Evaluation of the antihyperlipidemic, anti-inflammatory, analgesic, and antipyretic activities of ethanolic extract of Ammi majus seeds in albino rats and mice

International Journal of Toxicology

Volumn 31, Issue 3, 2012, Pages 294-300

  Koriem, Khaled M M ^a,b   Asaad, Gihan F ^b   Megahed, Hoda A ^b   Zahran, Hanan ^b   Arbid, Mahmoud S ^b  

^a ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Ammi majus; analgesic; anti inflammatory; anti pyretic; hyperlipidemia

Indexed keywords

ALCOHOL; AMMI MAJUS EXTRACT; CHOLESTEROL; FUROCOUMARIN DERIVATIVE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AMMI; AMMI MAJUS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; BODY TEMPERATURE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG ISOLATION; LIPOPROTEIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PAW EDEMA; PLANT SEED; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

AMMI; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIPYRETICS; CARRAGEENAN; DIET, HIGH-FAT; ETHANOL; FEVER; HOT TEMPERATURE; HYPERLIPIDEMIAS; HYPOLIPIDEMIC AGENTS; INFLAMMATION; MALE; MICE; PAIN; PHYTOTHERAPY; PLANT EXTRACTS; PSORALENS; RATS; RATS, SPRAGUE-DAWLEY; SACCHAROMYCES CEREVISIAE; SEEDS; SOLVENTS;

AMMI MAJUS; APIACEAE; MUS; RATTUS;

EID: 84862005469     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581812440889     Document Type: Article

References (38)

1. Central Council for Research in Unani Medicine. Standardisation of Single Drugs of Unani Medicine (Part I). New Delhi, India: Ministry of Health;1987:56-64.
2. Taeckholm V. Students Flora of Egypt. 1st ed. Egypt: Cairo University; 1960:99-105.
3. Ivie GW. Linear furocoumarins (psoralens) from the seed of Texas Ammi majus L. (Bishop's Weed). J Agric Food Chem. 1978;26(6):1394-1403.
4. Pokrovskii OI, Markoliya AA, Lepeshkin FD, Kuvykin IV, Parenago OO, Gonchukov SA. Extraction of linear furocoumarins from Ammi majus seeds by means of supercritical fluid extraction and supercritical fluid chromatography. Russ J Phys Chem B. 2009;3(8):1165-1171.
5. El Mofty AM. A preliminary clinical report on the treatment of leukodermia with Ammi majus Linn. J Egypt Med Assoc. 1948; 31(8):561-665.
6. Smith E. Constitution of Samidin, Dihydrosamidin and Visnadin. J Am Chem Soc. 1957;79(13):35-34.
7. Rosinov KS. Effects of furocoumarins on central nervous system II, correlations with anticonvulsants and central depressants. IZV. Inst Fiziol Bulg Akad Nauk. 1973;15:141-148.
8. Lilina DH, Kontogiorgis C, Pontiki E, Dakanali M, Akoumianaki A, Katerinopoulos HE. Anti-inflammatory and antioxidant activity of coumarins designed as potential flouresent zinc sensors. J Enzyme Inhib Med Chem. 2007;22(3):287-292. (Pubitemid 47225720)
9. Leal LK, Ferreira AA, Bezerra GA, Matos FJ, Viana GS. Anti-nociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. J Ethnopharmacol. 2000;70(2):151-159. (Pubitemid 30193241)
10. Ahmed R, Asaad M, Siddiqui Z, et al. Screening of synthetic new heterocyclic derivatives of 3-formyl-4 hydroxy coumarin for anti-inflammatory activity in albino rats. J Pharm Res Health Care. 2009:1:46-62.
11. Flakakidou KC, Hadjipavlou LDJ, Litinas KE, Nicolaides DN. Natural and synthetic coumarin derivatives with anti-inflammatory, antioxidant activities. Curr Pharm Des. 2004; 10(30):3818-3833.
12. Yuce B, Danis O, Ogan A, Sener G, Bulut M, Yarat A. Antioxidative and lipid lowering effects of 7,8 dihydroxy-3-(4-methyl phenyl) coumarin in hyperlipidemic rats. Arzneimittel Forsch. 2009;59(3):129-134.
13. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants (Including the Supplement). New Delhi, India: Council of Scientific and Industrial Research; 1986:402-405.
14. Shah AH, Qureshi S, Tariq M, Ageel AM. Toxicity studies on six plants used in the traditional Arab system of medicine. Phytother Res. 1989;3(1):25-29. (Pubitemid 19099255)
15. Farnsworth NR, ed. NAPRALERT Database. Chicago, IL: University of Illinois at Chicago; 2001:47-51.
16. Leung AY, Foster S. Encyclopedia of common natural ingredients used in food, drugs and cosmetics. New York, NY: John Wiley and Sons; 1996:84-92.
17. Wang H, Feng F, Zhuang BY, Sun Y. Evaluation of hepatoprotective effect of Zhi-Zi-Da-Huang decoction and its two fractions against acute alcohol-induced liver injury in rats. J Ethnopharmacol. 2009;126(2):273-279.
18. Ney DM, Laskan JB, Scinnich FL. Soluble oat fiber tends to normalize lipoprotein composition in cholesterol-fed rats. J Nutr. 1988;118(12):1455-1462. (Pubitemid 19042199)
19. Bucolo G, David H. Quantitative determination of serum triglycerides by the use of enzymes. J Clin Chem. 1973;19(5):476-482.
20. Allain CC, Poom LS. Enzymatic determination of total serum cholesterol. J Clin Chem. 1974;20(4):470-475.
21. Stein EA. Text Book of Clinical Chemistry. N. Wtietz, ed. Philadelphia, PA: W.B. Saunders; 1986:879-886.
22. Hamed MR, Hassanein NMA, Ali AA, EL-Nahhas TMY. An experimental study on the therapeutic efficacy of the combined administration of herbal medicines with atorvastatin against hyperlipidemia in rats. J Appl Sci Res. 2010;6(11):1730-1744.
23. Kothari S, Jain AK, Mehta SC, Tonpay SD. Hypolipidemic effect of fresh Triticum aestivum (wheat) grass juice in hypercholesterolimic rats. Acta Pol Pharm. 2011;68(2):291-294.
24. Winter CA, Risley EA, Nuss GW. Carrageenan induced edema in hind paws of the rat as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med. 1944;111:544-547.
25. Prempeh ABA, Mensah-Attipoe J. Inhibition of vascular response in inflammation by crude aqueous extract of the root bark of zanthoxylum xanthoxyloides. Ghana Med J. 2009; 43(2):77-81.
26. Woolfe CJ, Mc Donald AD. The evaluation of the analgesic action of pethidine hydrochloride (demerol). J Pharmacol Exp Ther. 1962;80(3):300-307.
27. Tayal V, Kalra BS, Chawla Sh. Evaluation of antidepressant activity of tramadol in mice. Indian J Pharmacol. 2008;40(3): 129-130.
28. Ashok BK, Ravishankar B, Prajapati PK, Bhat SD. Antipyretic activity of Guduchi Ghrita formulations in albino rats. Ayu. 2010; 31(3):367-70.
29. Manivel K, Rajangam P, Muthusamy K, Rajasekar S. Evaluation of anti-pyretic effect of Trichosanthes tricuspidata Linn on albino rats. Inter J Res Pharma Biomed Sci. 2011;2(4):1718-1720.
30. Howell P, Thomas C. Meta-analysis and scientific standards in efficacy research: a reply to Ingham and Bothe. J Fluency Disord. 2002;27(2):177-184. (Pubitemid 34563319)
31. Farnsworth NR, Fong HSH, Mahady GB. WHO Monographs on Selected Medicinal Plants. Vol. 3. Geneva, Switzerland: World Health Organization; 2007:9-22.
32. Abu-Mustafa EA, Fayez MBE. Natural coumarins. I. Marmesin and Marmesinin, further products from the fruits of Ammi majus L. J Org Chem. 1961;26(1):161-166.
33. Elgamal MHA, Shalaby NMM, Duddeck H, Hiegemann M. Coumarins and coumarins glycosides from the fruits of Ammi majus. Phytochem. 1993;34(3):819-823. (Pubitemid 2006012)
34. Sashidhara KV, Kumar A, Kumar M, Srivastava A, Puri A. Synthesis and antihyperlipidemic activity of novel coumarin bisindole derivatives. Bioorg Med Chem Lett. 2010;20(22):6504-6507.
35. Vinegar R, Scheirber W, Hugo R. Biphasic development of carageenin edema in rat. J Pharmacol Exp Ther. 1969;166(1): 96-103.
36. Hoult JR, Forder RA, Heras B, Lobo IB, Payá M. Inhibitory activity of a series of coumarins on leukocyte eicosanoid generation. Agents Actions. 1994;42(1-2):44-49.
37. Li SH, Chu Y. Anti-inflammatory effects of total coumarins of Panax notoginseng. Zhongguo Yao Li Xue Bao. 1999;20(6): 551-554. (Pubitemid 29302421)
38. Tomazetti J, Avila DS, Ferreira AP, et al. Baker yeast-induced fever in young rats: characterization and validation of an animal model for antipyretics screening. J Neurosci Meth. 2005;147(1): 29-35. (Pubitemid 41058666)