Mutations in Streptococcus pneumoniae penicillin-binding protein 2x: Importance of the C-terminal penicillin-binding protein and serine/threonine kinase-associated domains for beta-lactam binding

Microbial Drug Resistance

Volumn 18, Issue 3, 2012, Pages 314-321

  Maurer, Patrick ^a   Todorova, Katya ^a   Sauerbier, Julia ^a   Hakenbeck, Regine ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BOCILLIN FL; CEFOTAXIME; CEFUROXIME; PENICILLIN BINDING PROTEIN 2X; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM MUTANT; CARBOXY TERMINAL SEQUENCE; COMPUTER MODEL; CONTROLLED STUDY; COVALENT BOND; DRUG BINDING; ENZYME ACTIVE SITE; GENE DELETION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; STREPTOCOCCUS PNEUMONIAE; X RAY CRYSTALLOGRAPHY;

ANTI-BACTERIAL AGENTS; BINDING SITES; BORON COMPOUNDS; CEFOTAXIME; CEFUROXIME; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, MICROBIAL; MODELS, MOLECULAR; PENICILLIN-BINDING PROTEINS; PENICILLINS; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SERINE; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

STREPTOCOCCUS PNEUMONIAE;

EID: 84862002474     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2012.0022     Document Type: Article

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