-
1
-
-
0024460992
-
Endogenous oxidative DNA damage, aging, and cancer
-
Ames, B. N. (1989). Endogenous oxidative DNA damage, aging, and cancer. Free Radic. Res. Commun. 7, 121-128.
-
(1989)
Free Radic. Res. Commun.
, vol.7
, pp. 121-128
-
-
Ames, B.N.1
-
2
-
-
0030982145
-
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle
-
Aspnes, L. E., Lee, C. M., Weindruch, R., Chung, S. S., Roecker, E. B., and Aiken, J. M. (1997). Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. FASEB J. 11, 573-581.
-
(1997)
FASEB J.
, vol.11
, pp. 573-581
-
-
Aspnes, L.E.1
Lee, C.M.2
Weindruch, R.3
Chung, S.S.4
Roecker, E.B.5
Aiken, J.M.6
-
3
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman, K. B., and Ames, B. N. (1998). The free radical theory of aging matures. Physiol. Rev. 78, 547-581.
-
(1998)
Physiol. Rev.
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
4
-
-
0028856186
-
Factors influencing the repair and adaptation of muscles in aged individuals: Satellite cells and innervation
-
Carlson, B. M. (1995). Factors influencing the repair and adaptation of muscles in aged individuals: Satellite cells and innervation. J. Gerontol. A Biol. Sci. Med. Sci. 50, 96-100.
-
(1995)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.50
, pp. 96-100
-
-
Carlson, B.M.1
-
5
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance, B., Sies, H., and Boveris, A. (1979). Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59, 527-605.
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
6
-
-
0026592966
-
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions
-
Cheng, K. C., Cahill, D. S., Kasai, H., Nishimura, S., and Loeb, L. A. (1992). 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions. J. Biol. Chem. 267, 166-172.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 166-172
-
-
Cheng, K.C.1
Cahill, D.S.2
Kasai, H.3
Nishimura, S.4
Loeb, L.A.5
-
7
-
-
0031824031
-
The effect of dietary restriction on body composition in adult male and female rhesus macaques
-
Coleman, R. J., Roecker, E. B., Ramsey, J. J., and Kemnitz, J. W. (1998). The effect of dietary restriction on body composition in adult male and female rhesus macaques. Aging. (Milano) 10, 83-92.
-
(1998)
Aging. (Milano)
, vol.10
, pp. 83-92
-
-
Coleman, R.J.1
Roecker, E.B.2
Ramsey, J.J.3
Kemnitz, J.W.4
-
8
-
-
0031757854
-
Caloric restriction in rhesus monkeys reduces low-density-lipoprotein interaction with arterial proteoglycans
-
Edwards, I. J., Rudel, L. L., Terry, J. G., Kemnitz, J. W., Weindruch, R., and Cefalu, W. T. (1998). Caloric restriction in rhesus monkeys reduces low-density-lipoprotein interaction with arterial proteoglycans. J. Gerontol. A Biol. Sci. Med. Sci. 53, B443-448.
-
(1998)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.53
-
-
Edwards, I.J.1
Rudel, L.L.2
Terry, J.G.3
Kemnitz, J.W.4
Weindruch, R.5
Cefalu, W.T.6
-
9
-
-
0025127633
-
Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal
-
Esterbauer, H., and Cheeseman, K. H. (1990). Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186, 407-421.
-
(1990)
Methods Enzymol.
, vol.186
, pp. 407-421
-
-
Esterbauer, H.1
Cheeseman, K.H.2
-
10
-
-
0028849894
-
Muscle atrophy and weakness with aging: Contraction-induced injury as an underlying mechanism
-
Faulkner, J. A., Brooks, S. V., and Zerba, E. (1995). Muscle atrophy and weakness with aging: Contraction-induced injury as an underlying mechanism. J. Gerontol. Biol. A Sci. Med. Sci. 50, 124-129.
-
(1995)
J. Gerontol. Biol. A Sci. Med. Sci.
, vol.50
, pp. 124-129
-
-
Faulkner, J.A.1
Brooks, S.V.2
Zerba, E.3
-
12
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman, D. (1956). Aging: A theory based on free radical and radiation chemistry. J. Gerontol. 11, 298-300.
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
13
-
-
0015319592
-
The biological clock: The mitochondria?
-
Harman, D. (1972). The biological clock: The mitochondria? JAGS 20, 145-147.
-
(1972)
JAGS
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
14
-
-
0006793631
-
Experience with developing assays of physiological age
-
(M. E. Reff and E. L. Schneider, Eds), NIH Pub. #82-2221. U.S. Department of Health and Human Services, Washington, DC
-
Harrison, D. E. (1982). Experience with developing assays of physiological age. In Biological Markers of Aging (M. E. Reff and E. L. Schneider, Eds), pp. 2-12. NIH Pub. #82-2221. U.S. Department of Health and Human Services, Washington, DC.
-
(1982)
Biological Markers of Aging
, pp. 2-12
-
-
Harrison, D.E.1
-
15
-
-
0021048571
-
Physiological assays for biological age in mice: Relation of collagen, renal function, and longevity
-
Harrison, D. E., and Archer, J. R. (1983). Physiological assays for biological age in mice: Relation of collagen, renal function, and longevity. Exper. Aging Res. 9, 245-251.
-
(1983)
Exper. Aging Res.
, vol.9
, pp. 245-251
-
-
Harrison, D.E.1
Archer, J.R.2
-
16
-
-
0022556814
-
Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents
-
Kasai, H., and Nishimura, S. (1986). Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents. Environ. Health Perspect. 67, 111-116.
-
(1986)
Environ. Health Perspect.
, vol.67
, pp. 111-116
-
-
Kasai, H.1
Nishimura, S.2
-
17
-
-
0028301766
-
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys
-
Kemnitz, J. W., Roecker, E. B., Weindruch, R., Elson, D. F., Baum, S. T., and Bergman, R. N. (1994). Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am. J. Physiol. 266, E540-547.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Kemnitz, J.W.1
Roecker, E.B.2
Weindruch, R.3
Elson, D.F.4
Baum, S.T.5
Bergman, R.N.6
-
18
-
-
0027514561
-
Dietary restriction of adult male rhesus monkeys: Design, methodology, and preliminary findings from the first year of study
-
Kemnitz, J. W., Weindruch, R., Roecker, E. B., Crawford, K., Kaufman, P. L., and Ershler, W. B. (1993). Dietary restriction of adult male rhesus monkeys: Design, methodology, and preliminary findings from the first year of study. J. Gerontol. Biol. Sci. 48, B17-26.
-
(1993)
J. Gerontol. Biol. Sci.
, vol.48
-
-
Kemnitz, J.W.1
Weindruch, R.2
Roecker, E.B.3
Crawford, K.4
Kaufman, P.L.5
Ershler, W.B.6
-
19
-
-
0026781030
-
An emerging hypothesis: Synergistic induction of aging by free radicals and Maillard reactions
-
Kristal, B. A., and Yu, B. P. (1992). An emerging hypothesis: Synergistic induction of aging by free radicals and Maillard reactions. J. Gerontol. Biol. Sci. 47, B107-114.
-
(1992)
J. Gerontol. Biol. Sci.
, vol.47
-
-
Kristal, B.A.1
Yu, B.P.2
-
20
-
-
0027365312
-
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
-
Ku, H. H., Brunk, U. T., and Sohal, R. S. (1993). Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic. Biol. Med. 15, 621-627.
-
(1993)
Free Radic. Biol. Med.
, vol.15
, pp. 621-627
-
-
Ku, H.H.1
Brunk, U.T.2
Sohal, R.S.3
-
21
-
-
0028871820
-
Motor units: Remodeling in aged animals
-
Larsson, L. (1995). Motor units: remodeling in aged animals. J. Gerontol. A Biol. Sci. Med. Sci. 50, 91-95.
-
(1995)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.50
, pp. 91-95
-
-
Larsson, L.1
-
22
-
-
0032402945
-
Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria
-
in press
-
Lass A, Sohal, B. H., Weindruch R, Forster M. J., Sohal, R. S. (1998). Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic. Biol. Med. (in press).
-
(1998)
Free Radic. Biol. Med.
-
-
Lass, A.1
Sohal, B.H.2
Weindruch, R.3
Forster, M.J.4
Sohal, R.S.5
-
23
-
-
0032533691
-
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy
-
Lee, C. M., Lopez, M. E., Weindruch, R., and Aiken, J. M. (1998). Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic. Biol. Med. 25, 964-972.
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 964-972
-
-
Lee, C.M.1
Lopez, M.E.2
Weindruch, R.3
Aiken, J.M.4
-
24
-
-
0028291974
-
Carbonyl assays for determination of oxidatively modified proteins
-
Levine, R. L., Williams, J. A., Stadtman, E. R., and Shacter, E. (1994). Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 233, 346-357.
-
(1994)
Methods Enzymol.
, vol.233
, pp. 346-357
-
-
Levine, R.L.1
Williams, J.A.2
Stadtman, E.R.3
Shacter, E.4
-
25
-
-
0023856536
-
What is the cause of the ageing atrophy? Total number, size, and proportion of different fiber types studied in whole vastus lateralis muscle from 15-to 83-year-old men
-
Lexell, J., Sjostrom, M., Taylor, C. C., and (1988). What is the cause of the ageing atrophy? Total number, size, and proportion of different fiber types studied in whole vastus lateralis muscle from 15-to 83-year-old men. J. Neurol. Sci. 84, 275-294.
-
(1988)
J. Neurol. Sci.
, vol.84
, pp. 275-294
-
-
Lexell, J.1
Sjostrom, M.2
Taylor, C.C.3
-
26
-
-
0024340303
-
Dietary modulation of the progression of nephropathy in aging rats: An evaluation of the importance of protein
-
Masoro, E. J., Iwasaki, K., Gleiser, C. A., McMahan, C. A., Seo, E., and Yu, B. P. (1989). Dietary modulation of the progression of nephropathy in aging rats: An evaluation of the importance of protein. Am. J. Clin. Nutr. 49, 1217-1227.
-
(1989)
Am. J. Clin. Nutr.
, vol.49
, pp. 1217-1227
-
-
Masoro, E.J.1
Iwasaki, K.2
Gleiser, C.A.3
McMahan, C.A.4
Seo, E.5
Yu, B.P.6
-
27
-
-
0025864512
-
An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells
-
Miquel, J. (1991). An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells. Arch. Gerontol. Geriatr. 12, 99-117.
-
(1991)
Arch. Gerontol. Geriatr.
, vol.12
, pp. 99-117
-
-
Miquel, J.1
-
28
-
-
0028874567
-
Neuroendocrine involvement in aging: Evidence from studies of reproductive aging and caloric restriction
-
Nelson, J. F., Karelus, K., Bergman, M. D., and Felicio, L. S. (1995). Neuroendocrine involvement in aging: Evidence from studies of reproductive aging and caloric restriction. Neurobiol. Aging 16, 837-843.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 837-843
-
-
Nelson, J.F.1
Karelus, K.2
Bergman, M.D.3
Felicio, L.S.4
-
29
-
-
0028220114
-
Extension of life span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr, W. C., and Sohal, R. S. (1994). Extension of life span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
30
-
-
0030979002
-
Energy expenditure of adult male rhesus monkeys during the first 30 months of dietary restriction
-
Ramsey, J. J., Roecker, E. B., Weindruch, R., and Kemnitz, J. W. (1997). Energy expenditure of adult male rhesus monkeys during the first 30 months of dietary restriction. Am. J. Physiol. 272, E901-907.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Ramsey, J.J.1
Roecker, E.B.2
Weindruch, R.3
Kemnitz, J.W.4
-
31
-
-
0003894830
-
-
NIH Publication #82-2221. U.S. Department of Health and Human Services, Washington, DC
-
Reff, M. E., and Schneider, E. L. (1982). Biological Markers of Aging, NIH Publication #82-2221. U.S. Department of Health and Human Services, Washington, DC.
-
(1982)
Biological Markers of Aging
-
-
Reff, M.E.1
Schneider, E.L.2
-
32
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter, C., Park, J.-W., and Ames, B. N. (1988). Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. U S A 85, 6465-6467.
-
(1988)
Proc. Natl. Acad. Sci. U S A
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.-W.2
Ames, B.N.3
-
33
-
-
0021733969
-
Age changes in size and number of muscle fibers in human minor pectoral muscle
-
Sato, T., Akatsuka, H., Kuniyoshi, K., and Tokoro, Y. (1984). Age changes in size and number of muscle fibers in human minor pectoral muscle. Mech. Ageing Dev. 28, 99-109.
-
(1984)
Mech. Ageing Dev.
, vol.28
, pp. 99-109
-
-
Sato, T.1
Akatsuka, H.2
Kuniyoshi, K.3
Tokoro, Y.4
-
34
-
-
0029039854
-
Simultaneous overexpression of copper-and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosphila melanogaster
-
Sohal, R. S., Agarwal, A., Agarwal, S., and Orr, W. C. (1995). Simultaneous overexpression of copper-and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosphila melanogaster. J. Biol. Chem. 270, 15671-15674.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15671-15674
-
-
Sohal, R.S.1
Agarwal, A.2
Agarwal, S.3
Orr, W.C.4
-
35
-
-
0028116159
-
Effect of age and caloric restriction on DNA oxidative damage in different tissues of C56BL/6 mice
-
Sohal, R. S., Agarwal, S., Candas, M., Forster, M. J., and Lal, H. (1994a). Effect of age and caloric restriction on DNA oxidative damage in different tissues of C56BL/6 mice. Mech. Ageing Dev. 76, 215-224.
-
(1994)
Mech. Ageing Dev.
, vol.76
, pp. 215-224
-
-
Sohal, R.S.1
Agarwal, S.2
Candas, M.3
Forster, M.J.4
Lal, H.5
-
36
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation, and antioxidant defenses during aging, and in response to food restriction in the mouse
-
Sohal, R. S., Ku, H.-H., Agarwal, S., Forster, M. J., and Lal, H. (1994b). Oxidative damage, mitochondrial oxidant generation, and antioxidant defenses during aging, and in response to food restriction in the mouse. Mech. Ageing Dev. 74, 121-133.
-
(1994)
Mech. Ageing Dev.
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.-H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
37
-
-
0001354875
-
Is oxidative stress a causal factor in aging?
-
(K. Esser and G. M. Martin, Eds.), John Wiley & Sons, Ltd., New York
-
Sohal, R. S., and Orr, W. C. (1995). Is oxidative stress a causal factor in aging? In Molecular Aspects of Aging (K. Esser and G. M. Martin, Eds.), pp. 109-127. John Wiley & Sons, Ltd., New York.
-
(1995)
Molecular Aspects of Aging
, pp. 109-127
-
-
Sohal, R.S.1
Orr, W.C.2
-
38
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal, R. S., and Weindruch, R. (1996). Oxidative stress, caloric restriction, and aging. Science 273, 59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
39
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman, E. R. (1992). Protein oxidation and aging. Science 257, 1220-1224.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
40
-
-
0002452377
-
Gene expression and protein degradation
-
(E. J. Masoro, Ed.), Oxford University Press, New York
-
Van Remmen, H., Ward, W. F., Sabia, R. V., and Richardson, A. (1995). Gene expression and protein degradation. In Handbook of Physiology (E. J. Masoro, Ed.), pp. 171-234. Oxford University Press, New York.
-
(1995)
Handbook of Physiology
, pp. 171-234
-
-
Van Remmen, H.1
Ward, W.F.2
Sabia, R.V.3
Richardson, A.4
-
41
-
-
0030802101
-
The response to calorie restriction in mammals shows features also common to hibernation - A cross-adaptation hypothesis
-
Walford, R. L., and Spindler, S. R. (1997). The response to calorie restriction in mammals shows features also common to hibernation - a cross-adaptation hypothesis. J. Gerontol. A Biol. Sci. Med. Sci. 52, B179-183.
-
(1997)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.52
-
-
Walford, R.L.1
Spindler, S.R.2
-
42
-
-
0026587335
-
Mitochondrial genetics: A paradigm for aging and degenerative diseases?
-
Wallace, D. C. (1992). Mitochondrial genetics: A paradigm for aging and degenerative diseases? Science 256, 628-632.
-
(1992)
Science
, vol.256
, pp. 628-632
-
-
Wallace, D.C.1
-
43
-
-
0028856189
-
Interventions based on the possibility that oxidative stress contributes to sarcopenia
-
Weindruch, R. (1995). Interventions based on the possibility that oxidative stress contributes to sarcopenia. J. Gerontol. A Biol. Sci. Med Sci. 50, 157-161.
-
(1995)
J. Gerontol. A Biol. Sci. Med Sci.
, vol.50
, pp. 157-161
-
-
Weindruch, R.1
-
44
-
-
0019186034
-
Modification of mitochondrial respiration by aging and dietary restriction
-
Weindruch, R., Cheung, M. K., Verity, M. A., and Walford, R. L. (1980). Modification of mitochondrial respiration by aging and dietary restriction. Mech. Ageing Dev. 12, 375-392.
-
(1980)
Mech. Ageing Dev.
, vol.12
, pp. 375-392
-
-
Weindruch, R.1
Cheung, M.K.2
Verity, M.A.3
Walford, R.L.4
-
46
-
-
0020044308
-
Dietary restriction in mice beginning at one year of age: Effect on life span and spontaneous cancer incidence
-
Weindruch, R., and Walford, R. L. (1982). Dietary restriction in mice beginning at one year of age: Effect on life span and spontaneous cancer incidence. Science 215, 1415-1418.
-
(1982)
Science
, vol.215
, pp. 1415-1418
-
-
Weindruch, R.1
Walford, R.L.2
-
48
-
-
0003157159
-
Oxidative damage in free radicals and lipid peroxidation in aging
-
(B. P. Yu, Ed.), CRC Press, Boca Raton, FL
-
Yu, B. P. (1993). Oxidative damage in free radicals and lipid peroxidation in aging. In Free Radicals in Aging (B. P. Yu, Ed.), pp. 57-88. CRC Press, Boca Raton, FL.
-
(1993)
Free Radicals in Aging
, pp. 57-88
-
-
Yu, B.P.1
|