Electrical stimulation of cerebellar fastigial nucleus promotes the expression of growth arrest and DNA damage inducible gene β and motor function recovery in cerebral ischemia/reperfusion rats

Neuroscience Letters

Volumn 520, Issue 1, 2012, Pages 110-114

  Liu, Bin ^a   Li, Jianrui ^a   Li, Longling ^a   Yu, Lehua ^a   Li, Changqing ^a  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia; Fastigial nucleus electrical stimulation; Gadd45

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE BETA PROTEIN; MESSENGER RNA; NYLON; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ELECTROSTIMULATION; FASTIGIAL NUCLEUS; MALE; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ANIMALS; ANTIGENS, DIFFERENTIATION; BRAIN ISCHEMIA; CEREBELLAR NUCLEI; ELECTRIC STIMULATION THERAPY; MALE; MOTOR SKILLS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 84862123915     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.05.044     Document Type: Article

References (28)

1. Barreto G., Schäfer A., Marhold J., Stach D., Swaminathan S.K., Handa V., Döderlein G., Maltry N., Wu W., Lyko F., Niehrs C. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007, 445:671-675.
2. Belayev L., Alonso O.F., Busto R., Zhao W., Ginsberg M.D. Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 1996, 27:1616-1622.
3. Block F. Global ischemia and behavioural deficits. Progress in Neurobiology 1999, 58:279-295.
4. Chen J., Uchimura K., Stetler R.A., Zhu R.L., Nakayama M., Jin K., Graham S.H., Simon R.P. Transient global ischemia triggers expression of the DNA damage-inducible gene GADD45 in the rat brain. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1998, 18:646-657. (PubMed: 9626189).
5. Doba N., Reis D.J. Changes in regional blood flow and cardiodynamics evoked by electrical stimulation of the fastigial nucleus in the cat and their similarity to orthostatic reflexes. The Journal of Physiology 1972, 227:729-747.
6. Endres M., Meisel A., Biniszkiewicz D., Namura S., Prass K., Ruscher K., Lipski A., Jaenisch R., Moskowitz M.A., Dirnagl U. DNA methyltransferase contributes to delayed ischemic brain injury. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2000, 20:3175-3181.
7. Galea E., Glickstein S.B., Feinstein D.L., Golanov E.V., Reis D.J. Stimulation of cerebellar fastigial nucleus inhibits interleukin-1beta-induced cerebrovascular inflammation. The American Journal of Physiology 1998, 275:H2053-H2063.
8. Gupta M., Gupta S.K., Hoffman B., Liebermann D.A. Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition. The Journal of Biological Chemistry 2006, 281:17552-17558.
9. Iadecola C., Reis D.J. Continuous monitoring of cerebrocortical blood flow during stimulation of the cerebellar fastigial nucleus: a study by laser-Doppler flowmetry. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1990, 10:608-617.
10. Jin K., Chen J., Kawaguchi K., Zhu R.L., Stetler R.A., Simon R.P., Graham S.H. Focal ischemia induces expression of the DNA damage-inducible gene GADD45 in the rat brain. Neuroreport 1996, 7:1797-1802.
11. Liebermann D.A., Hoffman B. Gadd45 in the response of hematopoietic cells to genotoxic stress. Blood Cells, Molecules & Diseases 2007, 39:329-335.
12. Liu B., Suyeoka G., Papa S., Franzoso G., Neufeld A.H. Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries. Neurobiology of Disease 2009, 33:104-110.
13. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
14. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989, 20:84-91.
15. Ma D.K., Jang M.H., Guo J.U., Kitabatake Y., Chang M.L., Pow-Anpongkul N., Flavell R.A., Lu B., Ming G.L., Song H. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science. 2009, 323:1074-1077.
16. Miura M., Reis D.J. Cerebellum: a pressor response elicited from the fastigial nucleus and its efferent pathway in brainstem. Brain Research 1969, 13:595-599.
17. Montoya C.P., Campbell-Hope L.J., Pemberton K.D., Dunnett S.B. The" Staircase test": a measure of independent forelimb reaching and grasping abilities in rats. Journal of Neuroscience Methods 1991, 36:219-228.
18. Mraovitch S., Pinard E., Seylaz J. Two neural mechanisms in rat fastigial nucleus regulating systemic and cerebral circulation. The American Journal of Physiology 1986, 251:H153-H163.
19. Nakai M., Iadecola C., Reis D.J. Global cerebral vasodilation by stimulation of rat fastigial cerebellar nucleus. The American Journal of Physiology 1982, 243:H226-H235.
20. Nakai M., Iadecola C., Ruggiero D.A., Tucker L.W., Reis D.J. Electrical stimulation of cerebellar fastigial nucleus increases cerebral cortical blood flow without change in local metabolism: evidence for an intrinsic system in brain for primary vasodilation. Brain Research 1983, 260:35-49.
21. Reis D.J., Berger S.B., Underwood M.D., Khayata M. Electrical stimulation of cerebellar fastigial nucleus reduces ischemic infarction elicited by middle cerebral artery occlusion in rat. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1991, 11:810-818.
22. Reis D.J., Kobylarz K., Yamamoto S., Golanov E.V. Brief electrical stimulation of cerebellar fastigial nucleus conditions long-lasting salvage from focal cerebral ischemia: conditioned central neurogenic neuroprotection. Brain Research 1998, 780:161-165.
23. Williams J.L., Murray M.A., Schalk K.A., Heistad D.D. Cerebral blood flow during fastigial pressor response in cats. The American Journal of Physiology 1990, 258:H729-H733.
24. Yamamoto S., Golanov E.V., Reis D.J. Reductions in focal ischemic infarctions elicited from cerebellar fastigial nucleus do not result from elevations in cerebral blood flow. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1993, 13:1020-1024.
25. Yoo J., Ghiassi M., Jirmanova L., Balliet A.G., Hoffman B., Fornace A.J., Liebermann D.A., Bottinger E.P., Roberts A.B. Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation. The Journal of Biological Chemistry 2003, 278:43001-43007.
26. Zhang F., Iadecola C. Stimulation of the fastigial nucleus enhances EEG recovery and reduces tissue damage after focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1992, 2:962-970.
27. Zhang F., Iadecola C. Fastigial stimulation increases ischemic blood flow and reduces brain damage after focal ischemia. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 1993, 13:1013-1019.
28. Zhou P., Qian L., Glickstein S.B., Golanov E.V., Pickel V.M., Reis D.J. Electrical stimulation of cerebellar fastigial nucleus protects rat brain, in vitro, from staurosporine-induced apoptosis. Journal of Neurochemistry 2001, 79:328-338.