메뉴 건너뛰기




Volumn 125, Issue 22, 2012, Pages 2692-2694

Sphingosine 1-phosphate as a therapeutic target in heart failure: More questions than answers

Author keywords

Editorials; Genes; Heart failure; Sphingosine 1 phosphate; Therapeutic target; Vascular response

Indexed keywords

2 AMINO 2 (3 OCTYLPHENYLCARBAMOYL)ETHYL PHOSPHATE; 2 AMINO 2 [2 [4 (3 BENZYLOXYPHENYLTHIO) 2 CHLOROPHENYL]ETHYL] 1,3 PROPANEDIOL; 3 [2 (3 TRIFLUOROMETHYL 4 BIPHENYLYL)BENZO[B]THIEN 5 YLMETHYLAMINO]PROPIONIC ACID; 5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; AAL R; ABC 294640; ACETYLCHOLINE; COMPOUND 5; CYM 5442; FINGOLIMOD; LX 2931; MESSENGER RNA; PHENYLEPHRINE; PONESIMOD; PROHIBITIN; PROTEIN KINASE C DELTA; SAFINGOL; SK 11; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TY 52156; UNCLASSIFIED DRUG; VPC 44116; W 146;

EID: 84861872296     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.107797     Document Type: Editorial
Times cited : (10)

References (19)
  • 1
    • 67449138784 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor signalling in the heart
    • Means CK, Brown JH. Sphingosine-1-phosphate receptor signalling in the heart. Cardiovasc Res. 2009;82:193-200.
    • (2009) Cardiovasc Res , vol.82 , pp. 193-200
    • Means, C.K.1    Brown, J.H.2
  • 2
    • 0035929556 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: Modulation of cellular activity of sphingosine 1-phosphate
    • Boujaoude LC, Bradshaw-Wilder C, Mao C, Cohn J, Ogretmen B, Hannun YA, Obeid LM. Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. J Biol Chem. 2001;276:35258-35264.
    • (2001) J Biol Chem , vol.276 , pp. 35258-35264
    • Boujaoude, L.C.1    Bradshaw-Wilder, C.2    Mao, C.3    Cohn, J.4    Ogretmen, B.5    Hannun, Y.A.6    Obeid, L.M.7
  • 4
    • 0029871896 scopus 로고    scopus 로고
    • Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)
    • DOI 10.1016/0735-1097(95)00589-7
    • Torre-Amione G, Kapadia S, Benedict CR, Oral H, Young JB, Mann DL. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the studies of left ventricular dysfunction (SOLVD). J Am Coll Cardiol. 1996;27:1201-1206. (Pubitemid 26117714)
    • (1996) Journal of the American College of Cardiology , vol.27 , Issue.5 , pp. 1201-1206
    • Torre-Amione, G.1    Kapadia, S.2    Benedict, C.3    Oral, H.4    Young, J.B.5    Mann, D.L.6
  • 5
    • 0028898719 scopus 로고
    • Soluble tumor necrosis factor binding proteins modulate the negative inotropic effects of TNF-a in vitro
    • Kapadia S, Torre-Amione G, Yokoyama T, Mann DL. Soluble tumor necrosis factor binding proteins modulate the negative inotropic effects of TNF-a in vitro. Am J Physiol. 1995;37:H517-H525.
    • (1995) Am J Physiol , vol.37
    • Kapadia, S.1    Torre-Amione, G.2    Yokoyama, T.3    Mann, D.L.4
  • 8
    • 79959686782 scopus 로고    scopus 로고
    • Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system
    • Schuchardt M, Tolle M, Prufer J, van der Giet M. Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system. Br J Pharmacol. 2011;163:1140-1162.
    • (2011) Br J Pharmacol , vol.163 , pp. 1140-1162
    • Schuchardt, M.1    Tolle, M.2    Prufer, J.3    Van Der Giet, M.4
  • 12
    • 74149086892 scopus 로고    scopus 로고
    • FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling
    • Egom EE, Ke Y, Musa H, Mohamed TM, Wang T, Cartwright E, Solaro RJ, Lei M. FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling. J Mol Cell Cardiol. 2010;48:406-414.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 406-414
    • Egom, E.E.1    Ke, Y.2    Musa, H.3    Mohamed, T.M.4    Wang, T.5    Cartwright, E.6    Solaro, R.J.7    Lei, M.8
  • 14
    • 0037879072 scopus 로고    scopus 로고
    • Left ventricular diastolic function in patients with advanced cystic fibrosis
    • DOI 10.1378/chest.123.5.1488
    • Koelling TM, Dec GW, Ginns LC, Semigran MJ. Left ventricular diastolic function in patients with advanced cystic fibrosis. Chest. 2003;123: 1488-1494. (Pubitemid 36549767)
    • (2003) Chest , vol.123 , Issue.5 , pp. 1488-1494
    • Koelling, T.M.1    Dec, G.W.2    Ginns, L.C.3    Semigran, M.J.4
  • 16
    • 84861854722 scopus 로고    scopus 로고
    • Tumor necrosis factor-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure
    • Meissner A, Yang J, Kroetsch JT, Sauve M, Dax H, Momen A, Noyen-Ashraf MH, Heximer S, Hussain M, Lidington D, Bolz SS. Tumor necrosis factor-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure. Circulation. 2012;125:2739-2750.
    • (2012) Circulation , vol.125 , pp. 2739-2750
    • Meissner, A.1    Yang, J.2    Kroetsch, J.T.3    Sauve, M.4    Dax, H.5    Momen, A.6    Noyen-Ashraf, M.H.7    Heximer, S.8    Hussain, M.9    Lidington, D.10    Bolz, S.S.11
  • 17
    • 84861845133 scopus 로고    scopus 로고
    • Decreased free sphingoid base concentration in the plasma of patients with chronic systolic heart failure
    • Knapp M, Baranowski M, Lisowska A, Musial W. Decreased free sphingoid base concentration in the plasma of patients with chronic systolic heart failure. Adv Med Sci. 2012:1-6.
    • (2012) Adv Med Sci , pp. 1-6
    • Knapp, M.1    Baranowski, M.2    Lisowska, A.3    Musial, W.4
  • 18
    • 79961082952 scopus 로고    scopus 로고
    • Translational aspects of sphingosine 1-phosphate biology
    • Pyne S, Pyne NJ. Translational aspects of sphingosine 1-phosphate biology. Trends Mol Med. 2011;17:463-472.
    • (2011) Trends Mol Med , vol.17 , pp. 463-472
    • Pyne, S.1    Pyne, N.J.2
  • 19
    • 80054999107 scopus 로고    scopus 로고
    • Development of small-molecule inhibitors of sphingosine-1-phosphate signaling
    • Edmonds Y, Milstien S, Spiegel S. Development of small-molecule inhibitors of sphingosine-1-phosphate signaling. Pharmacol Ther. 2011;132:352-360.
    • (2011) Pharmacol Ther , vol.132 , pp. 352-360
    • Edmonds, Y.1    Milstien, S.2    Spiegel, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.