Salacia oblonga ameliorates hypertriglyceridemia and excessive ectopic fat accumulation in laying hens

Journal of Ethnopharmacology

Volumn 142, Issue 1, 2012, Pages 221-227

  Wang, Jianwei ^a   Rong, Xianglu ^b   Li, Wenlong ^c   Yamahara, Johji ^d   Li, Yuhao ^e,f  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^c UNIVERSITY OF SYDNEY   (Australia)

^d Pharmafood Institute   (Japan)

^e UNIVERSITY OF SYDNEY   (Australia)

^f Sydney Institute of Health Sciences   (Australia)

Author keywords

Ectopic; Hen; Salacia oblonga; Triglyceride

Indexed keywords

GLUCOSE; PLANT EXTRACT; SALACIA OBLONGA EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEART; HEN; HYPERTRIGLYCERIDEMIA; LIPID METABOLISM; LIVER; NONHUMAN; PLANT ROOT; PLASMA; PULLET; SALACIA; SALACIA OBLONGA; SKELETAL MUSCLE;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; CHICKENS; FEMALE; HEART; HYPERTRIGLYCERIDEMIA; LIPID METABOLISM; LIVER; MUSCLE, SKELETAL; MYOCARDIUM; ORGAN SIZE; PLANT EXTRACTS; PLANT ROOTS; SALACIA;

ANIMALIA; SALACIA OBLONGA;

EID: 84861985682     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.04.048     Document Type: Article

References (29)

1. Chandrasena, J.P.C., 1935. The Chemistry and Pharmacology of Ceylon and Indian Medicinal Plants. H&C Press, Colombo, Sri Lanka.
2. Dashti, N., Kelley, J.L., Thayer, R.H., Ontko, J.A., 1983. Concurrent inductions of avian hepatic lipogenesis, plasma lipids, and plasma apolipoprotein B by estrogen. Journal of Lipid Research 24, 368-380.
3. Fabbrini, E., Sullivan, S., Klein, S., 2010. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 51, 679-689.
4. Feige, J.N., Gelman, L., Michalik, L., Desvergne, B., Wahli, W., 2006. From molecular action to physiological outputs: peroxisome proliferator- activated receptors are nuclear receptors at the crossroads of key cellular functions. Progress in Lipid Research 45, 120-159.
5. Flammang, A.M., Erexson, G.L., Mirwald, J.M., Henwood, S.M., 2007. Toxicological and cytogenetic assessment of a Salacia oblonga extract in a rat subchronic study. Food and Chemical Toxicology 45, 1954-1962.
6. Francis, G.A., Annicotte, J.S., Auwerx, J., 2003. PPAR-alpha effects on the heart and other vascular tissues. American Journal of Physiology-Heart and Circulatory Physiology 285, H1-H9.
7. Girón, M.D., Sevillano, N., Salto, R., Haidour, A., Manzano, M., Jiménez, M.L., Rueda, R., López-Pedrosa, J.M., 2009. Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: role of mangiferin. Clinical Nutrition 28, 565-574.
8. He, L., Qi, Y., Jiang, J., Yang, Q., Yamahara, J., Murray, M., Li, Y., 2011. The Ayurvedic medicine Salacia oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling. Evidence-Based Complementary and Alternative Medicine 2011, 807451.
9. Hermier, D., Forgez, P., Williams, J., Chapman, M.J., 1989. Alterations in plasma lipoproteins and apolipoproteins associated with estrogen-induced hyperlipidemia in the laying hen. European Journal of Biochemistry 184, 109-118.
10. Huang, T.H., Peng, G., Li, G.Q., Yamahara, J., Roufogalis, B.D., Li, Y., 2006a. Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in Zucker diabetic fatty rats: activation of PPAR-alpha. Toxicology and Applied Pharmacology 210, 225-235.
11. Huang, T.H.W., Yang, Q., Harada, M., Uberai, J., Radford, J., Li, G.Q., Yamahara, J., Roufogalis, B.D., Li, Y., 2006b. Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats: modulation of cardiac PPAR-α-mediated transcription of fatty acid metabolic genes. Toxicology and Applied Pharmacology 210, 78-85.
12. Huang, T.H.W., He, L., Qin, Q., Yang, Q., Peng, G., Harada, M., Qi, Y., Yamahara, J., Roufogalis, B.D., Li, Y., 2008. Salacia oblonga decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor. Diabetes, Obesity and Metabolism 10, 574-585.
13. Hwang, J.H., Stein, D.T., Barzilai, N., Cui, M.H., Tonelli, J., Kishore, P., Hawkins, M., 2007. Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies. American Journal of Physiology-Endocrinology and Metabolism 293, E1663-E1669.
14. König, B., Kluge, H., Haase, K., Brandsch, C., Stangl, G.I., Eder, K., 2007. Effects of clofibrate treatment in laying hens. Poultry Science 86, 1187-1195.
15. K̈onig, B., Spielmann, J., Haase, K., Brandsch, C., Kluge, H., Stangl, G.I., Eder, K., 2008. Effects of fish oil and conjugated linoleic acids on expression of target genes of PPAR alpha and sterol regulatory element-binding proteins in the liver of laying hens. British Journal of Nutrition 100, 355-363.
16. Kudzma St, D.J., Claire, F., DeLallo, L., Friedberg, S.J., 1975. Mechanism of avian estrogen-induced hypertriglyceridemia: evidence for overproduction of triglyceride. Journal of Lipid Research 16, 123-133.
17. Landers, K.L., Moore, R.W., Herrera, P., Landers, D.A., Howard, Z.R., McReynolds, J.L., Bryd, J.A., Kubena, L.F., Nisbet, D.J., Ricke, S.C., 2008. Organ weight and serum triglyceride responses of older (80 week) commercial laying hens fed an alfalfa meal molt diet. Bioresource Technology 99, 6692-6696.
18. Lettner, A., Roden, M., 2008. Ectopic fat and insulin resistance. Current Diabetes Reports 8, 185-191.
19. Li, Y., Peng, G., Li, Q., Wen, S., Huang, T.H., Roufogalis, B.D., Yamahara, J., 2004. Salacia oblonga improves cardiac fibrosis and inhibits postprandial hyperglycemia in obese Zucker rats. Life Sciences 75, 1735-1746.
20. Li, Y., Huang, T.H., Yamahara, J., 2008. Salacia root, a unique ayurvedic medicine, meets multiple targets in diabetes and obesity. Life Sciences 82, 1045-1049.
21. Loomba, R., Sirlin, C.B., Schwimmer, J.B., Lavine, J.E., 2009. Advances in pediatric nonalcoholic fatty liver disease. Hepatology 50, 1282-1293.
22. Postic, C., Girard, J., 2008. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. Journal of Clinical Investigation 118, 829-838.
23. Rong, X., Kim, M.S., Su, N., Wen, S., Matsuo, Y., Yamahara, J., Murray, M., Li, Y., 2008. An aqueous extract of Salacia oblonga root, a herb-derived peroxisome proliferator-activated receptor-alpha activator, by oral gavage over 28 days induces gender-dependent hepatic hypertrophy in rats. Food and Chemical Toxicology 46, 2165-2172.
24. Rong, X., Li, Y., Ebihara, K., Zhao, M., Aini, W., Kusakabe, T., Hirata, M., Miyamoto, L., Murray, M., Nakao, K., 2009. An adipose tissue-independent insulin-sensitizing action of telmisartan: a study in lipodystrophic mice. Journal of Pharmacology and Experimental Therapeutics 331, 1096-1103.
25. k) rats: a link to amelioration of hypertriglyceridaemia. British Journal of Pharmacology 160, 1796-1807.
26. Rong, X., Li, Y., Ebihara, K., Zhao, M., Naowaboot, J., Kusakabe, T., Kuwahara, K., Murray, M., Nakao, K., 2010b. Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice. Diabetologia 53, 1727-1731.
27. Shimada, T., Nagai, E., Harasawa, Y., Watanabe, M., Negishi, K., Akase, T., Sai, Y., Miyamoto, K., Aburada, M., 2011. Salacia reticulata inhibits differentiation of 3T3-L1 adipocytes. Journal of Ethnopharmacology 136, 67-74.
28. Walzem, R.L., Hansen, R.J., Williams, D.L., Hamilton, R.L., 1999. Estrogen induction of VLDLy assembly in egg-laying hens. Journal of Nutrition 129 (Suppl. 2S), 467S-472S.
29. Yoshikawa, M., Nishida, N., Shimoda, H., Takada, M., Kawahara, Y., Matsuda, H., 2001. Polyphenol constituents from Salacia species: quantitative analysis of mangiferin with alpha-glucosidase and aldose reductase inhibitory activities. Yakugaku Zasshi 121, 371-378.