Evaluation of antidepressant activity of tramadol in mice

Indian Journal of Pharmacology

Volumn 40, Issue 3, 2008, Pages 129-130

  Tayal, Vandana ^a   Kalra, Bhupinder ^b   Chawla, Shalini ^a  

^a MAULANA AZAD MEDICAL COLLEGE   (India)

^b ITS Dental College   (India)

Author keywords

Antidepressant; Tail suspension test; Tramadol

Indexed keywords

FLUOXETINE; TRAMADOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; EXPERIMENTAL TEST; FEMALE; IMMOBILIZATION; MALE; MOUSE; NONHUMAN; TAIL; TAIL SUSPENSION TEST;

EID: 49449099011     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.42307     Document Type: Article

References (13)

1. Rojas-Corrales MO, Gibert-Rahola J, Mico JA. Tramadol induces antidepressant-type effects in mice. Life Sci 1998;63:175-80.
2. Desmeules JA, Piguet V, Collart L, Dayer P. Contribution of monoaminergic modulation to the analgesic effect of tramadol. Br J Clin Pharmacol 1996;41:7-12.
3. Driessen B, Reimann W, Giertz H. Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro. Br J Pharmacol 1993;108:806-11.
4. Sevcik J, Nieber K, Driessen B, Illes P. Effects of the central analgesic tramadol and its main metabolite, O-desmethyltramadol, on rat locus coeruleus neurones. Br J Pharmacol 1993;110:169-76.
5. Kiayias JA, Vlacchou ED, Lakka PE. Venlafaxime HCl in the treatment of painful peripheral diabetic neuropathy. Diabetes Care 2000;23:699.
6. Rojas-Corrales MO, Berrocoso E, Gibert-Rahola J, Mico JA. Antidepressant-like effects of tramadol and other central analgesics with activity on monoamines reuptake, in helpless rats. Life Sci 2002;72:143-52.
7. Spencer C. The efficacy of intramuscular tramadol as a rapid-onset antidepressant. Aust N Z J Psychiatry 2000;34:1032-3.
8. Shapira NA, Verduin ML, Degraw JD. Treatment of refractory major depression with tramadol hydrochloride monotherapy. J Clin Psych 2001;62:205-6.
9. Vogel GH, Vogel WH. Drug discovery and evaluation-pharmacological assays. Spinger Publication; 1997. p. 292-312.
10. Steru L, Chermat R, Thierry B, Simon P. The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacol 1985;85:367-70.
11. Rodrigues AS, da Silva GL, Mateussi AS, Fernandes ES, Miguel OG, Yunes RA, et al. Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life Sci 2002;70:1347-58.
12. Dhingra D, Sharma A. Evaluation of antidepressant-like activity of glycyrrhizin in mice. Indian J Pharmacol 2005;6:390-4.
13. Jha PK, Mazumdar B, Bhatt JD. Analgesic activity of venlafaxine and its interactions with tramadol, celecoxib and amlodipine in mice. Indian J Pharmacol 2006;38:181-4.