메뉴 건너뛰기




Volumn 7, Issue 3, 2012, Pages 114-127

Cytotoxic effects of multiple N-nitrosamines in human liver cell line Hep2G: Possible mechanisms of action

Author keywords

Cell damage; Hep2G cells; Mechanisms of action; N nitrosamines

Indexed keywords

GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; NITROSAMINE; SUPEROXIDE DISMUTASE;

EID: 84861933180     PISSN: 1816496X     EISSN: 2152100X     Source Type: Journal    
DOI: 10.3923/jpt.2012.114.127     Document Type: Article
Times cited : (3)

References (56)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi, H, 1984. Catalase in vitro. Methods Enzymol., 105: 121-126.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 0025247903 scopus 로고
    • Apoptosis: The role of the endonuclease
    • Arends, M.J., R.G. Moris and A.H. Wyllie, 1990. Apoptosis: The role of the endonuclease. Am. J. Pathol, 136: 593-608.
    • (1990) Am. J. Pathol , vol.136 , pp. 593-608
    • Arends, M.J.1    Moris, R.G.2    Wyllie, A.H.3
  • 3
    • 35648994838 scopus 로고    scopus 로고
    • Protective effect of vitamin C towards N-nitrosamineinduced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay
    • Arranz, N, A.I. Haza, A. Garcia, J. Rafter and P. Morales, 2007. Protective effect of vitamin C towards N-nitrosamineinduced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Toxicol. In vitro, 21: 1311-1317.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 1311-1317
    • Arranz, N.1    Haza, A.I.2    Garcia, A.3    Rafter, J.4    Morales, P.5
  • 4
    • 0025905583 scopus 로고
    • Potential of endogenous formation of volatile nitrosamines from Nigerian vegetables and spices
    • Atawodi, S.E, E.N. Maduagwu, R. Preussmann and B. Spiegelhalder, 1991. Potential of endogenous formation of volatile nitrosamines from Nigerian vegetables and spices. Cancer Lett, 57: 219-222.
    • (1991) Cancer Lett , vol.57 , pp. 219-222
    • Atawodi, S.E.1    Maduagwu, E.N.2    Preussmann, R.3    Spiegelhalder, B.4
  • 5
    • 0021274519 scopus 로고
    • Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach
    • Autrup, H, C.C. Harris, W. Sao-Mmg, B. Lo-Yao and P. Xu-Fang et al, 1984. Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach. Chem. Biol. Interact, 50: 15-25.
    • (1984) Chem. Biol. Interact , vol.50 , pp. 15-25
    • Autrup, H.1    Harris, C.C.2    Sao-Mmg, W.3    Lo-Yao, B.4    Xu-Fang, P.5
  • 6
    • 0030484004 scopus 로고    scopus 로고
    • In vitro effect of n-nitro so diethyl amine on lipid peroxidation and antioxidant system in human erythrocytes
    • Bansal, A.K, D. Bhatnagar and G.L. Soni, 1996. In vitro effect of n-nitro so diethyl amine on lipid peroxidation and antioxidant system in human erythrocytes. Toxicol. In vitro, 10: 649-653.
    • (1996) Toxicol. In Vitro , vol.10 , pp. 649-653
    • Bansal, A.K.1    Bhatnagar, D.2    Soni, G.L.3
  • 7
    • 0024814876 scopus 로고
    • Carcinogenic nitrosamines: Free radical aspects of their action
    • Bartsch, H, E. Hietanen and C. Malaveille, 1989. Carcinogenic nitrosamines: Free radical aspects of their action. Free Radical Biol. Med, 7: 637-644.
    • (1989) Free Radical Biol. Med , vol.7 , pp. 637-644
    • Bartsch, H.1    Hietanen, E.2    Malaveille, C.3
  • 8
    • 80052402338 scopus 로고    scopus 로고
    • Solid-phase extraction and high-performance liquid chromatography mass spectrometry analysis of nitrosamines in treated drinking water and wastewater
    • Boyd, J.M, S.E. Hrudey and X.F. Li, 2011. Solid-phase extraction and high-performance liquid chromatography mass spectrometry analysis of nitrosamines in treated drinking water and wastewater. TrAC Trends Anal. Chem, 30: 1410-1421.
    • (2011) TrAC Trends Anal. Chem , vol.30 , pp. 1410-1421
    • Boyd, J.M.1    Hrudey, S.E.2    Li, X.F.3
  • 10
    • 0026555808 scopus 로고
    • Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis
    • Collins, R.J., B.V. Harmon, G.C. Gobe and J.F. Kerr, 1992. Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int. J. Radiat. Biol., 61: 451-453.
    • (1992) Int. J. Radiat. Biol , vol.61 , pp. 451-453
    • Collins, R.J.1    Harmon, B.V.2    Gobe, G.C.3    Kerr, J.F.4
  • 11
    • 0023201205 scopus 로고
    • Glutathione depleting agents and lipid peroxidation
    • Comporti, M., 1987. Glutathione depleting agents and lipid peroxidation. Chem. Phys. Lipids, 45: 143-169.
    • (1987) Chem. Phys. Lipids , vol.45 , pp. 143-169
    • Comporti, M.1
  • 13
    • 0031036984 scopus 로고    scopus 로고
    • Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)
    • Darzynkiewicz, Z., G. Juan, X. Li, W. Gorczyca, T. Murakami and F. Traganos, 1997. Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis). Cytometry, 27: 1-20.
    • (1997) Cytometry , vol.27 , pp. 1-20
    • Darzynkiewicz, Z.1    Juan, G.2    Li, X.3    Gorczyca, W.4    Murakami, T.5    Traganos, F.6
  • 14
    • 77957706921 scopus 로고    scopus 로고
    • Hepatoprotective effect of Cassia auriculata L. leaf extract on carbon tetrachloride intoxicated liver damage in Wister albino rats
    • Dhanasekaran, J.J. and M. Ganapathy, 2011. Hepatoprotective effect of Cassia auriculata L. leaf extract on carbon tetrachloride intoxicated liver damage in Wister albino rats. Asian J. Biochem, 6: 104-112.
    • (2011) Asian J. Biochem , vol.6 , pp. 104-112
    • Dhanasekaran, J.J.1    Ganapathy, M.2
  • 15
    • 33845504856 scopus 로고    scopus 로고
    • Phytochelatins as a biomarker for cu-toxicity in soybean callus cultures
    • El-Enany, A.A., 2000. Phytochelatins as a biomarker for cu-toxicity in soybean callus cultures. Pak. J. Biol. Sci, 3: 799-803.
    • (2000) Pak. J. Biol. Sci , vol.3 , pp. 799-803
    • El-Enany, A.A.1
  • 16
    • 0016414528 scopus 로고
    • Superoxide dismutases
    • Fridovich, I., 1975. Superoxide dismutases. Ann. Rev. Biochem., 44: 147-159.
    • (1975) Ann. Rev. Biochem , vol.44 , pp. 147-159
    • Fridovich, I.1
  • 17
    • 77956571698 scopus 로고    scopus 로고
    • Basil (Ocimum basilicum and Ocimum tenuiflorum) reduces azoxymethane induced colon tumors in fisher 344 male rats
    • Gajula, D., M. Verghese, J. Boateng, L. Shackelford and S.R. Mentreddy et al., 2010. Basil (Ocimum basilicum and Ocimum tenuiflorum) reduces azoxymethane induced colon tumors in fisher 344 male rats. Res. J. Phytochem., 4: 136-145.
    • (2010) Res. J. Phytochem , vol.4 , pp. 136-145
    • Gajula, D.1    Verghese, M.2    Boateng, J.3    Shackelford, L.4    Mentreddy, S.R.5
  • 18
    • 71549173131 scopus 로고    scopus 로고
    • N-nitrosopiperidine and n- nitrosodibutylamine induce apoptosis in Hepg2 cells via the caspase dependent pathway
    • Garcia, A., P. Morales, J. Rafter and A.I. Haza, 2009. N-nitrosopiperidine and n- nitrosodibutylamine induce apoptosis in Hepg2 cells via the caspase dependent pathway. Cell Biol. Int., 33: 1280-1286.
    • (2009) Cell Biol. Int , vol.33 , pp. 1280-1286
    • Garcia, A.1    Morales, P.2    Rafter, J.3    Haza, A.I.4
  • 19
    • 84861946827 scopus 로고    scopus 로고
    • Induction of apoptosis and reactive oxygen species production by n-nitrosopiperidine and n-nitrosodibutylamine in human leukemia cells
    • S66-S66
    • Garcia, A., P. Morales, N. Arranz, E. Delgado and A.I. Haza, 2007. Induction of apoptosis and reactive oxygen species production by n-nitrosopiperidine and n-nitrosodibutylamine in human leukemia cells. Toxicol. Lett., 172: S66-S66.
    • (2007) Toxicol. Lett , vol.172
    • Garcia, A.1    Morales, P.2    Arranz, N.3    Delgado, E.4    Haza, A.I.5
  • 20
    • 0018576366 scopus 로고
    • Analysis of volatile n-nitrosamines in alcoholic beverages
    • Goff, E.U. and D.H. Fine, 1979. Analysis of volatile n-nitrosamines in alcoholic beverages. Food Cosmet. Toxicol., 17: 569-573.
    • (1979) Food Cosmet. Toxicol , vol.17 , pp. 569-573
    • Goff, E.U.1    Fine, D.H.2
  • 21
    • 64749084099 scopus 로고    scopus 로고
    • Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire
    • 10.1186/1475-2891-8-16
    • Gnesenbeck, J.S., M.D. Steck, J.C. Huber, J.R. Sharkey, A.A. Rene and J.D. Brender, 2009. Development of estimates of dietary nitrates, nitrites, and nitrosamines for use with the short willet food frequency questionnaire. Nutr. J., Vol. 8. 10.1186/1475-2891-8-16
    • (2009) Nutr. J , vol.8
    • Gnesenbeck, J.S.1    Steck, M.D.2    Huber, J.C.3    Sharkey, J.R.4    Rene, A.A.5    Brender, J.D.6
  • 22
    • 77954360443 scopus 로고    scopus 로고
    • Radical mechanisms in nitros amine- and nitros amide -induced whole-genome gene expression modulations in Caco-2 cells
    • Hebels, D.G., J.J. Briede, R. Khampang, J.C. Kleinjans and T.M. de Kok, 2010. Radical mechanisms in nitros amine- and nitros amide -induced whole-genome gene expression modulations in Caco-2 cells. Toxicolog. Sci.: Off. J. Soc. Toxicol., 116: 194-205.
    • (2010) Toxicolog. Sci.: Off. J. Soc. Toxicol , vol.116 , pp. 194-205
    • Hebels, D.G.1    Briede, J.J.2    Khampang, R.3    Kleinjans, J.C.4    de Kok, T.M.5
  • 23
    • 0028796225 scopus 로고
    • Defining apoptosis
    • Hockenbery, D., 1995. Defining apoptosis. Am. J. Pathol., 146: 16-19.
    • (1995) Am. J. Pathol , vol.146 , pp. 16-19
    • Hockenbery, D.1
  • 24
    • 19444383488 scopus 로고    scopus 로고
    • Genotoxicity of heat-processed foods
    • Jagerstad, M. and K. Skog, 2005. Genotoxicity of heat-processed foods. Mutat. Res., 574: 156-172.
    • (2005) Mutat. Res , vol.574 , pp. 156-172
    • Jagerstad, M.1    Skog, K.2
  • 25
    • 0041703049 scopus 로고    scopus 로고
    • Analysis of tobacco-specific n-nitrosamines in snuff by ethyl acetate extraction and liquid chromatography-tandem mass spectrometry
    • Jansson, C, A. Paccou and B.G. Osterdahl, 2003. Analysis of tobacco-specific n-nitrosamines in snuff by ethyl acetate extraction and liquid chromatography-tandem mass spectrometry. J. Chromatogr. A, 1008: 135-143.
    • (2003) J. Chromatogr. A , vol.1008 , pp. 135-143
    • Jansson, C.1    Paccou, A.2    Osterdahl, B.G.3
  • 26
    • 35348960566 scopus 로고    scopus 로고
    • DEN-Induced cancer and its alleviation by Anisomeles malabarica (L.) R.Br, ethanolic leaf extract in male albino mice
    • Jeyachandran, R., A. Mahesh and L. Cindrella, 2007. DEN-Induced cancer and its alleviation by Anisomeles malabarica (L.) R.Br, ethanolic leaf extract in male albino mice. Int. J. Cancer Res., 3: 174-179.
    • (2007) Int. J. Cancer Res , vol.3 , pp. 174-179
    • Jeyachandran, R.1    Mahesh, A.2    Cindrella, L.3
  • 27
    • 77954751617 scopus 로고    scopus 로고
    • Intracellular mechanisms of apoptosis
    • Khan, A.A., 2010. Intracellular mechanisms of apoptosis. J. Biol. Sci., 10: 291-305.
    • (2010) J. Biol. Sci , vol.10 , pp. 291-305
    • Khan, A.A.1
  • 28
    • 69949098240 scopus 로고    scopus 로고
    • Occurrence and removal of 7V-nitrosamines in wastewater treatment plants
    • Krauss, M., P. Longree, F. Dorusch, C. Ort and J. Hollender, 2009. Occurrence and removal of 7V-nitrosamines in wastewater treatment plants. Water Res., 43: 4381-4391.
    • (2009) Water Res , vol.43 , pp. 4381-4391
    • Krauss, M.1    Longree, P.2    Dorusch, F.3    Ort, C.4    Hollender, J.5
  • 29
    • 0034122382 scopus 로고    scopus 로고
    • Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing cyp2el or cyp2a6 together with human NADPH-cytochrome p450 reductase
    • Kushida, H, K.I. Fujita, A. Suzuki, M. Yamada, T. Endo, T. Nohmi and T. Kamataki, 2009. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing cyp2el or cyp2a6 together with human NADPH-cytochrome p450 reductase. Carcinogenesis, 21: 1227-1232.
    • (2009) Carcinogenesis , vol.21 , pp. 1227-1232
    • Kushida, H.1    Fujita, K.I.2    Suzuki, A.3    Yamada, M.4    Endo, T.5    Nohmi, T.6    Kamataki, T.7
  • 30
    • 0033801495 scopus 로고    scopus 로고
    • Excretion of volatile nitrosamines in a rural population in relation to food and drinking water consumption
    • Levallois, P., P. Ayotte, J.M. van Maanen, T. Desrosiers and S. Gingras et al., 2000. Excretion of volatile nitrosamines in a rural population in relation to food and drinking water consumption. Food Chem. Toxicol, 38: 1013-1019.
    • (2000) Food Chem. Toxicol , vol.38 , pp. 1013-1019
    • Levallois, P.1    Ayotte, P.2    van Maanen, J.M.3    Desrosiers, T.4    Gingras, S.5
  • 31
    • 33745211212 scopus 로고    scopus 로고
    • The potential impact of a low-nitrosamine smokeless tobacco product on cigarette smoking in the united states: Estimates of a panel of experts
    • Levy, D.T, E.A. Mumford, K.M. Cummmgs, E.A. Gilpin and G.A. Giovmo et al, 2006. The potential impact of a low-nitrosamine smokeless tobacco product on cigarette smoking in the united states: Estimates of a panel of experts. Addictive Behaviors, 31: 1190-1200.
    • (2006) Addictive Behaviors , vol.31 , pp. 1190-1200
    • Levy, D.T.1    Mumford, E.A.2    Cummmgs, K.M.3    Gilpin, E.A.4    Giovmo, G.A.5
  • 32
    • 0003411354 scopus 로고
    • Cambridge University Press, Cambridge, UK, ISBN-13: 9780521346290, 464
    • Lijinsky, W, 1992. Chemistry and Biology of N-Nitroso Compounds. Cambridge University Press, Cambridge, UK, ISBN-13: 9780521346290, Pages: 464.
    • (1992) Chemistry and Biology of N-Nitroso Compounds
    • Lijinsky, W.1
  • 34
    • 0033152848 scopus 로고    scopus 로고
    • N-nitrosodimethylamine-mediated cytotoxicity in a cell line expressing p450 2el: Evidence for apoptotic cell death
    • Lin, H.L, L.A. Parsels, J. Maybaum and P.F. Hollenberg, 1999. N-nitrosodimethylamine-mediated cytotoxicity in a cell line expressing p450 2el: Evidence for apoptotic cell death. Toxicol Applied Pharm, 157: 117-124.
    • (1999) Toxicol Applied Pharm , vol.157 , pp. 117-124
    • Lin, H.L.1    Parsels, L.A.2    Maybaum, J.3    Hollenberg, P.F.4
  • 35
    • 33644911463 scopus 로고    scopus 로고
    • Detoxification and biotransformational imbalances
    • Liska, D, M. Lyon and D.S. Jones, 2006. Detoxification and biotransformational imbalances. Explore: J. Sci. Healing, 2: 122-140.
    • (2006) Explore: J. Sci. Healing , vol.2 , pp. 122-140
    • Liska, D.1    Lyon, M.2    Jones, D.S.3
  • 36
    • 0002406740 scopus 로고
    • N-nitroso Compounds and Related Carcinogens
    • Searle, C.S. (Ed.). American Chemical Society, Washington D.C
    • Magee, P.N, R. Montesano and R. Preussman, 1976. N-nitroso Compounds and Related Carcinogens. In: Chemical Carcingogens, Searle, C.S. (Ed.). American Chemical Society, Washington D.C, pp: 491-626.
    • (1976) Chemical Carcingogens , pp. 491-626
    • Magee, P.N.1    Montesano, R.2    Preussman, R.3
  • 37
    • 33644518999 scopus 로고    scopus 로고
    • Effects of s-allyl cysteine on n-nitrosodiethylamine induced hepatocarcinogenesis: Variations in temporal patterns of circulatory tumor marker enzymes
    • Manivasagam, T, S. Perumal, E. Musthafa Mohamed, S.S. Ganapathy Suthakar and S. Ramar, 2006. Effects of s-allyl cysteine on n-nitrosodiethylamine induced hepatocarcinogenesis: variations in temporal patterns of circulatory tumor marker enzymes. Int. J. Pharmacol, 2: 136-141.
    • (2006) Int. J. Pharmacol , vol.2 , pp. 136-141
    • Manivasagam, T.1    Perumal, S.2    Musthafa Mohamed, E.3    Ganapathy Suthakar, S.S.4    Ramar, S.5
  • 38
    • 0024334989 scopus 로고
    • Formation of n-nitrosamines in microwaved versus skillet-fried bacon containing nitrite
    • Miller, B.J, S.M. Billedeau and D.W. Miller, 1989. Formation of n-nitrosamines in microwaved versus skillet-fried bacon containing nitrite. Food Chem. Toxicol, 27: 295-299.
    • (1989) Food Chem. Toxicol , vol.27 , pp. 295-299
    • Miller, B.J.1    Billedeau, S.M.2    Miller, D.W.3
  • 39
    • 0032802632 scopus 로고    scopus 로고
    • Exposure to N-nitroso compounds in a population of high liver cancer regions in Thailand: Volatile nitrosamine (VNA) levels in Thai food
    • Mitacek, E.J, K.D. Brunnemann, M. Suttajit, N. Martin, T. Limsila, H. Ohshima and L.S. Caplan, 1999. Exposure to N-nitroso compounds in a population of high liver cancer regions in Thailand: Volatile nitrosamine (VNA) levels in Thai food. Food Chem. Toxicol, 37: 297-305.
    • (1999) Food Chem. Toxicol , vol.37 , pp. 297-305
    • Mitacek, E.J.1    Brunnemann, K.D.2    Suttajit, M.3    Martin, N.4    Limsila, T.5    Ohshima, H.6    Caplan, L.S.7
  • 40
    • 0017069120 scopus 로고
    • Mutagenic and carcinogenic n-nitroso compounds: Possible environmental hazards
    • Montesano, R. and H. Bartsch, 1976. Mutagenic and carcinogenic n-nitroso compounds: Possible environmental hazards. Mutation Res. Rev. Genet. Toxicol, 32: 179-227.
    • (1976) Mutation Res. Rev. Genet. Toxicol , vol.32 , pp. 179-227
    • Montesano, R.1    Bartsch, H.2
  • 41
    • 84856061154 scopus 로고    scopus 로고
    • The salutary role of Allium cepa extract on the liver histology, liver Oxydative status and liver marker enzymes of rabbits submitted to Alcohol-induced toxicity
    • Ogunlade, B, L.C. Saalu, O.S. Ogunmodede, G.G. Akunna, O.A. Adeeyo and G.O. Ajayi, 2012. The salutary role of Allium cepa extract on the liver histology, liver Oxydative status and liver marker enzymes of rabbits submitted to Alcohol-induced toxicity. Am. J. Biochem. Mol. Biol, 2:67-81.
    • (2012) Am. J. Biochem. Mol. Biol , vol.2 , pp. 67-81
    • Ogunlade, B.1    Saalu, L.C.2    Ogunmodede, O.S.3    Akunna, G.G.4    Adeeyo, O.A.5    Ajayi, G.O.6
  • 42
    • 0035170912 scopus 로고    scopus 로고
    • Review toxicological evaluation of nitrosamines in condoms
    • Proksch E, 2001. Review toxicological evaluation of nitrosamines in condoms. Int. J. Hyg. Environ. Health, 204: 103-110.
    • (2001) Int. J. Hyg. Environ. Health , vol.204 , pp. 103-110
    • Proksch, E.1
  • 43
  • 44
    • 0037043596 scopus 로고    scopus 로고
    • Effects of vitamins C and E on cytotoxicity induced by n- nitroso compounds, n-nitrosomorpholine and n-methyl-n'-nitro-n-nitrosoguanidine in caco-2 and v79 cell lines
    • Robichova, S. and D. Slamenova, 2002. Effects of vitamins C and E on cytotoxicity induced by n- nitroso compounds, n-nitrosomorpholine and n-methyl-n'-nitro-n-nitrosoguanidine in caco-2 and v79 cell lines. Cancer Lett, 182: 11-18.
    • (2002) Cancer Lett , vol.182 , pp. 11-18
    • Robichova, S.1    Slamenova, D.2
  • 46
    • 20544472084 scopus 로고    scopus 로고
    • Evaluation of dip he nyl amine derivatives in apple peel using gradient reversed-phase liquid chromatography with ultraviolet-visible absorption and atmospheric pressure chemical ionization mass selective detection
    • Rudell, D.R., J.P. Mattheis and J.K. Fellman, 2005. Evaluation of dip he nyl amine derivatives in apple peel using gradient reversed-phase liquid chromatography with ultraviolet-visible absorption and atmospheric pressure chemical ionization mass selective detection. J. Chromatogr. A, 1081: 202-209.
    • (2005) J. Chromatogr. A , vol.1081 , pp. 202-209
    • Rudell, D.R.1    Mattheis, J.P.2    Fellman, J.K.3
  • 47
    • 0024555692 scopus 로고
    • Determination of non-volatile n-nitros amines in baby bottle rubber nipples and pacifiers by high-performance liquid chromatography-thermal energy analysis
    • Sen, N.P., S.W. Seaman and S.C. Kushwaha, 1989. Determination of non-volatile n-nitros amines in baby bottle rubber nipples and pacifiers by high-performance liquid chromatography-thermal energy analysis. J. Chromatogr. A, 463: 419-428.
    • (1989) J. Chromatogr. A , vol.463 , pp. 419-428
    • Sen, N.P.1    Seaman, S.W.2    Kushwaha, S.C.3
  • 48
    • 0028859156 scopus 로고
    • Recovery of the hepatic carcinogen-metabolizing capacity in schistosome-infected mice after treatment with the antischistosomal praziquantel
    • Sheweita, S. and M. Mostafa, 1995. Recovery of the hepatic carcinogen-metabolizing capacity in schistosome-infected mice after treatment with the antischistosomal praziquantel. Oncol. Rep., 1: 155-159.
    • (1995) Oncol. Rep , vol.1 , pp. 155-159
    • Sheweita, S.1    Mostafa, M.2
  • 49
    • 0029671178 scopus 로고    scopus 로고
    • N-nitrosamines and their effects on the level of glutathione, glutathione reductase and glutathione s-transferase activities in the liver of male mice
    • Sheweita, S.A. and M.H. Mostafa, 1996. N-nitrosamines and their effects on the level of glutathione, glutathione reductase and glutathione s-transferase activities in the liver of male mice. Cancer Lett., 99: 29-34.
    • (1996) Cancer Lett , vol.99 , pp. 29-34
    • Sheweita, S.A.1    Mostafa, M.H.2
  • 50
    • 33646192289 scopus 로고    scopus 로고
    • Pistachio extracts effects on the aflatoxin Bl cytotoxicity in HepG2 cells
    • Shirazi, S.H., H. Yazdanpanah, F. Khoshjoo and L. Hosseinzadeh, 2006. Pistachio extracts effects on the aflatoxin Bl cytotoxicity in HepG2 cells. Int. J. Pharmacol., 2: 233-239.
    • (2006) Int. J. Pharmacol , vol.2 , pp. 233-239
    • Shirazi, S.H.1    Yazdanpanah, H.2    Khoshjoo, F.3    Hosseinzadeh, L.4
  • 51
    • 0023920761 scopus 로고
    • N-nitrosamines in Chinese foods
    • Song, P.J. and J.F. Hu, 1988. N-nitrosamines in Chinese foods. Food Chem. Toxicol., 26: 205-208.
    • (1988) Food Chem. Toxicol , vol.26 , pp. 205-208
    • Song, P.J.1    Hu, J.F.2
  • 52
    • 77957283864 scopus 로고    scopus 로고
    • Nutritional carcinogenesis
    • Sutandyo, N, 2010. Nutritional carcinogenesis. Acta Med Indonesiana, 42: 36-42.
    • (2010) Acta Med Indonesiana , vol.42 , pp. 36-42
    • Sutandyo, N.1
  • 53
    • 33745221877 scopus 로고    scopus 로고
    • Anticarcinogenic effect of phytic acid (IPg): Apoptosis as a possible mechanism of action
    • Verghese, M., D.R. Rao, C.B. Chawan, L.T. Walker and L. Shackelford, 2006. Anticarcinogenic effect of phytic acid (IPg): Apoptosis as a possible mechanism of action. LWT-Food Sci. Technol., 39: 1093-1098.
    • (2006) LWT-Food Sci. Technol , vol.39 , pp. 1093-1098
    • Verghese, M.1    Rao, D.R.2    Chawan, C.B.3    Walker, L.T.4    Shackelford, L.5
  • 54
    • 43149121067 scopus 로고    scopus 로고
    • Chemopreventive effects of flax seed oil and flax seed meal on azoxymethane-induced colon tumors in fisher 344 male rats
    • Williams, D.S., M. Verghese, L.T. Walker, J. Boateng and L.A. Shackelford et al., 2008. Chemopreventive effects of flax seed oil and flax seed meal on azoxymethane-induced colon tumors in fisher 344 male rats. Int. J. Cancer Res., 4: 28-40.
    • (2008) Int. J. Cancer Res , vol.4 , pp. 28-40
    • Williams, D.S.1    Verghese, M.2    Walker, L.T.3    Boateng, J.4    Shackelford, L.A.5
  • 55
    • 0021328201 scopus 로고
    • Determination of volatile nitrosamine levels in foods and estimation of their daily intake in japan
    • Yamamoto, M., R. Iwata, H. Ishiwata, T. Yamada and A. Tanimura, 1984. Determination of volatile nitrosamine levels in foods and estimation of their daily intake in japan. Food Chem. Toxicol, 22: 61-64.
    • (1984) Food Chem. Toxicol , vol.22 , pp. 61-64
    • Yamamoto, M.1    Iwata, R.2    Ishiwata, H.3    Yamada, T.4    Tanimura, A.5
  • 56
    • 27644524750 scopus 로고    scopus 로고
    • Volatile n-nitrosamines in various fish products
    • Yurchenko, S. and U. Molder, 2006. Volatile n-nitrosamines in various fish products. Food Chem, 96: 325-333.
    • (2006) Food Chem , vol.96 , pp. 325-333
    • Yurchenko, S.1    Molder, U.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.