steinfeldt et al. Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results J Clin Oncol 23 24 2005 5474 5483
    • (2005) J Clin Oncol , vol.23 , Issue.24 , pp. 5474-5483
    • Rugo, H.S.1    Herbst, R.S.2    Liu, G.3    Park, J.W.4    Kies, M.S.5    Steinfeldt, H.M.6
  • 4
    • 79951865371 scopus 로고    scopus 로고
    • A phase 1 trial and pharmacokinetic study of cediranib, an orally bioavailable pan-vascular endothelial growth factor receptor inhibitor, in children and adolescents with refractory solid tumors
    • E Fox, R Aplenc, R Bagatell, MK Chuk, E Dombi, W Goodspeed et al. A phase 1 trial and pharmacokinetic study of cediranib, an orally bioavailable pan-vascular endothelial growth factor receptor inhibitor, in children and adolescents with refractory solid tumors J Clin Oncol 28 35 2010 5174 5181
    • (2010) J Clin Oncol , vol.28 , Issue.35 , pp. 5174-5181
    • Fox, E.1    Aplenc, R.2    Bagatell, R.3    Chuk, M.K.4    Dombi, E.5    Goodspeed, W.6
  • 5
    • 77953033291 scopus 로고    scopus 로고
    • Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis
    • BE Houk, CL Bello, B Poland, LS Rosen, GD Demetri, RJ Motzer Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis Cancer Chemother Pharmacol 66 2 2010 357 371
    • (2010) Cancer Chemother Pharmacol , vol.66 , Issue.2 , pp. 357-371
    • Houk, B.E.1    Bello, C.L.2    Poland, B.3    Rosen, L.S.4    Demetri, G.D.5    Motzer, R.J.6
  • 7
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • FF Kabbinavar, J Hambleton, RD Mass Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer J Clin Oncol 23 2005 3706 3712
    • (2005) J Clin Oncol , vol.23 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3
  • 12
    • 43049111427 scopus 로고    scopus 로고
    • Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: The implications of eastern cooperative oncology group 4599
    • DOI 10.3816/CLC.2008.n.015
    • RA Somer, E Sherman, CJ Langer Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: the implications of Eastern Cooperative Oncology Group 4599 Clin Lung Cancer 9 2 2008 102 105 (Pubitemid 351631921)
    • (2008) Clinical Lung Cancer , vol.9 , Issue.2 , pp. 102-105
    • Somer, R.A.1    Sherman, E.2    Langer, C.J.3
  • 13
    • 63049122188 scopus 로고    scopus 로고
    • Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab
    • AB Sandler, JH Schiller, R Gray, I Dimery, J Brahmer, M Samant et al. Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab J Clin Oncol 27 9 2009 1405 1412
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1405-1412
    • Sandler, A.B.1    Schiller, J.H.2    Gray, R.3    Dimery, I.4    Brahmer, J.5    Samant, M.6
  • 16
    • 33846440150 scopus 로고    scopus 로고
    • Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma
    • DOI 10.1634/theoncologist.12-1-107
    • EP Rock, V Goodman, JX Jiang, K Mahjoob, SL Verbois, D Morse et al. Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma Oncologist 12 1 2007 107 113 (Pubitemid 46143508)
    • (2007) Oncologist , vol.12 , Issue.1 , pp. 107-113
    • Rock, E.P.1    Goodman, V.2    Jiang, J.X.3    Mahjoob, K.4    Verbois, S.L.5    Morse, D.6    Dagher, R.7    Justice, R.8    Pazdur, R.9
  • 20
    • 70349393610 scopus 로고    scopus 로고
    • Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
    • Y Je, FA Schutz, TK Choueiri Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials Lancet Oncol 10 10 2009 967 974
    • (2009) Lancet Oncol , vol.10 , Issue.10 , pp. 967-974
    • Je, Y.1    Schutz, F.A.2    Choueiri, T.K.3
  • 21
    • 0142121282 scopus 로고    scopus 로고
    • Bevacizumab, bleeding, thrombosis, and warfarin
    • author reply, 3543.
    • S Kilickap, H Abali, I Celik Bevacizumab, bleeding, thrombosis, and warfarin J Clin Oncol 21 18 2003 3542 author reply, 3543.
    • (2003) J Clin Oncol , vol.21 , Issue.18 , pp. 3542
    • Kilickap, S.1    Abali, H.2    Celik, I.3
  • 22
    • 0344928503 scopus 로고    scopus 로고
    • Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors
    • DOI 10.1159/000073281
    • BC Kuenen Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors Pathophysiol Haemost Thromb 33 1 2003 13 14 (Pubitemid 37490520)
    • (2003) Pathophysiology of Haemostasis and Thrombosis , vol.33 , Issue.SUPPL. 1 , pp. 13-14
    • Kuenen, B.C.1
  • 23
    • 52049106205 scopus 로고    scopus 로고
    • The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway
    • JM Roodhart, MH Langenberg, E Witteveen, EE Voest The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway Curr Clin Pharmacol 3 2 2008 132 143
    • (2008) Curr Clin Pharmacol , vol.3 , Issue.2 , pp. 132-143
    • Roodhart, J.M.1    Langenberg, M.H.2    Witteveen, E.3    Voest, E.E.4
  • 24
    • 57749207937 scopus 로고    scopus 로고
    • Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice
    • T Meyer, L Robles-Carrillo, T Robson, F Langer, H Desai, M Davila et al. Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice J Thromb Haemost 7 1 2009 171 181
    • (2009) J Thromb Haemost , vol.7 , Issue.1 , pp. 171-181
    • Meyer, T.1    Robles-Carrillo, L.2    Robson, T.3    Langer, F.4    Desai, H.5    Davila, M.6
  • 27
    • 18744380623 scopus 로고    scopus 로고
    • Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation
    • abstract 3528.
    • J Hambleton, WF Novotny, H Hurwitz, L Fehrenbacher, T Cartwright, J Hainsworth et al. Bevacizumab does not increase bleeding in patients with metastatic colorectal cancer receiving concurrent anticoagulation J Clin Oncol 2 Suppl 2004 abstract 3528.
    • (2004) J Clin Oncol , vol.2 , Issue.SUPPL.
    • Hambleton, J.1    Novotny, W.F.2    Hurwitz, H.3    Fehrenbacher, L.4    Cartwright, T.5    Hainsworth, J.6
  • 28
    • 33645351051 scopus 로고    scopus 로고
    • Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC)
    • (abstract 3554).
    • J Hambleton, J Skillings, F Kabbinavar, E Bergsland, E Holmgren, SN Holden et al. Safety of low-dose aspirin (ASA) in a pooled analysis of 3 randomized, controlled trials (RCTs) of bevacizumab (BV) with chemotherapy (CT) in patients (pts) with metastatic colorectal cancer (mCRC) J Clin Oncol 23 suppl 2005 259s (abstract 3554).
    • (2005) J Clin Oncol , vol.23 , Issue.SUPPL.
    • Hambleton, J.1    Skillings, J.2    Kabbinavar, F.3    Bergsland, E.4    Holmgren, E.5    Holden, S.N.6
  • 29
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • F Kabbinavar, HI Hurwitz, L Fehrenbacher Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer J Clin Oncol 21 1 2003 60 65
    • (2003) J Clin Oncol , vol.21 , Issue.1 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 30
    • 33748752619 scopus 로고    scopus 로고
    • A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: Results from the eastern cooperative oncology group study E2200
    • DOI 10.1093/annonc/mdl161
    • BJ Giantonio, DE Levy, PJ O'dwyer, NJ Meropol, PJ Catalano, AB Benson 3rd, Eastern Cooperative Oncology Group A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200 Ann Oncol 17 9 2006 1399 1403 (Pubitemid 44400378)
    • (2006) Annals of Oncology , vol.17 , Issue.9 , pp. 1399-1403
    • Giantonio, B.J.1    Levy, D.E.2    O'Dwyer, P.J.3    Meropol, N.J.4    Catalano, P.J.5    Benson III, A.B.6
  • 31
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • DOI 10.1200/JCO.2006.09.6305
    • BJ Giantonio, PJ Catalano, NJ Meropol, PJ O'Dwyer, EP Mitchell, SR Alberts et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200 J Clin Oncol 25 12 2007 1539 1544 (Pubitemid 46733080)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.12 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 32
    • 49049105525 scopus 로고    scopus 로고
    • Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE Study
    • HS Hochster, LL Hart, RK Ramanathan, BH Childs, JD Hainsworth, AL Cohn et al. Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE Study J Clin Oncol 26 21 2008 3523 3529
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3523-3529
    • Hochster, H.S.1    Hart, L.L.2    Ramanathan, R.K.3    Childs, B.H.4    Hainsworth, J.D.5    Cohn, A.L.6
  • 33
    • 66149147757 scopus 로고    scopus 로고
    • Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
    • CJ Allegra, G Yothers, MJ O'Connell, S Sharif, LH Colangelo, SH Lopa et al. Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer J Clin Oncol 27 20 2009 3385 3390
    • (2009) J Clin Oncol , vol.27 , Issue.20 , pp. 3385-3390
    • Allegra, C.J.1    Yothers, G.2    O'Connell, M.J.3    Sharif, S.4    Colangelo, L.H.5    Lopa, S.H.6
  • 35
    • 34447130180 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin®) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
    • DOI 10.1634/theoncologist.12-6-713
    • MH Cohen, J Gootenberg, P Keegan, R Pazdur FDA drug approval summary: bevacizumab (Avastin) plus Carboplatin and Paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer Oncologist 12 6 2007 713 718 (Pubitemid 47036205)
    • (2007) Oncologist , vol.12 , Issue.6 , pp. 713-718
    • Cohen, M.H.1    Gootenberg, J.2    Keegan, P.3    Pazdur, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.