메뉴 건너뛰기




Volumn 4, Issue 1, 2012, Pages 48-57

An advanced stochastic model for mucociliary particle clearance in cystic fibrosis lungs

Author keywords

24 h retention; Clearance model; Mucociliary clearance; Stochastic lung structure

Indexed keywords


EID: 84861972279     PISSN: 20721439     EISSN: 20776624     Source Type: Journal    
DOI: 10.3978/j.issn.2072-1439.2011.09.09     Document Type: Article
Times cited : (12)

References (34)
  • 1
    • 0037027912 scopus 로고    scopus 로고
    • An overview of the pathogenesis of cystic fibrosis lung disease
    • Boucher RC. An overview of the pathogenesis of cystic fibrosis lung disease. Adv Drug Deliv Rev 2002;54:1359-71.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1359-1371
    • Boucher, R.C.1
  • 2
    • 0027935540 scopus 로고
    • Genotype defect: Its effect on cellular function and phenotypic expression
    • Cutting GR. Genotype defect: Its effect on cellular function and phenotypic expression. Sem Respir Crit Care Med 1994;15:356-63.
    • (1994) Sem Respir Crit Care Med , vol.15 , pp. 356-363
    • Cutting, G.R.1
  • 3
    • 0000026508 scopus 로고
    • Cystic Fibrosis
    • Scriver CR, Beaudet AL, Sly WS, Valle D, Stanbury JB, Wyngaarden JB, Fredrickson DS, editors. New York: McGraw-Hill
    • Welsh MJ, Tsui TF, Boat LC, Beaudet AL. Cystic Fibrosis. In: Scriver CR, Beaudet AL, Sly WS, Valle D, Stanbury JB, Wyngaarden JB, Fredrickson DS, editors. Cystic Fibrosis., Vol. 7. New York: McGraw-Hill 1995. p .3799-876.
    • (1995) Cystic Fibrosis , vol.7 , pp. 3799-3876
    • Welsh, M.J.1    Tsui, T.F.2    Boat, L.C.3    Beaudet, A.L.4
  • 6
    • 0028920643 scopus 로고
    • Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface
    • Imundo L, Barasch J, Prince A, Al-Awqati Q. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface. Proc Natl Acad Sci U S A 1995;92:3019-23.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3019-3023
    • Imundo, L.1    Barasch, J.2    Prince, A.3    Al-Awqati, Q.4
  • 7
    • 0029870085 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
    • Smith JJ, Travis SM, Greenberg EP, Welsh MJ. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 1996;85:229-36.
    • (1996) Cell , vol.85 , pp. 229-236
    • Smith, J.J.1    Travis, S.M.2    Greenberg, E.P.3    Welsh, M.J.4
  • 8
    • 0035178729 scopus 로고    scopus 로고
    • Altered NaCl concentration of airway surface liquid in cystic fibrosis
    • Widdicombe JH. Altered NaCl concentration of airway surface liquid in cystic fibrosis. Pflugers Arch 2001;443 Suppl 1:S8-10.
    • (2001) Pflugers Arch , vol.443 , Issue.SUPPL. 1
    • Widdicombe, J.H.1
  • 9
    • 0033560645 scopus 로고    scopus 로고
    • Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model
    • Bals R, Weiner DJ, Meegalla RL, Wilson JM. Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. J Clin Invest 1999;103:1113-7.
    • (1999) J Clin Invest , vol.103 , pp. 1113-1117
    • Bals, R.1    Weiner, D.J.2    Meegalla, R.L.3    Wilson, J.M.4
  • 10
    • 0032433707 scopus 로고    scopus 로고
    • Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
    • Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, et al. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 1998;95:1005-15.
    • (1998) Cell , vol.95 , pp. 1005-1015
    • Matsui, H.1    Grubb, B.R.2    Tarran, R.3    Randell, S.H.4    Gatzy, J.T.5    Davis, C.W.6
  • 11
    • 0036167851 scopus 로고    scopus 로고
    • Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
    • Worlitzsch D, Tarran R, Ulrich M, Schwab U, Cekici A, Meyer KC, et al. Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest 2002;109:317-25.
    • (2002) J Clin Invest , vol.109 , pp. 317-325
    • Worlitzsch, D.1    Tarran, R.2    Ulrich, M.3    Schwab, U.4    Cekici, A.5    Meyer, K.C.6
  • 13
    • 0019193041 scopus 로고
    • Deposition, retention, and clearance of inhaled particles
    • Lippmann M, Yeates DB, Albert RE. Deposition, retention, and clearance of inhaled particles Br J Ind Med 1980;37:337-62.
    • (1980) Br J Ind Med , vol.37 , pp. 337-362
    • Lippmann, M.1    Yeates, D.B.2    Albert, R.E.3
  • 14
    • 0014516727 scopus 로고
    • The characteristics of bronchial clearance in humans and the effects of cigarette smoking
    • Albert RE, Lippmann M, Briscoe W. The characteristics of bronchial clearance in humans and the effects of cigarette smoking. Arch Environ Health 1969;18:738-55.
    • (1969) Arch Environ Health , vol.18 , pp. 738-755
    • Albert, R.E.1    Lippmann, M.2    Briscoe, W.3
  • 15
    • 0034885192 scopus 로고    scopus 로고
    • The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition
    • Tarran R, Grubb BR, Gatzy JT, Davis CW, Boucher RC. The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition. J Gen Physiol 2001;118:223-36.
    • (2001) J Gen Physiol , vol.118 , pp. 223-236
    • Tarran, R.1    Grubb, B.R.2    Gatzy, J.T.3    Davis, C.W.4    Boucher, R.C.5
  • 16
    • 0036194724 scopus 로고    scopus 로고
    • Mucus clearance as a primary innate defense mechanism for mammalian airways
    • Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 2002;109:571-7.
    • (2002) J Clin Invest , vol.109 , pp. 571-577
    • Knowles, M.R.1    Boucher, R.C.2
  • 17
    • 0018654284 scopus 로고
    • A model for tracheobronchial clearance of inhaled particles in man and a comparison with data
    • Lee PS, Gerrity TR, Hass FJ, Lourenco RV. A model for tracheobronchial clearance of inhaled particles in man and a comparison with data. IEEE Trans Biomed Eng 1979;26:624-30.
    • (1979) IEEE Trans Biomed Eng , vol.26 , pp. 624-630
    • Lee, P.S.1    Gerrity, T.R.2    Hass, F.J.3    Lourenco, R.V.4
  • 19
    • 0035042542 scopus 로고    scopus 로고
    • Mucociliary clearance of insoluble particles from the tracheobronchial airways of the human lung
    • Asgharian B, Hofmann W, Miller FJ. Mucociliary clearance of insoluble particles from the tracheobronchial airways of the human lung. J Aerosol Sci 2001;32:817-32.
    • (2001) J Aerosol Sci , vol.32 , pp. 817-832
    • Asgharian, B.1    Hofmann, W.2    Miller, F.J.3
  • 20
    • 33846471896 scopus 로고    scopus 로고
    • Stochastic modeling predictions for the clearance of insoluble particles from the tracheobronchial tree of the human lung
    • Sturm R, Hofmann W. Stochastic modeling predictions for the clearance of insoluble particles from the tracheobronchial tree of the human lung. Bull Math Biol 2007;69:395-415.
    • (2007) Bull Math Biol , vol.69 , pp. 395-415
    • Sturm, R.1    Hofmann, W.2
  • 21
    • 1942533004 scopus 로고    scopus 로고
    • Stochastic model of particle clearance in human bronchial airways
    • Hofmann W, Sturm R. Stochastic model of particle clearance in human bronchial airways. J Aerosol Med 2004;17:73-89.
    • (2004) J Aerosol Med , vol.17 , pp. 73-89
    • Hofmann, W.1    Sturm, R.2
  • 22
    • 0003438426 scopus 로고
    • International Commission on Radiological Protection (ICRP). Publication 66. Oxford: Pergamon Press
    • International Commission on Radiological Protection (ICRP). Human respiratory tract model for radiological protection. Publication 66. Oxford: Pergamon Press;1994.478 p.
    • (1994) Human respiratory tract model for radiological protection , pp. 478
  • 23
    • 0141744976 scopus 로고    scopus 로고
    • Mechanistic interpretation of the slow bronchial clearance phase
    • Sturm R, Hofmann W. Mechanistic interpretation of the slow bronchial clearance phase. Radiat Prot Dosimetry 2003;105:101-4.
    • (2003) Radiat Prot Dosimetry , vol.105 , pp. 101-104
    • Sturm, R.1    Hofmann, W.2
  • 24
    • 0018728405 scopus 로고
    • Anatomic models of the tracheobronchial and pulmonary regions of the rat
    • Yeh HC, Schum GM, Duggan MT. Anatomic models of the tracheobronchial and pulmonary regions of the rat. Anat Rec 1979;195:483-92.
    • (1979) Anat Rec , vol.195 , pp. 483-492
    • Yeh, H.C.1    Schum, G.M.2    Duggan, M.T.3
  • 25
    • 0025587183 scopus 로고
    • Monte Carlo modeling of aerosol deposition in human lungs. Part I: Simulation of particle transport in a stochastic lung structure
    • Koblinger L, Hofmann W. Monte Carlo modeling of aerosol deposition in human lungs. Part I: Simulation of particle transport in a stochastic lung structure. J Aerosol Sci 1990; 21:661-74.
    • (1990) J Aerosol Sci , vol.21 , pp. 661-674
    • Koblinger, L.1    Hofmann, W.2
  • 27
    • 0019997008 scopus 로고
    • Resistance of mucus-lined tubes to steady and oscillatory airflow
    • King M, Chang HK, Weber ME. Resistance of mucus-lined tubes to steady and oscillatory airflow. J Appl Physiol 1982;52:1172-6.
    • (1982) J Appl Physiol , vol.52 , pp. 1172-1176
    • King, M.1    Chang, H.K.2    Weber, M.E.3
  • 28
    • 0036841884 scopus 로고    scopus 로고
    • Ultrafine particle deposition and clearance in the healthy and obstructed lung
    • Brown JS, Zeman KL, Bennett WD. Ultrafine particle deposition and clearance in the healthy and obstructed lung. Am J Respir Crit Care Med 2002;166:1240-7.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1240-1247
    • Brown, J.S.1    Zeman, K.L.2    Bennett, W.D.3
  • 30
    • 0028907783 scopus 로고
    • Lung particle overload: implications for occupational exposures to particles
    • Oberdörster G. Lung particle overload: implications for occupational exposures to particles Regul Toxicol Pharmacol 1995;21:123-35.
    • (1995) Regul Toxicol Pharmacol , vol.21 , pp. 123-135
    • Oberdörster, G.1
  • 31
    • 84970647170 scopus 로고
    • Review: The 'particle overload' phenomenon and human risk assessment
    • Levy LS. Review: The 'particle overload' phenomenon and human risk assessment. Indoor Built Env 1995;4:254-62.
    • (1995) Indoor Built Env , vol.4 , pp. 254-262
    • Levy, L.S.1
  • 32
    • 34047154428 scopus 로고    scopus 로고
    • Mucolytics in cystic fibrosis
    • Henke MO, Ratjen F. Mucolytics in cystic fibrosis. Ped Resp Rev 2007;8:24-9.
    • (2007) Ped Resp Rev , vol.8 , pp. 24-29
    • Henke, M.O.1    Ratjen, F.2
  • 33
    • 0015536360 scopus 로고
    • Alveolar clearance of aerosols
    • Morrow PE. Alveolar clearance of aerosols. Arch Int Med 1973;131:101-8.
    • (1973) Arch Int Med , vol.131 , pp. 101-108
    • Morrow, P.E.1
  • 34
    • 26944474854 scopus 로고    scopus 로고
    • Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery
    • Heyder J. Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery. Proc Am Thoracic Soc 2004;1:315-20.
    • (2004) Proc Am Thoracic Soc , vol.1 , pp. 315-320
    • Heyder, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.