Tissue-specific responses of IGF-1/insulin and mTOR signaling in calorie restricted rats

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Sharma, Naveen ^a   Castorena, Carlos M ^a   Cartee, Gregory D ^a,b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; S6 KINASE; SERINE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TUBERIN; TYROSINE; MTOR PROTEIN, RAT; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CALORIC RESTRICTION; CEREBELLUM; CONTROLLED STUDY; DIETARY INTAKE; DOWN REGULATION; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; KIDNEY PARENCHYMA; LIVER; LUNG PARENCHYMA; MALE; MUSCLE TWITCH; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TISSUE SPECIFICITY; ANALYSIS OF VARIANCE; ANIMAL; GLUCOSE CLAMP TECHNIQUE; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS;

RATTUS; RATTUS NORVEGICUS;

ANALYSIS OF VARIANCE; ANIMALS; CALORIC RESTRICTION; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE CLAMP TECHNIQUE; IMMUNOBLOTTING; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MALE; METABOLIC NETWORKS AND PATHWAYS; MUSCLE, SKELETAL; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84862022050     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038835     Document Type: Article

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