Synthesis of N-alkyl-substituted 4-quinolones via tandem alkenyl and aryl C-N bond formation

Synthesis (Germany)

Volumn 44, Issue 12, 2012, Pages 1798-1808

  Shao, Jun ^a   Huang, Xiaomei ^a   Hong, Xiaohu ^a   Liu, Bingxin ^a   Xu, Bin ^a,b,c  

^a SHANGHAI UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^c EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

alkynes; amination; cyclization; domino reactions; nitrogen heterocycles

Indexed keywords

ACETYLENIC KETONES; ALKENYL; ALKYL AMINES; ALKYNES; BOND FORMATION; DOMINO REACTIONS; FUNCTIONALIZED; HIGH YIELD; NITROGEN HETEROCYCLES; STRUCTURAL MOTIFS;

ACETYLENE; AMINATION; CYCLIZATION; KETONES; REACTION KINETICS;

AMINES;

1 (2 BROMOPHENYL) 3 PHENYLPROPYNONE; 1 (2 CHLOROPHENYL) 3 (4 ETHYLPHENYL)PROPYNONE; 1 (2 CHLOROPHENYL) 3 (4 FLUOROPHENYL)PROPYNONE; 1 (2 CHLOROPHENYL) 3 (4 METHOXYPHENYL)PROPYNONE; 1 (2 CHLOROPHENYL) 3 PHENYLPROPYNONE; 1 (2 CHLOROPHENYL)OCT 2 YN 1 ONE; 1 (2 HYDROXYETHYL) 2 PHENYL 1H QUINOLIN 4 ONE; 1 (2,4 DICHLOROPHENYL) 3 PHENYLPROPYNONE; 1 (2,4 DICHLOROPHENYL) 3 TRIMETHYLSILANYLPROPYNONE; 1 BUTYL 2 (3 CHLOROPHENYL) 1H QUINOLIN 4 ONE; 1 BUTYL 2 (4 CHLOROPHENYL) 1H QUINOLIN 4 ONE; 1 BUTYL 2 PHENYL 1H QUINOLIN 4 ONE; 1,2 DIPHENYL 1H QUINOLIN 4 ONE; 1,3 BIS(32 CHLOROPHENYL)PROPYNONE; 2 PHENYL 1 PROPENYL 1H QUINOLIN 4 ONE; 3 (3 CHLOROPHENYL) 1 (2 CHLOROPHENYL)PROPYNONE; 3 (4 CHLOROPHENYL) 1 (2 CHLOROPHENYL)PROPYNONE; 4 QUINOLONE DERIVATIVE; ALKENYL GROUP; ALKYL GROUP; BENZYL 2 PHENYL 1H QUINOLIN 4 ONE; BUTYL 2 (4 ETHYLPHENYL) 1H QUINOLIN 4 ONE; BUTYL 2 (4 METHOXY PHENYL) 1H QUINOLIN 4 ONE; CYCLOHEXYL 2 PHENYL 1H QUINOLIN 4 ONE; CYCLOPROPYL 2 PHENYL 1H QUINOLIN 4 ONE; DODECYL 2 PHENYL 1H QUINOLIN 4 ONE; ISOPROPYL 2 PHENYL 1H QUINOLIN 4 ONE; KETONE; O CHLOROARYL ACETYLENIC KETONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINATION; ARTICLE; CARBON NITROGEN BOND; CHEMICAL BOND; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 84861901922     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1290775     Document Type: Article

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