-
2
-
-
65449161780
-
2009 Alzheimer's disease facts and figures
-
Alzheimer's Association
-
Alzheimer's Association, (2009) 2009 Alzheimer's disease facts and figures. Alzheimers Dement. 5 (3): 234-270.
-
(2009)
Alzheimers Dement
, vol.5
, Issue.3
, pp. 234-270
-
-
-
3
-
-
77949875590
-
Interleukin-6 as a therapeutic target in candidate inflammatory diseases
-
Nishimoto N, (2010) Interleukin-6 as a therapeutic target in candidate inflammatory diseases. Clin Pharmacol Ther. 87 (4): 483-7.
-
(2010)
Clin Pharmacol Ther
, vol.87
, Issue.4
, pp. 483-487
-
-
Nishimoto, N.1
-
4
-
-
0036959504
-
Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease
-
Ge YW, Lahiri DK, (2002) Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease. Ann N Y Acad Sci. 973: 463-7.
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 463-467
-
-
Ge, Y.W.1
Lahiri, D.K.2
-
5
-
-
34548555711
-
Genetics of Alzheimer's disease. A rapidly evolving field
-
Serretti A, Olgiati P, De Ronchi D, (2007) Genetics of Alzheimer's disease. A rapidly evolving field. J Alzheimers Dis. 12 (1): 73-92.
-
(2007)
J Alzheimers Dis
, vol.12
, Issue.1
, pp. 73-92
-
-
Serretti, A.1
Olgiati, P.2
De Ronchi, D.3
-
6
-
-
33947695600
-
Additive effect of interleukin-6 and C-reactive protein (CRP) single nucleotide polymorphism on serum CRP concentration and other cardiovascular risk factors
-
Paik JK, Kim OY, Koh SJ, Jang Y, Chae JS, et al. (2007) Additive effect of interleukin-6 and C-reactive protein (CRP) single nucleotide polymorphism on serum CRP concentration and other cardiovascular risk factors.Clin Chim Acta. 380 (1-2): 68-74.
-
(2007)
Clin Chim Acta
, vol.380
, Issue.1-2
, pp. 68-74
-
-
Paik, J.K.1
Kim, O.Y.2
Koh, S.J.3
Jang, Y.4
Chae, J.S.5
-
7
-
-
34848822828
-
Plasma levels of fibrinogen and C-reactive protein are related to interleukin-6 gene -572C >G polymorphism in subjects with and without hypertension
-
Wong LY, Leung RY, Ong KL, Cheung BM, (2007) Plasma levels of fibrinogen and C-reactive protein are related to interleukin-6 gene -572C >G polymorphism in subjects with and without hypertension. J Hum Hypertens. 21: 875-82.
-
(2007)
J Hum Hypertens
, vol.21
, pp. 875-882
-
-
Wong, L.Y.1
Leung, R.Y.2
Ong, K.L.3
Cheung, B.M.4
-
8
-
-
77953542774
-
Association between interleukin-6 gene promoter -572C/G polymorphism and the risk of sporadic Alzheimer's disease
-
He MX, Yang WL, Zhang MM, Lian YJ, Hua HY, et al. (2010) Association between interleukin-6 gene promoter -572C/G polymorphism and the risk of sporadic Alzheimer's disease. Neurol Sci. 31: 165-8.
-
(2010)
Neurol Sci
, vol.31
, pp. 165-168
-
-
He, M.X.1
Yang, W.L.2
Zhang, M.M.3
Lian, Y.J.4
Hua, H.Y.5
-
9
-
-
4444324424
-
Influence of polymorphisms in the genes for cytokines and glutathione S-transferase omega on sporadic Alzheimer's disease
-
Nishimura M, Sakamoto T, Kaji R, Kawakami H, (2004) Influence of polymorphisms in the genes for cytokines and glutathione S-transferase omega on sporadic Alzheimer's disease. Neurosci. Lett. 368: 140-3.
-
(2004)
Neurosci. Lett
, vol.368
, pp. 140-143
-
-
Nishimura, M.1
Sakamoto, T.2
Kaji, R.3
Kawakami, H.4
-
10
-
-
79951565767
-
Associations of gene sequence variation and serum levels of C-reactive protein and interleukin-6 with Alzheimer's disease and dementia
-
Eriksson UK, Pedersen N, Reynolds CA, Hong MG, Prince JA, et al. (2011) Associations of gene sequence variation and serum levels of C-reactive protein and interleukin-6 with Alzheimer's disease and dementia. Journal of Alzheimer's Disease. 23: 1-3.
-
(2011)
Journal of Alzheimer's Disease
, vol.23
, pp. 1-3
-
-
Eriksson, U.K.1
Pedersen, N.2
Reynolds, C.A.3
Hong, M.G.4
Prince, J.A.5
-
11
-
-
77955918642
-
The interleukin-6 gene -572C/G promoter polymorphism modifies Alzheimer's risk in APOEε4 carriers
-
Wang M, Jia J, (2010) The interleukin-6 gene -572C/G promoter polymorphism modifies Alzheimer's risk in APOEε4 carriers. Neuroscience Letters. 482: 260-3.
-
(2010)
Neuroscience Letters
, vol.482
, pp. 260-263
-
-
Wang, M.1
Jia, J.2
-
12
-
-
84856069957
-
Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease
-
[Epub ahead of print]
-
Chen SY, Chen TF, Lai LC, Chen JH, Sun Y, et al. (2012) Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease. J Neuroinflammation. 9(1) 21. [Epub ahead of print].
-
(2012)
J Neuroinflammation
, vol.9
, Issue.1
, pp. 21
-
-
Chen, S.Y.1
Chen, T.F.2
Lai, L.C.3
Chen, J.H.4
Sun, Y.5
-
13
-
-
84862565488
-
Association between polymorphism in the promoter region of Interleukin 6 (-174 G/C) and risk of Alzheimer's disease: a meta-analysis
-
[Epub ahead of print]
-
Dai L, Liu D, Guo H, Wang Y, Bai Y, (2011) Association between polymorphism in the promoter region of Interleukin 6 (-174 G/C) and risk of Alzheimer's disease: a meta-analysis. J Neurol. [Epub ahead of print].
-
(2011)
J Neurol
-
-
Dai, L.1
Liu, D.2
Guo, H.3
Wang, Y.4
Bai, Y.5
-
14
-
-
80053448176
-
Interleukin-6-174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: A meta-analysis
-
Han XM, Wang CH, Sima X, Liu SY, (2011) Interleukin-6-174G/C polymorphism and the risk of Alzheimer's disease in Caucasians: A meta-analysis. Neurosci Lett. 504 (1): 4-8.
-
(2011)
Neurosci Lett
, vol.504
, Issue.1
, pp. 4-8
-
-
Han, X.M.1
Wang, C.H.2
Sima, X.3
Liu, S.Y.4
-
15
-
-
0032914896
-
A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
-
Papassotiropoulos A, Bagli M, Jessen F, Bayer TA, Maier W, et al. (1999) A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease. Ann Neurol. 45 (5): 666-8.
-
(1999)
Ann Neurol
, vol.45
, Issue.5
, pp. 666-668
-
-
Papassotiropoulos, A.1
Bagli, M.2
Jessen, F.3
Bayer, T.A.4
Maier, W.5
-
16
-
-
4644319999
-
Gene-gene interaction between interleukin-6 and interleukin-10 reduces AD risk
-
Infante J, Sanz C, Fernández-Luna JT, Llorca J, Berciano J, et al. (2004) Gene-gene interaction between interleukin-6 and interleukin-10 reduces AD risk. Neurology. 63 (6): 1135-6.
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1135-1136
-
-
Infante, J.1
Sanz, C.2
Fernández-Luna, J.T.3
Llorca, J.4
Berciano, J.5
-
17
-
-
17744380686
-
Interaction between interleukin-6 and intercellular adhesion molecule-1 genes and Alzheimer's disease risk
-
Combarros O, Infante J, Llorca J, Peña N, Fernández-Viadero C, et al. (2005) Interaction between interleukin-6 and intercellular adhesion molecule-1 genes and Alzheimer's disease risk. J Neurol. 252: 485-7.
-
(2005)
J Neurol
, vol.252
, pp. 485-487
-
-
Combarros, O.1
Infante, J.2
Llorca, J.3
Peña, N.4
Fernández-Viadero, C.5
-
18
-
-
67650459139
-
Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk
-
Fontalba A, Gutiérrez O, Llorca J, Mateo I, Mateo I, et al. (2009) Gene-gene interaction between CARD8 and interleukin-6 reduces Alzheimer's disease risk. J Neurol. 256 (7): 1184-6.
-
(2009)
J Neurol
, vol.256
, Issue.7
, pp. 1184-1186
-
-
Fontalba, A.1
Gutiérrez, O.2
Llorca, J.3
Mateo, I.4
Mateo, I.5
-
19
-
-
32344443997
-
Interaction between dopamine beta-hydroxylase and interleukin genes increases Alzheimer's disease risk
-
Mateo I, Infante J, Rodríguez E, Berciano J, Combarros O, et al. (2006) Interaction between dopamine beta-hydroxylase and interleukin genes increases Alzheimer's disease risk. J Neurol Neurosurg Psychiatry. 77 (2): 278-9.
-
(2006)
J Neurol Neurosurg Psychiatry
, vol.77
, Issue.2
, pp. 278-279
-
-
Mateo, I.1
Infante, J.2
Rodríguez, E.3
Berciano, J.4
Combarros, O.5
-
20
-
-
0034616230
-
Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population
-
Bagli M, Papassotiropoulos A, Knapp M, Jessen F, Luise Rao M, et al. (2000) Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population. Neurosci Lett. 283 (2): 109-12.
-
(2000)
Neurosci Lett
, vol.283
, Issue.2
, pp. 109-112
-
-
Bagli, M.1
Papassotiropoulos, A.2
Knapp, M.3
Jessen, F.4
Luise Rao, M.5
-
21
-
-
0034617348
-
Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease
-
Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI, (2000) Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease. Neurosci Lett. 288 (1): 21-4.
-
(2000)
Neurosci Lett
, vol.288
, Issue.1
, pp. 21-24
-
-
Bhojak, T.J.1
DeKosky, S.T.2
Ganguli, M.3
Kamboh, M.I.4
-
22
-
-
2942755836
-
Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer's disease
-
Arosio B, Trabattoni D, Galimberti L, Bucciarelli P, Fasano F, et al. (2004) Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer's disease. Neurobiol Aging. 25 (8): 1009-15.
-
(2004)
Neurobiol Aging
, vol.25
, Issue.8
, pp. 1009-1015
-
-
Arosio, B.1
Trabattoni, D.2
Galimberti, L.3
Bucciarelli, P.4
Fasano, F.5
-
23
-
-
6944229787
-
Interleukin 6-174 G/C promoter gene polymorphism and sporadic Alzheimer's disease: geographic allele and genotype variations in Europe
-
Capurso C, Solfrizzi V, D'Introno A, Colacicco AM, Capurso SA, et al. (2004) Interleukin 6-174 G/C promoter gene polymorphism and sporadic Alzheimer's disease: geographic allele and genotype variations in Europe. Exp Gerontol. 39 (10): 1567-73.
-
(2004)
Exp Gerontol
, vol.39
, Issue.10
, pp. 1567-1573
-
-
Capurso, C.1
Solfrizzi, V.2
D'Introno, A.3
Colacicco, A.M.4
Capurso, S.A.5
-
24
-
-
73649085771
-
Interleukin 6-174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease
-
Capurso C, Solfrizzi V, Colacicco AM, D'Introno A, Frisardi V, et al. (2010) Interleukin 6-174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry. 34: 177-82.
-
(2010)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.34
, pp. 177-182
-
-
Capurso, C.1
Solfrizzi, V.2
Colacicco, A.M.3
D'Introno, A.4
Frisardi, V.5
-
25
-
-
1542614529
-
An interleukin-6 promoter variant is not associated with an increased risk for Alzheimer's disease
-
Depboylu C, Lohmüller F, Gocke P, Du Y, Zimmer R, et al. (2004) An interleukin-6 promoter variant is not associated with an increased risk for Alzheimer's disease. Dement Geriatr Cogn Disord. 17 (3): 170-3.
-
(2004)
Dement Geriatr Cogn Disord
, vol.17
, Issue.3
, pp. 170-173
-
-
Depboylu, C.1
Lohmüller, F.2
Gocke, P.3
Du, Y.4
Zimmer, R.5
-
26
-
-
0345269140
-
Interleukin-6-174 G/C promoter gene polymorphism C allele reduces Alzheimer's disease risk
-
Faltraco F, Bürger K, Zill P, Teipel SJ, Möller HJ, et al. (2003) Interleukin-6-174 G/C promoter gene polymorphism C allele reduces Alzheimer's disease risk. J Am Geriatr Soc. 51 (4): 578-9.
-
(2003)
J Am Geriatr Soc
, vol.51
, Issue.4
, pp. 578-579
-
-
Faltraco, F.1
Bürger, K.2
Zill, P.3
Teipel, S.J.4
Möller, H.J.5
-
27
-
-
33645037988
-
Interleukin-6 promoter polymorphism and late-onset Alzheimer's disease in the Finnish population
-
Koivisto AM, Helisalmi S, Pihlajamäki J, Moilanen L, et al. (2005) Interleukin-6 promoter polymorphism and late-onset Alzheimer's disease in the Finnish population. J Neurogenet. 19 (3-4): 155-61.
-
(2005)
J Neurogenet
, vol.19
, Issue.3-4
, pp. 155-161
-
-
Koivisto, A.M.1
Helisalmi, S.2
Pihlajamäki, J.3
Moilanen, L.4
-
28
-
-
0043092123
-
Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain
-
Licastro F, Grimaldi LM, Bonafè M, Martina C, Olivieri F, et al. (2003) Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging. 24 (7): 921-6.
-
(2003)
Neurobiol Aging
, vol.24
, Issue.7
, pp. 921-926
-
-
Licastro, F.1
Grimaldi, L.M.2
Bonafè, M.3
Martina, C.4
Olivieri, F.5
-
29
-
-
79251503004
-
IL-6-174 G/C and ApoE gene polymorphisms in Alzheimer's and vascular dementia patients attending the cognitive disorder clinic of the All India Institute of Medical Sciences, New Delhi
-
Mansoori N, Tripathi M, Alam R, Luthra K, Ramakrishnan L, et al. (2010) IL-6-174 G/C and ApoE gene polymorphisms in Alzheimer's and vascular dementia patients attending the cognitive disorder clinic of the All India Institute of Medical Sciences, New Delhi. Dement Geriatr Cogn Disord. 30 (6): 461-8.
-
(2010)
Dement Geriatr Cogn Disord
, vol.30
, Issue.6
, pp. 461-468
-
-
Mansoori, N.1
Tripathi, M.2
Alam, R.3
Luthra, K.4
Ramakrishnan, L.5
-
30
-
-
33747228489
-
Polymorphisms in the interleukin 6 and transforming growth factor beta1 gene and risk of dementia. The Rotterdam Study
-
van Oijen M, Arp PP, de Jong FJ, Hofman A, Koudstaal PJ, et al. (2006) Polymorphisms in the interleukin 6 and transforming growth factor beta1 gene and risk of dementia. The Rotterdam Study. Neurosci Lett. 402 (1-2): 113-7.
-
(2006)
Neurosci Lett
, vol.402
, Issue.1-2
, pp. 113-117
-
-
van Oijen, M.1
Arp, P.P.2
de Jong, F.J.3
Hofman, A.4
Koudstaal, P.J.5
-
31
-
-
0037120334
-
The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected]
-
Pola R, Flex A, Gaetani E, Lago AD, Gerardino L, et al. (2002) The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected]. Neuroreport. 13 (13): 1645-7.
-
(2002)
Neuroreport
, vol.13
, Issue.13
, pp. 1645-1647
-
-
Pola, R.1
Flex, A.2
Gaetani, E.3
Lago, A.D.4
Gerardino, L.5
-
32
-
-
0037042091
-
Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases
-
Shibata N, Ohnuma T, Takahashi T, Baba H, Ishizuka T, et al. (2002) Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases. Am J Med Genet. 2002; 114 (4): 436-9.
-
(2002)
Am J Med Genet. 2002
, vol.114
, Issue.4
, pp. 436-439
-
-
Shibata, N.1
Ohnuma, T.2
Takahashi, T.3
Baba, H.4
Ishizuka, T.5
-
33
-
-
72849147328
-
The combinations of TNFalpha-308 and IL-6-174 or IL-10-1082 genes polymorphisms suggest an association with susceptibility to sporadic late-onset Alzheimer's disease
-
Vural P, Deǧirmencioǧlu S, Parildar-Karpuzoǧlu H, Doǧru-Abbasoǧlu S, Hanagasi HA, et al. (2009) The combinations of TNFalpha-308 and IL-6-174 or IL-10-1082 genes polymorphisms suggest an association with susceptibility to sporadic late-onset Alzheimer's disease. Acta Neurol Scand. 120 (6): 396-401.
-
(2009)
Acta Neurol Scand
, vol.120
, Issue.6
, pp. 396-401
-
-
Vural, P.1
Deǧirmencioǧlu, S.2
Parildar-Karpuzoǧlu, H.3
Doǧru-Abbasoǧlu, S.4
Hanagasi, H.A.5
-
34
-
-
2942531060
-
Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease
-
Zhang Y, Hayes A, Pritchard A, Thaker U, Haque MS, et al. (2004) Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease. Neurosci Lett. 362 (2): 99-102.
-
(2004)
Neurosci Lett
, vol.362
, Issue.2
, pp. 99-102
-
-
Zhang, Y.1
Hayes, A.2
Pritchard, A.3
Thaker, U.4
Haque, M.S.5
-
35
-
-
78651237486
-
Interleukin-6 gene (-174 C/G) and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population
-
Klimkowicz-Mrowiec A, Wołkow P, Spisak K, Spisak K, Maruszak A, et al. (2010) Interleukin-6 gene (-174 C/G) and apolipoprotein E gene polymorphisms and the risk of Alzheimer disease in a Polish population. Neurol Neurochir Pol. 44 (6): 537-41.
-
(2010)
Neurol Neurochir Pol
, vol.44
, Issue.6
, pp. 537-541
-
-
Klimkowicz-Mrowiec, A.1
Wołkow, P.2
Spisak, K.3
Spisak, K.4
Maruszak, A.5
-
36
-
-
56649117352
-
Polymorphism 174 G/C of interleukin 6 gene in Alzheimer's disease-preliminary report
-
Paradowski B, Celczyńska D, Dobosz T, Noga L, (2008) Polymorphism 174 G/C of interleukin 6 gene in Alzheimer's disease-preliminary report. Neurol Neurochir Pol. 42 (4): 312-5.
-
(2008)
Neurol Neurochir Pol
, vol.42
, Issue.4
, pp. 312-315
-
-
Paradowski, B.1
Celczyńska, D.2
Dobosz, T.3
Noga, L.4
|