Interaction between dopamine β-hydroxylase and interleukin genes increases Alzheimer's disease risk [5]

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 77, Issue 2, 2006, Pages 278-279

  Mateo, I ^a   Infante, J ^a   Rodriguez E ^a   Berciano, J ^a   Combarros, Onofre ^a   Llorca, J ^b  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DOPAMINE; DOPAMINE BETA MONOOXYGENASE; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; NORADRENALIN;

AGED; ALLELE; ALZHEIMER DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; FEMALE; FISHER EXACT TEST; GENE EXPRESSION; GENE INTERACTION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CEREBRAL CORTEX; DOPAMINE; DOPAMINE BETA-HYDROXYLASE; EPISTASIS, GENETIC; FEMALE; GENOTYPE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MIDDLE AGED; NOREPINEPHRINE; POLYMORPHISM, GENETIC; RISK;

EID: 32344443997     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2005.075358     Document Type: Letter

References (5)

1. Healy DG, Abou-Sleiman PM, Ozawa T, et al. A functional polymorphism regulating dopamine β-hydroxylase influences against Parkinson's disease. Ann Neurol 2004;55:443-6.
2. Lyness SA, Zarow C, Chui HC. Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis. Neurobiol Aging 2003;24:1-23.
3. Heneka MT, Galea E, Gavriluyk V, et al. Noradrenergic depletion potentiates β-amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci 2002;22:2434-42.
4. Nicoll JAR, Mrak RE, Graham DI, et al. Association of interleukin-1 gene polymorphisms in Alzheimer's disease. Ann Neurol 2000;47:365-8.
5. Pola R, Flex A, Gaetani E, et al. The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population. Neuroreport 2002;13:1645-7.