메뉴 건너뛰기




Volumn 30, Issue 30, 2012, Pages 4480-4489

Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for the creation of a live attenuated vaccine

Author keywords

Cross protective immunity; Influenza A virus; Live attenuated vaccine; Nucleoprotein (NP) gene; Silent mutation; Viral segment packaging

Indexed keywords

COMPLEMENTARY RNA; LIVE VACCINE; NEUTRALIZING ANTIBODY; NUCLEOPROTEIN; RECOMBINANT INFLUENZA VIRUS A VACCINE; RNA POLYMERASE; UNCLASSIFIED DRUG;

EID: 84862017919     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.04.070     Document Type: Article
Times cited : (9)

References (45)
  • 1
    • 0032516267 scopus 로고    scopus 로고
    • The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children
    • May
    • Belshe R.B., Mendelman P.M., Treanor J., King J., Gruber W.C., Piedra P., et al. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. New England Journal of Medicine 1998, 338(May (20)):1405-1412.
    • (1998) New England Journal of Medicine , vol.338 , Issue.20 , pp. 1405-1412
    • Belshe, R.B.1    Mendelman, P.M.2    Treanor, J.3    King, J.4    Gruber, W.C.5    Piedra, P.6
  • 2
    • 0037293142 scopus 로고    scopus 로고
    • Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60
    • February
    • Jin H., Lu B., Zhou H., Ma C., Zhao J., Yang C.F., et al. Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60. Virology 2003, 306(February (1)):18-24.
    • (2003) Virology , vol.306 , Issue.1 , pp. 18-24
    • Jin, H.1    Lu, B.2    Zhou, H.3    Ma, C.4    Zhao, J.5    Yang, C.F.6
  • 3
    • 53249143947 scopus 로고    scopus 로고
    • Molecular studies of temperature-sensitive replication of the cold-adapted B/Ann Arbor/1/66, the master donor virus for live attenuated influenza FluMist vaccines
    • October
    • Chen Z., Aspelund A., Kemble G., Jin H. Molecular studies of temperature-sensitive replication of the cold-adapted B/Ann Arbor/1/66, the master donor virus for live attenuated influenza FluMist vaccines. Virology 2008, 380(October (2)):354-362.
    • (2008) Virology , vol.380 , Issue.2 , pp. 354-362
    • Chen, Z.1    Aspelund, A.2    Kemble, G.3    Jin, H.4
  • 4
    • 0022486360 scopus 로고
    • Study of live recombinant cold-adapted influenza bivalent vaccine of type A for use in children: an epidemiological control trial
    • June
    • Alexandrova G.I., Budilovsky G.N., Koval T.A., Polezhaev F.I., Garmashova L.M., Ghendon Yu Z., et al. Study of live recombinant cold-adapted influenza bivalent vaccine of type A for use in children: an epidemiological control trial. Vaccine 1986, 4(June (2)):114-118.
    • (1986) Vaccine , vol.4 , Issue.2 , pp. 114-118
    • Alexandrova, G.I.1    Budilovsky, G.N.2    Koval, T.A.3    Polezhaev, F.I.4    Garmashova, L.M.5    Ghendon Yu, Z.6
  • 5
    • 20944449865 scopus 로고    scopus 로고
    • A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutinin
    • June
    • Stech J., Garn H., Wegmann M., Wagner R., Klenk H.D. A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutinin. Nature Medicine 2005, 11(June (6)):683-689.
    • (2005) Nature Medicine , vol.11 , Issue.6 , pp. 683-689
    • Stech, J.1    Garn, H.2    Wegmann, M.3    Wagner, R.4    Klenk, H.D.5
  • 7
    • 75649127312 scopus 로고    scopus 로고
    • A novel type of influenza vaccine: safety and immunogenicity of replication-deficient influenza virus created by deletion of the interferon antagonist NS1
    • Wacheck V., Egorov A., Groiss F., Pfeiffer A., Fuereder T., Hoeflmayer D., et al. A novel type of influenza vaccine: safety and immunogenicity of replication-deficient influenza virus created by deletion of the interferon antagonist NS1. Journal of Infectious Diseases 2010, 201(3):354-362.
    • (2010) Journal of Infectious Diseases , vol.201 , Issue.3 , pp. 354-362
    • Wacheck, V.1    Egorov, A.2    Groiss, F.3    Pfeiffer, A.4    Fuereder, T.5    Hoeflmayer, D.6
  • 9
    • 79953140161 scopus 로고    scopus 로고
    • Disruption of the viral polymerase complex assembly as a novel approach to attenuate influenza A virus
    • March
    • Manz B., Gotz V., Wunderlich K., Eisel J., Kirchmair J., Stech J., et al. Disruption of the viral polymerase complex assembly as a novel approach to attenuate influenza A virus. Journal of Biological Chemistry 2011, 286(March (10)):8414-8424.
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.10 , pp. 8414-8424
    • Manz, B.1    Gotz, V.2    Wunderlich, K.3    Eisel, J.4    Kirchmair, J.5    Stech, J.6
  • 10
    • 79951812356 scopus 로고    scopus 로고
    • An M2 cytoplasmic tail mutant as a live attenuated influenza vaccine against pandemic (H1N1) 2009 influenza virus
    • March
    • Hatta Y., Hatta M., Bilsel P., Neumann G., Kawaoka Y. An M2 cytoplasmic tail mutant as a live attenuated influenza vaccine against pandemic (H1N1) 2009 influenza virus. Vaccine 2011, 29(March (12)):2308-2312.
    • (2011) Vaccine , vol.29 , Issue.12 , pp. 2308-2312
    • Hatta, Y.1    Hatta, M.2    Bilsel, P.3    Neumann, G.4    Kawaoka, Y.5
  • 12
    • 31444441789 scopus 로고    scopus 로고
    • Architecture of ribonucleoprotein complexes in influenza A virus particles
    • January
    • Noda T., Sagara H., Yen A., Takada A., Kida H., Cheng R.H., et al. Architecture of ribonucleoprotein complexes in influenza A virus particles. Nature 2006, 439(January (7075)):490-492.
    • (2006) Nature , vol.439 , Issue.7075 , pp. 490-492
    • Noda, T.1    Sagara, H.2    Yen, A.3    Takada, A.4    Kida, H.5    Cheng, R.H.6
  • 14
    • 70349970792 scopus 로고    scopus 로고
    • Characterisation of influenza A viruses with mutations in segment 5 packaging signals
    • October
    • Hutchinson E.C., Wise H.M., Kudryavtseva K., Curran M.D., Digard P. Characterisation of influenza A viruses with mutations in segment 5 packaging signals. Vaccine 2009, 27(October (45)):6270-6275.
    • (2009) Vaccine , vol.27 , Issue.45 , pp. 6270-6275
    • Hutchinson, E.C.1    Wise, H.M.2    Kudryavtseva, K.3    Curran, M.D.4    Digard, P.5
  • 15
    • 0025951699 scopus 로고
    • An influenza virus containing nine different RNA segments
    • November
    • Enami M., Sharma G., Benham C., Palese P. An influenza virus containing nine different RNA segments. Virology 1991, 185(November (1)):291-298.
    • (1991) Virology , vol.185 , Issue.1 , pp. 291-298
    • Enami, M.1    Sharma, G.2    Benham, C.3    Palese, P.4
  • 16
    • 0036635529 scopus 로고    scopus 로고
    • Evidence for segment-nonspecific packaging of the influenza a virus genome
    • July
    • Bancroft C.T., Parslow T.G. Evidence for segment-nonspecific packaging of the influenza a virus genome. Journal of Virology 2002, 76(July (14)):7133-7139.
    • (2002) Journal of Virology , vol.76 , Issue.14 , pp. 7133-7139
    • Bancroft, C.T.1    Parslow, T.G.2
  • 17
    • 77954980813 scopus 로고    scopus 로고
    • A nine-segment influenza a virus carrying subtype H1 and H3 hemagglutinins
    • August
    • Gao Q., Lowen A.C., Wang T.T., Palese P. A nine-segment influenza a virus carrying subtype H1 and H3 hemagglutinins. Journal of Virology 2010, 84(August (16)):8062-8071.
    • (2010) Journal of Virology , vol.84 , Issue.16 , pp. 8062-8071
    • Gao, Q.1    Lowen, A.C.2    Wang, T.T.3    Palese, P.4
  • 18
    • 23244467786 scopus 로고    scopus 로고
    • Cis-Acting packaging signals in the influenza virus PB1, PB2, and PA genomic RNA segments
    • August
    • Liang Y., Hong Y., Parslow T.G. cis-Acting packaging signals in the influenza virus PB1, PB2, and PA genomic RNA segments. Journal of Virology 2005, 79(August (16)):10348-10355.
    • (2005) Journal of Virology , vol.79 , Issue.16 , pp. 10348-10355
    • Liang, Y.1    Hong, Y.2    Parslow, T.G.3
  • 20
    • 84863393147 scopus 로고    scopus 로고
    • A supramolecular assembly formed by influenza A virus genomic RNA segments
    • [Nov 10; Epub ahead of print]
    • Fournier E., Moules V., Essere B., Paillart J.C., Sirbat J.D., Isel C., et al. A supramolecular assembly formed by influenza A virus genomic RNA segments. Nucleic Acids Res 2011, [Nov 10; Epub ahead of print].
    • (2011) Nucleic Acids Res
    • Fournier, E.1    Moules, V.2    Essere, B.3    Paillart, J.C.4    Sirbat, J.D.5    Isel, C.6
  • 21
    • 33845724694 scopus 로고    scopus 로고
    • Contributions of two nuclear localization signals of influenza A virus nucleoprotein to viral replication
    • January
    • Ozawa M., Fujii K., Muramoto Y., Yamada S., Yamayoshi S., Takada A., et al. Contributions of two nuclear localization signals of influenza A virus nucleoprotein to viral replication. Journal of Virology 2007, 81(January (1)):30-41.
    • (2007) Journal of Virology , vol.81 , Issue.1 , pp. 30-41
    • Ozawa, M.1    Fujii, K.2    Muramoto, Y.3    Yamada, S.4    Yamayoshi, S.5    Takada, A.6
  • 22
    • 14744274632 scopus 로고    scopus 로고
    • Importance of both the coding and the segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions
    • March
    • Fujii K., Fujii Y., Noda T., Muramoto Y., Watanabe T., Takada A., et al. Importance of both the coding and the segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions. Journal of Virology 2005, 79(March (6)):3766-3774.
    • (2005) Journal of Virology , vol.79 , Issue.6 , pp. 3766-3774
    • Fujii, K.1    Fujii, Y.2    Noda, T.3    Muramoto, Y.4    Watanabe, T.5    Takada, A.6
  • 23
    • 35348814973 scopus 로고    scopus 로고
    • Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions
    • September
    • Marsh G.A., Hatami R., Palese P. Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions. Journal of Virology 2007, 81(September (18)):9727-9736.
    • (2007) Journal of Virology , vol.81 , Issue.18 , pp. 9727-9736
    • Marsh, G.A.1    Hatami, R.2    Palese, P.3
  • 24
    • 81555205766 scopus 로고    scopus 로고
    • Taming influenza viruses
    • December
    • Ozawa M., Kawaoka Y. Taming influenza viruses. Virus Research 2011, 162(December (1-2)):8-11.
    • (2011) Virus Research , vol.162 , Issue.1-2 , pp. 8-11
    • Ozawa, M.1    Kawaoka, Y.2
  • 25
    • 0029554432 scopus 로고
    • Molecular evolution of influenza viruses
    • Scholtissek C. Molecular evolution of influenza viruses. Virus Genes 1995, 11(2-3):209-215.
    • (1995) Virus Genes , vol.11 , Issue.2-3 , pp. 209-215
    • Scholtissek, C.1
  • 26
    • 0036210827 scopus 로고    scopus 로고
    • The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication
    • April
    • Portela A., Digard P. The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. Journal of General Virology 2002, 83(April (Pt 4)):723-734.
    • (2002) Journal of General Virology , vol.83 , Issue.PART 4 , pp. 723-734
    • Portela, A.1    Digard, P.2
  • 27
    • 37849052232 scopus 로고    scopus 로고
    • The influenza virus resource at the National Center for Biotechnology Information
    • January
    • Bao Y., Bolotov P., Dernovoy D., Kiryutin B., Zaslavsky L., Tatusova T., et al. The influenza virus resource at the National Center for Biotechnology Information. Journal of Virology 2008, 82(January (2)):596-601.
    • (2008) Journal of Virology , vol.82 , Issue.2 , pp. 596-601
    • Bao, Y.1    Bolotov, P.2    Dernovoy, D.3    Kiryutin, B.4    Zaslavsky, L.5    Tatusova, T.6
  • 29
    • 0035815684 scopus 로고    scopus 로고
    • Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway
    • June
    • Ludwig S., Ehrhardt C., Neumeier E.R., Kracht M., Rapp U.R., Pleschka S. Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway. Journal of Biological Chemistry 2001, 276(June (24)):10990-10998.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.24 , pp. 10990-10998
    • Ludwig, S.1    Ehrhardt, C.2    Neumeier, E.R.3    Kracht, M.4    Rapp, U.R.5    Pleschka, S.6
  • 30
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • May
    • Reed L.J., Muench H. A simple method of estimating fifty per cent endpoints. American Journal of Epidemiology 1938, 27(May (3)):493-497.
    • (1938) American Journal of Epidemiology , vol.27 , Issue.3 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 31
    • 84555178398 scopus 로고    scopus 로고
    • Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice
    • January
    • Seyer R., Hrincius E.R., Ritzel D., Abt M., Mellmann A., Marjuki H., et al. Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice. Journal of Infectious Diseases 2012, 205(January (2)):262-271.
    • (2012) Journal of Infectious Diseases , vol.205 , Issue.2 , pp. 262-271
    • Seyer, R.1    Hrincius, E.R.2    Ritzel, D.3    Abt, M.4    Mellmann, A.5    Marjuki, H.6
  • 32
    • 78650063715 scopus 로고    scopus 로고
    • T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model
    • January
    • Guo H., Santiago F., Lambert K., Takimoto T., Topham D.J. T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model. Journal of Virology 2011, 85(January (1)):448-455.
    • (2011) Journal of Virology , vol.85 , Issue.1 , pp. 448-455
    • Guo, H.1    Santiago, F.2    Lambert, K.3    Takimoto, T.4    Topham, D.J.5
  • 34
    • 78649476854 scopus 로고    scopus 로고
    • Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development
    • November
    • Stanekova Z., Vareckova E. Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development. Virology Journal 2010, (November):351.
    • (2010) Virology Journal , pp. 351
    • Stanekova, Z.1    Vareckova, E.2
  • 35
    • 81555228636 scopus 로고    scopus 로고
    • Novel vaccines against influenza viruses
    • December
    • Kang S.M., Song J.M., Compans R.W. Novel vaccines against influenza viruses. Virus Research 2011, 162(December (1-2)):31-38.
    • (2011) Virus Research , vol.162 , Issue.1-2 , pp. 31-38
    • Kang, S.M.1    Song, J.M.2    Compans, R.W.3
  • 36
    • 0025237152 scopus 로고
    • Evolution of the nucleoprotein gene of influenza A virus
    • April
    • Gorman O.T., Bean W.J., Kawaoka Y., Webster R.G. Evolution of the nucleoprotein gene of influenza A virus. Journal of Virology 1990, 64(April (4)):1487-1497.
    • (1990) Journal of Virology , vol.64 , Issue.4 , pp. 1487-1497
    • Gorman, O.T.1    Bean, W.J.2    Kawaoka, Y.3    Webster, R.G.4
  • 37
    • 0027346651 scopus 로고
    • Analysis of influenza A virus nucleoproteins for the assessment of molecular genetic mechanisms leading to new phylogenetic virus lineages
    • Scholtissek C., Ludwig S., Fitch W.M. Analysis of influenza A virus nucleoproteins for the assessment of molecular genetic mechanisms leading to new phylogenetic virus lineages. Archives of Virology 1993, 131(3-4):237-250.
    • (1993) Archives of Virology , vol.131 , Issue.3-4 , pp. 237-250
    • Scholtissek, C.1    Ludwig, S.2    Fitch, W.M.3
  • 38
    • 84863720723 scopus 로고    scopus 로고
    • Return of inactivated whole-virus vaccine for superior efficacy
    • August
    • Furuya Y. Return of inactivated whole-virus vaccine for superior efficacy. Immunology and Cell Biology 2011, (August).
    • (2011) Immunology and Cell Biology
    • Furuya, Y.1
  • 39
    • 56449098772 scopus 로고    scopus 로고
    • Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus
    • December
    • Hutchinson E.C., Curran M.D., Read E.K., Gog J.R., Digard P. Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. Journal of Virology 2008, 82(December (23)):11869-11879.
    • (2008) Journal of Virology , vol.82 , Issue.23 , pp. 11869-11879
    • Hutchinson, E.C.1    Curran, M.D.2    Read, E.K.3    Gog, J.R.4    Digard, P.5
  • 40
    • 0031568653 scopus 로고    scopus 로고
    • MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL
    • February
    • Deng Y., Yewdell J.W., Eisenlohr L.C., Bennink J.R. MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. Journal of Immunology 1997, 158(February (4)):1507-1515.
    • (1997) Journal of Immunology , vol.158 , Issue.4 , pp. 1507-1515
    • Deng, Y.1    Yewdell, J.W.2    Eisenlohr, L.C.3    Bennink, J.R.4
  • 41
    • 80052755593 scopus 로고    scopus 로고
    • Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections
    • October
    • Ludwig S. Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections. Biological Chemistry 2011, 392(October (10)):837-847.
    • (2011) Biological Chemistry , vol.392 , Issue.10 , pp. 837-847
    • Ludwig, S.1
  • 42
    • 77954171801 scopus 로고    scopus 로고
    • Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice
    • July
    • Bodewes R., Kreijtz J.H., Hillaire M.L., Geelhoed-Mieras M.M., Fouchier R.A., Osterhaus A.D., et al. Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice. Journal of General Virology 2010, 91(July (Pt 7)):1743-1753.
    • (2010) Journal of General Virology , vol.91 , Issue.PART 7 , pp. 1743-1753
    • Bodewes, R.1    Kreijtz, J.H.2    Hillaire, M.L.3    Geelhoed-Mieras, M.M.4    Fouchier, R.A.5    Osterhaus, A.D.6
  • 43
    • 79952404440 scopus 로고    scopus 로고
    • Vaccination against seasonal influenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infection in ferrets
    • March
    • Bodewes R., Kreijtz J.H., Geelhoed-Mieras M.M., van Amerongen G., Verburgh R.J., van Trierum S.E., et al. Vaccination against seasonal influenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infection in ferrets. Journal of Virology 2011, 85(March (6)):2695-2702.
    • (2011) Journal of Virology , vol.85 , Issue.6 , pp. 2695-2702
    • Bodewes, R.1    Kreijtz, J.H.2    Geelhoed-Mieras, M.M.3    van Amerongen, G.4    Verburgh, R.J.5    van Trierum, S.E.6
  • 44
    • 33846204394 scopus 로고    scopus 로고
    • Evidence for specific packaging of the influenza A virus genome from conditionally defective virus particles lacking a polymerase gene
    • November
    • de Wit E., Spronken M.I., Rimmelzwaan G.F., Osterhaus A.D., Fouchier R.A. Evidence for specific packaging of the influenza A virus genome from conditionally defective virus particles lacking a polymerase gene. Vaccine 2006, 24(November (44-46)):6647-6650.
    • (2006) Vaccine , vol.24 , Issue.44-46 , pp. 6647-6650
    • de Wit, E.1    Spronken, M.I.2    Rimmelzwaan, G.F.3    Osterhaus, A.D.4    Fouchier, R.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.