An aqueous extract of Salacia oblonga root, a herb-derived peroxisome proliferator-activated receptor-alpha activator, by oral gavage over 28 days induces gender-dependent hepatic hypertrophy in rats

Food and Chemical Toxicology

Volumn 46, Issue 6, 2008, Pages 2165-2172

  Rong, Xianglu ^a   Kim, Moon Sun ^b   Su, Ning ^a   Wen, Suping ^c   Matsuo, Yukimi ^d   Yamahara, Johji ^e   Murray, Michael ^b   Li, Yuhao ^b  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^d Koei Kogyo Co   (Japan)

^e Pharmafood Institute   (Japan)

Author keywords

Gender; Hypertrophy; Liver; PPAR ; Rat; Salacia oblonga

Indexed keywords

ACYL COENZYME A OXIDASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PLANT EXTRACT; SALACIA OBLONGA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; LIPID STORAGE; LIVER HYPERTROPHY; MALE; NONHUMAN; PEROXISOME; PLANT ROOT; PROTEIN EXPRESSION; RAT; SEX DIFFERENCE; UPREGULATION;

ACYL COENZYME A; ANIMALS; BODY WEIGHT; CELL LINE, TUMOR; DATA INTERPRETATION, STATISTICAL; FATTY LIVER; FEMALE; GENE EXPRESSION; HUMANS; HYPERTROPHY; LIVER; LIVER NEOPLASMS; MALE; PLANT EXTRACTS; PLANT ROOTS; PPAR ALPHA; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SALACIA; SEX CHARACTERISTICS; WEIGHT GAIN;

RATTUS; SALACIA OBLONGA;

EID: 42749089152     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.02.022     Document Type: Article

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