Epithelial to mesenchymal transition is activated in metastatic pheochromocytomas and paragangliomas caused by SDHB gene mutations

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 6, 2012, Pages

  Loriot, Céline ^a,d   Burnichon, Nelly ^a,b,d   Gadessaud, Noémie ^a   Vescovo, Laure ^e   Amar, Laurence ^a,c,d   Libé, Rossella ^d,f,g,h   Bertherat, Jérôme ^d,f,g,h   Plouin, Pierre François ^a,c,d,h   Jeunemaitre, Xavier ^a,b,d   Gimenez Roqueplo, Anne Paule ^a,b,d,h   Favier, Judith ^a,d  

^a INSERM   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c Service d'Hypertension Artérielle   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e Cartes d'Identité des Tumeurs Program   (France)

^f CNRS   (France)

^g Centre de Référence Maladies Rares de la Surrénale ^*  (France)

^h INSTITUT NATIONAL DU CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; INTERSTITIAL COLLAGENASE; METALLOPROTEINASE; TRANSCRIPTION FACTOR 7 LIKE 1; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; TRANSCRIPTION FACTOR SNAIL2; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER PATIENT; CDH2 GENE; CELL ACTIVATION; CELL INVASION; CELL JUNCTION; CELL MOTILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE TRANSLOCATION; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KRT19 GENE; LOXL2 GENE; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; MMP1 GENE; MMP2 GENE; ONCOGENE; PARAGANGLIOMA; PHENOTYPE; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; SDHB GENE; TCF3 GENE; TRANSCRIPTOMICS; TWIST GENE;

ADRENAL GLAND NEOPLASMS; AMINO ACID OXIDOREDUCTASES; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL COMMUNICATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERCELLULAR JUNCTIONS; MUTATION; NUCLEAR PROTEINS; PARAGANGLIOMA; PHEOCHROMOCYTOMA; PROGNOSIS; RISK FACTORS; SIGNAL TRANSDUCTION; SUCCINATE DEHYDROGENASE; TRANSCRIPTION FACTORS; TRANSCRIPTOME; TWIST TRANSCRIPTION FACTOR;

EID: 84861996762     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-3437     Document Type: Article

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