Structural basis for polyadenosine-RNA binding by Nab2 Zn fingers and its function in mRNA nuclear export

Structure

Volumn 20, Issue 6, 2012, Pages 1007-1018

  Brockmann, Christoph ^a,d   Soucek, Sharon ^b   Kuhlmann, Sonja I ^a   Mills Lujan, Katherine ^b   Kelly, Seth M ^b   Yang, Ji Chun ^a   Iglesias, Nahid ^c,e   Stutz, Francoise ^c   Corbett, Anita H ^b   Neuhaus, David ^a   Stewart, Murray ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Sciences III ^*  (Switzerland)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MESSENGER RNA; NUCLEAR RNA; POLYADENOSINE RNA BINDING PROTEIN NAB2; RNA HELICASE; RNA HELICASE DBP5; UNCLASSIFIED DRUG;

ADENYLATION; ALLELE; ARTICLE; CYTOPLASM; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RNA BINDING; ZINC FINGER MOTIF;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CONSERVED SEQUENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; POLYMERS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA TRANSPORT; RNA, MESSENGER; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SURFACE PROPERTIES; THERMODYNAMICS; ZINC FINGERS;

EID: 84861978013     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.03.011     Document Type: Article

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