Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae

FEBS Letters

Volumn 585, Issue 2, 2011, Pages 357-363

  Maestro, Beatriz ^a   Novaková, Linda ^b   Hesek, Dusan ^c   Lee, Mijoon ^c   Leyva, Eduardo ^a   Mobashery, Shahriar ^c   Sanz, Jesús M ^a   Branny, Pavel ^b  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Lactam antibiotics; Penicillin binding protein and Ser Thr protein kinase associated domain; Peptidoglycan; Protein structure; Signal transduction; Streptococcus pneumoniae

Indexed keywords

6 AMINOPENICILLANIC ACID; AMPICILLIN; PEPTIDOGLYCAN; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME STABILITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; BINDING SITES; CELL WALL; MODELS, MOLECULAR; PEPTIDOGLYCAN; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN-SERINE-THREONINE KINASES; SPECTRUM ANALYSIS; STREPTOCOCCUS PNEUMONIAE;

EUKARYOTA; STREPTOCOCCUS PNEUMONIAE;

EID: 78651376345     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.12.016     Document Type: Article

References (28)

1. J.A. Hoch Two-component and phosphorelay signal transduction Curr. Opin. Microbiol. 3 2000 165 170
2. A.M. Stock, V.L. Robinson, and P.N. Goudreau Two-component signal transduction Annu. Rev. Biochem. 69 2000 183 215
3. G. Jones, and P. Dyson Evolution of transmembrane protein kinases implicated in coordinating remodeling of Gram-positive peptidoglycan: inside versus outside J. Bacteriol. 188 2006 7470 7476 (Pubitemid 44646246)
4. A. Krupa, and N. Srinivasan Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes BMC Genom. 6 2005 129 (Pubitemid 41372411)
5. Y. Av-Gay, S. Jamil, and S.J. Drews Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB Infect. Immun. 67 1999 5676 5682 (Pubitemid 29508085)
6. C. Yeats, R.D. Finn, and A. Bateman The PASTA domain: a β-lactam-binding domain Trends Biochem. Sci. 27 2002 438 440
7. S. Pares, N. Mouz, Y. Pétillot, R. Hakenbeck, and O. Dideberg X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme Nat. Struct. Biol. 3 1996 284 289 (Pubitemid 26081712)
8. P. Barthe, G.V. Mukamolova, R. Roumestand, and M. Cohen-Gonsaud The structure of PknB extracellular PASTA domain from Mycobacterium tuberculosis suggests a ligand-dependent kinase activation Structure 18 2010 606 615
9. E. Gordon, N. Mouz, E. Duée, and O. Dideberg The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance J. Mol. Biol. 299 2000 477 485
10. D.J. Tipper, and J.L. Strominger Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-d-alanyl-d-alanine Proc. Natl. Acad. Sci. USA 54 1965 1133 1141
11. I.M. Shah, M.-H. Laaberki, D.L. Popham, and J. Dworkin A eukaryotic-like Ser/Thr kinase signals bacteria to exit dormancy in response to peptidoglycan fragments Cell 135 2008 486 496
12. P. Pallová, K. Hercik, L. Sasková, L. Nová ková, and P. Branny A eukaryotic-type serine/threonine protein kinase StkP of Streptococcus pneumoniae acts as a dimer in vivo Biochem. Biophys. Res. Commun. 355 2007 526 530 (Pubitemid 46282660)
13. L. Sasková, L. Nováková, M. Basler, and P. Branny Eukaryotic-type serine/threonine protein kinase StkP is a global regulator of gene expression in Streptococcus pneumoniae J. Bacteriol. 189 2007 4168 4179 (Pubitemid 46847365)
14. L. Nováková, L. Sasková, P. Pallová, J. Janeček, J. Novotná, A. Ulrych, J. Echenique, M.-C. Trombe, and P. Branny Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates FEBS J. 272 2005 1243 1254 (Pubitemid 40314942)
15. D. Hesek, M. Lee, K.-I. Morio, and S. Mobashery Synthesis of a fragment of bacterial cell wall J. Org. Chem. 69 2004 2137 2146 (Pubitemid 38366680)
16. D. Hesek, M. Suvorov, K.-I. Morio, M. Lee, S. Brown, S.B. Vakulenko, and S. Mobashery Synthetic peptidoglycan substrates for penicillin-binding protein 5 (PBP5) of Gram-negative bacteria J. Org. Chem. 69 2004 778 784 (Pubitemid 38168545)
17. N. Guex, and M.C. Peitsch SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling Electrophoresis 18 1997 2714 2723 (Pubitemid 28059943)
18. J. Sambrook, E.F. Fritsch, and T. Maniatis Molecular Cloning: A Laboratory Manual second ed. 1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
19. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
20. Fasman, G.D. (1976), Handbook of Biochemistry and Molecular biology. Section A: Proteins, vol. III, third ed, CRC Press Inc., Cleveland, OH.
21. G. Bohm, R. Muhr, and R. Jaenicke Quantitative analysis of protein far UV circular dichroism spectra by neural networks Protein Eng. 5 1992 191 195
22. R.F. Greene Jr., and C.N. Pace Urea and guanidinium chloride denaturation of ribonuclease, lysozyme, α-chymotrypsin, and β-lactoglobulin J. Biol. Chem. 249 1974 5388 5393
23. D.A. Morrison, S.A. Lacks, W.R. Guild, and J.M. Hageman Isolation and characterization of three new classes of transformation-deficient mutants of Streptococcus pneumoniae that are defective in DNA transport and genetic recombination J. Bacteriol. 156 1983 281 290
24. T.E. Creighton Proteins: Structures and Molecular Properties second ed. 1993 W.H. Freeman and Co. USA
25. W.C. Johnson Protein secondary structure and circular dichroism: a practical guide Proteins Struct. Funct. Genet. 7 1990 205 214
26. J.F. García-Bustos, B.T. Chait, and A. Tomasz Structure of the peptide network of pneumococcal peptidoglycan J. Biol. Chem. 262 1987 15400 15405
27. W.W. Navarre, H. Ton-That, K.F. Faull, and O. Schneewind Multiple enzymatic activities of the murein hydrolase from staphylococcal phage φ11. Identification of a d-alanyl-glycine endopeptidase activity J. Biol. Chem. 274 1999 15847 15856 (Pubitemid 129518947)
28. A. Velasco, S. Alonso, J.L. García, J. Perera, and E. Díaz Genetic and functional analysis of the styrene catabolic cluster of Pseudomonas sp. strain Y2 J. Bacteriol. 180 1998 1063 1071 (Pubitemid 28119462)